Joshua Seinfeld, MD

Professional Titles

• Director of Endovascular Neurosurgery

Research Interests

My research interests are primarily clinical and relate to the study of patients that have suffered from brain aneurysms, vascular malformations or strokes. Specifically, I am developing medical devices and software to be utilized in the treatment of bleeding in and around the brain.

Publications

• Kumpe D, Bennett J, Seinfeld J, Pelak V, Chawla A, Tierney M: Dural sinus stent placment for idiopathic intracranial hypertension. Journal of Neurosurgery 2012 (116(3)
• Stence N, Colantoni W, Fenton L Kumpe D, Sinfeld J, Bernard T: Recurrent stroke in children with dissecting aneurysms of the vertebral artery: failure of antithrombotic therapies. Society of Pediatric Radiology. 2012 annual meeting San Francisco, Ca
• Kumpe D, Seinfeld J, Morrow J: Intracranial stenting for pseudotumor - results in 20 patients. Society of Interventional Radiology 2011 Annual Meeting. Chicago, Il
• Pelak V, Kaur P, Seinfeld J: Acute elevated intracranial pressure (ICP) syndrome associated with unilateral transverse/sigmoid dural vein thrombosis with rapid resolution following clot lysis by tpa, angiojet and balloon angioplasty. North American Neuro-Ophthamology Society Meeting 2011 Annual Meeting. Vancouver, BC
• Acute Posterior Multifocal Placoid Pigment Epitheliopathy associated with Stroke: A case report and review of the literature" by Case, David; Seinfeld, Joshua; Folzenlogen, Zach; Simpson, Jennifer; Jones, William; Hughes, Richard,
• Case D, Seinfeld J, Folzenlogen Z, Kumpe D: Anomalous Right Vertebral Artery Originating from the Aortic Arch Distal to the Left Subclavian Artery: a Case Report and Review of the Literature. Journal of Vascular and Interventional Neurology 8 (3,) 2015 PMID: 26301027
• Case D, Seinfeld J, Kumpe D, Folzenlogen Z, Jones W, Simpson J, Hughes R: Acute Posterior Multifocal Placoid Pigment Epitheliopathy Associated with Stroke: A Case Report and Review of the Literature. Journal of Stroke and Cerebrovascular Disease 6, 2015 PMID: 26277292
• Kumpe DA, Seinfeld J, Huang X, Mei Q, Case DE, Roark CD, Subramanian PS, Lind KE, Pelak VS, Bennett JL. Dural sinus stenting for idiopathic intracranial hypertension: factors associated with hemodynamic failure and management with extended stenting. J Neurointerv Surg. 2016 Nov 8. [Epub ahead of print] PubMed PMID: 27935482
• Case D, Kumpe D, Cava L, Neumann R, White A, Roark C, Seinfeld J. Ruptured Distal Posterior Inferior Cerebellar Artery (PICA) Aneurysms Associated with Cerebellar Arterial Venous Malformations (AVMs): A Case Series and Review of the Literature Demonstrating the Need for Angiographic Evaluation and Feasibility of Endovascular Treatment. World Neurosurg. 2016 Oct 25. [Epub ahead of print] PubMed PMID: 27793767
• Harland TA, Seinfeld J, Cava LF, Neumann RT, Roark C, Kumpe D, Case D. Anti-neutrophil cytoplasmic antibody associated central nervous system vasculitis with brain and spinal cord subarachnoid hemorrhage: A rare case report and review of the literature. J Clin Neurosci. 2018 Dec 26. [Epub ahead of print] PubMed PMID: 30594448
• Roark C, Case D, Gritz M, Hosokawa P, Kumpe D, Seinfeld J, Williamson CA, Libby AM. Nationwide analysis of hospital-to-hospital transfer in patients with aneurysmal subarachnoid hemorrhage requiring aneurysm repair. J Neurosurg. 2018 Oct 1;:1-8. [Epub ahead of print] PubMed PMID: 30497228
• White AC, Kumpe DA, Roark CD, Case DE, Seinfeld J. Patterns, Predictors, and Outcomes of Postprocedure Delayed Hemorrhage Following Flow Diversion for Intracranial Aneurysm Treatment. World Neurosurg. 2018 Jul;115:e97-e104. PubMed PMID: 29626682
• Seinfeld J, Karim S. Aneurysm, Cavernous Sinus. . 2018 Jan. PubMed PMID: 28613590
• Roark C, Vadlamudi V, Chaudhary N, Gemmete JJ, Seinfeld J, Thompson BG, Pandey AS. ABC/2 Method Does not Accurately Predict Cerebral Arteriovenous Malformation Volume. Neurosurgery. 2018 Feb 1;82(2):220-225. PubMed PMID: 28605551
• White AC, Folzenlogen ZA, Harland TA, Case DE, Roark CD, Kumpe DA, Seinfeld J. Intraosseous Cannulation of a Calvarial Diploic Vein for Embolization of a Symptomatic Dural Arteriovenous Fistula: A Technical Case Report. Oper Neurosurg (Hagerstown). 2019 Jun 27. [Epub ahead of print] PubMed PMID: 31245820
