Niranjan Manoharan, MD

Recognitions

• Fellow’s Teaching Award, UCLA, Jules Stein Eye Institute (2020)
• John and Theiline McCone Fellow, UCLA, Jules Stein Eye Institute (2018)
• Selected to attend 12th Annual Heed Ophthalmic Foundation Residents Retreat, Heed Ophthalmic Foundation (2017)
• Ambassador Travel Grant, AAO Congressional Advocacy Day – Mid-Year Forum (2017)
• Alpha Omega Alpha Honor Society, Medical College of Wisconsin (2013)
• Dr. Michael J. Dunn Poster Contest Award, Medical College of Wisconsin Research Symposium (2012)
• Provost’s Honor, University of California, San Diego (2010)
• Faculty Teaching Award, University of Colorado. Residency Program, Department of Ophthalmology (2024)

Research Interests

My research interests are primary focused on vitreoretinal diseases and surgery including imaging biomarkers for retinal disease, proliferative vitreoretinopathy, retinal vascular diseases, and surgical outcomes of vitreoretinal pathology.

Publications

• Kothari N, Chu A, Huang JM, Lin F, Lin BR, Manoharan N, Gui W, Huang AS, Tsui I. Arm-mounted optical coherence tomography angiography in extremely low birth weight neonates with retinopathy of prematurity. Am J Ophthalmol Case Rep. 2020 Jun;18:100624. PubMed PMID: 32154434
• Manoharan N, Patnaik JL, Olson JL. INCREASED COMPLEMENT LEVELS IN HUMAN VITREOUS ASPIRATES OF PROLIFERATIVE DIABETIC RETINOPATHY AND RETINAL DETACHMENT EYES. Retina. 2019 Nov;39(11):2212-2218. PubMed PMID: 30148749
• Manoharan N, Patnaik JL, Bonnell LN, SooHoo JR, Pantcheva MB, Kahook MY, Wagner BD, Lynch AM, Seibold LK. Refractive outcomes of phacoemulsification cataract surgery in glaucoma patients. J Cataract Refract Surg. 2018 Mar;44(3):348-354. PubMed PMID: 29605284
• Haines NR, Manoharan N, Olson JL, D'Alessandro A, Reisz JA. Metabolomics Analysis of Human Vitreous in Diabetic Retinopathy and Rhegmatogenous Retinal Detachment. J Proteome Res. 2018 Jul 6;17(7):2421-2427. PubMed PMID: 29877085
• Manoharan N, Subramanian PS. A case of non-arteritic anterior ischemic optic neuropathy after completion of Harvoni therapy. Am J Ophthalmol Case Rep. 2017 Jun;6:55-57. PubMed PMID: 29260058
• Malarkannan S, Awasthi A, Rajasekaran K, Kumar P, Schuldt KM, Bartoszek A, Manoharan N, Goldner NK, Umhoefer CM, Thakar MS. IQGAP1: a regulator of intracellular spacetime relativity. J Immunol. 2012 Mar 1;188(5):2057-63. PubMed PMID: 22345702
• Manoharan N, Pecen PE, Cherof AM, Oliver SCN, Palestine AG. Comparison of Oral Versus Intravenous Fluorescein Widefield Angiography in Ambulatory Pediatric Patients. Journal of VitreoRetinal Diseases. 2017;1(3):191-196.
• Chehaibou I, Manoharan N, Govetto A, Francone AA, Sarraf D, Hubschman JP. Comparison of vitreoretinal disorders in fellow eyes of lamellar macular holes versus epiretinal membrane foveoschisis. Graefes Arch Clin Exp Ophthalmol. 2020 Dec;258(12):2611-2619. PubMed PMID: 33009974
• Chehaibou I, Manoharan N, Govetto A, Tsui I, Hubschman JP. SPONTANEOUS LAMELLAR MACULAR HOLES CLOSURE. Retin Cases Brief Rep. 2020 Sep 7. [Epub ahead of print] PubMed PMID: 32910024
• Chehaibou I, Manoharan N, Govetto A, Francone AA, Sarraf D, Hubschman JP. Comparison of vitreoretinal disorders in fellow eyes of lamellar macular holes versus epiretinal membrane foveoschisis. Graefes Arch Clin Exp Ophthalmol. 2020 Dec;258(12):2611-2619. PubMed PMID: 33009974
• Olson JL, Velez-Montoya R, Mackin A, Manoharan N, Mueller N, Erlanger M. Vitreous protein binding with nanopore dialysis membrane device. Biomed Microdevices. 2020 Jul 4;22(3):46. PubMed PMID: 32623529
