Jenna Demedis, MD

Assistant Professor, Pediatrics-Heme/Onc and Bone Marrow Transplantation


FacultyPhoto
Medical School
  • MD, Vanderbilt University School of Medicine (2012)
Graduate School
  • MSCS, University of Colorado Denver (2018)
Undergraduate School
  • BS, University of California–Los Angeles (CA) (2008)
Residency
  • University of Colorado (Children's Hospital Colorado) Program, Pediatrics (2015)
Fellowships
  • University of Colorado (Children's Hospital Colorado) Program, Pediatric Hematology / Oncology (2018)
Department
Pediatrics-Heme/Onc and Bone Marrow Transplantation

Professional Titles

  • Assistant Professor of Pediatrics

Research Interests

My research interests are in pediatric oncology outcomes, late effects, and patient quality of life.

Publications

  • Faulk KE, Sopfe JM, Campbell K, Liptzin DR, Liu AK, Franklin ARK, Cost CR. Pulmonary toxicity in paediatric patients with relapsed or refractory Hodgkin lymphoma receiving brentuximab vedotin. Br J Haematol. 2018 Sep 10. [Epub ahead of print] PubMed PMID: 30198571
  • Zastoupil L, McIntosh A, Sopfe J, Burrows J, Kraynik J, Lane L, Hanson J, Seltz LB. Positive Impact of Transition From Noon Conference to Academic Half Day in a Pediatric Residency Program. Acad Pediatr. 2017 May - Jun;17(4):436-442. PubMed PMID: 28130128
  • Esbenshade AJ, Sopfe J, Zhao Z, Li Z, Campbell K, Simmons JH, Friedman DL. Screening for vitamin D insufficiency in pediatric cancer survivors. Pediatr Blood Cancer. 2014 Apr;61(4):723-8. PubMed PMID: 24194420
  • Sopfe J, Simmons JH. Failure to thrive, hyponatremia, and hyperkalemia in a neonate. Pediatr Ann. 2013 May;42(5):74-9. PubMed PMID: 23641881
  • Smith HA, Boyd J, Fuchs DC, Melvin K, Berry P, Shintani A, Eden SK, Terrell MK, Boswell T, Wolfram K, Sopfe J, Barr FE, Pandharipande PP, Ely EW. Diagnosing delirium in critically ill children: Validity and reliability of the Pediatric Confusion Assessment Method for the Intensive Care Unit. Crit Care Med. 2011 Jan;39(1):150-7. PubMed PMID: 20959783
  • Grimes A, Mohamed A, Sopfe J, Hill R, Lynch J. Hyperglycemia During Childhood Cancer Therapy: Incidence, Implications, and Impact on Outcomes. J Natl Cancer Inst Monogr. 2019 Sep 1;2019(54):132-138. PubMed PMID: 31532529
  • Phillips CA, Razzaghi H, Aglio T, McNeil MJ, Salvesen-Quinn M, Sopfe J, Wilkes JJ, Forrest CB, Bailey LC. Development and evaluation of a computable phenotype to identify pediatric patients with leukemia and lymphoma treated with chemotherapy using electronic health record data. Pediatr Blood Cancer. 2019 Sep;66(9):e27876. PubMed PMID: 31207054
  • Sopfe J, Pyle L, Keating AK, Campbell K, Liu AK, Wadwa RP, Verneris MR, Giller RH, Forlenza GP. Malglycemia is associated with poor outcomes in pediatric and adolescent hematopoietic stem cell transplant patients. Blood Adv. 2019 Feb 12;3(3):350-359. PubMed PMID: 30718242
  • Sopfe J, Endres A, Campbell K, Hayes K, Trout AT, Liang X, Lorsbach R, O'Brien MM, Cost CR. Castleman disease in pediatrics: Insights on presentation, treatment, and outcomes from a two-site retrospective cohort study. Pediatr Blood Cancer. 2019 May;66(5):e27613. PubMed PMID: 30680887
  • Macaruso N, Campbell K, Cost C, Sopfe J. Provider Documentation of Tinnitus in Childhood Cancer Survivors. J Pediatr Hematol Oncol. 2020 Oct 15. [Epub ahead of print] PubMed PMID: 33065711