• Folzenlogen Z, Seinfeld J, Kubes S, Kumpe D, Case D, Roark C. Use of the PulseRider Device in the Treatment of Ruptured Intracranial Aneurysms: A Case Series. World Neurosurg. 2019 Jul;127:e149-e154. PubMed PMID: 30862588
• Harland TA, Seinfeld J, Cava LF, Neumann RT, Roark C, Kumpe D, Case D. Anti-neutrophil cytoplasmic antibody associated central nervous system vasculitis with brain and spinal cord subarachnoid hemorrhage: A rare case report and review of the literature. J Clin Neurosci. 2019 Apr;62:253-255. PubMed PMID: 30594448
• Seinfeld J, Karim S. Cavernous Sinus Aneurysm. . 2020 Jan. PubMed PMID: 28613590
• 33. Case D, Kumpe D, Roark C, Seinfeld J. Neuroangiography: review of anatomy, periprocedural management, technique and tips. Seminars in Interventional Radiology 2019
• 32. Case D, Seinfeld J, Roark C, Kumpe D. Idionpathic intracranial hypertension: contemporary management, patient selection, and endovascular technique. Seminars in Interventional Radiology 2019
• 3. Seinfeld J, Rogers RK, Casserly I: Carotid and Cerebrovascular Intervention. Textbook of Interventional Cardiology 8th ed. 2019
• White AC, Folzenlogen ZA, Harland TA, Case DE, Roark CD, Kumpe DA, Seinfeld J. Intraosseous Cannulation of a Calvarial Diploic Vein for Embolization of a Symptomatic Dural Arteriovenous Fistula: A Technical Case Report. Oper Neurosurg (Hagerstown). 2020 Apr 1;18(4):E132-E137. PubMed PMID: 31245820
• Seinfeld J, Karim S. Cavernous Sinus Aneurysm. . 2020 Jan. PubMed PMID: 28613590
• Harland TA, Seinfeld J, White AC, Kumpe DA, Roark CD, Case DE. Comparative Analysis of Unruptured Cerebral Aneurysm Treatment Outcomes and Complications with the Classic versus Flex Pipeline Embolization Devices and Phenom versus Marksman Microcatheter Delivery System: The Role of Microcatheter Choice on Complication Rate. J Vasc Interv Neurol. 2020 Jan;11(1):13-18. PubMed PMID: 32071667
• Randhawa PS, Roark C, Case D, Seinfeld J. Idiopathic Spinal Cord Herniation Associated With a Thoracic Disc Herniation: Case Report, Surgical Video, and Literature Review. Clin Spine Surg. 2020 Jul;33(6):222-229. PubMed PMID: 32101990
• Case D, Kumpe D, Roark C, Seinfeld J. Neuroangiography: Review of Anatomy, Periprocedural Management, Technique, and Tips. Semin Intervent Radiol. 2020 Jun;37(2):166-174. PubMed PMID: 32419729
• Case D, Seinfeld J, Roark C, Kumpe D. Idiopathic Intracranial Hypertension: Contemporary Management and Endovascular Techniques. Semin Intervent Radiol. 2020 Jun;37(2):175-181. PubMed PMID: 32419730
• Ung TH, Delcont MR, Colakoglu S, Seinfeld J, French B, Wilkinson CC. Reconstruction of Complex Scalp Defect After Cirsoid Aneurysm Resection: A Multidisciplinary Approach. World Neurosurg. 2020 Nov;143:190-196. PubMed PMID: 32745652
• Vranic JE, Harker P, Stapleton CJ, Regenhardt RW, Dmytriw AA, Alotaibi NM, Gupta R, Leslie-Mazwi TM, Koch MJ, Raymond SB, Mascitelli JR, Patterson TT, Seinfeld J, White A, Case D, Roark C, Gandhi CD, Al-Mufti F, Cooper J, Patel AB. Determinants of intracranial aneurysm retreatment following embolization with a single flow-diverting stent. Neuroradiol J. 2021 Nov 7;:19714009211049086. [Epub ahead of print] PubMed PMID: 34747246
• Morel BC, Barry M, Hoffman JE, Seinfeld J, Folzenlogen Z, Roark C, Case DE. Direct Carotid Artery Puncture for Thrombectomy in Pediatric Stroke. J Vasc Interv Radiol. 2021 Jun;32(6):921-923. PubMed PMID: 33677118
• Meyers PM, Fifi JT, Cockroft KM, Miller TR, Given CA, Zomorodi AR, Jagadeesan BD, Mokin M, Kan P, Yao TL, Diaz O, Huddle D, Bellon RJ, Seinfeld J, Polifka AJ, Fiorella D, Chitale RV, Kvamme P, Morrow JT, Singer J, Wakhloo AK, Puri AS, Deshmukh VR, Hanel RA, Gonzalez LF, Woo HH, Aziz-Sultan MA. Safety of the APOLLO Onyx delivery microcatheter for embolization of brain arteriovenous malformations: results from a prospective post-market study. J Neurointerv Surg. 2021 Oct;13(10):935-941. PubMed PMID: 33526480
• Seinfeld J, Karim S. Cavernous Sinus Aneurysm. . 2022 Jan. PubMed PMID: 28613590
• White A, Roark C, Case D, Folzenlogen Z, Kumpe D, Seinfeld J. Endovascular Management of Traumatic Intracranial Aneurysms From Closed Head Injury. Journal of Neurointerventional Surgery Vol 13(1) 2021
• Baker CM, Hunsaker JC, Folzenlogen ZA, Pride GL, Case DE, Welch BG, White JA, Roark CD, White AC, Seinfeld J, Muse J, Grandhi R, Taussky P. Technical Nuances and Outcomes of Telescoping Pipeline Flow Diverters: A Multicenter Study. Oper Neurosurg (Hagerstown). 2023 Jan 16. [Epub ahead of print] PubMed PMID: 36719956
