C. Neill Epperson, MD
Professor, Psychiatry-Admin

Publications

• Metcalf CA, Johnson RL, Duffy KA, Freeman EW, Sammel MD, Epperson CN. Depressed, stressed, and inflamed: C-reactive protein linked with depression symptoms in midlife women with both childhood and current life stress. Stress Health. 2023 Sep 7. [Epub ahead of print] PubMed PMID: 37679965
• Olsavsky AK, Chirico I, Ali D, Christensen H, Boggs B, Svete L, Ketcham K, Hutchison K, Zeanah C, Tottenham N, Riggs P, Epperson CN. Maternal Childhood Maltreatment, Internal Working Models, and Perinatal Substance Use: Is There a Role for Hyperkatifeia? A Systematic Review. Subst Abuse. 2023;17:11782218231186371. PubMed PMID: 37476500
• Olsavsky AK, Epperson CN. Recalculating the Risk of Prenatal Magnetic Resonance Imaging Research: Previously Unidentified Potential Harms Associated With Urine Pregnancy Testing. Biol Psychiatry Cogn Neurosci Neuroimaging. 2023 Jun;8(6):585-587. PubMed PMID: 37286289
• Giano Z, Schwab-Reese L, Mishra AA, Hubach RD, Johnson RL, Epperson CN, Sammel MD. Intersectionality and Adverse Childhood Experiences: Comparing Subgroups of Sex, Race/Ethnicity, and Sexual Orientation. Am J Prev Med. 2023 Jul;65(1):30-38. PubMed PMID: 36870786
• Page CE, Soreth B, Metcalf CA, Johnson RL, Duffy KA, Sammel MD, Loughead J, Epperson CN. Natural vs. surgical postmenopause and psychological symptoms confound the effect of menopause on executive functioning domains of cognitive experience. Maturitas. 2023 Apr;170:64-73. PubMed PMID: 36806931
• Epperson CN, Rubinow DR, Meltzer-Brody S, Deligiannidis KM, Riesenberg R, Krystal AD, Bankole K, Huang MY, Li H, Brown C, Kanes SJ, Lasser R. Effect of brexanolone on depressive symptoms, anxiety, and insomnia in women with postpartum depression: Pooled analyses from 3 double-blind, randomized, placebo-controlled clinical trials in the HUMMINGBIRD clinical program. J Affect Disord. 2023 Jan 1;320:353-359. PubMed PMID: 36191643
• Hantsoo L, Duffy KA, Sammel M, Johnson RL, Kim D, Grillon C, Epperson CN. Enduring impact of childhood adversity: Affective modulation of acoustic startle response during pregnancy and postpartum. Physiol Behav. 2023 Jan 1;258:114031. PubMed PMID: 36402424
• Novick AM, Stoddard J, Johnson RL, Duffy KA, Berkowitz L, Costa VD, Sammel MD, Epperson CN. Adverse childhood experiences and hormonal contraception: Interactive impact on sexual reward function. PLoS One. 2023;18(1):e0279764. PubMed PMID: 36649369
• Duffy KA, Sammel MD, Johnson RL, Kim DR, Wang EY, Ewing G, Hantsoo L, Kornfield SL, Bale TL, Epperson CN. Maternal adverse childhood experiences impact fetal adrenal volume in a sex-specific manner. Biol Sex Differ. 2023 Feb 17;14(1):7. PubMed PMID: 36803442
• Novick AM, Stoddard J, Johnson RL, Duffy KA, Berkowitz L, Costa VD, Sammel MD, Epperson CN. Adverse childhood experiences and hormonal contraception: Interactive impact on sexual reward function. PLoS One. 2023;18(1):e0279764. PubMed PMID: 36649369
• Hantsoo L, Duffy KA, Sammel M, Johnson RL, Kim D, Grillon C, Epperson CN. Enduring impact of childhood adversity: Affective modulation of acoustic startle response during pregnancy and postpartum. Physiol Behav. 2023 Jan 1;258:114031. PubMed PMID: 36402424
• Epperson CN, Rubinow DR, Meltzer-Brody S, Deligiannidis KM, Riesenberg R, Krystal AD, Bankole K, Huang MY, Li H, Brown C, Kanes SJ, Lasser R. Effect of brexanolone on depressive symptoms, anxiety, and insomnia in women with postpartum depression: Pooled analyses from 3 double-blind, randomized, placebo-controlled clinical trials in the HUMMINGBIRD clinical program. J Affect Disord. 2023 Jan 1;320:353-359. PubMed PMID: 36191643