  • Sopfe J, Greffe B, Treece AL. Metastatic NUT Midline Carcinoma Treated With Aggressive Neoadjuvant Chemotherapy, Radiation, and Resection: A Case Report and Review of the Literature. J Pediatr Hematol Oncol. 2020 Jun 16. [Epub ahead of print] PubMed PMID: 32555032
  • Sopfe J, Gupta A, Appiah LC, Chow EJ, Peterson PN. Sexual Dysfunction in Adolescent and Young Adult Survivors of Childhood Cancer: Presentation, Risk Factors, and Evaluation of an Underdiagnosed Late Effect: A Narrative Review. J Adolesc Young Adult Oncol. 2020 Oct;9(5):549-560. PubMed PMID: 32380878
  • Sopfe J, Vigers T, Pyle L, Giller RH, Forlenza GP. Safety and Accuracy of Factory-Calibrated Continuous Glucose Monitoring in Pediatric Patients Undergoing Hematopoietic Stem Cell Transplantation. Diabetes Technol Ther. 2020 Oct;22(10):727-733. PubMed PMID: 32105513
  • Grimes A, Mohamed A, Sopfe J, Hill R, Lynch J. Hyperglycemia During Childhood Cancer Therapy: Incidence, Implications, and Impact on Outcomes. J Natl Cancer Inst Monogr. 2019 Sep 1;2019(54):132-138. PubMed PMID: 31532529
  • Phillips CA, Razzaghi H, Aglio T, McNeil MJ, Salvesen-Quinn M, Sopfe J, Wilkes JJ, Forrest CB, Bailey LC. Development and evaluation of a computable phenotype to identify pediatric patients with leukemia and lymphoma treated with chemotherapy using electronic health record data. Pediatr Blood Cancer. 2019 Sep;66(9):e27876. PubMed PMID: 31207054
  • Sopfe J, Marsh R, Frederick NN, Klosky JL, Chow EJ, Dorsey Holliman B, Peterson PN. Adolescent and young adult childhood cancer survivors' preferences for screening and education of sexual function. Pediatr Blood Cancer. 2021 Jul 10;:e29229. [Epub ahead of print] PubMed PMID: 34245209
  • Sopfe J, Pettigrew J, Afghahi A, Appiah LC, Coons HL. Interventions to Improve Sexual Health in Women Living with and Surviving Cancer: Review and Recommendations. Cancers (Basel). 2021 Jun 24;13(13). PubMed PMID: 34202477
  • Bodlak A, Chang K, Channel J, Treece AL, Donaldson N, Cost CR, Garrington TP, Greffe B, Luna-Fineman S, Sopfe J, Loeb DM, Hayashi M. Circulating Plasma Tumor DNA Is Superior to Plasma Tumor RNA Detection in Ewing Sarcoma Patients: ptDNA and ptRNA in Ewing Sarcoma. J Mol Diagn. 2021 Jul;23(7):872-881. PubMed PMID: 33887462
  • Sopfe J, Campbell K, Keating AK, Pyle L, Liu AK, Verneris MR, Giller RH, Forlenza GP. Glycemic variability is associated with poor outcomes in pediatric hematopoietic stem cell transplant patients. Pediatr Blood Cancer. 2020 Nov;67(11):e28626. PubMed PMID: 33480469
  • Sopfe J, Marsh R, Ziniel SI, Klosky JL, Chow EJ, Dorsey Holliman B, Peterson PN. Evaluation of the v2.0 Brief Profiles for Sexual Function and Satisfaction PROMIS in Adolescent and Young Adult Childhood Cancer Survivors. J Adolesc Young Adult Oncol. 2021 Aug;10(4):418-424. PubMed PMID: 33136468
  • Macaruso N, Campbell K, Cost C, Sopfe J. Provider Documentation of Tinnitus in Childhood Cancer Survivors. J Pediatr Hematol Oncol. 2021 Jul 1;43(5):e642-e647. PubMed PMID: 33065711
  • Sopfe J, Greffe B, Treece AL. Metastatic NUT Midline Carcinoma Treated With Aggressive Neoadjuvant Chemotherapy, Radiation, and Resection: A Case Report and Review of the Literature. J Pediatr Hematol Oncol. 2021 Jan;43(1):e73-e75. PubMed PMID: 32555032