• Morel BC, Wittenberg B, Hoffman JE, Case DE, Folzenlogen Z, Roark C, Seinfeld J. Untangling the Modern Treatment Paradigm for Unruptured Brain Arteriovenous Malformations. J Pers Med. 2022 May 30;12(6). PubMed PMID: 35743688
• Hoffman JE, Wittenberg B, Morel B, Folzenlogen Z, Case D, Roark C, Youssef S, Seinfeld J. Tailored Treatment Options for Cerebral Cavernous Malformations. J Pers Med. 2022 May 20;12(5). PubMed PMID: 35629253
• Ritchey Z, Bernard TJ, Fenton LZ, Maloney JA, Mirsky DM, Neuberger I, Sriram I, Seinfeld J, Stence NV. Stroke Recurrence in Children with Vertebral Artery Dissecting Aneurysm. AJNR Am J Neuroradiol. 2022 Jun;43(6):913-918. PubMed PMID: 35550284
• Seinfeld J, Karim S. Cavernous Sinus Aneurysm. . 2022 Jan. PubMed PMID: 28613590
• Vranic JE, Harker P, Stapleton CJ, Regenhardt RW, Dmytriw AA, Doron OM, Alotaibi NM, Leslie-Mazwi TM, Gupta R, Berglar IK, Tan CO, Koch MJ, Raymond SB, Mascitelli JR, Patterson TT, Seinfeld J, White A, Case D, Roark C, Gandhi CD, Al-Mufti F, Cooper J, Matouk C, Sujijantarat N, Devia DA, Ocampo-Navia MI, Villamizar-Torres DE, Puentes JC, Patel AB. The Impact of Dual Antiplatelet Therapy Duration on Unruptured Aneurysm Occlusion After Flow Diversion: A Multicenter Study. J Comput Assist Tomogr. 2023 Sep-Oct 01;47(5):753-758. PubMed PMID: 37707405
• Bounajem MT, Joyce E, Scoville JP, Seinfeld J, Hoffman J, Grossberg JA, Waiters V, White AC, Nerva J, Burkhardt JK, Tonetti DA, El Naamani K, Gooch MR, Jabbour P, Tjoumakaris S, Ortega Gutierrez S, Levitt MR, Lang M, Ares WJ, Desai S, Mascitelli JR, Kilburg CJ, Budohoski KP, Couldwell WT, Gross BA, Grandhi R. Safety and efficacy of the Pipeline Flex embolization device with Shield Technology for the acute treatment of ruptured internal carotid artery pseudoaneurysms: a multi-institution case series. Neurosurg Focus. 2023 May;54(5):E4. PubMed PMID: 37127036
• Callen AL, Timpone VM, Schwertner A, Zander D, Grassia F, Lennarson P, Seinfeld J, Lillehei KO, Birlea M, Thaker AA. Algorithmic Multimodality Approach to Diagnosis and Treatment of Spinal CSF Leak and Venous Fistula in Patients With Spontaneous Intracranial Hypotension. AJR Am J Roentgenol. 2022 Aug;219(2):292-301. PubMed PMID: 35261281
• Seinfeld J, Karim S. Cavernous Sinus Aneurysm. . 2024 Jan. PubMed PMID: 28613590
• Baker CM, Hunsaker JC, Folzenlogen ZA, Pride GL, Case DE, Welch BG, White JA, Roark CD, White AC, Seinfeld J, Muse J, Grandhi R, Taussky P. Technical Nuances and Outcomes of Telescoping Pipeline Flow Diverters: A Multicenter Study. Oper Neurosurg (Hagerstown). 2023 Apr 1;24(4):e255-e263. PubMed PMID: 36719956
• Vranic JE, Harker P, Stapleton CJ, Regenhardt RW, Dmytriw AA, Alotaibi NM, Gupta R, Leslie-Mazwi TM, Koch MJ, Raymond SB, Mascitelli JR, Patterson TT, Seinfeld J, White A, Case D, Roark C, Gandhi CD, Al-Mufti F, Cooper J, Patel AB. Determinants of intracranial aneurysm retreatment following embolization with a single flow-diverting stent. Neuroradiol J. 2022 Aug;35(4):461-467. PubMed PMID: 34747246
• Vranic, Justin E. MD*,†; Harker, Pablo MD‡; Stapleton, Christopher J. MD†; Regenhardt, Robert W. MD, PhD†; Dmytriw, Adam A. MD, MPH, MSc†,§; Doron, Omer M. MD, PhD†; Alotaibi, Naif M. MD?; Leslie-Mazwi, Thabele M. MD¶; Gupta, Rajiv MD, PhD*; Berglar, Inka K. Dipl-Math*; Tan, Can Ozan PhD*,**; Koch, Matthew J. MD††; Raymond, Scott B. MD, PhD‡‡; Mascitelli, Justin R. MD§§; Patterson, T. Tyler MD§§; Seinfeld, Joshua MD??; White, Andrew DO??; Case, David MD??; Roark, Christopher MD??; Gandhi, Chirag D. MD¶¶; Al-Mufti, Fawaz MD¶¶,***; Cooper, Jared MD¶¶; Matouk, Charles MD†††; Sujijantarat, Nanthiya MD†††; Devia, Diego A. MD‡‡‡; Ocampo-Navia, Maria I.‡‡‡; Villamizar-Torres, Daniel E.‡‡‡; Puentes, Juan C. MD‡‡‡§§§; Patel, Aman B. MD†. The Impact of Dual Antiplatelet Therapy Duration on Unruptured Aneurysm Occlusion After Flow Diversion: A Multicenter Study. Journal of Computer Assisted Tomography 47(5):p 753-758, 9/10 2023. | DOI: 10.1097/RCT.0000000000001457
• Sethi, A., Chee, K., Chatain, G. P., Wittenberg, B., Seinfeld, J., Milgrom, S., ... & Breeze, R. (2023). Time-Dosed Stereotactic Radiosurgery for the Treatment of Cerebral Arteriovenous Malformations: An Early Institution Experience and Case Series. Neurosurgery Practice, 4(4), e00060.