• Chehaibou I, Manoharan N, Govetto A, Tsui I, Hubschman JP. SPONTANEOUS LAMELLAR MACULAR HOLES CLOSURE. Retin Cases Brief Rep. 2020 Sep 7. [Epub ahead of print] PubMed PMID: 32910024
• Olson JL, Velez-Montoya R, Mackin A, Manoharan N, Mueller N, Erlanger M. Vitreous protein binding with nanopore dialysis membrane device. Biomed Microdevices. 2020 Jul 4;22(3):46. PubMed PMID: 32623529
• Kothari N, Chu A, Huang JM, Lin F, Lin BR, Manoharan N, Gui W, Huang AS, Tsui I. Arm-mounted optical coherence tomography angiography in extremely low birth weight neonates with retinopathy of prematurity. Am J Ophthalmol Case Rep. 2020 Jun;18:100624. PubMed PMID: 32154434
• Kothari N, Chu A, Huang JM, Lin F, Lin BR, Manoharan N, Gui W, Huang AS, Tsui I. Arm-mounted optical coherence tomography angiography in extremely low birth weight neonates with retinopathy of prematurity. Am J Ophthalmol Case Rep. 2020 Jun;18:100624. PubMed PMID: 32154434
• Manoharan N, Patnaik JL, Olson JL. INCREASED COMPLEMENT LEVELS IN HUMAN VITREOUS ASPIRATES OF PROLIFERATIVE DIABETIC RETINOPATHY AND RETINAL DETACHMENT EYES. Retina. 2019 Nov;39(11):2212-2218. PubMed PMID: 30148749
• Manoharan, N., 2019. Secondary Intraocular Lens. In: Intraocular Lens. IntechOpen.
• Kothari, N., Manoharan, N. and Tsui, I., 2020. Pediatric Flourescein Angiography. In: M. Hartnett, ed., Pediatric Retina, 3rd ed. LWW.
• Milner DC, Le C, Marin AI, Smith JM, Manoharan N. Outcomes of chronic macula-off retinal detachment repair. Graefes Arch Clin Exp Ophthalmol. 2022 Oct 27;:1-6. [Epub ahead of print] PubMed PMID: 36289075
• Brittany M. Wong, Alison Chu, Nicholas N Zoppi, Niranjan Manoharan, Artemiy Kokhanov, Alex S. Huang, Irena Tsui; Cystoid macular edema on optical coherence tomography correlated with worse intraventricular hemorrhage in preterm neonates. Invest. Ophthalmol. Vis. Sci. 2020;61(7):2170.
• Rabina G, Chehaibou I, Manoharan N, Ip M. New Drug Application for Brilliant Blue G Accepted. Ocular Surgery News. July 2019.
• Fonteh CN, Mathias MT, Mandava N, Manoharan N, Lynch AM, Navo R, Patnaik JL. Mental health and visual acuity in patients with age-related macular degeneration. BMC Ophthalmol. 2022 Oct 2;22(1):391. PubMed PMID: 36183081
• Sidhu S, Lynch AM, Mandava N, Manoharan N, Mathias MT, Patnaik JL. Gender Differences in Visual Functioning Questionnaire Scores among Patients with Age-Related Macular Degeneration. Ophthalmic Epidemiol. 2022 Jul 17;:1-10. [Epub ahead of print] PubMed PMID: 35848204
• Marin AI, Poppelaars F, Wagner BD, Palestine AG, Patnaik JL, Holers VM, Frazer-Abel AA, Mathias MT, Manoharan N, Fonteh CN, Mandava N, Lynch AM. Sex and Age-Related Differences in Complement Factors Among Patients With Intermediate Age-Related Macular Degeneration. Transl Vis Sci Technol. 2022 May 2;11(5):22. PubMed PMID: 35594041
• Ramtohul P, Iovino C, Au A, Bacci T, Pichi F, Corradetti G, Corvi F, Manoharan N, Marin AI, Tadayoni R, Sadda S, Freund KB, Sarraf D. Clinical and Morphologic Characteristics of Perivenular Fernlike Leakage on Ultrawide-field Fluorescein Angiography. Ophthalmol Retina. 2022 Nov;6(11):1070-1079. PubMed PMID: 35545196
• Chehaibou I, Manoharan N, Govetto A, Tsui I, Hubschman JP. SPONTANEOUS LAMELLAR MACULAR HOLES CLOSURE. Retin Cases Brief Rep. 2022 Jul 1;16(4):397-400. PubMed PMID: 32910024
• Scott RA, Lu VI, Grove N, Patnaik JL, Manoharan N. Rates of diabetic retinopathy among cluster analysis-identified type 2 diabetic mellitus subgroups. Graefes Arch Clin Exp Ophthalmol. 2023 Oct 16. [Epub ahead of print] PubMed PMID: 37843564
