Andrew Novick, MD, PhD

Assistant Professor, Psychiatry-Other CI Services


FacultyPhoto
Medical School
  • MD, Sanford School of Medicine The University of South Dakota (2015)
Graduate School
  • PhD, University of South Dakota, The (2015)
Undergraduate School
  • BS, University of the Sciences in Philadelphia (PA) (2008)
Residency
  • Brown University (Butler Hospital) Program, Psychiatry (2019)
Languages
English
Department
Psychiatry-Other CI Services

Professional Titles

  • Medical Director, CU Esketamine Program
  • Reproductive Psychiatrist, Colorado Women's Behavioral Health and Wellness

Recognitions

  • NNCI Scholar, National Neuroscience Curriculum Initiative (2018)
  • Martin B. Keller Award for Most Outstanding Graduating Resident, Department of Psychiatry, Brown University (2019)
  • Travel Award Fellowship, Society of Biological Psychiatry (2022)
  • Emerging Scholar Travel Award, National Network of Depression Centers (2022)
  • American College of Neuropsychopharmacology Travel Award, National Network of Depression Centers (2024)

Research Interests

My research interests are divided into two main areas: 1) Understanding the effects of sex steroids on the brain 2) Evaluating novel drug therapies for psychiatric disorders, specifically psychedelics. I am currently testing the effects of an oral birth control pill on brain functions related to mood, motivation, and pleasure. I am also principal investigator on a study evaluating the effects of the psychedelic drug, psilocybin, in treatment-resistant Major Depressive Disorder.