Professional Memberships

• Congress of Neurological Surgeons, Active Member
• American Association of Neurological Surgeons, Active Member
• Society of Neurointerventional Surgery, Active Member

Practice Locations

UCHealth Stroke and Brain Aneurysm Center - Anschutz Medical Campus
12401 E 17th Ave
Leprino Building, 3rd floor
Aurora, CO 80045
720-848-2080

UCHealth Neurosciences Center - Anschutz Medical Campus
1635 Aurora Ct
4th Floor
Aurora, CO 80045
720-848-2080

Rocky Mountain Gamma Knife Center - Anschutz Medical Campus
1635 Aurora Ct
Aurora, CO 80045
720-848-1290

Hospital Affiliation

• University of Colorado Hospital
• Children's Hospital Colorado
• Denver Health Medical Center

Specialty Information

Specialties

• Neurological Surgery, Board Certification (2012)
• Neurocritical Care - United Council for Neurologic Subspecialties, Board Certification (2013)
• Recognition of Focused Practice in Neuroendovascular Surgery, Focused Practice Designation (2023)

Conditions & Treatments

• Radiology - Neuroradiology
• Brain and Nervous System - Neurovascular Conditions
• Brain and Nervous System - Spine Diseases and Conditions
• Brain and Nervous System - Stroke
• Brain and Nervous System
• Brain and Nervous System - Brain Tumors
• Brain and Nervous System - Brain Abscess
• Brain and Nervous System - Chiari Malformation
• Brain and Nervous System - General Neurosurgery
• Brain and Nervous System - Hydrocephalus
• Brain and Nervous System - Trigeminal Neuralgia
• Brain and Nervous System - Traumatic and Acquired Brain Injuries
• Radiology