Matthew Stone, MD

Professional Titles

• Associate Professor
• Surgical Director, Pediatric Heart Transplantation Program

Recognitions

• StARR Program Mentored Research Award, University of Colorado School of Medicine (2024)
• NIH Loan Repayment Program Award Recipient, National Institute of Health/National Heart, Lung, and Blood Institute (2023)
• Ponzio Research Award, Children's Hospital Colorado (2023)
• StARR Program Mentored Research Award, University of Colorado School of Medicine (2023)
• StARR Program Mentored Research Award, University of Colorado School of Medicine (2022)
• Thoracic Surgery Foundation/Society of Thoracic Surgeons Research Award, Society of Thoracic Surgeons (2020)
• All-University Teaching Award Honorable Mention, University of Virginia (2017)
• Hugh Shephard Warren Award for Best Clinical Teacher, University of Virginia (2016)
• John Horsley Memorial Prize for Excellence in Medical Research, University of Virginia (2016)
• Mulholland Teaching Award for Excellence and Dedication in Educating Medical Students, University of Virginia School of Medicine (2016)
• Academic Achievement Award, University of Virginia (2014)
• C. Walton Lillehei Resident Research Award Finalist, American Association of Thoracic Surgeons (2013)
• C. Walton Lillehei Resident Research Award Finalist, American Association of Thoracic Surgeons (2012)
• All-University Young Scientist Award, University of Virginia (2011)
• Arnold P. Gold Foundation Humanism and Excellence in Teaching Award, University of Virginia School of Medicine (2011)
• Arnold P. Gold Foundation Humanism and Excellence in Teaching Award, University of Virginia School of Medicine (2010)