• Gill ZS, Marin AI, Caldwell AS, Mehta N, Grove N, Seibold LK, Puente MA, De Carlo Forest TE, Oliver SCN, Patnaik JL, Manoharan N. Limited English Proficiency Is Associated With Diabetic Retinopathy in Patients Presenting for Cataract Surgery. Transl Vis Sci Technol. 2023 Oct 3;12(10):4. PubMed PMID: 37796496
• Chehaibou, I, Manoharan N, Hubschman, JP. Findings From the Fellow Eyes of Lamellar Macula Hole: A Bilateral Degenerative Condition? ARVO Annual Meeting. 2019 April; Vancouver, Canada.
• Lu VI, Patnaik JL, Scott RA, Lynch AM, Smith JM, Mandava N, Manoharan N. Risk Factors and Outcomes of Delayed Presentation of Diabetic Retinopathy Patients to a County Hospital. Transl Vis Sci Technol. 2023 Sep 1;12(9):8. PubMed PMID: 37676677
• Rajeswaren V, Wagner BD, Patnaik JL, Mandava N, Mathias MT, Manoharan N, De Carlo Forest TE, Gnanaraj R, Lynch AM, Palestine AG. Interleukin-4 Plasma Levels Stratified by Sex in Intermediate Age-Related Macular Degeneration and Geographic Atrophy. Transl Vis Sci Technol. 2023 Aug 1;12(8):1. PubMed PMID: 37526620
• Lynch AM, McReynolds AJ, Wittel RJ, Mathias MT, Manoharan N, Emerick LM, Brocious ML, Patnaik JL. The use of social and digital media to recruit patients with early and intermediate age-related macular degeneration. Clin Exp Ophthalmol. 2023 May-Jun;51(4):398-401. PubMed PMID: 37062710
• Fonteh CN, Palestine AG, Wagner BD, Patnaik JL, Mathias MT, Manoharan N, Mandava N, Baldermann R, De Carlo T, Lynch AM. RANTES (CCL5) in Patients With Geographic Atrophy Age-Related Macular Degeneration. Transl Vis Sci Technol. 2023 Jan 3;12(1):19. PubMed PMID: 36633873
• Milner DC, Le C, Marin AI, Smith JM, Manoharan N. Outcomes of chronic macula-off retinal detachment repair. Graefes Arch Clin Exp Ophthalmol. 2023 Mar;261(3):709-714. PubMed PMID: 36289075
• Fonteh CN, Mathias MT, Mandava N, Manoharan N, Lynch AM, Navo R, Patnaik JL. Mental health and visual acuity in patients with age-related macular degeneration. BMC Ophthalmol. 2022 Oct 2;22(1):391. PubMed PMID: 36183081
• Chehaibou I, Manoharan N, Govetto A, Tsui I, Hubschman JP. SPONTANEOUS LAMELLAR MACULAR HOLES CLOSURE. Retin Cases Brief Rep. 2022 Jul 1;16(4):397-400. PubMed PMID: 32910024
• Ramtohul P, Iovino C, Au A, Bacci T, Pichi F, Corradetti G, Corvi F, Manoharan N, Marin AI, Tadayoni R, Sadda S, Freund KB, Sarraf D. Clinical and Morphologic Characteristics of Perivenular Fernlike Leakage on Ultrawide-field Fluorescein Angiography. Ophthalmol Retina. 2022 Nov;6(11):1070-1079. PubMed PMID: 35545196
• Marin AI, Poppelaars F, Wagner BD, Palestine AG, Patnaik JL, Holers VM, Frazer-Abel AA, Mathias MT, Manoharan N, Fonteh CN, Mandava N, Lynch AM. Sex and Age-Related Differences in Complement Factors Among Patients With Intermediate Age-Related Macular Degeneration. Transl Vis Sci Technol. 2022 May 2;11(5):22. PubMed PMID: 35594041
• Sidhu S, Lynch AM, Mandava N, Manoharan N, Mathias MT, Patnaik JL. Gender Differences in Visual Functioning Questionnaire Scores among Patients with Age-Related Macular Degeneration. Ophthalmic Epidemiol. 2022 Jul 17;:1-10. [Epub ahead of print] PubMed PMID: 35848204
• Khanani AM, Patel SS, Staurenghi G, Tadayoni R, Danzig CJ, Eichenbaum DA, Hsu J, Wykoff CC, Heier JS, Lally DR, Monés J, Nielsen JS, Sheth VS, Kaiser PK, Clark J, Zhu L, Patel H, Tang J, Desai D, Jaffe GJ. Efficacy and safety of avacincaptad pegol in patients with geographic atrophy (GATHER2): 12-month results from a randomised, double-masked, phase 3 trial. Lancet. 2023 Oct 21;402(10411):1449-1458. PubMed PMID: 37696275

