Nalu Navarro-Alvarez, MD

Publications

• Andrews AR, Wang Z, Wilkinson RA, Fishman JA, Sachs DH, Navarro-Alvarez N, Huang CA. Development of transplantable B-cell lymphomas in the MHC-defined miniature swine model. Cancer Cell Int. 2019;19:236. PubMed PMID: 31516393
• Towards the Study of Liver Failure: Protocol for a 90% Extended Hepatectomy in Mice By Maria J. Lizardo Thiebaud, Eduardo Cervantes-Alvarez and Nalu Navarro-Alvarez DOI: 10.5772/intechopen.90245
• Elevated Galectin-3 Plasma Concentrations in Recipients of Allogeneic Hematopoietic Cell Transplantation. Clinical Hematology International. Volume 1, Issue 4, December 2019, Pages 201 - 204 Zachariah DeFilipp1, †, Nalu Navarro-Alvarez2, 3, 4, †, Shuli Li5, Alec R. Andrews2, Ariel Johnson7, Yi-Bin Chen1, Vincent T. Ho6, Jerome Ritz6, Thomas R. Spitzer1, Christene A. Huang2, 7, *
• Pérez-Escobar J, Ramirez-Quesada W, Calle-Rodas DA, Chi-Cervera LA, Navarro-Alvarez N, Aquino-Matus J, Ramírez-Hinojosa JP, Moctezuma-Velázquez C, Torre A. Increased incidence of and microbiologic changes in pyogenic liver abscesses in the Mexican population. World J Hepatol. 2020 Oct 27;12(10):816-828. PubMed PMID: 33200019
• Méndez-Guerrero O, Calle-Rodas DA, Cervantes-Alvarez E, Alatorre-Arenas E, Pérez-Escobar J, Navarro-Alvarez N, Torre A. Renal and brain failure predict mortality of patients with acute-on-chronic liver failure admitted to the intensive care unit. Ann Hepatol. 2020 Oct 19;22:100270. [Epub ahead of print] PubMed PMID: 33091594
• Lizardo-Thiebaud MJ, Cervantes-Alvarez E, Limon-de la Rosa N, Tejeda-Dominguez F, Palacios-Jimenez M, Méndez-Guerrero O, Delaye-Martinez M, Rodriguez-Alvarez F, Romero-Morales B, Liu WH, Huang CA, Kershenobich D, Navarro-Alvarez N. Direct or Collateral Liver Damage in SARS-CoV-2-Infected Patients. Semin Liver Dis. 2020 Aug;40(3):321-330. PubMed PMID: 32886936
• Wen XD, Ren LN, Wang T, Wang XJ, Navarro-Alvarez N, Li LP, Liu WH. Combined lithotripsy of mechanical clamping and electrohydraulics in facilitating endoscopic management of refractory residual biliary calculi after surgery. Sci Rep. 2020 Feb 13;10(1):2604. PubMed PMID: 32054869
• Wen XD, Xiao L, Wang T, Navarro-Alvarez N, Liu WH. Routine guidewire application facilitates cholangioscopy in the management of postoperative residual hepatolithiasis. Dig Endosc. 2018 May;30(3):372-379. PubMed PMID: 29168230
• Navarro-Alvarez N, Vagefi PA. Liver Xenotransplantation in a Nonhuman Primate Model. Methods Mol Biol. 2020;2110:197-211. PubMed PMID: 32002910
• Limon-De La Rosa N, Cervantes-Alvarez E, Navarro-Alvarez N. Increased Hepatic Expression of SARS-CoV-2 Entry Points and Proinflammatory Cytokines in Cirrhosis. Clin Gastroenterol Hepatol. 2022 Jan;20(1):239-241.e3. PubMed PMID: 34481957