  • Sopfe J, Gupta A, Appiah LC, Chow EJ, Peterson PN. Sexual Dysfunction in Adolescent and Young Adult Survivors of Childhood Cancer: Presentation, Risk Factors, and Evaluation of an Underdiagnosed Late Effect: A Narrative Review. J Adolesc Young Adult Oncol. 2020 Oct;9(5):549-560. PubMed PMID: 32380878
  • Sopfe J, Vigers T, Pyle L, Giller RH, Forlenza GP. Safety and Accuracy of Factory-Calibrated Continuous Glucose Monitoring in Pediatric Patients Undergoing Hematopoietic Stem Cell Transplantation. Diabetes Technol Ther. 2020 Oct;22(10):727-733. PubMed PMID: 32105513
  • Reinman L, Coons HL, Sopfe J, Casey R. Psychosexual Care of Adolescent and Young Adult (AYA) Cancer Survivors. Children (Basel). 2021 Nov 16;8(11). PubMed PMID: 34828771
  • Sopfe J, Marsh R, Frederick NN, Klosky JL, Chow EJ, Dorsey Holliman B, Peterson PN. Adolescent and young adult childhood cancer survivors' preferences for screening and education of sexual function. Pediatr Blood Cancer. 2021 Dec;68(12):e29229. PubMed PMID: 34245209
  • Sopfe J, Pettigrew J, Afghahi A, Appiah LC, Coons HL. Interventions to Improve Sexual Health in Women Living with and Surviving Cancer: Review and Recommendations. Cancers (Basel). 2021 Jun 24;13(13). PubMed PMID: 34202477
  • Bodlak A, Chang K, Channel J, Treece AL, Donaldson N, Cost CR, Garrington TP, Greffe B, Luna-Fineman S, Sopfe J, Loeb DM, Hayashi M. Circulating Plasma Tumor DNA Is Superior to Plasma Tumor RNA Detection in Ewing Sarcoma Patients: ptDNA and ptRNA in Ewing Sarcoma. J Mol Diagn. 2021 Jul;23(7):872-881. PubMed PMID: 33887462
  • Sopfe J, Marsh R, Ziniel SI, Klosky JL, Chow EJ, Dorsey Holliman B, Peterson PN. Evaluation of the v2.0 Brief Profiles for Sexual Function and Satisfaction PROMIS in Adolescent and Young Adult Childhood Cancer Survivors. J Adolesc Young Adult Oncol. 2021 Aug;10(4):418-424. PubMed PMID: 33136468
  • Macaruso N, Campbell K, Cost C, Sopfe J. Provider Documentation of Tinnitus in Childhood Cancer Survivors. J Pediatr Hematol Oncol. 2021 Jul 1;43(5):e642-e647. PubMed PMID: 33065711
  • Sopfe J, Greffe B, Treece AL. Metastatic NUT Midline Carcinoma Treated With Aggressive Neoadjuvant Chemotherapy, Radiation, and Resection: A Case Report and Review of the Literature. J Pediatr Hematol Oncol. 2021 Jan;43(1):e73-e75. PubMed PMID: 32555032
  • Burns K, Phillips C, Brannigan R, Franklin A, Howell J, Schmidt D, Sopfe J, Appiah LC, Anazodo A. Male pediatric, adolescent, and young adult reproductive survivorship. Pediatr Blood Cancer. 2023 Sep;70 Suppl 5:e28823. PubMed PMID: 37381156
  • Cherven B, Ivankova NV, Spencer JB, Fitzpatrick AM, Burns KC, Demedis J, Hoefgen HR, Mertens AC, Klosky JL. Examining decisional needs and contextual factors influencing fertility status assessment among young female survivors of childhood cancer: A sequential mixed methods study protocol. PLoS One. 2023;18(6):e0286511. PubMed PMID: 37315007
  • Cai CR, Cornelius S, Demedis J, Hagen AM, Abbey-Lambertz M, Armstrong GT, Oeffinger KC, Syrjala KL, Taylor SL, Yi JC, Chow EJ. Experiences of adult survivors of childhood cancer in a randomized cardiovascular health promotion trial: a qualitative report from the Childhood Cancer Survivor Study. J Cancer Surviv. 2023 May 30;:1-9. [Epub ahead of print] PubMed PMID: 37253902
  • Meier KM, Demedis J, Edwards M, Cost NG. Vaginal Rhabdoid Tumor Presenting as Prenatal Lower Urinary Tract Obstruction and Vaginal Mass. Urology. 2023 Jul;177:175-177. PubMed PMID: 36736915
