Andrew Goodspeed, PhD

Publications

• Jones RT, Scholtes M, Goodspeed A, Akbarzadeh M, Mohapatra S, Feldman LE, Vekony H, Jean A, Tilton CB, Orman MV, Romal S, Deiter C, Kan TW, Xander N, Araki SP, Joshi M, Javaid M, Clambey ET, Layer R, Laajala TD, Parker SJ, Mahmoudi T, Zuiverloon TCM, Theodorescu D, Costello JC. NPEPPS Is a Druggable Driver of Platinum Resistance. Cancer Res. 2024 May 15;84(10):1699-1718. doi: 10.1158/0008-5472.CAN-23-1976. PMID: 38535994; PMCID: PMC11094426.
• Elias AD, Staley AW, Fornier M, Vidal GA, Alami V, Sams S, Spoelstra NS, Goodspeed A, Kabos P, Diamond JR, Shagisultanova E, Gallagher RI, Wulfkuhle JD, Petricoin EF, Zolman KL, McSpadden T, Jordan KR, Slansky JE, Borges VF, Gao D, Richer JK. Clinical and immune responses to neoadjuvant fulvestrant with or without enzalutamide in ER+/Her2- breast cancer. NPJ Breast Cancer. 2024 Oct 6;10(1):88. doi: 10.1038/s41523-024-00697-5. PMID: 39368973; PMCID: PMC11455938.
• Steller JG, Blue RS, Ronca AE, Goodspeed A, Powell TL, Jansson T. Impact of near continuous low dose rate neutron irradiation on pregnancy outcomes in mice. NPJ Microgravity. 2024 Dec 19;10(1):113. doi: 10.1038/s41526-024-00438-9. PMID: 39702580; PMCID: PMC11659551.
• Pham-Danis C, Chia SB, Scarborough HA, Danis E, Nemkov T, Zaberezhnyy V … Goodspeed A, et al. Inflammation Promotes Aging-Associated Oncogenesis in the Lung. Aging and Cancer 2024; e12077; doi:10.1002/aac2.12077.
• Mills TS, Kain B, Burchill MA, Danis E, Lucas ED, Culp-Hill R, Cowan CM, Schleicher WE, Patel SB, Tran BT, Cao R, Goodspeed A, Ferrara S, Bevers S, Jirón Tamburini BA, Roede JR, D'Alessandro A, King KY, Pietras EM. A distinct metabolic and epigenetic state drives trained immunity in HSC-derived macrophages from autoimmune mice. Cell Stem Cell. 2024 Nov 7;31(11):1630-1649.e8. doi: 10.1016/j.stem.2024.09.010. Epub 2024 Oct 15. PMID: 39413777; PMCID: PMC11560650.
• Kuo LW, Crump LS, O'Neill K, Williams MM, Christenson JL, Spoelstra NS, Roy MK, Argabright A, Reisz JA, D'Alessandro A, Boorgula MP, Goodspeed A, Bickerdike M, Bitler BG, Richer JK. Blocking Tryptophan Catabolism Reduces Triple-Negative Breast Cancer Invasive Capacity. Cancer Res Commun. 2024 Oct 1;4(10):2699-2713. doi: 10.1158/2767-9764.CRC-24-0272. PMID: 39311710; PMCID: PMC11484926.
• Shirai R, Biebighauser T, Walker D, Oviedo J, Nelson-Taylor S, Bodlak A, Porfilio T, Oike N, Goodspeed A, Hayashi M. Cadherin-11 contributes to the heterogenous and dynamic Wnt-Wnt-ß-catenin pathway activation in Ewing sarcoma. PLoS One. 2024 Jun 14;19(6):e0305490. doi: 10.1371/journal.pone.0305490. PMID: 38875295; PMCID: PMC11178195.
• Hawkins HJ, Yacob BW, Brown ME, Goldstein BR, Arcaroli JJ, Bagby SM, Hartman SJ, Macbeth M, Goodspeed A, Danhorn T, Lentz RW, Lieu CH, Leal AD, Messersmith WA, Dempsey PJ, Pitts TM. Examination of Wnt signaling as a therapeutic target for pancreatic ductal adenocarcinoma (PDAC) using a pancreatic tumor organoid library (PTOL). PLoS One. 2024 Apr 10;19(4):e0298808. doi: 10.1371/journal.pone.0298808. PMID: 38598488; PMCID: PMC11006186.
• Thomas SN, Niemeyer BF, Jimenez-Valdes RJ, Kaiser AJ, Espinosa JM, Sullivan KD, Goodspeed A, Costello JC, Alder JK, Cañas-Arranz R, García-Sastre A, Benam KH. Down syndrome is associated with altered frequency and functioning of tracheal multiciliated cells, and response to influenza virus infection. iScience. 2023 Aug 18;26(8):107361. PubMed PMID: 37554445