• Méndez-Guerrero O, Calle-Rodas DA, Cervantes-Alvarez E, Alatorre-Arenas E, Pérez-Escobar J, Navarro-Alvarez N, Torre A. Renal and brain failure predict mortality of patients with acute-on-chronic liver failure admitted to the intensive care unit. Ann Hepatol. 2021 May-Jun;22:100270. PubMed PMID: 33091594
• Navarro-Alvarez N, Goncalves B, Andrews AR, Wang Z, Wang Z, Harrington E, Shah J, Sachs DH, Eliaz I, Huang CA. The effects of galectin-3 depletion apheresis on induced skin inflammation in a porcine model. J Clin Apher. 2018 Aug;33(4):486-493. PubMed PMID: 29572917
• Navarro-Alvarez N, Machaidze Z, Schuetz C, Zhu A, Liu WH, Shah JA, Vagefi PA, Elias N, Buhler L, Sachs DH, Markmann JF, Yeh H. Xenogeneic Heterotopic Auxiliary Liver transplantation (XHALT) promotes native liver regeneration in a Post-Hepatectomy Liver failure model. PLoS One. 2018;13(11):e0207272. PubMed PMID: 30462716
• Navarro-Alvarez N, Gonçalves BMM, Andrews AR, Sachs DH, Huang CA. A CFA-Induced Model of Inflammatory Skin Disease in Miniature Swine. Int J Inflam. 2018;2018:6916920. PubMed PMID: 30034774
• Li Z, Navarro-Alvarez N, Keeley EJ, Nowell NH, Goncalves BMM, Huang CA, Evans CL. Non-invasive monitoring of skin inflammation using an oxygen-sensing paint-on bandage. Biomed Opt Express. 2017 Oct 1;8(10):4640-4651. PubMed PMID: 29082091
• Eliaz I, Patil A, Navarro-Alvarez N, Wang Z, Eliaz A, Weil E, Wilk B, Sachs DH, Huang CA. Methods for the detection and serum depletion of porcine galectin-3. J Clin Apher. 2017 Oct;32(5):335-341. PubMed PMID: 28083958
• Yoeli D, Mack CL, Navarro-Alvarez N. Role of galectin-3 in the pathogenesis and progression of biliary atresia. Clin Liver Dis (Hoboken). 2022 Nov;20(5):170-174. PubMed PMID: 36447904
• Delgado-Coello B, Navarro-Alvarez N, Mas-Oliva J. The Influence of Interdisciplinary Work towards Advancing Knowledge on Human Liver Physiology. Cells. 2022 Nov 21;11(22). PubMed PMID: 36429123
• Cervantes-Alvarez E, Vilatoba M, Limon-de la Rosa N, Mendez-Guerrero O, Kershenobich D, Torre A, Navarro-Alvarez N. Liver transplantation is beneficial regardless of cirrhosis stage or acute-on-chronic liver failure grade: A single-center experience. World J Gastroenterol. 2022 Oct 28;28(40):5881-5892. PubMed PMID: 36353203
• Cervantes-Alvarez E, Limon-de la Rosa N, Vilatoba M, Pérez-Monter C, Hurtado-Gomez S, Martinez-Cabrera C, Argemi J, Alatorre-Arenas E, Yarza-Regalado S, Tejeda-Dominguez F, Lizardo-Thiebaud MJ, Mendez-Guerrero O, Gamboa-Dominguez A, Aguilar-Salinas CA, Huang CA, Kershenobich D, Bataller R, Torre A, Navarro-Alvarez N. Galectin-3 is overexpressed in advanced cirrhosis and predicts post-liver transplant infectious complications. Liver Int. 2022 Oct;42(10):2260-2273. PubMed PMID: 35635536
• Shah JA, Patel MS, Elias N, Navarro-Alvarez N, Rosales I, Wilkinson RA, Louras NJ, Hertl M, Fishman JA, Colvin RB, Cosimi AB, Markmann JF, Sachs DH, Vagefi PA. Prolonged Survival Following Pig-to-Primate Liver Xenotransplantation Utilizing Exogenous Coagulation Factors and Costimulation Blockade. Am J Transplant. 2017 Aug;17(8):2178-2185. PubMed PMID: 28489305