  • Demedis J, Scarbro S, Suresh K, Maloney K, Forlenza GP. Hyperglycemia and Other Glycemic Measures Throughout Therapy for Pediatric Acute Lymphoblastic Leukemia and Lymphoma. J Pediatr Hematol Oncol. 2023 Mar 1;45(2):e154-e160. PubMed PMID: 36715999
  • Cho S, Vigers T, Pyle L, Franklin A, Sopfe J, Jeney F, Forlenza G. Composite Metric of Glycemic Control Q-Score Is Elevated in Pediatric and Adolescent/Young Adult Hematopoietic Stem Cell Transplant Recipients. Diabetes Technol Ther. 2023 Feb;25(2):116-121. PubMed PMID: 36511871
  • Demedis J, Reedy J, Miller K, Hu J, Klosky JL, Dorsey Holliman B, Peterson PN, Chow EJ, Studts C. Testing effectiveness and implementation of a standardized approach to sexual dysfunction screening among adolescent and young adult-aged survivors of childhood cancer: A type I hybrid, mixed methods trial protocol. PLoS One. 2024;19(7):e0305677. PubMed PMID: 39038011
  • Demedis J, Reedy J, Miller K, Hu J, Klosky JL, Holliman BD, Peterson PN, Chow EJ, Studts C. Testing effectiveness and implementation of a standardized approach to sexual dysfunction screening among adolescent and young adult-aged survivors of childhood cancer: A type I hybrid, mixed methods trial protocol: Effectiveness of sexual dysfunction screening among AYA cancer survivors: a study protocol. medRxiv. 2024 Jun 6. PubMed PMID: 38883789
  • Demedis J, Bingen K, Cherven B, Frederick NN, Freyer DR, Levine J, Bhutada JS, Quinn GP, Bober SL, DuVall AS. Development of a Patient-Reported Sexual Health Outcomes Battery for Use in Adolescent and Young Adult Cancer Clinical Trials. J Adolesc Young Adult Oncol. 2024 Jun;13(3):369-373. PubMed PMID: 38569163
  • Goodspeed A, Bodlak A, Duffy AB, Nelson-Taylor S, Oike N, Porfilio T, Shirai R, Walker D, Treece A, Black J, Donaldson N, Cost C, Garrington T, Greffe B, Luna-Fineman S, Demedis J, Lake J, Danis E, Verneris M, Adams DL, Hayashi M. Characterization of transcriptional heterogeneity and novel therapeutic targets using single cell RNA-sequencing of primary and circulating Ewing sarcoma cells. bioRxiv. 2024 Jun 20. PubMed PMID: 38293103
  • Demedis J, Reedy J, Chow EJ, Dorsey Holliman B, Peterson PN, Studts CR. Provider perspectives and recommendations on standardized sexual function screening intervention in adolescent/young adult oncology patients. Pediatr Blood Cancer. 2024 Apr;71(4):e30872. PubMed PMID: 38233999
  • De Castro GC, Slatnick LR, Shannon M, Zhao Z, Jackson K, Smith CM, Whitehurst D, Elliott C, Clark CC, Scott HF, Friedman DL, Demedis J, Esbenshade AJ. Impact of Time-to-Antibiotic Delivery in Pediatric Patients With Cancer Presenting With Febrile Neutropenia. JCO Oncol Pract. 2024 Feb;20(2):228-238. PubMed PMID: 38127868
  • Zhao Z, Patel PA, Slatnick L, Sitthi-Amorn A, Bielamowicz KJ, Nunez FA, Walsh AM, Hess J, Rossoff J, Elgarten C, Myers R, Saab R, Basbous M, Mccormick M, Aftandilian C, Richards R, Nessle CN, Tribble AC, Sheth Bhutada JK, Coven SL, Runco D, Wilkes J, Gurunathan A, Guinipero T, Belsky JA, Lee K, Wong V, Malhotra M, Armstrong A, Jerkins LP, Cross SJ, Fisher L, Stein MT, Wu NL, Yi T, Orgel E, Haeusler GM, Wolf J, Demedis JM, Miller TP, Esbenshade AJ. Prospective External Validation of the Esbenshade Vanderbilt Models Accurately Predicts Bloodstream Infection Risk in Febrile Non-Neutropenic Children With Cancer. J Clin Oncol. 2024 Mar 1;42(7):832-841. PubMed PMID: 38060973