• Novick AM, Duffy KA, Johnson RL, Sammel MD, Cao W, Strasser AA, Sofuoglu M, Kuzma A, Loughead J, Morrow AL, Epperson CN. Effect of progesterone administration in male and female smokers on nicotine withdrawal and neural response to smoking cues: role of progesterone conversion to allopregnanolone. Biol Sex Differ. 2022 Oct 23;13(1):60. PubMed PMID: 36274158
• Kornfield SL, Johnson RL, Hantsoo LV, Kaminsky RB, Waller R, Sammel M, Epperson CN. Engagement in and Benefits of a Short-Term, Brief Psychotherapy Intervention for PTSD During Pregnancy. Front Psychiatry. 2022;13:882429. PubMed PMID: 35782453
• Novick AM, Duffy KA, Johnson RL, Sammel MD, Cao W, Strasser AA, Sofuoglu M, Kuzma A, Loughead J, Epperson CN. Progesterone Increases Nicotine Withdrawal and Anxiety in Male but Not Female Smokers During Brief Abstinence. Nicotine Tob Res. 2022 Nov 12;24(12):1898-1905. PubMed PMID: 35713950
• Santoro NF, Coons HL, El Khoudary SR, Epperson CN, Holt-Lunstad J, Joffe H, Lindsey SH, Marlatt KL, Montella P, Richard-Davis G, Rockette-Wagner B, Salive ME, Stuenkel C, Thurston RC, Woods N, Wyatt H. NAMS 2021 Utian Translational Science SymposiumSeptember 2021, Washington, DCCharting the path to health in midlife and beyond: the biology and practice of wellness. Menopause. 2022 May 1;29(5):504-513. PubMed PMID: 35486944
• Dubol M, Wikström J, Lanzenberger R, Epperson CN, Sundström-Poromaa I, Comasco E. Grey matter correlates of affective and somatic symptoms of premenstrual dysphoric disorder. Sci Rep. 2022 Apr 9;12(1):5996. PubMed PMID: 35397641
• Wyman JF, Cain CH, Epperson CN, Fitzgerald CM, Gahagan S, Newman DK, Rudser K, Smith AL, Vaughan CP, Sutcliffe S. Urination Frequency Ranges in Healthy Women. Nurs Res. 2022 Sep-Oct 01;71(5):341-352. PubMed PMID: 35319538
• Gu X, Dubol M, Stiernman L, Wikström J, Hahn A, Lanzenberger R, Epperson CN, Bixo M, Sundström-Poromaa I, Comasco E. White matter microstructure and volume correlates of premenstrual dysphoric disorder. J Psychiatry Neurosci. 2022 Jan-Feb;47(1):E67-E76. PubMed PMID: 35197364
• Wikman A, Sacher J, Bixo M, Hirschberg AL, Kopp Kallner H, Epperson CN, Comasco E, Sundström Poromaa I. Prevalence and correlates of current suicidal ideation in women with premenstrual dysphoric disorder. BMC Womens Health. 2022 Feb 11;22(1):35. PubMed PMID: 35148753
• Novick AM, Johnson RL, Lazorwitz A, Belyavskaya A, Berkowitz L, Norton A, Sammel MD, Epperson CN. Discontinuation of hormonal contraception due to changes in mood and decreases in sexual desire: the role of adverse childhood experiences. Eur J Contracept Reprod Health Care. 2022 Jun;27(3):212-220. PubMed PMID: 35133231
• Metcalf CA, Johnson RL, Novick AM, Freeman EW, Sammel MD, Anthony LG, Epperson CN. Adverse childhood experiences interact with inflammation and menopause transition stage to predict verbal memory in women. Brain Behav Immun Health. 2022 Mar;20:100411. PubMed PMID: 35079709
• Duffy KA, Epperson CN. Evaluating the evidence for sex differences: a scoping review of human neuroimaging in psychopharmacology research. Neuropsychopharmacology. 2022 Jan;47(2):430-443. PubMed PMID: 34732844
• Brady SS, Bavendam TG, Bradway CK, Conroy B, Dowling-Castronovo A, Epperson CN, Hijaz AK, Hsi RS, Huss K, Kim M, Lazar J, Lee RK, Liu CK, Loizou CN, Miran S, Mody L, Norton JM, Reynolds WS, Sutcliffe S, Zhang N, Hokanson JA. Noncancerous Genitourinary Conditions as a Public Health Priority: Conceptualizing the Hidden Burden. Urology. 2022 Aug;166:39-49. PubMed PMID: 34536410