• Limon-de la Rosa N, Cervantes-Alvarez E, Méndez-Guerrero O, Gutierrez-Gallardo MA, Kershenobich D, Navarro-Alvarez N. Time-Dependent Changes of Laboratory Parameters as Independent Predictors of All-Cause Mortality in COVID-19 Patients. Biology (Basel). 2022 Apr 11;11(4). PubMed PMID: 35453779
• Cervantes-Alvarez E, la Rosa NL, la Mora MS, Valdez-Sandoval P, Palacios-Jimenez M, Rodriguez-Alvarez F, Vera-Maldonado BI, Aguirre-Aguilar E, Escobar-Valderrama JM, Alanis-Mendizabal J, Méndez-Guerrero O, Tejeda-Dominguez F, Torres-Ruíz J, Gómez-Martín D, Colborn KL, Kershenobich D, Huang CA, Navarro-Alvarez N. Galectin-3 as a potential prognostic biomarker of severe COVID-19 in SARS-CoV-2 infected patients. Sci Rep. 2022 Feb 3;12(1):1856. PubMed PMID: 35115644
• Limon-De La Rosa N, Cervantes-Alvarez E, Navarro-Alvarez N. Increased Hepatic Expression of SARS-CoV-2 Entry Points and Proinflammatory Cytokines in Cirrhosis. Clin Gastroenterol Hepatol. 2022 Jan;20(1):239-241.e3. PubMed PMID: 34481957
• JesusRuiz-Manriquez, AntonioOlivas-Martinez, Luis CarlosChávez-García, AlfonsoFernández-Ramírez, CarlosMoctezuma-Velazquez, EricKauffman-Ortega, GracielaCastro-Narro, FranciscoAstudillo-García, Ivonne Escalona-Nandez, Carlos A.Aguilar-Salinas, NaluNavarro-Alvarez, AldoTorre Prevalence of Metabolic-associated Fatty Liver Disease in Mexico and Development of a Screening Tool: The MAFLD-S Score. Gastro Hep Advances Volume 1, Issue 3, 2022, Pages 352-358 https://doi.org/10.1016/j.gastha.2021.12.011
• Jiang F, He J, Navarro-Alvarez N, Xu J, Li X, Li P, Wu W. Correction: Elongation Factor Tu and Heat Shock Protein 70 Are Membrane-Associated Proteins from Mycoplasma ovipneumoniae Capable of Inducing Strong Immune Response in Mice. PLoS One. 2017;12(12):e0189562. PubMed PMID: 29216313
• Shah JA, Navarro-Alvarez N, DeFazio M, Rosales IA, Elias N, Yeh H, Colvin RB, Cosimi AB, Markmann JF, Hertl M, Sachs DH, Vagefi PA. A Bridge to Somewhere: 25-day Survival After Pig-to-Baboon Liver Xenotransplantation. Ann Surg. 2016 Jun;263(6):1069-71. PubMed PMID: 26825261
• Yoeli D, Mack CL, Luo Y, Chaidez A, De La Rosa NL, Wang Z, Cervantes-Alvarez E, Huang CA, Navarro-Alvarez N. Galectin-3 in biliary atresia and other pediatric cholestatic liver diseases. Hepatol Res. 2023 Nov 11. [Epub ahead of print] PubMed PMID: 37950561
• Navarro-Alvarez N, Shah JA, Zhu A, Ligocka J, Yeh H, Elias N, Rosales I, Colvin R, Cosimi AB, Markmann JF, Hertl M, Sachs DH, Vagefi PA. The Effects of Exogenous Administration of Human Coagulation Factors Following Pig-to-Baboon Liver Xenotransplantation. Am J Transplant. 2016 Jun;16(6):1715-1725. PubMed PMID: 26613235