Professional Memberships

• American Medical Association, Member
• Alpha Omega Alpha, Member
• Colorado Society of Eye Physicians and Surgeons, Member
• American Academy of Ophthalmology, Member
• American Society of Retina Specialists, Member

Practice Locations

UCHealth Sue Anschutz-Rodgers Eye Center
1675 Aurora Ct
Aurora, CO 80045
720-848-2020

UCHealth Eye Center - Cherry Creek
2000 S. Colorado Blvd
Annex Bldg., Suite 100
Denver, CO 80222
720-553-2020

Hospital Affiliation

• University of Colorado Hospital
• Denver Health Medical Center
• Veterans Affairs Medical Center
• Children's Hospital Colorado

Specialty Information

Specialties

• Ophthalmology, Board Certification
• Vitreoretinal Diseases and Surgery, Specialized Training (0001)

Conditions & Treatments

• Eyes and Vision
• Eyes and Vision - Diabetic Eye Disease
• Eyes and Vision - Eye Disease
• Eyes and Vision - Macular Degeneration
• Eyes and Vision - Retinal Detachment
• Failed Prior Surgery
• Surgery - Eye and/or Orbital Surgery
• Surgery
• Endocrine System (Hormones) - Diabetic Retinopathy
• Endocrine System (Hormones)