My research explores personalized risk assessment, lifestyle recommendations, and potential disease-altering approaches for those most likely to benefit. I have a passion for preventing dementia. I have an interest in cognitive decline in Parkinson's disease focusing on modifiable and/or treatable risk factors. I am also interested in sex differences in Alzheimer's disease. I am also interested in the real-world response to anti-amyloid therapies - and other potentially disease-modifying therapies that will be available in the future - in populations not well-represented in the original clinical trials.
Teaching
Assistant Professor
(2022)
School of Medicine,
Neurology
Cognition across the lifespan, cognitive decline, and neurodegenerative disorders.
Publications
Carlisle TC, Medina LD, Holden SK. Original research: initial development of a pragmatic tool to estimate cognitive decline risk focusing on potentially modifiable factors in Parkinson's disease. Front Neurosci. 2023;17:1278817. PubMed PMID: 37942138
Carlisle TC, Fought AJ, Olson KE, Lopez-Esquibel N, Simpson A, Medina LD, Holden SK. Original research: longitudinal evaluation of cognitively demanding daily function using performance-based functional assessment highlights heterogeneous trajectories in cognitive and functional abilities in people with Parkinson's disease. Front Neurosci. 2023;17:1200347. PubMed PMID: 37434765
Carlisle, T.C., Olson, K.E., Carlson, N.E., Bettcher, B., Holden, S.K. Developing a Preliminary Parkinson’s Disease Risk Estimator for Decline In Cognition Tool (pPREDICT) as a Practical and Pragmatic Tool to Estimate Risk of Cognitive Decline. Abstract for Virtual Poster Presentation. American Academy of Neurology Annual Meeting, April 2022.
Carlisle, T.C., Olson, K.E., Carlson, N.E., Bettcher, B., Holden, S.K. Variable Cognitive Trajectories in Parkinson’s Disease. Abstract for Virtual Poster Presentation. 32nd Annual Meeting of the American Neuropsychiatric Association, March 2022.
Macchi ZA, Carlisle TC, Filley CM. Prognosis in substance abuse-related acute toxic leukoencephalopathy: A scoping review. J Neurol Sci. 2022 Nov 15;442:120420. PubMed PMID: 36156344
Carlisle TC, Birlea M, Restrepo D, Filley CM. Headache-Associated Phantosmia as a Harbinger of Lewy Body Dementia. J Neuropsychiatry Clin Neurosci. 2022 Aug 22;:appineuropsych21110265. [Epub ahead of print] PubMed PMID: 35989571
Macchi ZA, Carlisle TC, Filley CM. Prognosis in substance abuse-related acute toxic leukoencephalopathy: A scoping review. J Neurol Sci. 2022 Nov 15;442:120420. PubMed PMID: 36156344
Carlisle TC, Stanley MPH, Singhal AB, Caplan DN. Clinical Reasoning: An 81-Year-Old Woman Who Insisted the Hospital Was Her Home. Neurology. 2021 Oct 19;97(16):e1632-e1636. PubMed PMID: 34144999
Carlisle, T.C., Fought, A., Medina, L.D., Olson, K., Lopez-Esquibel, N., Simpson, A.E., and Holden, S.K. Longitudinal validity of UCSD performance-based skills assessment in Parkinson’s disease. Poster Presentation. American Academy of Neurology Annual Meeting, April 2021.
Holden, S.K., Fought, A., Olson, K., Lopez-Esquibel, N., Carlisle, T.C., and Medina, L.D. Initial longitudinal analyses of objectively assessed cognitive functional abilities in a cohort with Parkinson’s disease. Poster Presentation. Movement Disorders Society Congress, September 2021.
Carlisle TC, Stanley MPH, Singhal AB, Caplan DN. Clinical Reasoning: An 81-Year-Old Woman Who Insisted the Hospital Was Her Home. Neurology. 2021 Oct 19;97(16):e1632-e1636. PubMed PMID: 34144999
Carlisle TC, Galetta KM, McGinnis SM, Bockow Kaplan T. Clinical Reasoning: A 58-year-old woman presents with progressive memory deficits, odd behavior, and falls. Neurology. 2020 Feb 4;94(5):e557-e561. PubMed PMID: 31959711
Carlisle TC, Galetta KM, McGinnis SM, Bockow Kaplan T. Clinical Reasoning: A 58-year-old woman presents with progressive memory deficits, odd behavior, and falls. Neurology. 2020 Feb 4;94(5):e557-e561. PubMed PMID: 31959711
Carlisle TC, Ribera AB. Connexin 35b expression in the spinal cord of Danio rerio embryos and larvae. J Comp Neurol. 2014 Mar;522(4):861-75. PubMed PMID: 23939687
Carlisle TC, Ribera AB. Connexin 35b expression in the spinal cord of Danio rerio embryos and larvae. J Comp Neurol. 2014 Mar;522(4):861-75. PubMed PMID: 23939687
Martin, T.C. and Ribera, A.B. (2013). Lessons from Zebrafish: Ion Channels Guide Neuronal Development. In Cellular Migration and Formation of Neuronal Connections: Comprehensive Developmental Neuroscience (Rakic, P., Rubenstein, J.L.R. eds.) Chapter 42: 791-809. San Diego: Elsevier.
Martin (Carlisle), T.C. and Ribera, A.B. (2013). Lessons from Zebrafish: Ion Channels Guide Neuronal Development. In Cellular Migration and Formation of Neuronal Connections: Comprehensive Developmental Neuroscience (Rakic, P., Rubenstein, J.L.R. eds.) Chapter 42: 791-809. San Diego: Elsevier.
Brain and Nervous System - Dementia with Lewy Bodies
Brain and Nervous System - Frontotemporal Dementia
Brain and Nervous System - Hydrocephalus
Brain and Nervous System - Lewy Body Dementia
Brain and Nervous System - Memory disorders
Brain and Nervous System - Memory Loss
Brain and Nervous System - Mild Cognitive Impairment
Brain and Nervous System - Parkinson's Disease Dementia
Brain and Nervous System - Posterior Cortical Atrophy
Care Philosophy
I strive to provide the best care for my patients. I believe in treating the person as a whole, taking every aspect of brain health into consideration during diagnosis and treatment.
Public Speaking Yes
Neurodegenerative disorders, healthy aging
General Information
Medical Schools:
MD, University of Colorado Denver School of Medicine
(2007)
Graduate Schools:
PhD, University of Colorado Health Sciences Center
(2007)
Undergraduate Schools:
BA/BS, University of Colorado - Boulder (CO)
(2002)
Internships:
University of Colorado (University Hospital) Program
(2016)
Residency Programs:
Brigham and Women's Hospital/Massachusetts General Hospital/Harvard Medical School Program, Neurology (2017)
Fellowships:
University of Colorado (University Hospital) Program, Neurology
(2020)