• Torre A, Cisneros-Garza LE, Castillo-Barradas M, Navarro-Alvarez N, Sandoval-Salas R, González-Huezo MS, Pérez-Hernández JL, Méndez-Guerrero O, Ruiz-Manríquez JA, Trejo-Estrada R, Chavez-Tapia NC, Solís-Gasca LC, Moctezuma-Velázquez C, Aguirre-Valádez J, Flores-Calderón J, Higuera-de-la-Tijera F, García-Juárez I, Canedo-Castillo NA, Malé-Velázquez R, Montalvo-Gordon I, Vilatobá M, Márquez-Guillén E, Córdova-Gallardo J, Flores-García NC, Miranda-Zazueta G, Martínez-Saldívar BI, Páez-Zayas VM, Muñoz-Espinosa LE, Solís-Galindo FA. Consensus document on acute-on-chronic liver failure (ACLF) established by the Mexican Association of Hepatology. Ann Hepatol. 2023 Jul 22;28(6):101140. [Epub ahead of print] PubMed PMID: 37482299
• Xu Y, Navarro-Alvarez N, Yang C, Markmann JF, Dong J, Yeh H. A reliable scoring system after major liver resection in mice. J Surg Res. 2016 Jul;204(1):75-82. PubMed PMID: 27451871
• Yoeli D, Mack CL, Navarro-Alvarez N. Role of galectin-3 in the pathogenesis and progression of biliary atresia. Clin Liver Dis (Hoboken). 2022 Nov;20(5):170-174. PubMed PMID: 36447904
• Liu WH, Ren LN, Wang T, Navarro-Alvarez N, Tang LJ. The Involving Roles of Intrahepatic and Extrahepatic Stem/Progenitor Cells (SPCs) to Liver Regeneration. Int J Biol Sci. 2016;12(8):954-63. PubMed PMID: 27489499
• Jiang F, He J, Navarro-Alvarez N, Xu J, Li X, Li P, Wu W. Elongation Factor Tu and Heat Shock Protein 70 Are Membrane-Associated Proteins from Mycoplasma ovipneumoniae Capable of Inducing Strong Immune Response in Mice. PLoS One. 2016;11(8):e0161170. PubMed PMID: 27537186
• Wang Z, Navarro-Alvarez N, Shah JA, Zhang H, Huang Q, Zheng Q, Madsen JC, Sachs DH, Huang CA, Wang Z. Porcine Treg depletion with a novel diphtheria toxin-based anti-human CCR4 immunotoxin. Vet Immunol Immunopathol. 2016 Dec;182:150-158. PubMed PMID: 27863545
• Navarro Alvarez N, Zhu A, Arellano RS, Randolph MA, Duggan M, Scott Arn J, Huang CA, Sachs DH, Vagefi PA. Postnatal xenogeneic B-cell tolerance in swine following in utero intraportal antigen exposure. Xenotransplantation. 2015 Sep-Oct;22(5):368-78. PubMed PMID: 26314946
• Liu WH, Ren LN, Wang X, Wang T, Zhang N, Gao Y, Luo H, Navarro-Alvarez N, Tang LJ. Combination of exosomes and circulating microRNAs may serve as a promising tumor marker complementary to alpha-fetoprotein for early-stage hepatocellular carcinoma diagnosis in rats. J Cancer Res Clin Oncol. 2015 Oct;141(10):1767-78. PubMed PMID: 25724413
• Meier RPH, Navarro-Alvarez N, Morel P, Schuurman HJ, Strom S, Bühler LH. Current status of hepatocyte xenotransplantation. Int J Surg. 2015 Nov;23(Pt B):273-279. PubMed PMID: 26361861
• Yeh H, Machaidze Z, Wamala I, Fraser JW, Navarro-Alvarez N, Kim K, Schuetz C, Shi S, Zhu A, Hertl M, Elias N, Farkash EA, Vagefi PA, Varma M, Smith RN, Robson SC, Van Cott EM, Sachs DH, Markmann JF. Increased transfusion-free survival following auxiliary pig liver xenotransplantation. Xenotransplantation. 2014 Sep-Oct;21(5):454-64. PubMed PMID: 25130043
