Kathleen Simpson, MD

Professional Titles

• Associate Professor of Pediatrics, Pediatric Cardiology
• Director of Cardiomyopathy and Heart Failure

Publications

• Cochrane AB, Lyster H, Lindenfeld J, Doligalski C, Baran D, Yost C, Shullo M, Schweiger M, Weill D, Stuckey L, Ivulich S, Scheel J, Peters L, Colvin M, Dawson K, Girgis R, Weeks P, Tse T, Russell S, Flattery M, Jennings D, Kittleson M, Miller T, Khuu T, Claridge T, Uber P, Ford K, Ensor CR, Simpson K, Dipchand A, Page RL. Report from the 2018 consensus conference on immunomodulating agents in thoracic transplantation: Access, formulations, generics, therapeutic drug monitoring, and special populations. J Heart Lung Transplant. 2020;39(10):1050-1069.
• Simpson KE, Kirklin JK, Cantor RS, Mehegan M, Lamour JM, Guleserian KJ, Peng DM, Pahl E. Right heart failure with left ventricular assist device implantation in children: An analysis of the Pedimacs registry database. J Heart Lung Transplant. 2020 Mar;39(3):231-240. PubMed PMID: 31926747
• Godown J, Cantor R, Koehl D, Cummings E, Vo JB, Dodd DA, Lytrivi I, Boyle GJ, Sutcliffe DL, Kleinmahon JA, Shih R, Urschel S, Das B, Carlo WF, Zuckerman WA, West SC, McCulloch MA, Zinn, Simpson KE, Kindel SJ, Szmuszkovicz JR, Chrisant M, Auerbach SR, Carboni MP, Kirklin JK, Hsu DT. Practice variation in the diagnosis of acute rejection among pediatric heart transplant centers: An analysis of the pediatric heart transplant society (PHTS) registry. J Heart Lung Transplant. 2021 Aug 19. [Epub ahead of print] PubMed PMID: 34598871
• Gropler MRF, Lipshultz SE, Wilkinson JD, Towbin JA, Colan SD, Canter CE, Lavine KJ, Simpson KE. Pediatric and adult dilated cardiomyopathy are distinguished by distinct biomarker profiles. Pediatr Res. 2021 Aug 17. [Epub ahead of print] PubMed PMID: 34404929
• Lorts A, Conway J, Schweiger M, Adachi I, Amdani S, Auerbach SR, Barr C, Bleiweis MS, Blume ED, Burstein DS, Cedars A, Chen S, Cousino-Hood MK, Daly KP, Danziger-Isakov LA, Dubyk N, Eastaugh L, Friedland-Little J, Gajarski R, Hasan A, Hawkins B, Jeewa A, Kindel SJ, Kogaki S, Lantz J, Law SP, Maeda K, Mathew J, May LJ, Miera O, Murray J, Niebler RA, O'Connor MJ, Özbaran M, Peng DM, Philip J, Reardon LC, Rosenthal DN, Rossano J, Salazar L, Schumacher KR, Simpson KE, Stiller B, Sutcliffe DL, Tunuguntla H, VanderPluym C, Villa C, Wearden PD, Zafar F, Zimpfer D, Zinn MD, Morales IRD, Cowger J, Buchholz H, Amodeo A. ISHLT consensus statement for the selection and management of pediatric and congenital heart disease patients on ventricular assist devices Endorsed by the American Heart Association. J Heart Lung Transplant. 2021 Aug;40(8):709-732. PubMed PMID: 34193359
• Ybarra AM, Khanna G, Turmelle YP, Stoll J, Castleberry CD, Scheel J, Ballweg JA, Ameduri R, Kimberling M, Makil E, Birnbaum BF, Exil V, Canter CE, Simpson KE. Heterogeneous outcomes of liver disease after heart transplantation for a failed Fontan procedure. Pediatr Transplant. 2021 Jul 22;:e14094. [Epub ahead of print] PubMed PMID: 34296503
