Alexa Burger, PhD

Visiting Associate Professor, Orthopedics


FacultyPhoto
Department
Orthopedics

Publications

  • D'Agati G, Cabello EM, Frontzek K, Rushing EJ, Klemm R, Robinson MD, White RM, Mosimann C, Burger A. Active receptor tyrosine kinases, but not Brachyury, are sufficient to trigger chordoma in zebrafish. Dis Model Mech. 2019 Jul 16;12(7). PubMed PMID: 31221659
  • Brunner E, Yagi R, Debrunner M, Beck-Schneider D, Burger A, Escher E, Mosimann C, Hausmann G, Basler K. CRISPR-induced double-strand breaks trigger recombination between homologous chromosome arms. Life Sci Alliance. 2019 Jun;2(3). PubMed PMID: 31196871
  • Prummel KD, Hess C, Nieuwenhuize S, Parker HJ, Rogers KW, Kozmikova I, Racioppi C, Brombacher EC, Czarkwiani A, Knapp D, Burger S, Chiavacci E, Shah G, Burger A, Huisken J, Yun MH, Christiaen L, Kozmik Z, Müller P, Bronner M, Krumlauf R, Mosimann C. A conserved regulatory program initiates lateral plate mesoderm emergence across chordates. Nat Commun. 2019 Aug 26;10(1):3857. PubMed PMID: 31451684
  • Lalonde RL, Kemmler CL, Riemslagh FW, Aman AJ, Kresoja-Rakic J, Moran HR, Nieuwenhuize S, Parichy DM, Burger A, Mosimann C. Heterogeneity and genomic loci of ubiquitous transgenic Cre reporter lines in zebrafish. Dev Dyn. 2022 Oct;251(10):1754-1773. PubMed PMID: 35582941
  • Mattonet K, Riemslagh FW, Guenther S, Prummel KD, Kesavan G, Hans S, Ebersberger I, Brand M, Burger A, Reischauer S, Mosimann C, Stainier DYR. Endothelial versus pronephron fate decision is modulated by the transcription factors Cloche/Npas4l, Tal1, and Lmo2. Sci Adv. 2022 Sep 2;8(35):eabn2082. PubMed PMID: 36044573
  • Melica ME, Antonelli G, Semeraro R, Angelotti ML, Lugli G, Landini S, Ravaglia F, Regina G, Conte C, De Chiara L, Peired AJ, Mazzinghi B, Donati M, Molli A, Steiger S, Magi A, Bartalucci N, Raglianti V, Guzzi F, Maggi L, Annunziato F, Burger A, Lazzeri E, Anders HJ, Lasagni L, Romagnani P. Differentiation of crescent-forming kidney progenitor cells into podocytes attenuates severe glomerulonephritis in mice. Sci Transl Med. 2022 Aug 10;14(657):eabg3277. PubMed PMID: 35947676
  • Prummel KD, Crowell HL, Nieuwenhuize S, Brombacher EC, Daetwyler S, Soneson C, Kresoja-Rakic J, Kocere A, Ronner M, Ernst A, Labbaf Z, Clouthier DE, Firulli AB, Sánchez-Iranzo H, Naganathan SR, O'Rourke R, Raz E, Mercader N, Burger A, Felley-Bosco E, Huisken J, Robinson MD, Mosimann C. Hand2 delineates mesothelium progenitors and is reactivated in mesothelioma. Nat Commun. 2022 Mar 30;13(1):1677. PubMed PMID: 35354817
  • Kemmler CL, Smolikova J, Moran HR, Mannion BJ, Knapp D, Lim F, Czarkwiani A, Hermosilla Aguayo V, Rapp V, Fitch OE, Bötschi S, Selleri L, Farley E, Braasch I, Yun M, Visel A, Osterwalder M, Mosimann C, Kozmik Z, Burger A. Conserved enhancers control notochord expression of vertebrate Brachyury. Nat Commun. 2023 Oct 18;14(1):6594. PubMed PMID: 37852970
  • Kocere A, Lalonde RL, Mosimann C, Burger A. Lateral thinking in syndromic congenital cardiovascular disease. Dis Model Mech. 2023 May 1;16(5). PubMed PMID: 37125615
  • Kocere A, Chiavacci E, Méndez-Acevedo KM, Soneson C, Hiltabidle MS, Raghunath A, MacGowan JS, Shavit JA, Panáková D, Williams MLK, Robinson MD, Mosimann C, Burger A. TAR Syndrome-associated Rbm8a deficiency causes hematopoietic defects and attenuates Wnt/PCP signaling. bioRxiv. 2023 Apr 20. PubMed PMID: 37090609
  • Kemmler CL, Moran HR, Murray BF, Scoresby A, Klem JR, Eckert RL, Lepovsky E, Bertho S, Nieuwenhuize S, Burger S, D'Agati G, Betz C, Puller AC, Felker A, Ditrychova K, Bötschi S, Affolter M, Rohner N, Lovely CB, Kwan KM, Burger A, Mosimann C. Next-generation plasmids for transgenesis in zebrafish and beyond. Development. 2023 Apr 15;150(8). PubMed PMID: 36975217
  • Lalonde RL, Wells HH, Kemmler CL, Nieuwenhuize S, Lerma R, Alxa Burger A, Mosimann C pIGLET: Safe harbor landing sites for reproducible and efficient transgenesis in zebrafish. bioRxiv. 2023 Dec 13. doi: https://doi.org/10.1101/2023.12.08.570868
  • Moran HR, Nyarko OO, O'Rourke R, Ching RK, Riemslagh FW, Peña B, Burger A, Sucharov CC, Mosimann C. The pericardium forms as a distinct structure during heart formation. bioRxiv. 2024 Sep 28. PubMed PMID: 39345600
  • Lalonde RL, Wells HH, Kemmler CL, Nieuwenhuize S, Lerma R, Burger A, Mosimann C. pIGLET: Safe harbor landing sites for reproducible and efficient transgenesis in zebrafish. Sci Adv. 2024 Jun 7;10(23):eadn6603. PubMed PMID: 38838146