Arleta Rewers, MD, PhD

Publications

• Ross DW, Rewers A, Homan MB, Schullek JR, Hawke JL, Hedegaard H. Factors associated with the interfacility transfer of the pediatric trauma patient: implications for prehospital triage. Pediatr Emerg Care. 2012 Sep;28(9):905-10. PubMed PMID: 22929144
• Bagdure D, Rewers A, Campagna E, Sills MR. Epidemiology of hyperglycemic hyperosmolar syndrome in children hospitalized in USA. Pediatr Diabetes. 2013 Feb;14(1):18-24. PubMed PMID: 22925225
• Rewers A. Current concepts and controversies in prevention and treatment of diabetic ketoacidosis in children. Curr Diab Rep. 2012 Oct;12(5):524-32. PubMed PMID: 22864672
• 23. A. Rewers, M. Rewers. ”Epidemic of DKA in Colorado: An indicator of childhood poverty and poor access to care” Poster presentation for the 48th EASD Annual Meeting, Berlin, 2012. Diabetologia, 2012; 55 (Suppl.1), S 140
• 24. D. Bagdure, A. Rewers, E. Campagna, M. Sills. Hyperosmolar hyperglycemic syndrome in children hospitalized in the United States. Poster presentation at the 38th Annual Meeting of the International Society for Pediatric & Adolescent Diabetes, Istanbul, Turkey. Pediatric Diabetes, 2012;13 (Suppl.17), p 96
• 22. Beck RW, Tamborlane WV, Bergenstal RM, Miller KM, DuBose SN, Hall CA; The T1D Exchange clinic registry.J Clin Endocrinol Metab. 2012 Dec;97(12):4383-9.
• Cengiz E, Xing D, Wong JC, Wolfsdorf JI, Haymond MW, Rewers A, Shanmugham S, Tamborlane WV, Willi SM, Seiple DL, Miller KM, Dubose SN, Beck RW; for the T1D Exchange Clinic Network.
• Cengiz E, Xing D, Wong JC, Wolfsdorf JI, Haymond MW, Rewers A, Shanmugham S, Tamborlane WV, Willi SM, Seiple DL, Miller KM, DuBose SN, Beck RW, T1D Exchange Clinic Network. Severe hypoglycemia and diabetic ketoacidosis among youth with type 1 diabetes in the T1D Exchange clinic registry. Pediatr Diabetes. 2013 Sep;14(6):447-54. PubMed PMID: 23469984
• Bagdure D, Rewers A, Campagna E, Sills MR. Epidemiology of hyperglycemic hyperosmolar syndrome in children hospitalized in USA. Pediatr Diabetes. 2013 Feb;14(1):18-24. PubMed PMID: 22925225
• Weinstock RS, Xing D, Maahs DM, Michels A, Rickels MR, Peters AL, Bergenstal RM, Harris B, Dubose SN, Miller KM, Beck RW, T1D Exchange Clinic Network. Severe hypoglycemia and diabetic ketoacidosis in adults with type 1 diabetes: results from the T1D Exchange clinic registry. J Clin Endocrinol Metab. 2013 Aug;98(8):3411-9. PubMed PMID: 23760624
• Wood JR, Miller KM, Maahs DM, Beck RW, DiMeglio LA, Libman IM, Quinn M, Tamborlane WV, Woerner SE, T1D Exchange Clinic Network. Most youth with type 1 diabetes in the T1D Exchange Clinic Registry do not meet American Diabetes Association or International Society for Pediatric and Adolescent Diabetes clinical guidelines. Diabetes Care. 2013 Jul;36(7):2035-7. PubMed PMID: 23340893
• Glaser NS, Ghetti S, Casper TC, Dean JM, Kuppermann N, Pediatric Emergency Care Applied Research Network (PECARN) DKA FLUID Study Group. Pediatric diabetic ketoacidosis, fluid therapy, and cerebral injury: the design of a factorial randomized controlled trial. Pediatr Diabetes. 2013 Sep;14(6):435-46. PubMed PMID: 23490311
