Francis Hickey, MD, FAAP
Professor, Pediatrics-Linda Crnic Institute for Down Syndrome

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Medical School:
  • MD, University of Cincinnati College of Medicine (1984)
Undergraduate School:
  • BA, Harvard University (MA) (1978)
Internship:
  • Cincinnati Children's Hospital Medical Center Program (1988)
Residency:
  • Cincinnati Children's Hospital Medical Center Program, Pediatrics (1990)
Fellowships:
  • Children's Hospital (Boston) Program, Pediatrics (1992)
Languages: English
Department: Pediatrics-Linda Crnic Institute for Down Syndrome

Research Interests

Dr. Hickey has conducted many research projects related to exploring development in individuals with Down syndrome and autism and has authored or co-authored numerous articles and abstracts in scholarly publications on the topic.

Publications

  • DeBoer EM, Wolter-Warmerdam K, Deterding RR, Marmolejo J, Blumenthal T, Espinosa JM, Hickey F, Wagner BD. Cardiopulmonary Phenotypes and Protein Signatures in Children With Down Syndrome. Clin Pediatr (Phila). 2023 Jun 12;:99228231179453. [Epub ahead of print] PubMed PMID: 37306037
  • Araya P, Kinning KT, Coughlan C, Smith KP, Granrath RE, Enriquez-Estrada BA, Worek K, Sullivan KD, Rachubinski AL, Wolter-Warmerdam K, Hickey F, Galbraith MD, Potter H, Espinosa JM. IGF1 deficiency integrates stunted growth and neurodegeneration in Down syndrome. Cell Rep. 2022 Dec 27;41(13):111883. PubMed PMID: 36577365
  • Harvey S, Wolter-Warmerdam K, Hickey F, Daniels D, DomBourian M, Ambruso DR, McKinney C. Blood counts in children with Down syndrome. Pediatr Blood Cancer. 2022 Dec;69(12):e30002. PubMed PMID: 36151966
  • Barreiro A, Wolter-Warmerdam K, Friedman S, Hickey F, Johnson S, Marmolejo J. Child feeding practices in children with Down syndrome in relationship to ethnicity and BMI. Appetite. 2022 Mar 1;170:105888. PubMed PMID: 34953969
  • Daniels D, Wolter-Warmerdam K, Holland S, Hickey F. Reach Out and Read Implementation in a Pediatric Down Syndrome Clinic. J Pediatr Health Care. 2022 May-Jun;36(3):231-239. PubMed PMID: 34879985
  • Araya P, Kinning KT, Coughlan C, Smith KP, Granrath RE, Enriquez-Estrada BA, Worek K, Sullivan KD, Rachubinski AL, Wolter-Warmerdam K, Hickey F, Galbraith MD, Potter H, Espinosa JM. IGF1 deficiency integrates stunted growth and neurodegeneration in Down syndrome. Cell Rep. 2022 Dec 27;41(13):111883. PubMed PMID: 36577365
  • Harvey S, Wolter-Warmerdam K, Hickey F, Daniels D, DomBourian M, Ambruso DR, McKinney C. Blood counts in children with Down syndrome. Pediatr Blood Cancer. 2022 Dec;69(12):e30002. PubMed PMID: 36151966
  • McCarthy S, Henderson K, Skinner C, Arreola LDS, Ng CJ, Jamil AN, Van de Voorde P, Cevik AA, von Schickfus M, Santos R, Jakubaszko J, Bognar Z, Baden D, Schmitz G, Pin MM, Beirne GJ, Kaji A, Løvstakken K, Siu A, Johnson K, Lim SHC, Tapia JDL, Ømark H, Moreno LA, Morphet J, Stebbeings S, Hickey F. Health-care workers and facilities in Ukraine must be protected. Lancet. 2022 Apr 2;399(10332):1299. PubMed PMID: 35338859