Publications

  • Vijayaraghavan S, Ross DA, Novick AM. Under the Microscope: Nerve Glue and the Evolution of Psychiatric Neuroscience. Biol Psychiatry. 2024 Nov 1;96(9):e11-e13. PubMed PMID: 39357969
  • Page CE, Epperson CN, Novick AM, Duffy KA, Thompson SM. Beyond the serotonin deficit hypothesis: communicating a neuroplasticity framework of major depressive disorder. Mol Psychiatry. 2024 Dec;29(12):3802-3813. PubMed PMID: 38816586
  • Epperson CN, Nagle-Yang S, Novick AM. Reproductive Psychiatry: Postpartum Depression is Only the Tip of the Iceberg. Focus (Am Psychiatr Publ). 2024 Jan;22(1):1-2. PubMed PMID: 38694150
  • Haller HC, Moore SL, Green KK, Johnson RL, Sammel MD, Epperson CN, Novick AM. Harnessing technology to improve sleep in frontline healthcare workers: A pilot study of electronic noise-masking earbuds on subjective and objective sleep measures. Sci Prog. 2024 Apr-Jun;107(2):368504241242276. PubMed PMID: 38614463
  • Dodd K, Legget KT, Cornier MA, Novick AM, McHugo M, Berman BD, Lawful BP, Tregellas JR. Relationship between functional connectivity and weight-gain risk of antipsychotics in schizophrenia. Schizophr Res. 2024 May;267:173-181. PubMed PMID: 38552340
  • Danzig A, Novick AM, Chang WL, Ross DA. From Social Isolation to Social Justice: The Neuroscience of Solitary Confinement. Biol Psychiatry. 2024 Apr 1;95(7):e13-e15. PubMed PMID: 38479978
  • Kavanaugh BC, Parade S, Seifer R, McLaughlin NCR, Tirrell E, Festa EK, Oberman LM, Novick AM, Carpenter LL, Tyrka AR. Childhood stress, gender, and cognitive control: Midline theta power. J Psychiatr Res. 2024 Jan;169:298-306. PubMed PMID: 38070470
  • ElSayed MW, Novick AM, Cooper JJ, Ross DA. The Sweet Taste of Progress-The Evolving Role of Electroencephalography in Psychiatry. Biol Psychiatry. 2023 Apr 15;93(8):e21-e23. PubMed PMID: 36948760
  • Hantsoo L, Jagodnik KM, Novick AM, Baweja R, di Scalea TL, Ozerdem A, McGlade EC, Simeonova DI, Dekel S, Kornfield SL, Nazareth M, Weiss SJ. The role of the hypothalamic-pituitary-adrenal axis in depression across the female reproductive lifecycle: current knowledge and future directions. Front Endocrinol (Lausanne). 2023;14:1295261. PubMed PMID: 38149098
  • Metcalf CA, Duffy KA, Page CE, Novick AM. Cognitive Problems in Perimenopause: A Review of Recent Evidence. Curr Psychiatry Rep. 2023 Oct;25(10):501-511. PubMed PMID: 37755656
  • Kyzar EJ, Novick AM, Ross DA. The Hidden Side of Addiction: Allostatic Load, Health Disparities, and Opioids in the Time of COVID. Biol Psychiatry. 2023 Jun 15;93(12):e57-e59. PubMed PMID: 37257984
  • Novick AM, Stoddard J, Johnson RL, Duffy KA, Berkowitz L, Costa VD, Sammel MD, Epperson CN. Adverse childhood experiences and hormonal contraception: Interactive impact on sexual reward function. PLoS One. 2023;18(1):e0279764. PubMed PMID: 36649369
  • Novick AM, Duffy KA, Johnson RL, Sammel MD, Cao W, Strasser AA, Sofuoglu M, Kuzma A, Loughead J, Morrow AL, Epperson CN. Effect of progesterone administration in male and female smokers on nicotine withdrawal and neural response to smoking cues: role of progesterone conversion to allopregnanolone. Biol Sex Differ. 2022 Oct 23;13(1):60. PubMed PMID: 36274158
  • Lebin LG, Novick AM. Selective Serotonin Reuptake Inhibitors (SSRIs) in Pregnancy: An Updated Review on Risks to Mother, Fetus, and Child. Curr Psychiatry Rep. 2022 Nov;24(11):687-695. PubMed PMID: 36181572
  • Novick AM, Kwitowski M, Dempsey J, Cooke DL, Dempsey AG. Technology-Based Approaches for Supporting Perinatal Mental Health. Curr Psychiatry Rep. 2022 Sep;24(9):419-429. PubMed PMID: 35870062
  • Allsop AS, Chaudhry HW, Novick AM, Ross DA. Stepping Out of the Palace of Luxury: Mindfulness and Modern Psychiatry. Biol Psychiatry. 2022 Jul 15;92(2):e5-e7. PubMed PMID: 35772908
  • Novick AM, Duffy KA, Johnson RL, Sammel MD, Cao W, Strasser AA, Sofuoglu M, Kuzma A, Loughead J, Epperson CN. Progesterone Increases Nicotine Withdrawal and Anxiety in Male but Not Female Smokers During Brief Abstinence. Nicotine Tob Res. 2022 Nov 12;24(12):1898-1905. PubMed PMID: 35713950
  • Novick AM, Johnson RL, Lazorwitz A, Belyavskaya A, Berkowitz L, Norton A, Sammel MD, Epperson CN. Discontinuation of hormonal contraception due to changes in mood and decreases in sexual desire: the role of adverse childhood experiences. Eur J Contracept Reprod Health Care. 2022 Jun;27(3):212-220. PubMed PMID: 35133231
  • Metcalf CA, Johnson RL, Novick AM, Freeman EW, Sammel MD, Anthony LG, Epperson CN. Adverse childhood experiences interact with inflammation and menopause transition stage to predict verbal memory in women. Brain Behav Immun Health. 2022 Mar;20:100411. PubMed PMID: 35079709
  • Nagle-Yang SM, Debrunner SA, Favini A, Novick AM, Hasser C, Prakash C, Nathan M. Bipolar Disorder and Related Disorders. In: Hunter LA, Catapano LA, Nagle-Yang SM, Williams KE, Osbourne LM, editors. Textbook of Women’s Reproductive Mental Health. Washington, DC: American Psychiatric Association; 2022. p. 401–432.
  • Nagle-Yang SM, Friedman SH, Hasser C, Mulvihill A, Novick AM, Jones AK, Reed E, Sabhapathy S. Schizophrenia and Related Disorders. In: Hunter LA, Catapano LA, Nagle-Yang SM, Williams KE, Osbourne LM, editors. Textbook of Women’s Reproductive Mental Health. Washington, DC: American Psychiatric Association; 2022. p. 445–482.
  • Novick AM, Stoddard J, Johnson RL, Sammel MD, Berkowitz L, Epperson CN. Adapting psychiatric research in the age of COVID-19: role of online studies. BJPsych Open. 2021 Sep;7(5):e177. PubMed PMID: 34635873
  • Pettigrew JA, Novick AM. Hypoactive Sexual Desire Disorder in Women: Physiology, Assessment, Diagnosis, and Treatment. J Midwifery Womens Health. 2021 Nov;66(6):740-748. PubMed PMID: 34510696
  • Nagle Yang SM, DeBrunner SA, Favini A, Novick AM, Hasser C, Prakash C, Nathan M. Bipolar Disorder and Related Disorders. IN: Hunter LA, Capapano L, Nagle-Yang S, Williams KE, and Osbourne LM. Textbook of Women's Reproductive Mental Health. Washington DC: American Psychiatric Association Publishing; 2022. p401-432
  • Nagle-Yang SM, Friedman SH, Hasser C, Mulvihill A, Novick AM, Jones AK, Reed E, Sabhapathy S. Schizophrenia and Related DIsorders IN: Hunter LA, Capapano L, Nagle-Yang S, Williams KE, and Osbourne LM. Textbook of Women's Reproductive Mental Health. Washington DC: American Psychiatric Association Publishing; 2022. p401-432
  • Batt MM, Duffy KA, Novick AM, Metcalf CA, Epperson CN. Is Postpartum Depression Different From Depression Occurring Outside of the Perinatal Period? A Review of the Evidence. Focus (Am Psychiatr Publ). 2020 Apr;18(2):106-119. PubMed PMID: 33162848
  • Novick AM, Scott AT, Neill Epperson C, Schneck CD. Neuropsychiatric effects of tamoxifen: Challenges and opportunities. Front Neuroendocrinol. 2020 Oct;59:100869. PubMed PMID: 32822707
  • Miller CWT, Ross DA, Novick AM. "Not Dead Yet!" - Confronting the Legacy of Dualism in Modern Psychiatry. Biol Psychiatry. 2020 Apr 1;87(7):e15-e17. PubMed PMID: 32164918
  • Novick AM and Ross DA. Dualism and the 'difficult patient': why integrating neuroscience matters. British Journal of Psychiatry Advances. 2020 Nov; 26(6):327-30.
  • Novick AM, Ross DA. The Parable of Panic: Suffocation, Social Attachment, and the Critical Role of an Integrative, Biopsychosocial Formulation. Biol Psychiatry. 2019 Feb 1;85(3):e5-e6. PubMed PMID: 30621859
  • Novick AM, Levandowski ML, Laumann LE, Philip NS, Price LH, Tyrka AR. The effects of early life stress on reward processing. J Psychiatr Res. 2018 Jun;101:80-103. PubMed PMID: 29567510
  • Novick AM, Ross DA. Changing the Way We Think About (and With) Antidepressants. Biol Psychiatry. 2018 Aug 15;84(4):e27-e28. PubMed PMID: 30071948
  • Parade SH, Novick AM, Parent J, Seifer R, Klaver SJ, Marsit CJ, Gobin AP, Yang BZ, Tyrka AR. Stress exposure and psychopathology alter methylation of the serotonin receptor 2A (HTR2A) gene in preschoolers. Dev Psychopathol. 2017 Dec;29(5):1619-1626. PubMed PMID: 29162169
  • Novick AM, Mears M, Forster GL, Lei Y, Tejani-Butt SM, Watt MJ. Adolescent social defeat alters N-methyl-D-aspartic acid receptor expression and impairs fear learning in adulthood. Behav Brain Res. 2016 May 1;304:51-9. PubMed PMID: 26876136
  • Novick AM, Forster GL, Hassell JE, Davies DR, Scholl JL, Renner KJ, Watt MJ. Increased dopamine transporter function as a mechanism for dopamine hypoactivity in the adult infralimbic medial prefrontal cortex following adolescent social stress. Neuropharmacology. 2015 Oct;97:194-200. PubMed PMID: 26056032
  • Watt MJ, Roberts CL, Scholl JL, Meyer DL, Miiller LC, Barr JL, Novick AM, Renner KJ, Forster GL. Decreased prefrontal cortex dopamine activity following adolescent social defeat in male rats: role of dopamine D2 receptors. Psychopharmacology (Berl). 2014 Apr;231(8):1627-36. PubMed PMID: 24271009
  • Burke AR, Forster GL, Novick AM, Roberts CL, Watt MJ. Effects of adolescent social defeat on adult amphetamine-induced locomotion and corticoaccumbal dopamine release in male rats. Neuropharmacology. 2013 Apr;67:359-69. PubMed PMID: 23220295
  • Novick AM. Antidepressant psychopharmacology and the social brain. Psychiatry. 2011 Spring;74(1):72-86. PubMed PMID: 21463172
  • Novick AM, Forster GL, Tejani-Butt SM, Watt MJ. Adolescent social defeat alters markers of adult dopaminergic function. Brain Res Bull. 2011 Aug 10;86(1-2):123-8. PubMed PMID: 21741457
  • Novick A, Yaroslavsky I, Tejani-Butt S. Strain differences in the expression of dopamine D1 receptors in Wistar-Kyoto (WKY) and Wistar rats. Life Sci. 2008 Jul 4;83(1-2):74-8. PubMed PMID: 18558411