• Ly TT, Maahs DM, Rewers A, Dunger D, Oduwole A, Jones TW. Assessment and management of hypoglycemia in children and adolescents with diabetes. Pediatr Diabetes. 2014 Sep;15 Suppl 20:180-92. PubMed PMID: 25040141
• Rewers A, Dong F, Slover RH, Klingensmith GJ, Rewers M. Incidence of diabetic ketoacidosis at diagnosis of type 1 diabetes in Colorado youth, 1998-2012. JAMA. 2015 Apr 21;313(15):1570-2. PubMed PMID: 25898057
• Dabelea D, Rewers A, Stafford JM, Standiford DA, Lawrence JM, Saydah S, Imperatore G, D'Agostino RB Jr, Mayer-Davis EJ, Pihoker C, SEARCH for Diabetes in Youth Study Group. Trends in the prevalence of ketoacidosis at diabetes diagnosis: the SEARCH for diabetes in youth study. Pediatrics. 2014 Apr;133(4):e938-45. PubMed PMID: 24685959
• DuBose SN, Hermann JM, Tamborlane WV, Beck RW, Dost A, DiMeglio LA, Schwab KO, Holl RW, Hofer SE, Maahs DM. Obesity in Youth with Type 1 Diabetes in Germany, Austria, and the United States. J Pediatr. 2015 Sep;167(3):627-32.e1-4. PubMed PMID: 26164381
• A Rewers; F Dong; R Slover; G Klingensmith; M Rewers "Prevalence of Diabetic Ketoacidosis at Diagnosis of Type 1 Diabetes in Youth in Colorado, 1998-2012.," MS #JAMA14-10245R
• Willi SM, Miller KM, DiMeglio LA, Klingensmith GJ, Simmons JH, Tamborlane WV, Nadeau KJ, Kittelsrud JM, Huckfeldt P, Beck RW, Lipman TH. Racial-ethnic disparities in management and outcomes among children with type 1 diabetes. Pediatrics. 2015 Mar;135(3):424-34. PubMed PMID: 25687140
• Poppy A, Retamal-Munoz C, Cree-Green M, Wood C, Davis S, Clements SA, Majidi S, Steck AK, Alonso GT, Chambers C, Rewers A. Reduction of Insulin Related Preventable Severe Hypoglycemic Events in Hospitalized Children. Pediatrics. 2016 Jul;138(1). PubMed PMID: 27317577
• Rewers A. Acute complications of diabetes. 3rd edition Diabetes in America
• A contrast between children and adolescents with excellent and poor control: the T1D Exchange clinic registry experience. Campbell MS1, Schatz DA, Chen V, Wong JC, Steck A, Tamborlane WV, Smith J, Beck RW, Cengiz E, Laffel LM, Miller KM, Haller MJ; T1D Exchange Clinic Network. Pediatr Diabetes. 2014 Mar;15(2):110-7. doi: 10.1111/pedi.12067. Epub 2013 Aug 19.
• Garro A, Chodobski A, Szmydynger-Chodobska J, Shan R, Bialo SR, Bennett J, Quayle K, Rewers A, Schunk JE, Casper TC, Kuppermann N, Glaser N. Circulating matrix metalloproteinases in children with diabetic ketoacidosis. Pediatr Diabetes. 2016 Feb 4. [Epub ahead of print] PubMed PMID: 26843101
• Bakes K, Haukoos JS, Deakyne SJ, Hopkins E, Easter J, McFann K, Brent A, Rewers A. Effect of Volume of Fluid Resuscitation on Metabolic Normalization in Children Presenting in Diabetic Ketoacidosis: A Randomized Controlled Trial. J Emerg Med. 2016 Apr;50(4):551-9. PubMed PMID: 26823137
• Duca LM, Wang B, Rewers M, Rewers A. Diabetic Ketoacidosis at Diagnosis of Type 1 Diabetes Predicts Poor Long-term Glycemic Control. Diabetes Care. 2017 Sep;40(9):1249-1255. PubMed PMID: 28667128
• A Rewers, S Babu, L Yu, F Dong, M Rewers; Effect of HLA-DR, DQ genotypes and family history of diabetes on the presence of diabetic ketoacidosis at diagnosis of type 1 diabetes in children. Pediatr Diabetes. 2014 Sep;15 Suppl 19:17.