  • Barreiro A, Wolter-Warmerdam K, Friedman S, Hickey F, Johnson S, Marmolejo J. Child feeding practices in children with Down syndrome in relationship to ethnicity and BMI. Appetite. 2022 Mar 1;170:105888. PubMed PMID: 34953969
  • Daniels D, Wolter-Warmerdam K, Holland S, Hickey F. Reach Out and Read Implementation in a Pediatric Down Syndrome Clinic. J Pediatr Health Care. 2022 May-Jun;36(3):231-239. PubMed PMID: 34879985
  • Vielkind ML, Hamlington KL, Wolter-Warmerdam K, Meier MR, Liu AH, Hickey FJ, Brown MA, DeBoer EM. Airwave oscillometry to measure lung function in children with Down syndrome. Pediatr Res. 2022 Jun;91(7):1775-1780. PubMed PMID: 34326475
  • Griffiths M, Yang J, Vaidya D, Nies M, Brandal S, Ivy DD, Hickey F, Wolter-Warmerdam K, Austin ED, Mullen M, Pauciulo MW, Lutz KA, Rosenzweig EB, Hirsch R, Yung D, Nichols WC, Everett AD. Biomarkers of Pulmonary Hypertension Are Altered in Children with Down Syndrome and Pulmonary Hypertension. J Pediatr. 2022 Feb;241:68-76.e3. PubMed PMID: 34687693
  • Vielkind ML, Hamlington KL, Wolter-Warmerdam K, Meier MR, Liu AH, Hickey FJ, Brown MA, DeBoer EM. Airwave oscillometry to measure lung function in children with Down syndrome. Pediatr Res. 2022 Jun;91(7):1775-1780. PubMed PMID: 34326475
  • Griffiths M, Yang J, Vaidya D, Nies M, Brandal S, Ivy DD, Hickey F, Wolter-Warmerdam K, Austin ED, Mullen M, Pauciulo MW, Lutz KA, Rosenzweig EB, Hirsch R, Yung D, Nichols WC, Everett AD. Biomarkers of Pulmonary Hypertension Are Altered in Children with Down Syndrome and Pulmonary Hypertension. J Pediatr. 2022 Feb;241:68-76.e3. PubMed PMID: 34687693
  • Barreiro A, Wolter-Warmerdam K, Friedman S, Hickey F, Johnson S, Marmolejo J. Child feeding practices in children with Down syndrome in relationship to ethnicity and BMI. Appetite. 2021 Dec 23;170:105888. [Epub ahead of print] PubMed PMID: 34953969
  • Daniels D, Wolter-Warmerdam K, Holland S, Hickey F. Reach Out and Read Implementation in a Pediatric Down Syndrome Clinic. J Pediatr Health Care. 2021 Dec 5. [Epub ahead of print] PubMed PMID: 34879985
  • Griffiths M, Yang J, Vaidya D, Nies M, Brandal S, Ivy DD, Hickey F, Wolter-Warmerdam K, Austin ED, Mullen M, Pauciulo MW, Lutz KA, Rosenzweig EB, Hirsch R, Yung D, Nichols WC, Everett AD. Biomarkers of Pulmonary Hypertension Are Altered in Children with Down Syndrome and Pulmonary Hypertension. J Pediatr. 2021 Oct 21. [Epub ahead of print] PubMed PMID: 34687693
  • Vielkind ML, Hamlington KL, Wolter-Warmerdam K, Meier MR, Liu AH, Hickey FJ, Brown MA, DeBoer EM. Airwave oscillometry to measure lung function in children with Down syndrome. Pediatr Res. 2021 Jul 29. [Epub ahead of print] PubMed PMID: 34326475
  • Vielkind M, Wolter-Warmerdam K, Jackson A, Maybee J, Brown M, Friedlander J, Friedman N, Hickey F, Prager J, Wine T, DeBoer E. Airway obstruction and inflammation on combined bronchoscopy in children with Down syndrome. Pediatr Pulmonol. 2021 Sep;56(9):2932-2939. PubMed PMID: 34245494