• Comasco E, Kopp Kallner H, Bixo M, Hirschberg AL, Nyback S, de Grauw H, Epperson CN, Sundström-Poromaa I. Ulipristal Acetate for Treatment of Premenstrual Dysphoric Disorder: A Proof-of-Concept Randomized Controlled Trial. Am J Psychiatry. 2020 Dec 10;:appiajp202020030286. [Epub ahead of print] PubMed PMID: 33297719
• Batt MM, Duffy KA, Novick AM, Metcalf CA, Epperson CN. Is Postpartum Depression Different From Depression Occurring Outside of the Perinatal Period? A Review of the Evidence. Focus (Am Psychiatr Publ). 2020 Apr;18(2):106-119. PubMed PMID: 33162848
• Morgan CP, Shetty AC, Chan JC, Berger DS, Ament SA, Epperson CN, Bale TL. Repeated sampling facilitates within- and between-subject modeling of the human sperm transcriptome to identify dynamic and stress-responsive sncRNAs. Sci Rep. 2020 Oct 15;10(1):17498. PubMed PMID: 33060642
• Sutcliffe S, Cain C, Bavendam T, Epperson CN, Fitzgerald CM, Gahagan S, Markland AD, Shoham DA, Smith AL, Rudser K. Revisiting the Spectrum of Bladder Health: Relationships Between Lower Urinary Tract Symptoms and Multiple Measures of Well-Being. J Womens Health (Larchmt). 2020 Aug;29(8):1077-1090. PubMed PMID: 32831001
• Mauvais-Jarvis F, Bairey Merz N, Barnes PJ, Brinton RD, Carrero JJ, DeMeo DL, De Vries GJ, Epperson CN, Govindan R, Klein SL, Lonardo A, Maki PM, McCullough LD, Regitz-Zagrosek V, Regensteiner JG, Rubin JB, Sandberg K, Suzuki A. Sex and gender: modifiers of health, disease, and medicine. Lancet. 2020 Aug 22;396(10250):565-582. PubMed PMID: 32828189
• Epperson CN, Huang MY, Cook K, Gupta D, Chawla A, Greenberg PE, Eldar-Lissai A. Healthcare resource utilization and costs associated with postpartum depression among commercially insured households. Curr Med Res Opin. 2020 Oct;36(10):1707-1716. PubMed PMID: 32696705
• Kang-Yi CD, Chao B, Teng S, Locke J, Mandell DS, Wong YI, Epperson CN. Psychiatric Diagnoses and Treatment Preceding Schizophrenia in Adolescents Aged 9-17 Years. Front Psychiatry. 2020;11:487. PubMed PMID: 32581869
• Shanmugan S, Cao W, Satterthwaite TD, Sammel MD, Ashourvan A, Bassett DS, Ruparel K, Gur RC, Epperson CN, Loughead J. Impact of childhood adversity on network reconfiguration dynamics during working memory in hypogonadal women. Psychoneuroendocrinology. 2020 Sep;119:104710. PubMed PMID: 32563173
• Hantsoo L, Epperson CN. Allopregnanolone in premenstrual dysphoric disorder (PMDD): Evidence for dysregulated sensitivity to GABA-A receptor modulating neuroactive steroids across the menstrual cycle. Neurobiol Stress. 2020 May;12:100213. PubMed PMID: 32435664
• Epperson CN, Duffy KA, Johnson RL, Sammel MD, Newman DK. Enduring impact of childhood adversity on lower urinary tract symptoms in adult women. Neurourol Urodyn. 2020 Jun;39(5):1472-1481. PubMed PMID: 32368829
• Dubol M, Epperson CN, Lanzenberger R, Sundström-Poromaa I, Comasco E. Neuroimaging premenstrual dysphoric disorder: A systematic and critical review. Front Neuroendocrinol. 2020 Apr;57:100838. PubMed PMID: 32268180
• Duffy KA, Ziolek TA, Epperson CN. Filling the Regulatory Gap: Potential Role of Institutional Review Boards in Promoting Consideration of Sex as a Biological Variable. J Womens Health (Larchmt). 2020 Jun;29(6):868-875. PubMed PMID: 32267784
• Shanmugan S, Sammel MD, Loughead J, Ruparel K, Gur RC, Brown TE, Faust J, Domchek S, Epperson CN. Executive function after risk-reducing salpingo-oophorectomy in BRCA1 and BRCA2 mutation carriers: does current mood and early life adversity matter?. Menopause. 2020 Jul;27(7):746-755. PubMed PMID: 32187134