• Garro A, Chodobski A, Szmydynger-Chodobska J, Shan R, Bialo SR, Bennett J, Quayle K, Rewers A, Schunk JE, Casper TC, Kuppermann N, Glaser N. Circulating matrix metalloproteinases in children with diabetic ketoacidosis. Pediatr Diabetes. 2017 Mar;18(2):95-102. PubMed PMID: 26843101
• Craig ME, Prinz N, Boyle CT, Campbell FM, Jones TW, Hofer SE, Simmons JH, Holman N, Tham E, Fröhlich-Reiterer E, DuBose S, Thornton H, King B, Maahs DM, Holl RW, Warner JT. Prevalence of Celiac Disease in 52,721 Youth With Type 1 Diabetes: International Comparison Across Three Continents. Diabetes Care. 2017 Aug;40(8):1034-1040. PubMed PMID: 28546222
• Rewers A: Acute metabolic complications in diabetes. Chapter 17 in Diabetes in America, 3rd ed. Cowie CC, Casagrande SS, Menke A, Cissell MA, Eberhardt MS, Meigs JB, Gregg EW, Knowler WC, Barrett-Connor E, Becker DJ, Brancati FL, Boyko EJ, Herman WH, Howard BV, Narayan KMV, Rewers M, Fradkin JE, Eds. Bethesda, MD, National Institutes of Health, NIH Pub No. 17-1468, 2017, p. 17.1–17.19
• Wolfsdorf JI, Glaser N, Agus M, Fritsch M, Hanas R, Rewers A, Sperling MA, Codner E. ISPAD Clinical Practice Consensus Guidelines 2018: Diabetic ketoacidosis and the hyperglycemic hyperosmolar state. Pediatr Diabetes. 2018 Oct;19 Suppl 27:155-177. PubMed PMID: 29900641
• Kuppermann N, Ghetti S, Schunk JE, Stoner MJ, Rewers A, McManemy JK, Myers SR, Nigrovic LE, Garro A, Brown KM, Quayle KS, Trainor JL, Tzimenatos L, Bennett JE, DePiero AD, Kwok MY, Perry CS 3rd, Olsen CS, Casper TC, Dean JM, Glaser NS. Clinical Trial of Fluid Infusion Rates for Pediatric Diabetic Ketoacidosis. N Engl J Med. 2018 Jun 14;378(24):2275-2287. PubMed PMID: 29897851
• A Rewers. Epidemiology of acute complications: diabetic ketoacidosis, hyperglycemic hyperosmolar state and hypoglycemia. In: Diabetes in America, 3rd ed. Cowie CC, Casagrande SS, Menke A, Cissell MA, Eberhardt MS, Meigs JB, Gregg EW, Knowler WC, Barrett-Connor E, Becker DJ, Brancati FL, Boyko EJ, Herman WH, Howard BV, Narayan KMV, Rewers M, Fradkin JE, Eds. Bethesda, MD, National Institutes of Health, NIH Pub No. 17-1468, 2018
• Duca LM, Reboussin BA, Pihoker C, Imperatore G, Saydah S, Mayer-Davis E, Rewers A, Dabelea D. Diabetic ketoacidosis at diagnosis of type 1 diabetes and glycemic control over time: The SEARCH for diabetes in youth study. Pediatr Diabetes. 2019 Mar;20(2):172-179. PubMed PMID: 30556249
• Alonso GT, Coakley A, Pyle L, Manseau K, Thomas S, Rewers A. Diabetic Ketoacidosis at Diagnosis of Type 1 Diabetes in Colorado Children, 2010-2017. Diabetes Care. 2019 Oct 10. [Epub ahead of print] PubMed PMID: 31601639
• Miller KM, Hermann J, Foster N, Hofer SE, Rickels MR, Danne T, Clements MA, Lilienthal E, Maahs DM, Holl RW. Longitudinal Changes in Continuous Glucose Monitoring Use Among Individuals With Type 1 Diabetes: International Comparison in the German and Austrian DPV and U.S. T1D Exchange Registries. Diabetes Care. 2019 Oct 31. [Epub ahead of print] PubMed PMID: 31672703