• Zafar F, Conway J, Bleiweis MS, Al-Aklabi M, Ameduri R, Barnes A, Bearl DW, Buchholz H, Church S, Do NL, Duffy V, Dykes JC, Eghtesady P, Fisher L, Friedland-Little J, Fuller S, Fynn-Thompson F, George K, Gossett JG, Griffiths ER, Griselli M, Hawkins B, Honjo O, Jeewa A, Joong A, Kindel S, Kouretas P, Lorts A, Machado D, Maeda K, Maurich A, May LJ, McConnell P, Mehegan M, Mongé M, Morales DLS, Murray J, Niebler RA, O'Connor M, Peng DM, Phelps C, Philip J, Ploutz M, Profsky M, Reichhold A, Rosenthal DN, Said AS, Schumacher KR, Si MS, Simpson KE, Sparks J, Louis JS, Steiner ME, VanderPluym C, Villa C. Berlin Heart EXCOR and ACTION post-approval surveillance study report. J Heart Lung Transplant. 2021 Apr;40(4):251-259. PubMed PMID: 33579597
• Law SP, Morales DLS, Si MS, Friedland-Little JM, Joong A, Bearl DW, Bansal N, Sutcliffe DL, Philip J, Mehegan M, Simpson KE, Conway J, Peng DM. Right heart failure considerations in pediatric ventricular assist devices. Pediatr Transplant. 2021 May;25(3):e13990. PubMed PMID: 33666316
• Auerbach SR, Simpson KE. HVAD Usage and Outcomes in the Current Pediatric Ventricular Assist Device Field: An Advanced Cardiac Therapies Improving Outcomes Network (ACTION) Analysis. ASAIO J. 2021 Jun 1;67(6):675-680. PubMed PMID: 33587465
• Nandi D, Aeurbach SR, Bansal N, Buchholz H, Cnway J, Esteso P, Kaufman BD, Lal AK, Law SP, Lorts A, May LJ, Mehegan M, Mokshagundam D, Morales DLS, O'Connor MJ, Rosentahl DN, Shezad MF, Simpson KE, Villa CR. Initial Multi-Center Experience with Ventricular Assist Devices in Children and Young Adults with Muscular Dystrophy: An ACTION Registry Analysis. JHLT 2022. epub Sept 20, 2022.
• Sagray E, Johnson JN, Schumacher KR, West S, Lowery RE, Simpson K. Protein-losing enteropathy recurrence after pediatric heart transplantation: Multicenter case series. Pediatr Transplant. 2022 Aug;26(5):e14295. PubMed PMID: 35451219
• Bogle C, Cantor R, Koehl D, Lochridge J, Kirklin JK, Barnes A, Wallis G, Amdani S, Ameduri R, Pahl E, Simpson KE, Blume ED. Obesity and dyslipidemia predict cardiac allograft vasculopathy and graft loss in children and adolescents post-heart transplant: A PHTS multi-institutional analysis. Pediatr Transplant. 2022 Aug;26(5):e14244. PubMed PMID: 35122464
• Simpson KE. The association of lymphopenia and post-transplant infection in children: is it time to change induction in Fontan heart transplant recipients? Pediatr Transplant. 2022 In press
• Ashfaq A, Lorts A, Rosenthal D, Adachi I, Rossano J, Davies R, Simpson KE, Maeda K, Wisotzkey B, Koehl D, Cantor RS, Jacobs JP, Peng D, Kirklin JK, Morales DLS. Survival in Pediatric Patients With Ventricular Assist Devices: A Special Pediatric Interagency Registry for Mechanical Circulatory Support (Pedimacs) Report. Ann Thorac Surg. 2023 Aug 11. [Epub ahead of print] PubMed PMID: 37573991
• Raval MV, Brockel MA, Kolacek S, Simpson KE, Spoede E, Starr KNP, Wulf KL. Key Strategies for Optimizing Pediatric Perioperative Nutrition-Insight from a Multidisciplinary Expert Panel. Nutrients. 2023 Mar 3;15(5). PubMed PMID: 36904269
• Adachi I, Peng DM, Hollander SA, Simpson KE, Davies RR, Jacobs JP, VanderPluym CJ, Fynn-Thompson F, Wells DA, Law SP, Amdani S, Cantor R, Koehl D, Kirklin JK, Morales DLS, Rossano JW. Sixth Annual Pediatric Interagency Registry for Mechanical Circulatory Support (Pedimacs) Report: The Society Of Thoracic Surgeons Pedimacs Annual Report. Ann Thorac Surg. 2023 May;115(5):1098-1108. PubMed PMID: 36402175