• Navarro-Alvarez N, Yang YG. Lack of CD47 on donor hepatocytes promotes innate immune cell activation and graft loss: a potential barrier to hepatocyte xenotransplantation. Cell Transplant. 2014 Mar;23(3):345-54. PubMed PMID: 23394628
• Navarro-Alvarez N, Yang YG. CD47: a new player in phagocytosis and xenograft rejection. Cell Mol Immunol. 2011 Jul;8(4):285-8. PubMed PMID: 21258362
• Yagi H, Soto-Gutierrez A, Navarro-Alvarez N, Nahmias Y, Goldwasser Y, Kitagawa Y, Tilles AW, Tompkins RG, Parekkadan B, Yarmush ML. Reactive bone marrow stromal cells attenuate systemic inflammation via sTNFR1. Mol Ther. 2010 Oct;18(10):1857-64. PubMed PMID: 20664529
• Navarro-Alvarez N, Soto-Gutierrez A, Chen Y, Caballero-Corbalan J, Hassan W, Kobayashi S, Kondo Y, Iwamuro M, Yamamoto K, Kondo E, Tanaka N, Fox IJ, Kobayashi N. Intramuscular transplantation of engineered hepatic tissue constructs corrects acute and chronic liver failure in mice. J Hepatol. 2010 Feb;52(2):211-9. PubMed PMID: 20022655
• Navarro-Alvarez N, Soto-Gutierrez A, Kobayashi N. Hepatic stem cells and liver development. Methods Mol Biol. 2010;640:181-236. PubMed PMID: 20645053
• Navarro-Alvarez N, Kondo E, Kawamoto H, Hassan W, Yuasa T, Kubota Y, Seita M, Nakahara H, Hayashi T, Nishikawa Y, Hassan RA, Javed SM, Noguchi H, Matsumoto S, Nakaji S, Tanaka N, Kobayashi N, Soto-Gutierrez A. Isolation and propagation of a human CD133(-) colon tumor-derived cell line with tumorigenic and angiogenic properties. Cell Transplant. 2010;19(6):865-77. PubMed PMID: 20587145
• Soto-Gutierrez A, Navarro-Alvarez N, Yagi H, Nahmias Y, Yarmush ML, Kobayashi N. Engineering of an hepatic organoid to develop liver assist devices. Cell Transplant. 2010;19(6):815-22. PubMed PMID: 20573303
• Yamamoto T, Navarro-Alvarez N, Soto-Gutierrez A, Yuasa T, Iwamuro M, Kubota Y, Seita M, Kawamoto H, Javed SM, Kondo E, Noguchi H, Kobayashi S, Nakaji S, Kobayashi N. Treatment of acute liver failure in mice by hepatocyte xenotransplantation. Cell Transplant. 2010;19(6):799-806. PubMed PMID: 20573299
• Soto-Gutierrez A, Yagi H, Uygun BE, Navarro-Alvarez N, Uygun K, Kobayashi N, Yang YG, Yarmush ML. Cell delivery: from cell transplantation to organ engineering. Cell Transplant. 2010;19(6):655-65. PubMed PMID: 20525441
• Navarro-Alvarez N, Soto-Gutierrez A, Kobayashi N. Stem cell research and therapy for liver disease. Curr Stem Cell Res Ther. 2009 May;4(2):141-6. PubMed PMID: 19442198
• Basma H, Soto-Gutiérrez A, Yannam GR, Liu L, Ito R, Yamamoto T, Ellis E, Carson SD, Sato S, Chen Y, Muirhead D, Navarro-Alvarez N, Wong RJ, Roy-Chowdhury J, Platt JL, Mercer DF, Miller JD, Strom SC, Kobayashi N, Fox IJ. Differentiation and transplantation of human embryonic stem cell-derived hepatocytes. Gastroenterology. 2009 Mar;136(3):990-9. PubMed PMID: 19026649
