Junxiao Hu, PhD
Assistant Professor, Pediatrics-Endocrinology

Publications

• Bang, T. J., Hu, J., Patil, T., Barón, A. E., Gao, D., Yang, J. C. H., ... & Camidge, D. R. (2022). The Effect of Intrathoracic Lesion Location on Initial Tyrosine Kinase Inhibitor Response in Advanced Oncogene-Addicted Non-Small Cell Lung Cancer: A Comparison Between RECIST 1.1 and a Novel Method of Response Assessment (MAX). Clinical Lung Cancer.
• Nathenson MJ, Hu J, Ratan R, Somaiah N, Hsu R, DeMaria PJ, Catoe HW, Pang A, Subhawong TK, Amini B, Sweet K, Feister K, Malik K, Jagannathan J, Braschi-Amirfarzan M, Sheren J, Caldas Y, Moreno Tellez C, Rosenberg AE, Lazar AJ, Maki RG, Benedetto P, Cohen J, Trent JC, Ravi V, Patel S, Wilky BA. Systemic Chemotherapies Retain Antitumor Activity in Desmoid Tumors Independent of Specific Mutations in CTNNB1 or APC: A Multi-institutional Retrospective Study. Clin Cancer Res. 2022 Sep 15;28(18):4092-4104. PubMed PMID: 35180772
• Gilbert, D., Hu, J., Kessler, E. R., & Lam, E. T. (2022). COVID-19 vaccine and incidence of severe immune-mediated adverse events in patients with renal cell carcinoma (RCC) on checkpoint inhibitor immunotherapy (CPI).
• Sheneman, D., Hu, J., Das, S., & Lieu, C. H. (2022). Chemotherapy delivery in early-onset colorectal cancer is impacted by urban versus rural settings in Colorado.
• Kolb JM, Hu J, DeSanto K, Gao D, Singh S, Imperiale T, Lieberman DA, Boland CR, Patel SG. Early-Age Onset Colorectal Neoplasia in Average-Risk Individuals Undergoing Screening Colonoscopy: A Systematic Review and Meta-Analysis. Gastroenterology. 2021 Oct;161(4):1145-1155.e12. PubMed PMID: 34119517
• Goldstein NB, Steel A, Barbulescu CC, Koster MI, Wright MJ, Jones KL, Gao B, Ward B, Woessner B, Trottier Z, Pakieser J, Hu J, Lambert KA, Shellman YG, Fujita M, Robinson WA, Roop DR, Norris DA, Birlea SA. Melanocyte Precursors in the Hair Follicle Bulge of Repigmented Vitiligo Skin Are Controlled by RHO-GTPase, KCTD10, and CTNNB1 Signaling. J Invest Dermatol. 2021 Mar;141(3):638-647.e13. PubMed PMID: 32800877
• Duarte C, Beuselinck B, Weise N, Dizman N, Collier K, Li H, Martinez Chanza N, Elias R, Rose TL, Brugarolas J, Agarwal N. Treatment outcomes in renal cell carcinoma patients with metastases to the pancreas and other sites.
• Lentz RW, Friedrich T, Hu J, Leal AD, Kim SS, Davis SL, Purcell T, Messersmith WA, Lieu CH. Tissue tumor mutational burden (TMB) as a biomarker of efficacy with immune checkpoint inhibitors (ICI) in metastatic gastrointestinal (mGI) cancers.
• Friedrich T, Hu J, Lentz RW, Leal AD, Kim SS, Messersmith WA, Davis SL, McCarter M, Ahrendt SA, Gleisner A, Lieu CH. Utility of chemotherapy given before and/or after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for appendiceal adenocarcinoma with peritoneal metastases.