• Simpson KE. The association of lymphopenia and post-transplant infection in children: Is it time to change induction in Fontan heart transplant recipients?. Pediatr Transplant. 2023 Feb;27(1):e14420. PubMed PMID: 36303281
• Nandi D, Auerbach SR, Bansal N, Buchholz H, Conway J, Esteso P, Kaufman BD, Lal AK, Law SP, Lorts A, May LJ, Mehegan M, Mokshagundam D, Morales DLS, O'Connor MJ, Rosenthal DN, Shezad MF, Simpson KE, Sutcliffe DL, Vanderpluym C, Wittlieb-Weber CA, Zafar F, Cripe L, Villa CR. Initial multicenter experience with ventricular assist devices in children and young adults with muscular dystrophy: An ACTION registry analysis. J Heart Lung Transplant. 2023 Feb;42(2):246-254. PubMed PMID: 36270923
• Bogle C, Cantor R, Koehl D, Lochridge J, Kirklin JK, Barnes A, Wallis G, Amdani S, Ameduri R, Pahl E, Simpson KE, Blume ED. Obesity and dyslipidemia predict cardiac allograft vasculopathy and graft loss in children and adolescents post-heart transplant: A PHTS multi-institutional analysis. Pediatr Transplant. 2022 Aug;26(5):e14244. PubMed PMID: 35122464
• Amdani S, Simpson KE, Thrush P, Shih R, Simmonds J, Knecht K, Mogul DB, Hurley K, Koehl D, Cantor R, Naftel D, Kirklin JK, Daly KP. Hepatorenal dysfunction assessment with the Model for End-Stage Liver Disease Excluding INR score predicts worse survival after heart transplant in pediatric Fontan patients. J Thorac Cardiovasc Surg. 2022 Apr;163(4):1462-1473.e12. PubMed PMID: 33745714
• Gropler MRF, Lipshultz SE, Wilkinson JD, Towbin JA, Colan SD, Canter CE, Lavine KJ, Simpson KE. Pediatric and adult dilated cardiomyopathy are distinguished by distinct biomarker profiles. Pediatr Res. 2022 Jul;92(1):206-215. PubMed PMID: 34404929
• Peng DM, Davies RR, Simpson KE, Shugh SB, Morales DLS, Jacobs JP, Butto A, Joong A, Conway J, Schindler K, Griffiths ER, Koehl D, Cantor RS, Kirklin JK, Rossano JW, Adachi I. Seventh Annual Society of Thoracic Surgeons Pedimacs Report. Ann Thorac Surg. 2024 Apr;117(4):690-703. PubMed PMID: 38123046
• Chan M, Silveira L, Patterson DJ, Bock ME, Pietra BA, Everitt MD, Simpson KE, Miyamoto SD, Auerbach SR. Changes in estimated glomerular filtration rate over the first year following repeat heart transplant in children and young adults. Pediatr Transplant. 2024 Feb;28(1):e14651. PubMed PMID: 38015081
• Ashfaq A, Lorts A, Rosenthal D, Adachi I, Rossano J, Davies R, Simpson KE, Maeda K, Wisotzkey B, Koehl D, Cantor RS, Jacobs JP, Peng D, Kirklin JK, Morales DLS. Predicting Stroke for Pediatric Patients Supported With Ventricular Assist Devices: A Pedimacs Report. Ann Thorac Surg. 2024 Oct;118(4):889-897. PubMed PMID: 38802036

Practice Locations

Specialty Information

• Pediatrics, Board Certification
• Pediatric Cardiology, Board Certification
• Pediatric heart failure and transplantation advanced fellowship, Specialized Training (2013)

• Heart and Circulation - Cardiomyopathy
• Heart and Circulation
• Heart and Circulation - Congenital Heart Disease
• Heart and Circulation - Heart Failure
• Heart and Circulation - Cardio-oncology