  • Meier KM, Linton A, Baldes C, Demedis J, Cost NG. Peripubertal Presentation of Metastatic Testicular Mixed, Nonseminomatous Germ Cell Tumor. Urology. 2024 Feb;184:e239-e242. PubMed PMID: 37956765
  • Smolik S, Miller AL, Mong DA, Trenbeath Z, Miller KR, Cost C, Demedis J. Incidence and Risk Factors for Brown Adipose Tissue Uptake in PET Imaging in Pediatric Patients. J Pediatr Hematol Oncol. 2024 Jan 1;46(1):e60-e64. PubMed PMID: 37910816
  • Cherven BO, Demedis J, Frederick NN. Sexual Health in Adolescents and Young Adults With Cancer. J Clin Oncol. 2024 Feb 20;42(6):717-724. PubMed PMID: 37856773
  • Cho S, Vigers T, Pyle L, Franklin A, Sopfe J, Jeney F, Forlenza G. Composite Metric of Glycemic Control Q-Score Is Elevated in Pediatric and Adolescent/Young Adult Hematopoietic Stem Cell Transplant Recipients. Diabetes Technol Ther. 2023 Feb;25(2):116-121. PubMed PMID: 36511871
  • Demedis J, Scarbro S, Suresh K, Maloney K, Forlenza GP. Hyperglycemia and Other Glycemic Measures Throughout Therapy for Pediatric Acute Lymphoblastic Leukemia and Lymphoma. J Pediatr Hematol Oncol. 2023 Mar 1;45(2):e154-e160. PubMed PMID: 36715999
  • Meier KM, Demedis J, Edwards M, Cost NG. Vaginal Rhabdoid Tumor Presenting as Prenatal Lower Urinary Tract Obstruction and Vaginal Mass. Urology. 2023 Jul;177:175-177. PubMed PMID: 36736915
  • Cai CR, Cornelius S, Demedis J, Hagen AM, Abbey-Lambertz M, Armstrong GT, Oeffinger KC, Syrjala KL, Taylor SL, Yi JC, Chow EJ. Experiences of adult survivors of childhood cancer in a randomized cardiovascular health promotion trial: a qualitative report from the Childhood Cancer Survivor Study. J Cancer Surviv. 2024 Oct;18(5):1665-1673. PubMed PMID: 37253902
  • Cherven B, Ivankova NV, Spencer JB, Fitzpatrick AM, Burns KC, Demedis J, Hoefgen HR, Mertens AC, Klosky JL. Examining decisional needs and contextual factors influencing fertility status assessment among young female survivors of childhood cancer: A sequential mixed methods study protocol. PLoS One. 2023;18(6):e0286511. PubMed PMID: 37315007
  • Burns K, Phillips C, Brannigan R, Franklin A, Howell J, Schmidt D, Sopfe J, Appiah LC, Anazodo A. Male pediatric, adolescent, and young adult reproductive survivorship. Pediatr Blood Cancer. 2023 Sep;70 Suppl 5:e28823. PubMed PMID: 37381156

Practice Locations

Children's Hospital Colorado Anschutz Medical Campus
13123 East 16th Ave
Aurora, CO 80045
720-777-1234

Hospital Affiliation
  • Children's Hospital Colorado

Center Affiliations

Specialty Information

Specialties
  • Pediatric Hematology / Oncology, Board Certification
Clinical Interests
My focus is on taking care of children, adolescents and young adults with pediatric solid tumors of all types, as well as caring for survivors of pediatric cancers.

Care Philosophy
The privilege of being a part of a patient’s and family’s lives at such a difficult time is something that I take very seriously. While my ultimate goal as an oncologist is to cure my patients of their cancers, I strongly believe in the importance of considering each child and family's whole experience through this difficult journey. It is our duty to work toward reducing harmful side effects both during and after treatment and I strive to consider these short and long term effects at every interaction.