• ARLETA REWERS, NATHAN DAVIS KUPPERMANN, MICHAEL J. STONER, ARIS GARRO, KIMBERLY QUAYLE, JONATHAN E. BENNETT, SAGE MYERS, JULIE K. MCMANEMY, LISE E. NIGROVIC, JENNIFER L. TRAINOR, LEAH TZIMENATOS, MARIA KWOK, CODY S. OLSEN, THERON C. CASPER, SIMONA GHETTI and NICOLE GLASER Effects of Fluid Rehydration Strategy on Correction of Acidosis and Electrolyte Abnormalities in Children with Diabetic Ketoacidosis. Diabetes 2019 Jun; 68(Supplement 1): -. https://doi.org/10.2337/db19-214-OR
• GUY T. ALONSO, ALEXANDER COAKLEY, LAURA PYLE, KATHERINE MANSEAU, SARAH THOMAS, MARIAN REWERS and ARLETA REWERS Increase in Diabetic Ketoacidosis at Diagnosis of T1D in Colorado Children, 2010-2017 Diabetes 2019 Jun; 68(Supplement 1): -. https://doi.org/10.2337/db19-1360-P
• TRENDS IN DIABETIC KETOACIDOSIS AT DIAGNOSIS OF T1D IN COLORADO CHILDREN Rewers A, Coakley A, Pyle L, Manseau K, Thomas S, Alonso GT Diabetologia, Vol 63, Sep 1, Suppl 1, OR 115
• Rapid increase in prevalence of DKA at diagnosis among youth with type 1 diabetes: The SEARCH for Diabetes in Youth Study E T Jensen, JM Stafford, SSaydah, RB D'Agostino, Jr, LM Dolan, JM Lawrence, S Marcovina6, EJ Mayer-Davis, C Pihoker, A Rewers, D Dabelea Diabetologia, Vol 63, Sep 1, Suppl 1, OR 116
• Ghetti S, Kuppermann N, Rewers A, Myers SR, Schunk JE, Stoner MJ, Garro A, Quayle KS, Brown KM, Trainor JL, Tzimenatos L, DePiero AD, McManemy JK, Nigrovic LE, Kwok MY, Perry CS 3rd, Olsen CS, Casper TC, Glaser NS. Cognitive Function Following Diabetic Ketoacidosis in Children With New-Onset or Previously Diagnosed Type 1 Diabetes. Diabetes Care. 2020 Nov;43(11):2768-2775. PubMed PMID: 32962981
• DePiero A, Kuppermann N, Brown KM, Schunk JE, McManemy JK, Rewers A, Stoner MJ, Tzimenatos L, Garro A, Myers SR, Quayle KS, Trainor JL, Kwok MY, Nigrovic LE, Olsen CS, Casper TC, Ghetti S, Glaser NS. Hypertension during Diabetic Ketoacidosis in Children. J Pediatr. 2020 Aug;223:156-163.e5. PubMed PMID: 32387716
• Alonso GT, Coakley A, Pyle L, Manseau K, Thomas S, Rewers A. Diabetic Ketoacidosis at Diagnosis of Type 1 Diabetes in Colorado Children, 2010-2017. Diabetes Care. 2020 Jan;43(1):117-121. PubMed PMID: 31601639
• Myers S, Glaser N, Trainor J, Nigrovic L, Garro A, Tzimenatos L, Quayle KS, Kwok M, Rewers A, Stoner MJ, Schunk JE, McManemy JK, Brown KM, DePiero A, Olsen C, Casper TC, Ghetti S, Kuppermann N for the PECARN DKA FLUID Study Group. Frequency, Risk Factors and Associations of Acute Kidney Injury During Diabetic Ketoacidosis in Children. JAMA OPEN (in press)
• Miller KM, Hermann J, Foster N, et al. Longitudinal Changes in Continuous Glucose Monitoring Use Among Individuals With Type 1 Diabetes: International Comparison in the German and Austrian DPV and U.S. T1D Exchange Registries. Diabetes Care. 2020 Jan;43(1):e1-e2. PMID: 31672703
