David Albers, PhD
Associate Professor, Biomedical Informatics

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Graduate Schools :
  • MA, University of Wisconsin - Madison (2002)
  • PhD, University of Wisconsin - Madison (2004)
Undergraduate School:
  • BS, University of Wisconsin–Madison (WI) (1998)
Department: Biomedical Informatics

Recognition & Awards

  • Hilldale undergraduate research fellowship, University of Wisconsin (1996)
    I received an award to do undergraduate research.

Publications

  • Sottile PD, Smith B, Stroh JN, Albers DJ, Moss M. Flow-Limited and Reverse-Triggered Ventilator Dyssynchrony Are Associated With Increased Tidal and Dynamic Transpulmonary Pressure. Crit Care Med. 2024 Jan 12. [Epub ahead of print] PubMed PMID: 38214566
  • Stroh JN, Sottile PD, Wang Y, Smith BJ, Bennett TD, Moss M, Albers DJ. Identifying low-dimensional trajectories of mechanically-ventilated patient systems: Empirical phenotypes of joint patient care processes to enhance temporal analysis in ARDS research. medRxiv. 2023 Dec 15. PubMed PMID: 38168309
  • Sottile PD, Smith B, Moss M, Albers DJ. The Development, Optimization, and Validation of Four Different Machine Learning Algorithms to Identify Ventilator Dyssynchrony. medRxiv. 2023 Nov 29. PubMed PMID: 38076801
  • Briggs JK, Gresch A, Marinelli I, Dwulet JM, Albers DJ, Kravets V, Benninger RKP. Beta-cell intrinsic dynamics rather than gap junction structure dictates subpopulations in the islet functional network. Elife. 2023 Nov 29;12. [Epub ahead of print] PubMed PMID: 38018905
  • Wang Y, Stroh JN, Hripcsak G, Low Wang CC, Bennett TD, Wrobel J, Der Nigoghossian C, Mueller SW, Claassen J, Albers DJ. A methodology of phenotyping ICU patients from EHR data: High-fidelity, personalized, and interpretable phenotypes estimation. J Biomed Inform. 2023 Dec;148:104547. PubMed PMID: 37984547
  • Wang Y, Stroh JN, Hripcsak G, Low Wang CC, Bennett TD, Wrobel J, Der Nigoghossian C, Mueller S, Claassen J, Albers DJ. A methodology of phenotyping ICU patients from EHR data: high-fidelity, personalized, and interpretable phenotypes estimation. medRxiv. 2023 Aug 25. PubMed PMID: 37662404
  • Albers D, Sirlanci M, Levine M, Claassen J, Nigoghossian C, Hripcsak G. Interpretable physiological forecasting in the ICU using constrained data assimilation and electronic health record data. J Biomed Inform. 2023 Sep;145:104477. PubMed PMID: 37604272
  • Bilodeaux J, Farooqi H, Osovskaya M, Sosa A, Wallbank A, Knudsen L, Sottile PD, Albers DJ, Smith BJ. Differential effects of two-hit models of acute and ventilator-induced lung injury on lung structure, function, and inflammation. Front Physiol. 2023;14:1217183. PubMed PMID: 37565138
  • Sirlanci M, Levine ME, Low Wang CC, Albers DJ, Stuart AM. A simple modeling framework for prediction in the human glucose-insulin system. Chaos. 2023 Jul 1;33(7). PubMed PMID: 37486667
  • Burgermaster M, Desai PM, Heitkemper EM, Juul F, Mitchell EG, Turchioe M, Albers DJ, Levine ME, Larson D, Mamykina L. Who needs what (features) when? Personalizing engagement with data-driven self-management to improve health equity. J Biomed Inform. 2023 Aug;144:104419. PubMed PMID: 37301528