• Mamtani R, Wang XV, Gyawali B, DiPaola RS, Epperson CN, Haas NB, Dutcher JP. Association between age and sex and mortality after adjuvant therapy for renal cancer. Cancer. 2019 Jan 8. [Epub ahead of print] PubMed PMID: 30620389
• Epperson CN, Bale TL. Deciphering the Brain Before Birth. Biol Psychiatry. 2019 Jan 15;85(2):90. PubMed PMID: 30573050
• Hantsoo L, Jašarevic E, Criniti S, McGeehan B, Tanes C, Sammel MD, Elovitz MA, Compher C, Wu G, Epperson CN. Childhood adversity impact on gut microbiota and inflammatory response to stress during pregnancy. Brain Behav Immun. 2019 Jan;75:240-250. PubMed PMID: 30399404
• Chung YS, Poppe A, Novotny S, Epperson CN, Kober H, Granger DA, Blumberg HP, Ochsner K, Gross JJ, Pearlson G, Stevens MC. A preliminary study of association between adolescent estradiol level and dorsolateral prefrontal cortex activity during emotion regulation. Psychoneuroendocrinology. 2019 Nov;109:104398. PubMed PMID: 31394491
• Hodes GE, Epperson CN. Sex Differences in Vulnerability and Resilience to Stress Across the Life Span. Biol Psychiatry. 2019 Sep 15;86(6):421-432. PubMed PMID: 31221426
• Sutcliffe S, Bavendam T, Cain C, Epperson CN, Fitzgerald CM, Gahagan S, Markland AD, Shoham DA, Smith AL, Townsend MK, Rudser K. The Spectrum of Bladder Health: The Relationship Between Lower Urinary Tract Symptoms and Interference with Activities. J Womens Health (Larchmt). 2019 Jun;28(6):827-841. PubMed PMID: 31058573
• Hantsoo L, Kornfield S, Anguera MC, Epperson CN. Inflammation: A Proposed Intermediary Between Maternal Stress and Offspring Neuropsychiatric Risk. Biol Psychiatry. 2019 Jan 15;85(2):97-106. PubMed PMID: 30314641
• Hantsoo L, Kornfield S, Iannelli C, Podcasy J, Metzger D, Sammel MD, Epperson CN. Glucocorticoid-immune response to acute stress in women and men living with HIV. J Behav Med. 2019 Dec;42(6):1153-1158. PubMed PMID: 30888591
• Mamtani R, Wang XV, Gyawali B, DiPaola RS, Epperson CN, Haas NB, Dutcher JP. Association between age and sex and mortality after adjuvant therapy for renal cancer. Cancer. 2019 May 15;125(10):1637-1644. PubMed PMID: 30620389
• Epperson CN, Bale TL. Deciphering the Brain Before Birth. Biol Psychiatry. 2019 Jan 15;85(2):90. PubMed PMID: 30573050
• Hantsoo L, Jašarevic E, Criniti S, McGeehan B, Tanes C, Sammel MD, Elovitz MA, Compher C, Wu G, Epperson CN. Childhood adversity impact on gut microbiota and inflammatory response to stress during pregnancy. Brain Behav Immun. 2019 Jan;75:240-250. PubMed PMID: 30399404
• Hantsoo L, Kornfield S, Anguera MC, Epperson CN. Inflammation: A Proposed Intermediary Between Maternal Stress and Offspring Neuropsychiatric Risk. Biol Psychiatry. 2019 Jan 15;85(2):97-106. PubMed PMID: 30314641
• Kim DR, Wang E, McGeehan B, Snell J, Ewing G, Iannelli C, O'Reardon JP, Sammel MD, Epperson CN. Randomized controlled trial of transcranial magnetic stimulation in pregnant women with major depressive disorder. Brain Stimul. 2019 Jan - Feb;12(1):96-102. PubMed PMID: 30249416
• Kim DR, Wang E, McGeehan B, Snell J, Ewing G, Iannelli C, O'Reardon JP, Sammel MD, Epperson CN. Randomized controlled trial of transcranial magnetic stimulation in pregnant women with major depressive disorder. Brain Stimul. 2019 Jan - Feb;12(1):96-102. PubMed PMID: 30249416
• Nguyen HB, Loughead J, Lipner E, Hantsoo L, Kornfield SL, Epperson CN. What has sex got to do with it? The role of hormones in the transgender brain. Neuropsychopharmacology. 2019 Jan;44(1):22-37. PubMed PMID: 30082887
