Publications
- Russell AN, Jeffrey DA, Seedorf G, Li H, Sullivan KD, Potter H, Huang M, Dabertrand F. Intracerebral age-independent reduction of endothelium-dependent hyperpolarization and nitric oxide signalling in the Dp16 mouse model of Down syndrome. J Physiol. 2026 Jan 31. [Epub ahead of print] PubMed PMID: 41620391
- Dabertrand F. Moving targets: From channel blockers to trafficking blockers?. J Physiol. 2026 Aug;604(15):6246-6247. PubMed PMID: 42446012
- Jeffrey DA, Prince EW, Khakpour N, Ferris HR, Peters CH, Seedorf G, Romero PZ, Bueno Guerrero M, Russell AN, Glodoski K, Futia GL, Bonney SK, Thornton MA, Gibson EA, Proenza C, Garcia AM, Tsoukias NM, Dabertrand F. Pericyte K(ATP) channel hyperactivity redistributes cortical blood flow in a CADASIL mouse model. Nat Cardiovasc Res. 2026 Aug;5(8):725-743. PubMed PMID: 42547848
- Iruela-Arispe ML, Hinman JD, Yang AC, Dabertrand F, Lee JM, Howell GR. A collaborative framework for uncovering molecular and cellular drivers of VCID: Foundations for future interventions in dementia. Alzheimers Dement. 2026 Aug;22(8):e71701. PubMed PMID: 42581297
- Dabertrand F. When electricity isn't enough: ORAI channels reinforce neurovascular coupling. Sci Signal. 2026 Sep;19(953):eaek0208. PubMed PMID: 42679015
- Ouellette J, Warsi S, Romero P, Khare P, Naz S, Aubert-Tandon L, Freitas-Andrade M, Pileggi C, Yandiev S, Raman-Nair J, Yee J, Blakeley N, Govindaswamy B, Comin CH, Harper ME, Soundara Manickam D, Dabertrand F, Saghatelyan A, Lacoste B. Purinergic receptor activation rectifies autism-associated endothelial dysfunction. Neuron. 2026 Sep 30. [Epub ahead of print] PubMed PMID: 42815469
- Khakpour N, Sancho M, Klug NR, Ferris HR, Dabertrand F, Nelson MT, Tsoukias NM. Electromechanical Dynamics and Myogenic Responses in Cerebral Smooth Muscle Cells and Capillary Pericytes. J. Physiol. 2026 In press
- Lee MD, Osborne C, Stevenson R, MacDonald A, Ebner G, Jeffrey DA, MacDonald MA, Zhang X, Buckley C, Dabertrand F, Machin DR, Au J, Harraz OF, Tykocki N, McCarron JG, Wilson C. VasoTracker 2: Open-source software and hardware for tracking blood vessel diameter and assessing vascular function. J Physiol. 2025 Oct 19. [Epub ahead of print] PubMed PMID: 41110981
- Osmond MJ, Dabertrand F, Quillinan N, Su EJ, Lawrence DA, Marr DWM, Neeves KB. Micrometer-scale tPA beads amplify plasmin generation for enhanced thrombolytic therapy. Bioeng Transl Med. 2025 Jul;10(4):e70012. PubMed PMID: 40708974
- Jeffrey DA, Russell AN, Ferris HR, Romero PZ, Bueno Guerrero M, Fontaine JT, Hashad AM, Bolt MA, Fosdick BK, Rosehart AC, Harraz OF, Dabertrand F. Estrogen Enhances SK Channel Activity to Limit Hippocampal Arteriole Constriction. Circ Res. 2025 Aug;137(4):456-470. PubMed PMID: 40567232
- Ferris HR, Jeffrey DA, Guerrero MB, Birnbaumer L, Zheng F, Dabertrand F. Increased luminal pressure in brain capillaries drives TRPC3-dependent depolarization and constriction of transitional pericytes. Sci Signal. 2025 Apr 29;18(884):eads1903. PubMed PMID: 40299956
- Schaid TR Jr, Mitra S, Stafford P, DeBot M, Thielen O, Hallas W, Cralley A, Gallagher L, Jeffrey D, Hansen KC, D'Alessandro A, Silliman CC, Dabertrand F, Cohen MJ. Endothelial Cell Calcium Influx Mediates Trauma-induced Endothelial Permeability. Ann Surg. 2025 Apr 1;281(4):671-681. PubMed PMID: 38073572
- Dabertrand F. Sweet relief: make the brain Glo against diabetic cognitive fog. J Physiol. 2024 Oct 15. [Epub ahead of print] PubMed PMID: 39405447
- Profaci CP, Harvey SS, Bajc K, Zhang TZ, Jeffrey DA, Zhang AZ, Nemec KM, Davtyan H, O'Brien CA, McKinsey GL, Longworth A, McMullen TP, Capocchi JK, Gonzalez JG, Lawson DA, Arnold TD, Davalos D, Blurton-Jones M, Dabertrand F, Bennett FC, Daneman R. Microglia are not necessary for maintenance of blood-brain barrier properties in health, but PLX5622 alters brain endothelial cholesterol metabolism. Neuron. 2024 Sep 4;112(17):2910-2921.e7. PubMed PMID: 39142282
- Activity-dependent regulation of vascular cholesterol metabolism acts as a negative feedback mechanism for neurovascular coupling CP Profaci, KL Foreman, L Spieth, V Coelho-Santos, SA Berghoff, JT Fontaine, DA Jeffrey, SP Palecek, EV Shusta, G Saher, AY Shih, F Dabertrand, R Daneman
- Jeffrey DA, Russell A, Guerrero MB, Fontaine JT, Romero P, Rosehart AC, Dabertrand F. Estrogen regulates myogenic tone in hippocampal arterioles by enhanced basal release of nitric oxide and endothelial SK (Ca) channel activity. bioRxiv. 2023 Aug 17. PubMed PMID: 37645715
- Jeffrey DA, Fontaine JT, Dabertrand F. Ex vivo capillary-parenchymal arteriole approach to study brain pericyte physiology. Neurophotonics. 2022 Jul;9(3):031919. PubMed PMID: 36278784
- Carnevale D, Dabertrand F, Lecrux C, Morel JL. Editorial: Involvement of Blood Brain Barrier Efficacy, Neurovascular Coupling, and Angiogenesis in the Healthy and Diseased Brain, Volume II. Front Physiol. 2022;13:829901. PubMed PMID: 35173632
- Rosehart AC, Longden TA, Weir N, Fontaine JT, Joutel A, Dabertrand F. Prostaglandin E(2) Dilates Intracerebral Arterioles When Applied to Capillaries: Implications for Small Vessel Diseases. Front Aging Neurosci. 2021;13:695965. PubMed PMID: 34483880
- Koide M, Harraz OF, Dabertrand F, Longden TA, Ferris HR, Wellman GC, Hill-Eubanks DC, Greenstein AS, Nelson MT. Differential restoration of functional hyperemia by antihypertensive drug classes in hypertension-related cerebral small vessel disease. J Clin Invest. 2021 Sep 15;131(18). PubMed PMID: 34351870
- Dabertrand F, Harraz OF, Koide M, Longden TA, Rosehart AC, Hill-Eubanks DC, Joutel A, Nelson MT. PIP(2) corrects cerebral blood flow deficits in small vessel disease by rescuing capillary Kir2.1 activity. Proc Natl Acad Sci U S A. 2021 Apr 27;118(17). PubMed PMID: 33875602
- Rosehart AC, Johnson AC, Dabertrand F (2019). Ex vivo pressurized hippocampal capillary-parenchymal arteriole preparation for functional study. J Vis Exp In press.