• Kolb JM, Hu J, DeSanto K, Gao D, Singh S, Imperiale T, Lieberman DA, Boland CR, Patel SG. Early-Age Onset Colorectal Neoplasia in Average-Risk Individuals Undergoing Screening Colonoscopy: A Systematic Review and Meta-Analysis. Gastroenterology. 2021 Oct;161(4):1145-1155.e12. PubMed PMID: 34119517
• Goldstein NB, Steel A, Barbulescu CC, Koster MI, Wright MJ, Jones KL, Gao B, Ward B, Woessner B, Trottier Z, Pakieser J, Hu J, Lambert KA, Shellman YG, Fujita M, Robinson WA, Roop DR, Norris DA, Birlea SA. Melanocyte Precursors in the Hair Follicle Bulge of Repigmented Vitiligo Skin Are Controlled by RHO-GTPase, KCTD10, and CTNNB1 Signaling. J Invest Dermatol. 2021 Mar;141(3):638-647.e13. PubMed PMID: 32800877
• Kessler, E. R., Hu, J., Srivastava, G., Kemme, D. J., Iruku, P., Rana, V., ... & Lam, E. T. (2021). Phase I/II trial of pembrolizumab and cabozantinib in the treatment of metastatic renal cell carcinoma (mRCC).
• Lentz, R. W., Friedrich, T., Hu, J., Leal, A. D., Kim, S. S., Davis, S. L., ... & Lieu, C. H. (2021). Tissue tumor mutational burden (TMB) as a biomarker of efficacy with immune checkpoint inhibitors (ICI) in metastatic gastrointestinal (mGI) cancers.
• Duarte, C., Beuselinck, B., Weise, N., Dizman, N., Collier, K., Li, H., ... & Lam, E. T. (2021). Treatment outcomes in renal cell carcinoma patients with metastases to the pancreas and other sites.
• Patil, T., Nie, Y., Hu, J., Schenk, E. L., Pacheco, J. M., Purcell, W. T., ... & Camidge, D. R. (2021). Duration of pemetrexed maintenance therapy with or without pembrolizumab is associated with risk of renal toxicity in patients with metastatic nonsquamous NSCLC.
• Friedrich, T., Hu, J., Lentz, R. W., Leal, A. D., Kim, S. S., Messersmith, W. A., ... & Lieu, C. H. (2021). Utility of chemotherapy given before and/or after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for appendiceal adenocarcinoma with peritoneal metastases.
• Eule, C., Hu, J., Al-Saadi, S., Collier, K., Boland, P. J., McKay, R. R., ... & Lam, E. T. (2022). Outcomes of second-line therapies in patients with metastatic de novo small cell prostate cancer (SCPC) and treatment-emergent neuroendocrine prostate cancer (tNEPC).
• Jordan K, Sikora MJ, Slansky JE, Minic A, Richer JK, Moroney MR, Hu J, Wolsky RJ, Watson ZL, Yamamoto TM, Costello JC, Clauset A, Behbakht K, Kumar TR, Bitler BG. The capacity of the ovarian cancer tumor microenvironment to integrate inflammation signaling conveys a shorter disease-free interval. Clin Cancer Res. 2020 Sep 14. [Epub ahead of print] PubMed PMID: 32928797
• Goldstein NB, Steel A, Barbulescu CC, Koster MI, Wright MJ, Jones KL, Gao B, Ward B, Woessner B, Trottier Z, Pakieser J, Hu J, Lambert KA, Shellman YG, Fujita M, Robinson WA, Roop DR, Norris DA, Birlea SA. MELANOCYTE PRECURSORS IN THE HAIR FOLLICLE BULGE OF REPIGMENTED VITILIGO SKIN ARE CONTROLLED BY RHO-GTPase, KCTD10 AND CTNNB1 SIGNALING. J Invest Dermatol. 2020 Aug 12. [Epub ahead of print] PubMed PMID: 32800877
• Patel SG, Ahnen DJ, Gumidyala A, Espinoza J, Nicklawsky A, Hu J, Smith D, Lowery J, Austin G, Cockburn M. Poor Knowledge of Personal and Familial Colorectal Cancer Risk and Screening Recommendations Associated with Advanced Colorectal Polyps. Dig Dis Sci. 2020 Sep;65(9):2542-2550. PubMed PMID: 32144601
• Borges VF, Hu J, Young C, Maggard J, Parris HJ, Gao D, Lyons TR. Semaphorin 7a is a biomarker for recurrence in postpartum breast cancer. NPJ Breast Cancer. 2020;6:56. PubMed PMID: 33088913
