Francis Hickey, MD, FAAP

Research Interests

Dr. Hickey has conducted many research projects related to exploring development in individuals with Down syndrome and autism and has authored or co-authored numerous articles and abstracts in scholarly publications on the topic.

Publications

• Advances in Pediatrics 59 (2012) 137–157 ADVANCES IN PEDIATRICS Medical Update for Children WithDown Syndrome for the Pediatrician and Family Practitioner Fran Hickey, MDa,*, Erin Hickeya, Karen L. Summar, MD, MSb
• When Down Syndrome and Autism Intersect A Guide to DS-ASD for Parents and Professionals By Margaret Froehlke & Robin Zaborek
• Jacola LM, Byars AW, Hickey F, Vannest J, Holland SK, Schapiro MB. Functional magnetic resonance imaging of story listening in adolescents and young adults with Down syndrome: evidence for atypical neurodevelopment. J Intellect Disabil Res. 2013 Aug 20. [Epub ahead of print] PubMed PMID: 23962356
• Jacola LM, Byars AW, Hickey F, Vannest J, Holland SK, Schapiro MB. Functional magnetic resonance imaging of story listening in adolescents and young adults with Down syndrome: evidence for atypical neurodevelopment. J Intellect Disabil Res. 2014 Oct;58(10):892-902. PubMed PMID: 23962356
• Citation: Associated Cardiac Findings in Children with Down Syndrome and Infantile Spasms Additional Information: Poster presentation at the American Epilepsy Society Meeting, Seattle, Washington December 2014 Type:
• Citation: Improved Outcome of Infantile Spasms in Down Syndrome Population Additional Information: Poster presentation at the Pediatric Academic Society Meeting, Vancouver, BC 5/2014
• Jacola LM, Byars AW, Hickey F, Vannest J, Holland SK, Schapiro MB. Functional magnetic resonance imaging of story listening in adolescents and young adults with Down syndrome: evidence for atypical neurodevelopment. J Intellect Disabil Res. 2014 Oct;58(10):892-902. PubMed PMID: 23962356
• Jackson A, Maybee J, Moran MK, Wolter-Warmerdam K, Hickey F. Clinical Characteristics of Dysphagia in Children with Down Syndrome. Dysphagia. 2016 Oct;31(5):663-71. PubMed PMID: 27405422
• Santoro SL, Esbensen AJ, Hopkin RJ, Hendershot L, Hickey F, Patterson B. Contributions to Racial Disparity in Mortality among Children with Down Syndrome. J Pediatr. 2016 Jul;174:240-246.e1. PubMed PMID: 27063805
• Other Type: Clinical Pathway Year of Publication: 2017 In-Press? yes First or Senior Author? False Citation: Clinical Pathway:Aspiration and Dysphagia in Children with Down Syndrome
• Nightengale E, Yoon P, Wolter-Warmerdam K, Daniels D, Hickey F. Understanding Hearing and Hearing Loss in Children With Down Syndrome. Am J Audiol. 2017 Sep 18;26(3):301-308. PubMed PMID: 28854301
• Sullivan KD, Evans D, Pandey A, Hraha TH, Smith KP, Markham N, Rachubinski AL, Wolter-Warmerdam K, Hickey F, Espinosa JM, Blumenthal T. Trisomy 21 causes changes in the circulating proteome indicative of chronic autoinflammation. Sci Rep. 2017 Nov 1;7(1):14818. PubMed PMID: 29093484
• Winders P, Wolter-Warmerdam K, Hickey F. A schedule of gross motor development for children with Down syndrome. J Intellect Disabil Res. 2018 Dec 21. [Epub ahead of print] PubMed PMID: 30575169
• Bush D, Galambos C, Ivy DD, Abman SH, Wolter-Warmerdam K, Hickey F. Clinical Characteristics and Risk Factors for Developing Pulmonary Hypertension in Children with Down Syndrome. J Pediatr. 2018 Nov;202:212-219.e2. PubMed PMID: 30025669
• Palat P, Hickey F, Patel L, Sannar E. Levodopa-Responsive Early-Onset Parkinsonism in Down Syndrome. Case Rep Neurol Med. 2018;2018:2314791. PubMed PMID: 29666730
• Goot BH, Kaufman J, Pan Z, Bourne DWA, Hickey F, Twite M, Galinkin J, Christians U, Zuk J, da Cruz EM. Morphine Pharmacokinetics in Children With Down Syndrome Following Cardiac Surgery. Pediatr Crit Care Med. 2018 May;19(5):459-467. PubMed PMID: 29547456
• Jackson A, Maybee J, Wolter-Warmerdam K, DeBoer E, Hickey F. Associations between age, respiratory comorbidities, and dysphagia in infants with down syndrome. Pediatr Pulmonol. 2019 Nov;54(11):1853-1859. PubMed PMID: 31402588