• Soto-Gutierrez A, Navarro-Alvarez N, Yagi H, Yarmush ML. Stem cells for liver repopulation. Curr Opin Organ Transplant. 2009 Dec;14(6):667-73. PubMed PMID: 19779345
• Yuasa T, Rivas-Carrillo JD, Navarro-Alvarez N, Soto-Gutierrez A, Kubota Y, Tabata Y, Okitsu T, Noguchi H, Matsumoto S, Nakaji S, Tanaka N, Kobayashi N. Neovascularization induced around an artificial device implanted in the abdomen by the use of gelatinized fibroblast growth factor 2. Cell Transplant. 2009;18(5):683-8. PubMed PMID: 19775531
• Navarro-Alvarez N, Soto-Gutierrez A, Yuasa T, Yamatsuji T, Shirakawa Y, Nagasaka T, Sheng SD, Javed MS, Tanaka N, Kobayashi N. Long-Term Culture of Japanese Human Embryonic Stem Cells in Feeder-Free Conditions. Cell Transplant. 2008 Jan Feb;17(1-2):27-33. PubMed PMID: 28858592
• Soto-Gutierrez A, Navarro-Alvarez N, Caballero-Corbalan J, Tanaka N, Kobayashi N. Endoderm induction for hepatic and pancreatic differentiation of ES cells. Acta Med Okayama. 2008 Apr;62(2):63-8. PubMed PMID: 18464881
• Yuasa T, Yamamoto T, Rivas-Carrillo JD, Chen Y, Navarro-Alvarez N, Soto-Guiterrez A, Noguchi H, Matsumoto S, Tanaka N, Kobayashi N. Laparoscopy-assisted creation of a liver failure model in pigs. Cell Transplant. 2008;17(1-2):187-93. PubMed PMID: 18468249
• Navarro-Alvarez N, Rivas-Carrillo JD, Soto-Gutierrez A, Yuasa T, Okitsu T, Noguchi H, Matsumoto S, Takei J, Tanaka N, Kobayashi N. Reestablishment of microenvironment is necessary to maintain in vitro and in vivo human islet function. Cell Transplant. 2008;17(1-2):111-9. PubMed PMID: 18468241
• Navarro-Alvarez N, Soto-Gutierrez A, Yuasa T, Yamatsuji T, Shirakawa Y, Nagasaka T, Sun SD, Javed MS, Tanaka N, Kobayashi N. Long-term culture of Japanese human embryonic stem cells in feeder-free conditions. Cell Transplant. 2008;17(1-2):27-33. PubMed PMID: 18468232
• Kobayashi N, Navarro-Alvarez N, Soto-Gutierrez A, Kawamoto H, Kondo Y, Yamatsuji T, Shirakawa Y, Naomoto Y, Tanaka N. Cancer stem cell research: current situation and problems. Cell Transplant. 2008;17(1-2):19-25. PubMed PMID: 18468231
• Soto-Gutierrez A, Basma H, Navarro-Alvarez N, Uygun BE, Yarmush ML, Kobayashi N, Fox IJ. Differentiating stem cells into liver. Biotechnol Genet Eng Rev. 2008;25:149-63. PubMed PMID: 21412354
• Rivas-Carrillo JD, Soto-Gutierrez A, Navarro-Alvarez N, Noguchi H, Okitsu T, Chen Y, Yuasa T, Tanaka K, Narushima M, Miki A, Misawa H, Tabata Y, Jun HS, Matsumoto S, Fox IJ, Tanaka N, Kobayashi N. Cell-permeable pentapeptide V5 inhibits apoptosis and enhances insulin secretion, allowing experimental single-donor islet transplantation in mice. Diabetes. 2007 May;56(5):1259-67. PubMed PMID: 17287463
• Totsugawa T, Yong C, Rivas-Carrillo JD, Soto-Gutierrez A, Navarro-Alvarez N, Noguchi H, Okitsu T, Westerman KA, Kohara M, Reth M, Tanaka N, Leboulch P, Kobayashi N. Survival of liver failure pigs by transplantation of reversibly immortalized human hepatocytes with Tamoxifen-mediated self-recombination. J Hepatol. 2007 Jul;47(1):74-82. PubMed PMID: 17434229