Professional Memberships

  • American Psychiatric Association, Member
  • Society of Biological Psychiatry, Member
  • American Society of Clinical Psychopharmacology, Member

Practice Locations

CU Medicine Psychiatry - Women's Behavioral Health and Wellness
1890 N Revere Ct
Anschutz Health Sciences Bldg, Suite 5003
Aurora, CO 80045
303-724-1646

Helen and Arthur E Johnson Depression Center - CU Anschutz Medical Campus
1890 N Revere Ct
Anschutz Health Sciences Bldg, Suite 5240
Aurora, CO 80045
303-724-3300

Hospital Affiliation
  • University of Colorado Hospital

Center Affiliations

Specialty Information

Specialties
  • Psychiatry, Board Certification (2019)
Conditions & Treatments
  • Women's Health
  • Mental Health and Behavior
Clinical Interests
My main areas of clinical focus are on 1) women's behavioral health and 2) the use of advanced pharmacological interventions, including esketamine for the treatment of Major Depressive Disorder.

Care Philosophy
I believe in providing care that: 1) Is tailored to the unique experiences and biology of the individual; 2) Is grounded in scientific evidence; 3) Promotes healthy individual development throughout the lifespan.

Public Speaking
Yes
I love helping to educate other clinicians, scientists, and the public on the topics I'm passionate about. I've giving both national and international talks on: 1) Sex steroids and the brain, and the specific influence of hormonal contraception. 2) Women's Behavioral Health, including postpartum depression, premenstrual dysphoric disorder, and the menopausal transition 2) Psychedelics and their use in psychiatric disorders 3) How dualism (splitting the mind from the brain) perpetuates stigma and impedes progress in psychiatry