Leslie Berg, PhD

Professional Titles

• Professor and Chair

Publications

• Conley JM, Berg LJ. TCR signaling: it's all about the numbers. Nat Immunol. 2019 Oct 7. [Epub ahead of print] PubMed PMID: 31591572
• Cho HS, Reboldi A, Hall JA, Berg LJ. The Tec kinase ITK is essential for ILC2 survival and epithelial integrity in the intestine. Nat Commun. 2019 Feb 15;10(1):784. PubMed PMID: 30770814
• Janeway's Immunobiology
• Cho HS, Ha S, Shin HM, Reboldi A, Hall JA, Huh JR, Usherwood EJ, Berg LJ. CD8( ) T Cells Require ITK-Mediated TCR Signaling for Migration to the Intestine. Immunohorizons. 2020 Feb 7;4(2):57-71. PubMed PMID: 32034085
• Conley JM, Gallagher MP, Rao A, Berg LJ. Activation of the Tec Kinase ITK Controls Graded IRF4 Expression in Response to Variations in TCR Signal Strength. J Immunol. 2020 Jul 15;205(2):335-345. PubMed PMID: 32493815
• Gallagher MP, Conley JM, Vangala P, Reboldi A, Garber, M, Berg LJ. The Tec kinase ITK differentially optimizes NFAT, NF-?B, and MAPK signaling during early T cell activation to regulate graded gene induction doi: https://doi.org/10.1101/2020.11.12.380725
• Riggs JR, Medina EM, Perrenoud LJ, Clambey ET, VanDyk LF, Berg LJ. Optimized detection of acute MHV68 infection with a reporter system identifies large peritoneal macrophages as a dominant target of primary infection. doi: https://doi.org/10.1101/2020.11.17.387969
• Riggs JB, Medina EM, Perrenoud LJ, Bonilla DL, Clambey ET, van Dyk LF, Berg LJ. Optimized Detection of Acute MHV68 Infection With a Reporter System Identifies Large Peritoneal Macrophages as a Dominant Target of Primary Infection. Front Microbiol. 2021;12:656979. PubMed PMID: 33767688
• Gallagher MP, Conley JM, Vangala P, Garber M, Reboldi A, Berg LJ. Hierarchy of signaling thresholds downstream of the T cell receptor and the Tec kinase ITK. Proc Natl Acad Sci U S A. 2021 Aug 31;118(35). PubMed PMID: 34452995
• Janeway's Immunobiology
• 86. Forconi, CS, DH Mulama, PS Lakshmi, J Foley, J Oteino, JD Kurtis, L Berg, JM Ong’echa, C Munz, and AM Moormann. Interplay between IL-10, IFN-?, IL-17A and PD-1 expressing EBNA1-specific CD4+ and CD8+ T cell responses in the etiologic pathway to endemic Burkitt lymphoma, Cancers, in press.
• Perrenoud, et al. Analysis of T-cell receptor induced calcium influx in primary murine T cells by full spectrum flow cytometry, Journal of Visualized Experiments, in press.
• Yee, EJ, D Gilbert, J Kaplan, L van Dyk, S Kim, L Berg, E Clambey, S Wani, MM McCarter, and CL Stewart. (2023). Evaluation of the Immune Landscape of Epstein-Barr Virus associated Gastric Cancer: Analysis from a Western, Academic Institution, manuscript submitted.
• Kolli, N, A Andreotti, A Reboldi, LJ Berg, J Kang. (2023). Expanding the Tec kinase inhibitor landscape by emergent small molecule mediated modulation of ITK, manuscript submitted.
• Berg, LJ and Pugh-Bernard, A. (2023). Investigating immunity: uncovering the mechanisms of the immune system. Futurum Careers (futurumcareers.com), May 25, 2023. https://doi.org/10.33424/FUTURUM391
• Berg, LJ. (2023). Understanding T lymphocytes’ inner workings to harness therapeutic potential. Open Access Government, in press.

Practice Locations

UCHealth University of Colorado Hospital (UCH)
12605 E. 16th Ave
Aurora, CO 80045
720-848-0000