  • Maybee J, Jackson A, Wolter-Warmerdam K, Hickey F, Prager J, DeBoer E. Validation of the Childhood Dysphagia Management Scale (CDMS): An Impact Scale for determining medical home for dysphagia. Int J Pediatr Otorhinolaryngol. 2021 Jun;145:110716. PubMed PMID: 33892340
  • Citation: Liu, E., Wolter-Warmerdam, K., Marmolejo, J., Daniels, D., Prince, G., & Hickey, F. (2020). Routine Screening for Celiac Disease in Children With Down Syndrome Improves Case Finding. Journal of pediatric gastroenterology and nutrition, 71(2), 252-256.
  • Citation: Nightengale, E. E., Wolter-Warmerdam, K., Yoon, P. J., Daniels, D., & Hickey, F. (2020). Behavioral Audiology Procedures in Children With Down Syndrome. American Journal of Audiology, 29(3), 356-364.
  • Keratoconus and corneal morphology in patients with Down syndrome at a pediatric hospital. Imbornoni LM, Wise RE, Taravella MJ, Hickey F, McCourt EA. J AAPOS. 2020 Jun;24(3):140.e1-140.e5. doi: 10.1016/j.jaapos.2020.02.004. Epub 2020 May 27. PMID: 32473288
  • Jackson A, Maybee J, Wolter-Warmerdam K, DeBoer E, Hickey F. Associations between age, respiratory comorbidities, and dysphagia in infants with down syndrome. Pediatr Pulmonol. 2019 Nov;54(11):1853-1859. PubMed PMID: 31402588
  • Bush D, Wolter-Warmerdam K, Wagner BD, Galambos C, Ivy DD, Abman S, McMorrow D, Hickey F. EXPRESS: Angiogenic Profile Identifies Pulmonary Hypertension in Children with Down Syndrome. Pulm Circ. 2019 Jul 11;:2045894019866549. [Epub ahead of print] PubMed PMID: 31293212
  • Ruiz AG, Gao D, Ingram DG, Hickey F, Haemer MA, Friedman NR. Does Tonsillectomy Increase Obesity Risk in Children with Down Syndrome?. J Pediatr. 2019 Aug;211:179-184.e1. PubMed PMID: 31084917
  • Daniels D, Knupp K, Benke T, Wolter-Warmerdam K, Moran M, Hickey F. Infantile Spasms in Children With Down Syndrome: Identification and Treatment Response. Glob Pediatr Health. 2019;6:2333794X18821939. PubMed PMID: 30671494
  • Winders P, Wolter-Warmerdam K, Hickey F. A schedule of gross motor development for children with Down syndrome. J Intellect Disabil Res. 2019 Apr;63(4):346-356. PubMed PMID: 30575169
  • Winders P, Wolter-Warmerdam K, Hickey F. A schedule of gross motor development for children with Down syndrome. J Intellect Disabil Res. 2018 Dec 21. [Epub ahead of print] PubMed PMID: 30575169
  • Bush D, Galambos C, Ivy DD, Abman SH, Wolter-Warmerdam K, Hickey F. Clinical Characteristics and Risk Factors for Developing Pulmonary Hypertension in Children with Down Syndrome. J Pediatr. 2018 Nov;202:212-219.e2. PubMed PMID: 30025669
  • Palat P, Hickey F, Patel L, Sannar E. Levodopa-Responsive Early-Onset Parkinsonism in Down Syndrome. Case Rep Neurol Med. 2018;2018:2314791. PubMed PMID: 29666730
  • Goot BH, Kaufman J, Pan Z, Bourne DWA, Hickey F, Twite M, Galinkin J, Christians U, Zuk J, da Cruz EM. Morphine Pharmacokinetics in Children With Down Syndrome Following Cardiac Surgery. Pediatr Crit Care Med. 2018 May;19(5):459-467. PubMed PMID: 29547456
  • Nightengale E, Yoon P, Wolter-Warmerdam K, Daniels D, Hickey F. Understanding Hearing and Hearing Loss in Children With Down Syndrome. Am J Audiol. 2017 Sep 18;26(3):301-308. PubMed PMID: 28854301