• Soto-Gutierrez A, Navarro-Alvarez N, Rivas-Carrillo JD, Tanaka K, Chen Y, Misawa H, Okitsu T, Noguchi H, Tanaka N, Kobayashi N. Construction and transplantation of an engineered hepatic tissue using a polyaminourethane-coated nonwoven polytetrafluoroethylene fabric. Transplantation. 2007 Jan 27;83(2):129-37. PubMed PMID: 17264808
• Soto-Gutiérrez A, Navarro-Alvarez N, Zhao D, Rivas-Carrillo JD, Lebkowski J, Tanaka N, Fox IJ, Kobayashi N. Differentiation of mouse embryonic stem cells to hepatocyte-like cells by co-culture with human liver nonparenchymal cell lines. Nat Protoc. 2007;2(2):347-56. PubMed PMID: 17406596
• Soto-Gutiérrez A, Kobayashi N, Rivas-Carrillo JD, Navarro-Alvarez N, Zhao D, Okitsu T, Noguchi H, Basma H, Tabata Y, Chen Y, Tanaka K, Narushima M, Miki A, Ueda T, Jun HS, Yoon JW, Lebkowski J, Tanaka N, Fox IJ. Reversal of mouse hepatic failure using an implanted liver-assist device containing ES cell-derived hepatocytes. Nat Biotechnol. 2006 Nov;24(11):1412-9. PubMed PMID: 17086173
• Ikeda H, Kobayashi N, Tanaka Y, Nakaji S, Yong C, Okitsu T, Oshita M, Matsumoto S, Noguchi H, Narushima M, Tanaka K, Miki A, Rivas-Carrillo JD, Soto-Gutierrez A, Navarro-Alvarez N, Tanaka K, Jun HS, Tanaka N, Yoon JW. A newly developed bioartificial pancreas successfully controls blood glucose in totally pancreatectomized diabetic pigs. Tissue Eng. 2006 Jul;12(7):1799-809. PubMed PMID: 16889510
• Tanaka K, Kobayashi N, Gutierrez AS, Rivas-Carrillo JD, Navarro-Alvarez N, Chen Y, Narushima M, Miki A, Okitsu T, Noguchi H, Tanaka N. Prolonged survival of mice with acute liver failure with transplantation of monkey hepatocytes cultured with an antiapoptotic pentapeptide V5. Transplantation. 2006 Feb 15;81(3):427-37. PubMed PMID: 16477231
• Miki A, Narushima M, Okitsu T, Takeno Y, Soto-Gutierrez A, Rivas-Carrillo JD, Navarro-Alvarez N, Chen Y, Tanaka K, Noguchi H, Matsumoto S, Kohara M, Lakey JRT, Kobayashi E, Tanaka N, Kobayashi N. Maintenance of Mouse, Rat, and Pig Pancreatic Islet Functions by Coculture with Human Islet-Derived Fibroblasts. Cell Transplant. 2006 Apr;15(4):325-334. PubMed PMID: 28863744
• Rivas-Carrillo JD, Navarro-Alvarez N, Soto-Gutierrez A, Okitsu T, Chen Y, Tabata Y, Misawa H, Noguchi H, Matsumoto S, Tanaka N, Kobayashi N. Amelioration of diabetes in mice after single-donor islet transplantation using the controlled release of gelatinized FGF-2. Cell Transplant. 2006;15(10):939-44. PubMed PMID: 17299999
• Misawa H, Kobayashi N, Soto-Gutierrez A, Chen Y, Yoshida A, Rivas-Carrillo JD, Navarro-Alvarez N, Tanaka K, Miki A, Takei J, Ueda T, Tanaka M, Endo H, Tanaka N, Ozaki T. PuraMatrix facilitates bone regeneration in bone defects of calvaria in mice. Cell Transplant. 2006;15(10):903-10. PubMed PMID: 17299995