• Mizokami-Stout KR, Li Z, Foster NC, et al for T1D Exchange Clinic Network. The Contemporary Prevalence of Diabetic Neuropathy in Type 1 Diabetes: Findings From the T1D Exchange. Diabetes Care. 2020 Apr;43(4):806-812. PMID: 32029635
• Piani F, Melena I, Severn C, Chung LT, Vinovskis C, Cherney D, Pyle L, Roncal-Jimenez CA, Lanaspa MA, Rewers A, van Raalte DH, Obeid W, Parikh C, Nelson RG, Pavkov ME, Nadeau KJ, Johnson RJ, Bjornstad P. Tubular injury in diabetic ketoacidosis: Results from the diabetic kidney alarm study. Pediatr Diabetes. 2021 Nov;22(7):1031-1039. PubMed PMID: 34435718
• Glaser NS, Stoner MJ, Garro A, Baird S, Myers SR, Rewers A, Brown KM, Trainor JL, Quayle KS, McManemy JK, DePiero AD, Nigrovic LE, Tzimenatos L, Schunk JE, Olsen CS, Casper TC, Ghetti S, Kuppermann N. Serum Sodium Concentration and Mental Status in Children With Diabetic Ketoacidosis. Pediatrics. 2021 Sep;148(3). PubMed PMID: 34373322
• Rewers A, Kuppermann N, Stoner MJ, Garro A, Bennett JE, Quayle KS, Schunk JE, Myers SR, McManemy JK, Nigrovic LE, Trainor JL, Tzimenatos L, Kwok MY, Brown KM, Olsen CS, Casper TC, Ghetti S, Glaser NS. Effects of Fluid Rehydration Strategy on Correction of Acidosis and Electrolyte Abnormalities in Children With Diabetic Ketoacidosis. Diabetes Care. 2021 Sep;44(9):2061-2068. PubMed PMID: 34187840
• Jensen ET, Stafford JM, Saydah S, D'Agostino RB, Dolan LM, Lawrence JM, Marcovina S, Mayer-Davis EJ, Pihoker C, Rewers A, Dabelea D. Increase in Prevalence of Diabetic Ketoacidosis at Diagnosis Among Youth With Type 1 Diabetes: The SEARCH for Diabetes in Youth Study. Diabetes Care. 2021 Jul;44(7):1573-1578. PubMed PMID: 34099516
• Alonso GT, Murphy C, Pyle L, Thomas S, Ohman-Hanson R, Rewers A. Increased Prevalence of Diabetic Ketoacidosis Among Colorado Children at Diagnosis of Type 1 Diabetes During the COVID-19 Pandemic Lockdown Resolves After Reopening. Diabetes Technol Ther. 2021 Sep;23(9):663-664. PubMed PMID: 33835859
• Glaser N, Fritsch M, Priyambada L, Rewers A, Cherubini V, Estrada S, Wolfsdorf JI, Codner E. ISPAD clinical practice consensus guidelines 2022: Diabetic ketoacidosis and hyperglycemic hyperosmolar state. Pediatr Diabetes. 2022 Nov;23(7):835-856. PubMed PMID: 36250645
• Birkebaek NH, Kamrath C, Grimsmann JM, Aakesson K, Cherubini V, Dovc K, de Beaufort C, Alonso GT, Gregory JW, White M, Skrivarhaug T, Sumnik Z, Jefferies C, Hörtenhuber T, Haynes A, De Bock M, Svensson J, Warner JT, Gani O, Gesuita R, Schiaffini R, Hanas R, Rewers A, Eckert AJ, Holl RW, Cinek O. Impact of the COVID-19 pandemic on long-term trends in the prevalence of diabetic ketoacidosis at diagnosis of paediatric type 1 diabetes: an international multicentre study based on data from 13 national diabetes registries. Lancet Diabetes Endocrinol. 2022 Nov;10(11):786-794. PubMed PMID: 36202118