  • Sullivan KD, Evans D, Pandey A, Hraha TH, Smith KP, Markham N, Rachubinski AL, Wolter-Warmerdam K, Hickey F, Espinosa JM, Blumenthal T. Trisomy 21 causes changes in the circulating proteome indicative of chronic autoinflammation. Sci Rep. 2017 Nov 1;7(1):14818. PubMed PMID: 29093484
  • Jackson A, Maybee J, Moran MK, Wolter-Warmerdam K, Hickey F. Clinical Characteristics of Dysphagia in Children with Down Syndrome. Dysphagia. 2016 Oct;31(5):663-71. PubMed PMID: 27405422
  • Santoro SL, Esbensen AJ, Hopkin RJ, Hendershot L, Hickey F, Patterson B. Contributions to Racial Disparity in Mortality among Children with Down Syndrome. J Pediatr. 2016 Jul;174:240-246.e1. PubMed PMID: 27063805
  • Jackson A, Maybee J, Moran MK, Wolter-Warmerdam K, Hickey F. Clinical Characteristics of Dysphagia in Children with Down Syndrome. Dysphagia. 2016 Oct;31(5):663-71. PubMed PMID: 27405422
  • Santoro SL, Esbensen AJ, Hopkin RJ, Hendershot L, Hickey F, Patterson B. Contributions to Racial Disparity in Mortality among Children with Down Syndrome. J Pediatr. 2016 Jul;174:240-246.e1. PubMed PMID: 27063805
  • Jacola LM, Byars AW, Hickey F, Vannest J, Holland SK, Schapiro MB. Functional magnetic resonance imaging of story listening in adolescents and young adults with Down syndrome: evidence for atypical neurodevelopment. J Intellect Disabil Res. 2014 Oct;58(10):892-902. PubMed PMID: 23962356
  • Jacola LM, Byars AW, Hickey F, Vannest J, Holland SK, Schapiro MB. Functional magnetic resonance imaging of story listening in adolescents and young adults with Down syndrome: evidence for atypical neurodevelopment. J Intellect Disabil Res. 2014 Oct;58(10):892-902. PubMed PMID: 23962356
  • Jacola LM, Byars AW, Hickey F, Vannest J, Holland SK, Schapiro MB. Functional magnetic resonance imaging of story listening in adolescents and young adults with Down syndrome: evidence for atypical neurodevelopment. J Intellect Disabil Res. 2013 Aug 20. [Epub ahead of print] PubMed PMID: 23962356
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Practice Locations

Children's Hospital Colorado Anschutz Medical Campus
13123 East 16th Ave
Aurora, CO 80045
720-777-1234

Children's Hospital Colorado Child Health Clinic
860 N Potomac Cir
Aurora, CO 80011
720-777-2740

Hospital Affiliation
  • Children's Hospital Colorado
Center Affiliations

Specialty Information

Specialties
  • Pediatrics, Board Certification (2003)

General Information

Medical Schools:
  • MD, University of Cincinnati College of Medicine (1984)
Undergraduate Schools:
  • BA, Harvard University (MA) (1978)
Internships:
  • Cincinnati Children's Hospital Medical Center Program (1988)
Residency Programs:
  • Cincinnati Children's Hospital Medical Center Program, Pediatrics (1990)
Fellowships:
  • Children's Hospital (Boston) Program, Pediatrics (1992)
Languages: English
Department: Pediatrics-Linda Crnic Institute for Down Syndrome
Contact Us
CU Anschutz
Fitzsimons Building

13001 East 17th Place
Campus Box C290
Aurora, CO 80045

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