• Hu J, Blatchford PJ, Goldenberg NA, Kittelson JM. Group sequential designs for clinical trials with bivariate endpoints. Stat Med. 2020 Nov 20;39(26):3823-3839. PubMed PMID: 33048360
• Borges VF, Hu J, Young C, Maggard J, Parris HJ, Gao D, Lyons TR. Semaphorin 7a is a biomarker for recurrence in postpartum breast cancer. NPJ Breast Cancer. 2020;6:56. PubMed PMID: 33088913
• Hu J, Blatchford PJ, Goldenberg NA, Kittelson JM. Group sequential designs for clinical trials with bivariate endpoints. Stat Med. 2020 Nov 20;39(26):3823-3839. PubMed PMID: 33048360
• Jordan KR, Sikora MJ, Slansky JE, Minic A, Richer JK, Moroney MR, Hu J, Wolsky RJ, Watson ZL, Yamamoto TM, Costello JC, Clauset A, Behbakht K, Kumar TR, Bitler BG. The Capacity of the Ovarian Cancer Tumor Microenvironment to Integrate Inflammation Signaling Conveys a Shorter Disease-free Interval. Clin Cancer Res. 2020 Dec 1;26(23):6362-6373. PubMed PMID: 32928797
• Patel SG, Ahnen DJ, Gumidyala A, Espinoza J, Nicklawsky A, Hu J, Smith D, Lowery J, Austin G, Cockburn M. Poor Knowledge of Personal and Familial Colorectal Cancer Risk and Screening Recommendations Associated with Advanced Colorectal Polyps. Dig Dis Sci. 2020 Sep;65(9):2542-2550. PubMed PMID: 32144601
• Duarte C, Martinez Chanza N, Collier K, Dizman N, Rathi N, McKay RR, Panian J, Narayan V, Carneiro BA, Mega AE, Hu J. Outcomes of patients with pancreatic-only oligometastatic renal cell carcinoma (RCC).
• Patil T, Nie Y, Hu J, Schenk EL, Pacheco JM, Purcell WT, Bunn PA, Camidge DR. Duration of pemetrexed maintenance therapy with or without pembrolizumab is associated with risk of renal toxicity in patients with metastatic nonsquamous NSCLC.
• Kessler ER, Hu J, Srivastava G, Kemme DJ, Iruku P, Rana V, Schuster SR, Amirault M, Callihan E, Flaig TW, Lam ET. Phase I/II trial of pembrolizumab and cabozantinib in the treatment of metastatic renal cell carcinoma (mRCC).
• Borges, V. F., Hu, J., Young, C., Maggard, J., Parris, H. J., Gao, D., & Lyons, T. R. (2020). Semaphorin 7a is a biomarker for recurrence in postpartum breast cancer. NPJ breast cancer, 6(1), 1-6.
• Hu, J., Blatchford, P. J., Goldenberg, N. A., & Kittelson, J. M. (2020). Group sequential designs for clinical trials with bivariate endpoints. Statistics in Medicine, 39(26), 3823-3839.
• Patel, S. G., Ahnen, D. J., Gumidyala, A., Espinoza, J., Nicklawsky, A., Hu, J., ... & Cockburn, M. (2020). Poor knowledge of personal and familial colorectal cancer risk and screening recommendations associated with advanced colorectal polyps. Digestive diseases and sciences, 65(9), 2542-2550.
• Jordan, K. R., Sikora, M. J., Slansky, J. E., Minic, A., Richer, J. K., Moroney, M. R., ... & Bitler, B. G. (2020). The Capacity of the Ovarian Cancer Tumor Microenvironment to Integrate Inflammation Signaling Conveys a Shorter Disease-free IntervalTherapy-induced Remodeling of the Tumor Microenvironment. Clinical Cancer Research, 26(23), 6362-6373.
• Duarte C, Martinez Chanza N, Collier K, Dizman N, Rathi N, McKay RR, Panian J, Narayan V, Carneiro BA, Mega AE, Hu J. Outcomes of patients with pancreatic-only oligometastatic renal cell carcinoma (RCC).
• Hu, J. (2019). Design and Application of Sequential Clinical Trials With Bivariate Outcomes. University of Colorado Denver, Anschutz Medical Campus.
• Reinhold, D., Morrow, J. D., Jacobson, S., Hu, J., Ringel, B., Seibold, M. A., ... & Bowler, R. P. (2017). Meta-analysis of peripheral blood gene expression modules for COPD phenotypes. PloS one, 12(10), e0185682.