Research Interests

Publications

• Fraser CD 3rd, Morchi R, Stone ML, Jaggers J, Campbell D, Mitchell MB. Donor great vessel free arterial grafts for complex reconstruction during pediatric heart transplantation. JTCVS Tech. 2024 Dec;28:132-138. PubMed PMID: 39669351
• Schäfer M, Di Maria MV, Stone ML, Barker AJ, Carmody KK, Reece TB, Ivy DD, Jaggers J, Mitchell MB. Principal component analysis identified neo-aortic diameter variations post Norwood surgery associated with the single ventricle performance and flow quality. Int J Cardiovasc Imaging. 2024 Dec;40(12):2603-2616. PubMed PMID: 39509019
• Downs EA, Schäfer M, Everitt MD, Aubrey M, Mitchell M, Jaggers J, Campbell D, Stone ML. Inclusive ABO-Incompatible Listing for Pediatric Heart Transplantation Results in Comparable Post-Transplant Rejection-Free Survival in a Single-Center Series. Pediatr Cardiol. 2024 Aug 8. [Epub ahead of print] PubMed PMID: 39115706
• Schäfer M, Miyamoto SD, Jaggers J, Everitt MD, von Alvensleben JC, Campbell DN, Mitchell MB, Stone ML. Non-invasive myocardial tissue deformation and discoordination indices predict cardiac allograft vasculopathy in pediatric heart transplantation patients. Int J Cardiovasc Imaging. 2024 Jul;40(7):1565-1574. PubMed PMID: 38780709
• Iguidbashian J, Malone LJ, Browne LP, Nguyen M, Frank B, Schafer M, Campbell DN, Mitchell MB, Jaggers J, Stone ML. Regional Arch Measurements Differ Between Imaging Modalities in Infants With Aortic Coarctation. Ann Thorac Surg. 2024 Jul;118(1):209-215. PubMed PMID: 38072352
• Iguidbashian J, Feng Z, Colborn KL, Barrett CS, Newman SR, Harris M, Campbell DN, Mitchell MB, Jaggers J, Stone ML. Open Chest Duration Following Congenital Cardiac Surgery Increases Risk for Surgical Site Infection. Pediatr Cardiol. 2024 Aug;45(6):1284-1288. PubMed PMID: 36583758
• Malone LJ, Browne LP, Morgan GJ, Lovell MA, Campbell DN, Jaggers JJ, Leahy RA, Mitchell MB, Mong DA, Weinman JP, Zablah JE, Stone ML. Computed Tomographic Angiography Provides Reliable Coronary Artery Evaluation in Infants With Pulmonary Atresia Intact Ventricular Septum. Semin Thorac Cardiovasc Surg. 2024 Autumn;36(3):336-344. PubMed PMID: 36244628
• Venardos N, Mangham C, Morgan GJ, Zablah JE, Jaggers J, Stone ML. Two-Stage Biventricular Repair of Complex Aortic Atresia. Ann Thorac Surg. 2023 Apr;115(4):e101-e103. PubMed PMID: 35378089
• Stone ML, Schäfer M, von Alvensleben JC, Frank BS, Campbell DN, Mitchell MB, Jaggers J. Left Ventricular Dysfunction Following the Ross-Konno Reconstruction is Independent of the Operation. Pediatr Cardiol. 2023 Feb;44(2):463-471. PubMed PMID: 36370189
• Schäfer M, Mitchell MB, Frank BS, Barker AJ, Stone ML, Jaggers J, von Alvensleben JC, Hunter KS, Friesen RM, Ivy DD, Jacobsen R, Di Maria MV. Myocardial strain-curve deformation patterns after Fontan operation. Sci Rep. 2023 Jul 24;13(1):11912. PubMed PMID: 37488167
• Schäfer M, Di Maria MV, Jaggers J, Stone ML, Campbell DN, Ivy DD, Mitchell MB. Hemi-Fontan and bidirectional Glenn operations result in flow-mediated viscous energy loss at the time of stage II palliation. JTCVS Open. 2023 Dec;16:836-843. PubMed PMID: 38204687
• Stone ML, Schäfer M, von Alvensleben JC, Frank BS, Campbell DN, Mitchell MB, Jaggers J. Left Ventricular Dysfunction Following the Ross-Konno Reconstruction is Independent of the Operation. Pediatr Cardiol. 2023 Feb;44(2):463-471. PubMed PMID: 36370189
• Schäfer M, Di Maria MV, Jaggers J, Stone ML, Campbell DN, Ivy DD, Mitchell MB. Hemi-Fontan and bidirectional Glenn operations result in flow-mediated viscous energy loss at the time of stage II palliation. JTCVS Open. 2023 Dec;16:836-843. PubMed PMID: 38204687