• Miki A, Rivas-Carrillo JD, Navarro-Alvarez N, Soto-Gutierrez A, Chen Y, Tanaka K, Narushima M, Tabata Y, Okitsu T, Noguchi H, Matsumoto S, Tanaka N, Kobayashi N. Maintenance of neovascularization at the implantation site of an artificial device by bFGF and endothelial cell transplant. Cell Transplant. 2006;15(10):893-901. PubMed PMID: 17299994
• Chen Y, Soto-Gutierrez A, Navarro-Alvarez N, Rivas-Carrillo JD, Yamatsuji T, Shirakawa Y, Tanaka N, Basma H, Fox IJ, Kobayashi N. Instant hepatic differentiation of human embryonic stem cells using activin A and a deleted variant of HGF. Cell Transplant. 2006;15(10):865-71. PubMed PMID: 17299990
• Navarro-Alvarez N, Soto-Gutierrez A, Rivas-Carrillo JD, Chen Y, Yamamoto T, Yuasa T, Misawa H, Takei J, Tanaka N, Kobayashi N. Self-assembling peptide nanofiber as a novel culture system for isolated porcine hepatocytes. Cell Transplant. 2006;15(10):921-7. PubMed PMID: 17299997
• Tanaka K, Soto-Gutierrez A, Navarro-Alvarez N, Rivas-Carrillo JD, Jun HS, Kobayashi N. Functional hepatocyte culture and its application to cell therapies. Cell Transplant. 2006;15(10):855-64. PubMed PMID: 17299989
• Soto-Gutierrez A, Navarro-Alvarez N, Rivas-Carrillo JD, Chen Y, Yamatsuji T, Tanaka N, Kobayashi N. Differentiation of human embryonic stem cells to hepatocytes using deleted variant of HGF and poly-amino-urethane-coated nonwoven polytetrafluoroethylene fabric. Cell Transplant. 2006;15(4):335-41. PubMed PMID: 16898227
• Miki A, Narushima M, Okitsu T, Takeno Y, Soto-Gutierrez A, Rivas-Carrillo JD, Navarro-Alvarez N, Chen Y, Tanaka K, Noguchi H, Matsumoto S, Kohara M, Lakey JR, Kobayashi E, Tanaka N, Kobayashi N. Maintenance of mouse, rat, and pig pancreatic islet functions by coculture with human islet-derived fibroblasts. Cell Transplant. 2006;15(4):325-34. PubMed PMID: 16898226
• Narushima M, Kobayashi N, Okitsu T, Tanaka Y, Li SA, Chen Y, Miki A, Tanaka K, Nakaji S, Takei K, Gutierrez AS, Rivas-Carrillo JD, Navarro-Alvarez N, Jun HS, Westerman KA, Noguchi H, Lakey JR, Leboulch P, Tanaka N, Yoon JW. A human beta-cell line for transplantation therapy to control type 1 diabetes. Nat Biotechnol. 2005 Oct;23(10):1274-82. PubMed PMID: 16186810
• Chen Y, Kobayashi N, Suzuki S, Soto-Gutierrez A, Rivas-Carrillo JD, Tanaka K, Navarro-Alvarez N, Fukazawa T, Narushima M, Miki A, Okitsu T, Amemiya H, Tanaka N. Transplantation of human hepatocytes cultured with deleted variant of hepatocyte growth factor prolongs the survival of mice with acute liver failure. Transplantation. 2005 May 27;79(10):1378-85. PubMed PMID: 15912107
• Kobayashi N, Rivas-Carrillo JD, Soto-Gutierrez A, Fukazawa T, Chen Y, Navarro-Alvarez N, Tanaka N. Gene delivery to embryonic stem cells. Birth Defects Res C Embryo Today. 2005 Mar;75(1):10-8. PubMed PMID: 15838919