• Nguyen HB, Loughead J, Lipner E, Hantsoo L, Kornfield SL, Epperson CN. What has sex got to do with it? The role of hormones in the transgender brain. Neuropsychopharmacology. 2019 Jan;44(1):22-37. PubMed PMID: 30082887
• Bromberger JT, Epperson CN. Depression During and After the Perimenopause: Impact of Hormones, Genetics, and Environmental Determinants of Disease. Obstet Gynecol Clin North Am. 2018 Dec;45(4):663-678. PubMed PMID: 30401549
• Nguyen HB, Chavez AM, Lipner E, Hantsoo L, Kornfield SL, Davies RD, Epperson CN. Gender-Affirming Hormone Use in Transgender Individuals: Impact on Behavioral Health and Cognition. Curr Psychiatry Rep. 2018 Oct 11;20(12):110. PubMed PMID: 30306351
• Markland A, Chu H, Epperson CN, Nodora J, Shoham D, Smith A, Sutcliffe S, Townsend M, Zhou J, Bavendam T. Occupation and lower urinary tract symptoms in women: A rapid review and meta-analysis from the PLUS research consortium. Neurourol Urodyn. 2018 Nov;37(8):2881-2892. PubMed PMID: 30272814
• Meltzer-Brody S, Colquhoun H, Riesenberg R, Epperson CN, Deligiannidis KM, Rubinow DR, Li H, Sankoh AJ, Clemson C, Schacterle A, Jonas J, Kanes S. Brexanolone injection in post-partum depression: two multicentre, double-blind, randomised, placebo-controlled, phase 3 trials. Lancet. 2018 Sep 22;392(10152):1058-1070. PubMed PMID: 30177236
• Nugent BM, O'Donnell CM, Epperson CN, Bale TL. Placental H3K27me3 establishes female resilience to prenatal insults. Nat Commun. 2018 Jul 2;9(1):2555. PubMed PMID: 29967448
• Cooney LG, Milman LW, Hantsoo L, Kornfield S, Sammel MD, Allison KC, Epperson CN, Dokras A. Cognitive-behavioral therapy improves weight loss and quality of life in women with polycystic ovary syndrome: a pilot randomized clinical trial. Fertil Steril. 2018 Jul 1;110(1):161-171.e1. PubMed PMID: 29908771
• Nanga RPR, DeBrosse C, Kumar D, Roalf D, McGeehan B, D'Aquilla K, Borthakur A, Hariharan H, Reddy D, Elliott M, Detre JA, Epperson CN, Reddy R. Reproducibility of 2D GluCEST in healthy human volunteers at 7 T. Magn Reson Med. 2018 Nov;80(5):2033-2039. PubMed PMID: 29802635
• Hantsoo L, Golden CEM, Kornfield S, Grillon C, Epperson CN. Startling Differences: Using the Acoustic Startle Response to Study Sex Differences and Neurosteroids in Affective Disorders. Curr Psychiatry Rep. 2018 May 18;20(6):40. PubMed PMID: 29777410
• Kornfield SL, Hantsoo L, Epperson CN. What Does Sex Have to Do with It? The Role of Sex as a Biological Variable in the Development of Posttraumatic Stress Disorder. Curr Psychiatry Rep. 2018 May 18;20(6):39. PubMed PMID: 29777319
• Kornfield SL, Kang-Yi CD, Mandell DS, Epperson CN. Predictors and Patterns of Psychiatric Treatment Dropout During Pregnancy Among Low-Income Women. Matern Child Health J. 2018 Feb;22(2):226-236. PubMed PMID: 29143169
• Kang-Yi CD, Kornfield SL, Epperson CN, Mandell DS. Relationship Between Pregnancy Complications and Psychiatric Disorders: A Population-Based Study With a Matched Control Group. Psychiatr Serv. 2018 Mar 1;69(3):300-307. PubMed PMID: 29137553
• Hantsoo L, Criniti S, Khan A, Moseley M, Kincler N, Faherty LJ, Epperson CN, Bennett IM. A Mobile Application for Monitoring and Management of Depressed Mood in a Vulnerable Pregnant Population. Psychiatr Serv. 2018 Jan 1;69(1):104-107. PubMed PMID: 29032705
• Flynn HA, Spino C, Guille C, Deligiannidis KM, Maki P, Jahnke J, Rosenblum KL, Epperson CN, Weiss SJ. A Collaborative, Network-Based Approach to Advance Women's Depression Research in the United States: Preliminary Findings. J Womens Health (Larchmt). 2018 Jan;27(1):51-57. PubMed PMID: 28727948