• Iguidbashian J, Malone LJ, Browne LP, Nguyen M, Frank B, Schafer M, Campbell DN, Mitchell MB, Jaggers J, Stone ML. Regional Arch Measurements Differ Between Imaging Modalities in Infants With Aortic Coarctation. Ann Thorac Surg. 2023 Dec 10. [Epub ahead of print] PubMed PMID: 38072352
• Schäfer M, Mitchell MB, Frank BS, Barker AJ, Stone ML, Jaggers J, von Alvensleben JC, Hunter KS, Friesen RM, Ivy DD, Jacobsen R, Di Maria MV. Myocardial strain-curve deformation patterns after Fontan operation. Sci Rep. 2023 Jul 24;13(1):11912. PubMed PMID: 37488167
• Stone ML, Schäfer M, von Alvensleben JC, Frank BS, Campbell DN, Mitchell MB, Jaggers J. Left Ventricular Dysfunction Following the Ross-Konno Reconstruction is Independent of the Operation. Pediatr Cardiol. 2023 Feb;44(2):463-471. PubMed PMID: 36370189
• Venardos N, Mangham C, Morgan GJ, Zablah JE, Jaggers J, Stone ML. Two-Stage Biventricular Repair of Complex Aortic Atresia. Ann Thorac Surg. 2023 Apr;115(4):e101-e103. PubMed PMID: 35378089
• Ali EA, Syed A, Khailova L, Iguidbashian JP, Surez-Pierre A, Klawitter J, Stone ML, Mancuso CA, Frank BS, Davidson JA. Novel biomarkers of necrotizing enterocolitis in neonates undergoing congenital heart disease surgery: a pilot cohort study. J Am Heart Assoc 2023. PMID: 37489765.
• Palmer WH, Leaton LA, Codo AC, Crute B, Roest J, Zhu S, Tobin RP, Hume PS, Stone ML, van Bokhoven A, Gerich ME, McCarter MD, Zhu Y, Janssen WJ, Vivian JP, Trowsdale J, Getahun A, Rossjohn J, Cambier J, Loh L, Norman PJ. Polymorphic KIR3DL3 expression modulates tissue-resident and innate-like T cells. Sci Immunol 2023; 8(84):eade5343. PMID: 37390222.
• Malone LJ, Browne LP, Morgan GJ, Lovell MA, Campbell DN, Jaggers JJ, Leahy RA, Mitchell MB, Mong DA, Weinman JP, Zablah JE, Stone ML. Computed Tomographic Angiography Provides Reliable Coronary Artery Evaluation in Infants With Pulmonary Atresia Intact Ventricular Septum. Semin Thorac Cardiovasc Surg. 2022 Oct 14. [Epub ahead of print] PubMed PMID: 36244628
• Iguidbashian J, Yoeli D, Everitt MD, Campbell DN, Mitchell MB, Jaggers J, Stone ML. Pediatric Heart Transplant Waiting List Times in the US During the COVID-19 Pandemic. JAMA Netw Open. 2022 Oct 3;5(10):e2234874. PubMed PMID: 36206002
• Javadi E, Laudenschlager S, Kheyfets V, Di Maria M, Stone M, Jamali S, Powell AJ, Moghari MH. Predicting Hemodynamic Performance of Fontan Operation for Glenn Physiology using Computational Fluid Dynamics: Ten Patient-specific Cases. J Clin Images Med Case Rep. 2022 Jun;3(6). PubMed PMID: 36339935
• Venardos N, Mangham C, Morgan GJ, Zablah JE, Jaggers J, Stone ML. Two-Stage Biventricular Repair of Complex Aortic Atresia. Ann Thorac Surg. 2022 Apr 2. [Epub ahead of print] PubMed PMID: 35378089
• Freddo AM, Jacobsen RM, Yeung E, Stone ML, Kay JD, Khanna AD. Surgical management and outcomes of endocarditis in adolescents and adults with congenital heart disease. Int J Cardiol 2022.
• Stone ML, Albertz ML, Galambos C, Twite MD, Campbell DN, Di Maria M, Fonseca B, Miyamoto SD, Ing RJ. Multi-Disciplinary Management and Surgical Resection of Intracardiac Fibromas Causing Bilateral Ventricular Outflow Tract Obstructions in an Infant. Semin Cardiothorac Vasc Anesth. 2022 Dec;26(4):315-322. PubMed PMID: 36006828
• Schäfer M, Di Maria MV, Stone ML, Jaggers J, Mitchell MB. Reply from authors: The unbearable weight of shape and flow quality. JTCVS Open. 2022 Jun;10:352-353. PubMed PMID: 36004238
