Caroline Hall, MD, PhD

Assistant Professor, Pediatrics-Gastroenterology, Hepatology and Nutrition


FacultyPhoto
Medical School
  • MD, University of Virginia School of Medicine (2012)
Graduate School
  • PhD, University of Virginia - Charlottesville (2012)
Undergraduate School
  • BS, Duke University (NC) (2002)
Internship
  • Washington University/Barnes-Jewish Hospital/St. Louis Children's Hospital (2012)
Residency
  • Washington University/Barnes-Jewish Hospital/St. Louis Children's Hospital, Pediatrics (2015)
Fellowships
  • University of Colorado (Children's Hospital Colorado) Program, Pediatric Gastroenterology (2018)
Department
Pediatrics-Gastroenterology, Hepatology and Nutrition

Professional Titles

  • Assistant Professor

Research Interests

My research interests include investigating the role of mucosal barrier in gastrointestinal disease. I am particularly interested in the role of metabolic components in the diet on homeostasis in the GI tract.

Publications

  • Curtis VF, Cartwright IM, Lee JS, Wang RX, Kao DJ, Lanis JM, Burney KM, Welch N, Hall CHT, Goldberg MS, Campbell EL, Colgan SP. Neutrophils as sources of dinucleotide polyphosphates and metabolism by epithelial ENPP1 to influence barrier function via adenosine signaling. Mol Biol Cell. 2018 Nov 1;29(22):2687-2699. PubMed PMID: 30188771
  • Hall CHT, Lee JS, Murphy EM, Gerich ME, Dran R, Glover LE, Abdulla ZI, Skelton MR, Colgan SP. Creatine Transporter, Reduced in Colon Tissues From Patients With Inflammatory Bowel Diseases, Regulates Energy Balance in Intestinal Epithelial Cells, Epithelial Integrity, and Barrier Function. Gastroenterology. 2020 Sep;159(3):984-998.e1. PubMed PMID: 32433978
  • Constant BD, Dutmer CM, Arnold MA, Hall C, Abbott JK, de Zoeten EF. Cytotoxic T-Lymphocyte-Associated Antigen 4 Haploinsufficiency Mimics Difficult-to-Treat Inflammatory Bowel Disease. Clin Gastroenterol Hepatol. 2021 May 7. [Epub ahead of print] PubMed PMID: 33965572
  • Cartwright IM, Dowdell AS, Lanis JM, Brink KR, Mu A, Kostelecky RE, Schaefer REM, Welch N, Onyiah JC, Hall CHT, Gerich ME, Tabor JJ, Colgan SP. Mucosal acidosis elicits a unique molecular signature in epithelia and intestinal tissue mediated by GPR31-induced CREB phosphorylation. Proc Natl Acad Sci U S A. 2021 May 18;118(20). PubMed PMID: 33972436
  • Wallimann T, Hall CHT, Colgan SP, Glover LE. Creatine Supplementation for Patients with Inflammatory Bowel Diseases: A Scientific Rationale for a Clinical Trial. Nutrients. 2021 Apr 23;13(5). PubMed PMID: 33922654
  • Hall CHT, de Zoeten EF. Understanding very early onset inflammatory bowel disease (VEOIBD) in relation to inborn errors of immunity. Immunol Rev. 2023 Dec 19. [Epub ahead of print] PubMed PMID: 38115672
  • Hall CHT, Lanis JM, Dowdell AS, Murphy EM, Bhagavatula G, Neuhart RM, Vijaya Sai KY, Colgan SP. Fundamental role for the creatine kinase pathway in protection from murine colitis. Mucosal Immunol. 2023 Dec;16(6):817-825. PubMed PMID: 37716510
  • Steiner CA, Koch SD, Evanoff T, Welch N, Kostelecky R, Callahan R, Murphy EM, Nguyen TT, Hall CHT, Lu S, de Zoeten EF, Weiser-Evans MCM, Cartwright IM, Colgan SP. The TNF(?ARE) Mouse as a Model of Intestinal Fibrosis. Am J Pathol. 2023 Aug;193(8):1013-1028. PubMed PMID: 37169343
  • Colgan SP, Wang RX, Hall CHT, Bhagavatula G, Lee JS. Revisiting the "starved gut" hypothesis in inflammatory bowel disease. Immunometabolism (Cobham). 2023 Jan;5(1):e0016. PubMed PMID: 36644501

Professional Memberships

  • NASPGHAN, Member

Practice Locations

Children's Hospital Colorado Anschutz Medical Campus
13123 East 16th Ave
Aurora, CO 80045
720-777-1234

Hospital Affiliation
  • Children's Hospital Colorado

Center Affiliations

Specialty Information

Specialties
  • Pediatrics, Board Certification (2015)
  • Pediatric Gastroenterology
Conditions & Treatments
  • Digestive System
  • Digestive System - Inflammatory Bowel Disease (IBD): Crohn’s disease, ulcerative colitis, microscopic colitis
  • Digestive System - Gastroenterology (Stomach, Bowel, General GI Problems)
  • Digestive System - Colonoscopy
Clinical Interests
My clinical interests include inflammatory bowel disease care as well as care of patients with general gastrointestinal issues.

Care Philosophy
I aim to provide personalized, evidence driven care for patients with gastrointestinal disorders and their parents.