  • Graham EJ, Elhadad N, Albers D. Reduced model for female endocrine dynamics: Validation and functional variations. Math Biosci. 2023 Apr;358:108979. PubMed PMID: 36792027
  • Stroh JN, Smith BJ, Sottile PD, Hripcsak G, Albers DJ. Hypothesis-driven modeling of the human lung-ventilator system: A characterization tool for Acute Respiratory Distress Syndrome research. J Biomed Inform. 2023 Jan;137:104275. PubMed PMID: 36572279
  • Richter LR, Albert BI, Zhang L, Ostropolets A, Zitsman JL, Fennoy I, Albers DJ, Hripcsak G. Data assimilation on mechanistic models of glucose metabolism predicts glycemic states in adolescents following bariatric surgery. Front Physiol. 2022 Nov 28;13:923704. doi: 10.3389/fphys.2022.923704. PMID: 36518108; PMCID: PMC9744230.
  • Stroh JN, Smith BJ, Sottile PD, Hripcsak G, Albers DJ. Hypothesis-driven modeling of the human lung-ventilator system: A characterization tool for Acute Respiratory Distress Syndrome research. J Biomed Inform. 2023 Jan;137:104275. doi: 10.1016/j.jbi.2022.104275. Epub 2022 Dec 24. PMID: 36572279; PMCID: PMC9788853.
  • Martin B, DeWitt PE, Albers D, Bennett TD. Development of a Pediatric Blood Pressure Percentile Tool for Clinical Decision Support. JAMA Netw Open. 2022 Oct 3;5(10):e2236918. doi: 10.1001/jamanetworkopen.2022.36918. PMID: 36251296; PMCID: PMC9577675.
  • Beta-cell Metabolic Activity Rather than Gap Junction Structure Dictates Subpopulations in the Islet Functional Network Jennifer K. Briggs, Vira Kravets, JaeAnn M. Dwulet, David J. Albers, Richard K. P. Benninger bioRxiv 2022.02.06.479331; doi: https://doi.org/10.1101/2022.02.06.479331
  • Briggs, J., et al. "Quantifying the relationship between emergent islet function, gap junctions, and beta cell dynamics: a network theory approach." DIABETOLOGIA. Vol. 65. No. SUPPL 1. ONE NEW YORK PLAZA, SUITE 4600, NEW YORK, NY, UNITED STATES: SPRINGER, 2022.
  • Hripcsak G, Albers DJ. Evaluating Prediction of Continuous Clinical Values: A Glucose Case Study. Methods Inf Med. 2022 Jun;61(S 01):e35-e44. doi: 10.1055/s-0042-1743170. Epub 2022 Feb 23. PMID: 35196735; PMCID: PMC9246512.
  • Karamched BR, Hripcsak G, Leibel RL, Albers D, Ott W. Delay-induced uncertainty in the glucose-insulin system: Pathogenicity for obesity and type-2 diabetes mellitus. Front Physiol. 2022 Sep 1;13:936101. doi: 10.3389/fphys.2022.936101. PMID: 36117719; PMCID: PMC9476552.
  • Sottile, P. D., et al. "Utilizing Machine Learning and Esophageal Pressure to Detect Ventilator Dyssynchrony and Delineate the Potential for Ventilator Induced Lung Injury." B95. ARDS: WHAT'S THE LATEST AND GREATEST?. American Thoracic Society, 2022. A3435-A3435.
  • Abohtyra RM, Chan CL, Albers DJ, Gluckman BJ. Inferring Insulin Secretion Rate from Sparse Patient Glucose and Insulin Measures. Front Physiol. 2022 Aug 3;13:893862. doi: 10.3389/fphys.2022.893862. PMID: 35991187; PMCID: PMC9384214.
  • Mitchell EG, Tabak EG, Levine ME, Mamykina L, Albers DJ. Enabling personalized decision support with patient-generated data and attributable components. J Biomed Inform. 2021 Jan;113:103639. PubMed PMID: 33316422