• Schäfer M, Stone ML, Jaggers J, Browne LP, Mitchell MB. Commentary: In vortices veritas-quantitative approach. J Thorac Cardiovasc Surg. 2022 Mar;163(3):964-966. PubMed PMID: 32768303
• Stone ML, Schäfer M, DiMaria MV, von Alvensleben JC, Campbell DN, Jaggers J, Mitchell MB. Diastolic inflow is associated with inefficient ventricular flow dynamics in Fontan patients. J Thorac Cardiovasc Surg. 2022 Mar;163(3):1195-1207. PubMed PMID: 34429192
• Iguidbashian J, Feng Z, Colborn KL, Barrett CS, Newman SR, Harris M, Campbell DN, Mitchell MB, Jaggers J, Stone ML. Open Chest Duration Following Congenital Cardiac Surgery Increases Risk for Surgical Site Infection. Pediatr Cardiol. 2022 Dec 30. [Epub ahead of print] PubMed PMID: 36583758
• Stone ML, Schäfer M, DiMaria MV, von Alvensleben JC, Campbell DN, Jaggers J, Mitchell MB. Diastolic inflow is associated with inefficient ventricular flow dynamics in Fontan patients. J Thorac Cardiovasc Surg. 2021 Jul 17. [Epub ahead of print] PubMed PMID: 34429192
• Darr OA, Stone ML, Mitchell MB, Meier J, Kelley P, Prager JD. Slide Tracheoplasty for Tracheal Cartilaginous Sleeve in a Patient With Apert Syndrome. Ann Thorac Surg. 2021 Dec;112(6):e419-e421. PubMed PMID: 33676902
• Schäfer M, Di Maria MV, Jaggers J, Stone ML, Ivy DD, Barker AJ, Mitchell MB. High-degree Norwood neoaortic tapering is associated with abnormal flow conduction and elevated flow-mediated energy loss. J Thorac Cardiovasc Surg. 2021 Dec;162(6):1791-1804. PubMed PMID: 33653609
• Stone ML, Schäfer M, von Alvensleben JC, Browne LP, Di Maria M, Campbell DN, Jaggers J, Mitchell MB. Increased Aortic Stiffness and Left Ventricular Dysfunction Exist After Truncus Arteriosus Repair. Ann Thorac Surg. 2021 Sep;112(3):809-815. PubMed PMID: 33307069
• Schäfer M, Frank BS, Jacobsen R, Rausch CM, Mitchell MB, Jaggers J, Stone ML, Morgan GJ, Browne LP, Barker AJ, Hunter KS, Ivy DD, Younoszai A, Di Maria MV. Patients with Fontan circulation have abnormal aortic wave propagation patterns: A wave intensity analysis study. Int J Cardiol. 2021 Jan 1;322:158-167. PubMed PMID: 32853667
• Schulick N, Lin Y, Fonseca B, Campbell DN, Stone ML. Surgical Management of Collateral Arch Channel and Aortic Coarctation. J Card Surg 2021.
• SooHoo MM, Stone ML, von Alvensleben JC, Jacobsen R. Management of Atrial Tachyarrhythmias in Adults with Single Ventricle Heart Disease. Curr Treat Options Peds 2021.
• Schäfer M, Frank BS, Jacobsen R, Rausch CM, Mitchell MB, Jaggers J, Stone ML, Morgan GJ, Browne LP, Barker AJ, Hunter KS, Ivy DD, Younoszai A, Di Maria MV. Patients with Fontan circulation have abnormal aortic wave propagation patterns: A wave intensity analysis study. Int J Cardiol. 2021 Jan 1;322:158-167. PubMed PMID: 32853667
• Schäfer M, Stone ML, Jaggers J, Browne LP, Mitchell MB. Commentary: In vortices veritas-quantitative approach. J Thorac Cardiovasc Surg. 2020 Jun 27. [Epub ahead of print] PubMed PMID: 32768303
• Schäfer M, Frank BS, Humphries SM, Hunter KS, Carmody KL, Jacobsen R, Mitchell MB, Jaggers J, Stone ML, Morgan GJ, Barker AJ, Browne LP, Ivy DD, Younoszai A, Di Maria MV. Flow profile characteristics in Fontan circulation are associated with the single ventricle dilation and function: principal component analysis study. Am J Physiol Heart Circ Physiol. 2020 May 1;318(5):H1032-H1040. PubMed PMID: 32167782
• Schäfer M, Barker AJ, Morgan GJ, Jaggers J, Stone ML, Browne LP, Ivy DD, Mitchell MB. Increased systolic vorticity in the left ventricular outflow tract is associated with abnormal aortic flow formations in Tetralogy of Fallot. Int J Cardiovasc Imaging. 2020 Apr;36(4):691-700. PubMed PMID: 31907684