• Jackson A, Maybee J, Moran MK, Wolter-Warmerdam K, Hickey F. Clinical Characteristics of Dysphagia in Children with Down Syndrome. Dysphagia. 2016 Oct;31(5):663-71. PubMed PMID: 27405422
• Santoro SL, Esbensen AJ, Hopkin RJ, Hendershot L, Hickey F, Patterson B. Contributions to Racial Disparity in Mortality among Children with Down Syndrome. J Pediatr. 2016 Jul;174:240-246.e1. PubMed PMID: 27063805
• Citation: Liu, E., Wolter-Warmerdam, K., Marmolejo, J., Daniels, D., Prince, G., & Hickey, F. (2020). Routine Screening for Celiac Disease in Children With Down Syndrome Improves Case Finding. Journal of pediatric gastroenterology and nutrition, 71(2), 252-256.
• Citation: Nightengale, E. E., Wolter-Warmerdam, K., Yoon, P. J., Daniels, D., & Hickey, F. (2020). Behavioral Audiology Procedures in Children With Down Syndrome. American Journal of Audiology, 29(3), 356-364.
• Keratoconus and corneal morphology in patients with Down syndrome at a pediatric hospital. Imbornoni LM, Wise RE, Taravella MJ, Hickey F, McCourt EA. J AAPOS. 2020 Jun;24(3):140.e1-140.e5. doi: 10.1016/j.jaapos.2020.02.004. Epub 2020 May 27. PMID: 32473288
• Bush D, Wolter-Warmerdam K, Wagner BD, Galambos C, Ivy DD, Abman S, McMorrow D, Hickey F. EXPRESS: Angiogenic Profile Identifies Pulmonary Hypertension in Children with Down Syndrome. Pulm Circ. 2019 Jul 11;:2045894019866549. [Epub ahead of print] PubMed PMID: 31293212
• Ruiz AG, Gao D, Ingram DG, Hickey F, Haemer MA, Friedman NR. Does Tonsillectomy Increase Obesity Risk in Children with Down Syndrome?. J Pediatr. 2019 Aug;211:179-184.e1. PubMed PMID: 31084917
• Daniels D, Knupp K, Benke T, Wolter-Warmerdam K, Moran M, Hickey F. Infantile Spasms in Children With Down Syndrome: Identification and Treatment Response. Glob Pediatr Health. 2019;6:2333794X18821939. PubMed PMID: 30671494
• Winders P, Wolter-Warmerdam K, Hickey F. A schedule of gross motor development for children with Down syndrome. J Intellect Disabil Res. 2019 Apr;63(4):346-356. PubMed PMID: 30575169
• Araya P, Kinning KT, Coughlan C, Smith KP, Granrath RE, Enriquez-Estrada BA, Worek K, Sullivan KD, Rachubinski AL, Wolter-Warmerdam K, Hickey F, Galbraith MD, Potter H, Espinosa JM. IGF1 deficiency integrates stunted growth and neurodegeneration in Down syndrome. Cell Rep. 2022 Dec 27;41(13):111883. PubMed PMID: 36577365
• Barreiro A, Wolter-Warmerdam K, Friedman S, Hickey F, Johnson S, Marmolejo J. Child feeding practices in children with Down syndrome in relationship to ethnicity and BMI. Appetite. 2021 Dec 23;170:105888. [Epub ahead of print] PubMed PMID: 34953969
• Daniels D, Wolter-Warmerdam K, Holland S, Hickey F. Reach Out and Read Implementation in a Pediatric Down Syndrome Clinic. J Pediatr Health Care. 2021 Dec 5. [Epub ahead of print] PubMed PMID: 34879985
• Griffiths M, Yang J, Vaidya D, Nies M, Brandal S, Ivy DD, Hickey F, Wolter-Warmerdam K, Austin ED, Mullen M, Pauciulo MW, Lutz KA, Rosenzweig EB, Hirsch R, Yung D, Nichols WC, Everett AD. Biomarkers of Pulmonary Hypertension Are Altered in Children with Down Syndrome and Pulmonary Hypertension. J Pediatr. 2021 Oct 21. [Epub ahead of print] PubMed PMID: 34687693
• Vielkind ML, Hamlington KL, Wolter-Warmerdam K, Meier MR, Liu AH, Hickey FJ, Brown MA, DeBoer EM. Airwave oscillometry to measure lung function in children with Down syndrome. Pediatr Res. 2021 Jul 29. [Epub ahead of print] PubMed PMID: 34326475
• Vielkind M, Wolter-Warmerdam K, Jackson A, Maybee J, Brown M, Friedlander J, Friedman N, Hickey F, Prager J, Wine T, DeBoer E. Airway obstruction and inflammation on combined bronchoscopy in children with Down syndrome. Pediatr Pulmonol. 2021 Sep;56(9):2932-2939. PubMed PMID: 34245494
• Maybee J, Jackson A, Wolter-Warmerdam K, Hickey F, Prager J, DeBoer E. Validation of the Childhood Dysphagia Management Scale (CDMS): An Impact Scale for determining medical home for dysphagia. Int J Pediatr Otorhinolaryngol. 2021 Jun;145:110716. PubMed PMID: 33892340
