Hanan Elajaili, PhD

Publications

• Joshi M, Kim J, D'Alessandro A, Monk E, Bruce K, Elajaili H, Nozik-Grayck E, Goodspeed A, Costello JC, Schlaepfer IR. CPT1A Over-Expression Increases Reactive Oxygen Species in the Mitochondria and Promotes Antioxidant Defenses in Prostate Cancer. Cancers (Basel). 2020 Nov 18;12(11). PubMed PMID: 33218188
• Keller A, Hull SE, Elajaili H, Johnston A, Knaub LA, Chun JH, Walker L, Nozik-Grayck E, Reusch JEB. (-)-Epicatechin Modulates Mitochondrial Redox in Vascular Cell Models of Oxidative Stress. Oxid Med Cell Longev. 2020;2020:6392629. PubMed PMID: 32587663
• Tseng V, Ni K, Allawzi A, Prohaska C, Hernandez-Lagunas L, Elajaili H, Cali V, Midura R, Hascall V, Triggs-Raine B, Petrache I, Hart CM, Nozik-Grayck E. Extracellular Superoxide Dismutase Regulates Early Vascular Hyaluronan Remodeling in Hypoxic Pulmonary Hypertension. Sci Rep. 2020 Jan 14;10(1):280. PubMed PMID: 31937874
• Vohwinkel CU, Coit EJ, Burns N, Elajaili H, Hernandez-Saavedra D, Yuan X, Eckle T, Nozik E, Tuder RM, Eltzschig HK. Targeting alveolar-specific succinate dehydrogenase A attenuates pulmonary inflammation during acute lung injury. FASEB J. 2021 Apr;35(4):e21468. PubMed PMID: 33687752
• Niemiec SM, Hilton SA, Wallbank A, Azeltine M, Louiselle AE, Elajaili H, Allawzi A, Xu J, Mattson C, Dewberry LC, Hu J, Singh S, Sakthivel TS, Sea S, Nozik-Grayck E, Smith B, Zgheib C, Liechty KW. Cerium oxide nanoparticle delivery of microRNA-146a for local treatment of acute lung injury. Nanomedicine. 2021 Jun;34:102388. PubMed PMID: 33753282
• Niemiec SM, Hilton SA, Wallbank A, Louiselle AE, Elajaili H, Hu J, Singh S, Seal S, Nozik E, Smith B, Zgheib C, Liechty KW. Lung function improves after delayed treatment with CNP-miR146a following acute lung injury. Nanomedicine. 2021 Nov 26;:102498. [Epub ahead of print] PubMed PMID: 34838994
• Rangarajan S, Locy ML, Chanda D, Kurundkar A, Kurundkar D, Larson-Casey JL, Londono P, Bagchi RA, Deskin B, Elajaili H, Nozik ES, Deshane JS, Zmijewski JW, Eickelberg O, Thannickal VJ. Mitochondrial uncoupling protein-2 reprograms metabolism to induce oxidative stress and myofibroblast senescence in age-associated lung fibrosis. Aging Cell. 2022 Sep;21(9):e13674. PubMed PMID: 35934931
• Madhavan K, Balakrishnan I, Lakshmanachetty S, Pierce A, Sanford B, Fosmire S, Elajaili HB, Walker F, Wang D, Nozik ES, Mitra SS, Dahl NA, Vibhakar R, Venkataraman S. Venetoclax Cooperates with Ionizing Radiation to Attenuate Diffuse Midline Glioma Tumor Growth. Clin Cancer Res. 2022 Jun 1;28(11):2409-2424. PubMed PMID: 35344040
• Colon Hidalgo D, Elajaili H, Suliman H, George MP, Delaney C, Nozik E. Metabolism, Mitochondrial Dysfunction, and Redox Homeostasis in Pulmonary Hypertension. Antioxidants (Basel). 2022 Feb 21;11(2). PubMed PMID: 35204311
• Soranno DE, Baker P 2nd, Kirkbride-Romeo L, Wennersten SA, Ding K, Keith B, Cavasin MA, Altmann C, Bagchi RA, Haefner KR, Montford J, Gist KM, Vergnes L, Reue K, He Z, Elajaili H, Okamura K, Nozik E, McKinsey TA, Faubel S. Female and male mice have differential longterm cardiorenal outcomes following a matched degree of ischemia-reperfusion acute kidney injury. Sci Rep. 2022 Jan 12;12(1):643. PubMed PMID: 35022484
• Niemiec SM, Hilton SA, Wallbank A, Louiselle AE, Elajaili H, Hu J, Singh S, Seal S, Nozik E, Smith B, Zgheib C, Liechty KW. Lung function improves after delayed treatment with CNP-miR146a following acute lung injury. Nanomedicine. 2022 Feb;40:102498. PubMed PMID: 34838994
• Elajaili H, Hernandez-Lagunas L, Harris P, Sparagna GC, Jonscher R, Ohlstrom D, et al. Extracellular superoxide dismutase (EC-SOD) R213G variant reduces mitochondrial ROS and preserves mitochondrial function in bleomycin-induced lung injury: EC-SOD R213G variant and intracellular redox regulation. Advances in Redox Research. 2022;5:100035.
• Elajaili HB, Dee NM, Dikalov SI, Kao JPY, Nozik ES. Use of Electron Paramagnetic Resonance (EPR) to Evaluate Redox Status in a Preclinical Model of Acute Lung Injury. Mol Imaging Biol. 2023 May 16;:1-8. [Epub ahead of print] PubMed PMID: 37193807
• Elajaili HB, Woodcock LB, Hovey TA, Rinard GA, DeGraw S, Canny A, Dee NM, Kao JPY, Nozik ES, Eaton SS, Eaton GR. Imaging Reactive Oxygen Radicals in Excised Mouse Lung Trapped by Reaction with Hydroxylamine Probes Using 1 GHz Rapid Scan Electron Paramagnetic Resonance. Mol Imaging Biol. 2023 Oct 11. [Epub ahead of print] PubMed PMID: 37821714