• Schäfer M, Barker AJ, Jaggers J, Morgan GJ, Stone ML, Truong U, Browne LP, Malone L, Ivy DD, Mitchell MB. Abnormal aortic flow conduction is associated with increased viscous energy loss in patients with repaired tetralogy of Fallot. Eur J Cardiothorac Surg. 2020 Mar 1;57(3):588-595. PubMed PMID: 31535124
• Stone M, Choi R, Ing RJ. Optimization of Right Internal Jugular Central Venous Catheter Length in Pediatric Cardiac Surgical Patients. J Cardiothorac Vasc Anesth. 2020 Sep;34(9):2392-2394. PubMed PMID: 32534878
• Jaggers J, Stone M. Commentary: Intraventricular conduit repair for double-outlet right ventricle with noncommitted ventricular septal defect-How bright is the light at the end of the tunnel?. J Thorac Cardiovasc Surg. 2020 Jun;159(6):2404-2405. PubMed PMID: 31669028
• Stone M, Ing RJ, Schwartz L. Risk Stratification for Prolonged Mechanical Ventilation After Cardiac Surgery in Children. J Cardiothorac Vasc Anesth. 2020 Apr;34(4):949-950. PubMed PMID: 31937480
• Venardos N, Stone ML. Surgical considerations and management options in premature and very low birth weight infants with complex congenital heart disease. Current Treatment Options in Pediatrics 2020. [online]
• Schäfer M, Barker AJ, Morgan GJ, Jaggers J, Stone ML, Browne LP, Ivy DD, Mitchell MB. Increased systolic vorticity in the left ventricular outflow tract is associated with abnormal aortic flow formations in Tetralogy of Fallot. Int J Cardiovasc Imaging. 2020 Jan 6. [Epub ahead of print] PubMed PMID: 31907684
• Stone ML, Schäfer M, von Alvensleben JC, Browne LP, Di Maria M, Campbell DN, Jaggers J, Mitchell MB. Increased Aortic Stiffness and Left Ventricular Dysfunction Exist After Truncus Arteriosus Repair. Ann Thorac Surg. 2020 Dec 8. [Epub ahead of print] PubMed PMID: 33307069
• Ing RJ, Stone M. Optimal Positioning of the Inferior Vena Cava Cannula During Cardiac Surgery in Children. J Cardiothorac Vasc Anesth. 2019 May;33(5):1260-1261. PubMed PMID: 30655201
• Stone M, Ing RJ. Transthoracic Ventricular Septal Defect Closure in Children: An Evolving Treatment Strategy as an Alternative to Open Surgical Repair. J Cardiothorac Vasc Anesth. 2019 May;33(5):1267-1268. PubMed PMID: 30217586
• Stone ML, Everitt MD. Primary graft dysfunction: Worry less about organ quality and do more to improve candidate condition. J Heart Lung Transplant. 2019 Jun;38(6):609-610. PubMed PMID: 30885530
• Jaggers J, Stone M. Commentary: Intraventricular conduit repair for double-outlet right ventricle with noncommitted ventricular septal defect-How bright is the light at the end of the tunnel?. J Thorac Cardiovasc Surg. 2019 Sep 17. [Epub ahead of print] PubMed PMID: 31669028
• Schäfer M, Barker AJ, Jaggers J, Morgan GJ, Stone ML, Truong U, Browne LP, Malone L, Ivy DD, Mitchell MB. Abnormal aortic flow conduction is associated with increased viscous energy loss in patients with repaired tetralogy of Fallot. Eur J Cardiothorac Surg. 2019 Sep 18. [Epub ahead of print] PubMed PMID: 31535124

Practice Locations

• Children's Hospital Colorado
• University of Colorado Hospital

Specialty Information

• Surgery, Board Certification (2017)
• Thoracic and Cardiac, Board Certification (2019)
• Congenital Cardiac Surgery, Board Certification (2021)

• Heart and Circulation - Adult Congenital Heart Disease
• Heart and Circulation
• Heart and Circulation - Congenital Heart Disease
• Heart and Circulation - Heart Failure
• Heart and Circulation - Heart Valve Diseases
• Surgery - Cardiothoracic - Congenital Cardiac Surgery
• Surgery
• Surgery - Heart Transplant Surgery