Jasper Heinsbroek, PhD
Assistant Professor, Anesthesiology

Publications

• Giannotti G, Mottarlini F, Heinsbroek JA, Mandel MR, James MH, Peters J. Oxytocin and orexin systems bidirectionally regulate the ability of opioid cues to bias reward seeking. Transl Psychiatry. 2022 Oct 4;12(1):432. PubMed PMID: 36195606
• Gong S, Fayette N, Heinsbroek JA, Ford CP. Cocaine shifts dopamine D2 receptor sensitivity to gate conditioned behaviors. Neuron. 2022 Apr 6;110(7):1272. PubMed PMID: 35390291
• Gong S, Fayette N, Heinsbroek JA, Ford CP. Cocaine shifts dopamine D2 receptor sensitivity to gate conditioned behaviors. Neuron. 2021 Aug 31. [Epub ahead of print] PubMed PMID: 34506723
• Giannotti G, Gong S, Fayette N, Heinsbroek JA, Orfila JE, Herson PS, Ford CP, Peters J. Extinction blunts paraventricular thalamic contributions to heroin relapse. Cell Rep. 2021 Aug 24;36(8):109605. PubMed PMID: 34433067
• Heinsbroek JA, Giannotti G, Mandel MR, Josey M, Aston-Jones G, James MH, Peters J. A common limiter circuit for opioid choice and relapse identified in a rodent addiction model. Nat Commun. 2021 Aug 9;12(1):4788. PubMed PMID: 34373454
• Nall RW, Heinsbroek JA, Nentwig TB, Kalivas PW, Bobadilla AC. Circuit selectivity in drug versus natural reward seeking behaviors. J Neurochem. 2021 Jun;157(5):1450-1472. PubMed PMID: 33420731
• Bobadilla AC, Dereschewitz E, Vaccaro L, Heinsbroek JA, Scofield MD, Kalivas PW. Cocaine and sucrose rewards recruit different seeking ensembles in the nucleus accumbens core. Mol Psychiatry. 2020 Sep 28. [Epub ahead of print] PubMed PMID: 32985600
• Heinsbroek JA, De Vries TJ, Peters J. Glutamatergic Systems and Memory Mechanisms Underlying Opioid Addiction. Cold Spring Harb Perspect Med. 2020 May 27. [Epub ahead of print] PubMed PMID: 32341068
• Heinsbroek JA, Bobadilla AC, Dereschewitz E, Assali A, Chalhoub RM, Cowan CW, Kalivas PW. Opposing Regulation of Cocaine Seeking by Glutamate and GABA Neurons in the Ventral Pallidum. Cell Rep. 2020 Feb 11;30(6):2018-2027.e3. PubMed PMID: 32049028
• Bobadilla AC, Dereschewitz E, Vaccaro L, Heinsbroek JA, Scofield MD, Kalivas PW. Cocaine and sucrose rewards recruit different seeking ensembles in the nucleus accumbens core. Mol Psychiatry. 2020 Dec;25(12):3150-3163. PubMed PMID: 32985600
• Giannotti G, Heinsbroek JA, Yue AJ, Deisseroth K, Peters J. Prefrontal cortex neuronal ensembles encoding fear drive fear expression during long-term memory retrieval. Sci Rep. 2019 Jul 24;9(1):10709. PubMed PMID: 31341176
• Roberts-Wolfe DJ, Heinsbroek JA, Spencer SM, Bobadilla AC, Smith ACW, Gipson CD, Kalivas PW. Transient synaptic potentiation in nucleus accumbens shell during refraining from cocaine seeking. Addict Biol. 2019 May 6;:e12759. [Epub ahead of print] PubMed PMID: 31062493
• Pardo-Garcia TR, Garcia-Keller C, Penaloza T, Richie CT, Pickel J, Hope BT, Harvey BK, Kalivas PW, Heinsbroek JA. Ventral Pallidum Is the Primary Target for Accumbens D1 Projections Driving Cocaine Seeking. J Neurosci. 2019 Mar 13;39(11):2041-2051. PubMed PMID: 30622165