• Glaser NS, Quayle KS, McManemy JK, Nigrovic LE, Tzimenatos L, Stoner MJ, Bennett JE, Trainor JL, Rewers A, Schunk JE, Myers SR, Kwok MY, Brown KM, Ghetti S, Casper TC, Olsen CS, Kuppermann N. Clinical Characteristics of Children with Cerebral Injury preceding Treatment of Diabetic Ketoacidosis. J Pediatr. 2022 Nov;250:100-104. PubMed PMID: 35944716
• Melena I, Piani F, Tommerdahl KL, Severn C, Chung LT, MacDonald A, Vinovskis C, Cherney D, Pyle L, Roncal-Jimenez CA, Lanaspa MA, Rewers A, van Raalte DH, Cara-Fuentes G, Parikh CR, Nelson RG, Pavkov ME, Nadeau KJ, Johnson RJ, Bjornstad P. Aminoaciduria and metabolic dysregulation during diabetic ketoacidosis: Results from the diabetic kidney alarm (DKA) study. J Diabetes Complications. 2022 Jun;36(6):108203. PubMed PMID: 35523653
• Brown KM, Glaser NS, McManemy JK, DePiero A, Nigrovic LE, Quayle KS, Stoner MJ, Schunk JE, Trainor JL, Tzimenatos L, Rewers A, Myers SR, Kwok MY, Ghetti S, Casper TC, Olsen CS, Kuppermann N. Rehydration Rates and Outcomes in Overweight Children With Diabetic Ketoacidosis. Pediatrics. 2023 Dec 1;152(6). PubMed PMID: 37920947
• Cai LY, Tanase C, Anderson AW, Patel NJ, Lee CA, Jones RS, LeStourgeon LM, Mahon A, Taki I, Juvera J, Pruthi S, Gwal K, Ozturk A, Kang H, Rewers A, Rewers MJ, Alonso GT, Glaser N, Ghetti S, Jaser SS, Landman BA, Jordan LC. Exploratory Multisite MR Spectroscopic Imaging Shows White Matter Neuroaxonal Loss Associated with Complications of Type 1 Diabetes in Children. AJNR Am J Neuroradiol. 2023 Jul;44(7):820-827. PubMed PMID: 37263786
• Trainor JL, Glaser NS, Tzimenatos L, Stoner MJ, Brown KM, McManemy JK, Schunk JE, Quayle KS, Nigrovic LE, Rewers A, Myers SR, Bennett JE, Kwok MY, Olsen CS, Casper TC, Ghetti S, Kuppermann N. Clinical and Laboratory Predictors of Dehydration Severity in Children With Diabetic Ketoacidosis. Ann Emerg Med. 2023 Aug;82(2):167-178. PubMed PMID: 37024382
• Ghetti S, Kuppermann N, Rewers A, Myers SR, Schunk JE, Stoner MJ, Garro A, Quayle KS, Brown KM, Trainor JL, Tzimenatos L, DePiero AD, McManemy JK, Nigrovic LE, Kwok MY, Olsen CS, Casper TC, Glaser NS. Cognitive function following diabetic ketoacidosis in young children with type 1 diabetes. Endocrinol Diabetes Metab. 2023 May;6(3):e412. PubMed PMID: 36788736
• Glaser NS, Stoner MJ, Kwok MY, Quayle KS, Brown KM, Schunk JE, Trainor JL, McManemy JK, Tzimenatos L, Rewers A, Nigrovic LE, Bennett JE, Myers SR, Smith M, Casper TC, Kuppermann N. Relationships among biochemical measures in children with diabetic ketoacidosis. J Pediatr Endocrinol Metab. 2023 Mar 28;36(3):313-318. PubMed PMID: 36637392
• Sooy MGQ, Pyle L, Alonso GT, Broncucia HC, Rewers A, Gottlieb PA, Simmons KMW, Rewers MJ, Steck AK. Lower Prevalence of Diabetic Ketoacidosis at Diagnosis in Research Participants Monitored for Hyperglycemia. J Clin Endocrinol Metab. 2024 Mar 12. [Epub ahead of print] PubMed PMID: 38470864

Practice Locations

• Children's Hospital Colorado

Specialty Information

• Pediatric Emergency Medicine, Board Certification
• Pediatrics, Board Certification

• Emergency Care