• DeBoer EM, Wolter-Warmerdam K, Deterding RR, Marmolejo J, Blumenthal T, Espinosa JM, Hickey F, Wagner BD. Cardiopulmonary Phenotypes and Protein Signatures in Children With Down Syndrome. Clin Pediatr (Phila). 2023 Jun 12;:99228231179453. [Epub ahead of print] PubMed PMID: 37306037
• Araya P, Kinning KT, Coughlan C, Smith KP, Granrath RE, Enriquez-Estrada BA, Worek K, Sullivan KD, Rachubinski AL, Wolter-Warmerdam K, Hickey F, Galbraith MD, Potter H, Espinosa JM. IGF1 deficiency integrates stunted growth and neurodegeneration in Down syndrome. Cell Rep. 2022 Dec 27;41(13):111883. PubMed PMID: 36577365
• Harvey S, Wolter-Warmerdam K, Hickey F, Daniels D, DomBourian M, Ambruso DR, McKinney C. Blood counts in children with Down syndrome. Pediatr Blood Cancer. 2022 Dec;69(12):e30002. PubMed PMID: 36151966
• McCarthy S, Henderson K, Skinner C, Arreola LDS, Ng CJ, Jamil AN, Van de Voorde P, Cevik AA, von Schickfus M, Santos R, Jakubaszko J, Bognar Z, Baden D, Schmitz G, Pin MM, Beirne GJ, Kaji A, Løvstakken K, Siu A, Johnson K, Lim SHC, Tapia JDL, Ømark H, Moreno LA, Morphet J, Stebbeings S, Hickey F. Health-care workers and facilities in Ukraine must be protected. Lancet. 2022 Apr 2;399(10332):1299. PubMed PMID: 35338859
• Harvey S, Wolter-Warmerdam K, Hickey F, Daniels D, DomBourian M, Ambruso DR, McKinney C. Blood counts in children with Down syndrome. Pediatr Blood Cancer. 2022 Dec;69(12):e30002. PubMed PMID: 36151966
• Barreiro A, Wolter-Warmerdam K, Friedman S, Hickey F, Johnson S, Marmolejo J. Child feeding practices in children with Down syndrome in relationship to ethnicity and BMI. Appetite. 2022 Mar 1;170:105888. PubMed PMID: 34953969
• Barreiro A, Wolter-Warmerdam K, Friedman S, Hickey F, Johnson S, Marmolejo J. Child feeding practices in children with Down syndrome in relationship to ethnicity and BMI. Appetite. 2022 Mar 1;170:105888. PubMed PMID: 34953969
• Daniels D, Wolter-Warmerdam K, Holland S, Hickey F. Reach Out and Read Implementation in a Pediatric Down Syndrome Clinic. J Pediatr Health Care. 2022 May-Jun;36(3):231-239. PubMed PMID: 34879985
• Daniels D, Wolter-Warmerdam K, Holland S, Hickey F. Reach Out and Read Implementation in a Pediatric Down Syndrome Clinic. J Pediatr Health Care. 2022 May-Jun;36(3):231-239. PubMed PMID: 34879985
• Griffiths M, Yang J, Vaidya D, Nies M, Brandal S, Ivy DD, Hickey F, Wolter-Warmerdam K, Austin ED, Mullen M, Pauciulo MW, Lutz KA, Rosenzweig EB, Hirsch R, Yung D, Nichols WC, Everett AD. Biomarkers of Pulmonary Hypertension Are Altered in Children with Down Syndrome and Pulmonary Hypertension. J Pediatr. 2022 Feb;241:68-76.e3. PubMed PMID: 34687693
• Vielkind ML, Hamlington KL, Wolter-Warmerdam K, Meier MR, Liu AH, Hickey FJ, Brown MA, DeBoer EM. Airwave oscillometry to measure lung function in children with Down syndrome. Pediatr Res. 2022 Jun;91(7):1775-1780. PubMed PMID: 34326475
• Vielkind ML, Hamlington KL, Wolter-Warmerdam K, Meier MR, Liu AH, Hickey FJ, Brown MA, DeBoer EM. Airwave oscillometry to measure lung function in children with Down syndrome. Pediatr Res. 2022 Jun;91(7):1775-1780. PubMed PMID: 34326475
• Griffiths M, Yang J, Vaidya D, Nies M, Brandal S, Ivy DD, Hickey F, Wolter-Warmerdam K, Austin ED, Mullen M, Pauciulo MW, Lutz KA, Rosenzweig EB, Hirsch R, Yung D, Nichols WC, Everett AD. Biomarkers of Pulmonary Hypertension Are Altered in Children with Down Syndrome and Pulmonary Hypertension. J Pediatr. 2022 Feb;241:68-76.e3. PubMed PMID: 34687693

Practice Locations

Children's Hospital Colorado Anschutz Medical Campus
13123 East 16th Ave
Aurora, CO 80045
720-777-1234

Children's Hospital Colorado Child Health Clinic
860 N Potomac Cir
Aurora, CO 80011
720-777-2740

Hospital Affiliation

• Children's Hospital Colorado

Center Affiliations

• Colorado Fetal Care Center

Specialty Information

Specialties

• Pediatrics, Board Certification (2003)