  • Stroh JN, Albers DJ, Bennett TD. Personalization and Pragmatism: Pediatric Intracranial Pressure and Cerebral Perfusion Pressure Treatment Thresholds. Pediatr Crit Care Med. 2021 Feb 1;22(2):213-216. PubMed PMID: 33528196
  • Sottile PD, Albers D, DeWitt PE, Russell S, Stroh JN, Kao DP, Adrian B, Levine ME, Mooney R, Larchick L, Kutner JS, Wynia MK, Glasheen JJ, Bennett TD. Real-Time Electronic Health Record Mortality Prediction During the COVID-19 Pandemic: A Prospective Cohort Study. medRxiv. 2021 Jan 15. PubMed PMID: 33469601
  • Agrawal DK, Smith BJ, Sottile PD, Albers DJ. A Damaged-Informed Lung Ventilator Model for Ventilator Waveforms. Front Physiol. 2021;12:724046. PubMed PMID: 34658911
  • Albers DJ, Levine M, Gluckman B, Ginsberg H, Hripcsak G, Mamykina L. Correction: Personalized glucose forecasting for type 2 diabetes using data assimilation. PLoS Comput Biol. 2021 Aug;17(8):e1009325. PubMed PMID: 34415908
  • Fu LH, Knaplund C, Cato K, Perotte A, Kang MJ, Dykes PC, Albers D, Collins Rossetti S. Utilizing timestamps of longitudinal electronic health record data to classify clinical deterioration events. J Am Med Inform Assoc. 2021 Aug 13;28(9):1955-1963. PubMed PMID: 34270710
  • Schnock KO, Kang MJ, Rossetti SC, Garcia J, Lowenthal G, Knaplund C, Chang F, Albers D, Korach TZ, Zhou L, Klann JG, Cato K, Bates DW, Dykes PC. Identifying nursing documentation patterns associated with patient deterioration and recovery from deterioration in critical and acute care settings. Int J Med Inform. 2021 Sep;153:104525. PubMed PMID: 34171662
  • Bennett TD, Russell S, Albers DJ. Neural Networks for Mortality Prediction: Ready for Prime Time?. Pediatr Crit Care Med. 2021 Jun 1;22(6):578-581. PubMed PMID: 34078844
  • Sottile PD, Albers D, DeWitt PE, Russell S, Stroh JN, Kao DP, Adrian B, Levine ME, Mooney R, Larchick L, Kutner JS, Wynia MK, Glasheen JJ, Bennett TD. Real-time electronic health record mortality prediction during the COVID-19 pandemic: a prospective cohort study. J Am Med Inform Assoc. 2021 Oct 12;28(11):2354-2365. PubMed PMID: 33973011
  • Stroh JN, Bennett TD, Kheyfets V, Albers D. Clinical Decision Support for Traumatic Brain Injury: Identifying a Framework for Practical Model-Based Intracranial Pressure Estimation at Multihour Timescales. JMIR Med Inform. 2021 Mar 22;9(3):e23215. PubMed PMID: 33749613
  • Karamched B, Hripcsak G, Albers D, Ott W. Delay-induced uncertainty for a paradigmatic glucose-insulin model. Chaos. 2021 Feb;31(2):023142. PubMed PMID: 33653035
  • Stroh JN, Albers DJ, Bennett TD. Personalization and Pragmatism: Pediatric Intracranial Pressure and Cerebral Perfusion Pressure Treatment Thresholds. Pediatr Crit Care Med. 2021 Feb 1;22(2):213-216. PubMed PMID: 33528196
  • Sottile PD, Albers D, DeWitt PE, Russell S, Stroh JN, Kao DP, Adrian B, Levine ME, Mooney R, Larchick L, Kutner JS, Wynia MK, Glasheen JJ, Bennett TD. Real-Time Electronic Health Record Mortality Prediction During the COVID-19 Pandemic: A Prospective Cohort Study. medRxiv. 2021 Jan 15. PubMed PMID: 33469601
  • Mitchell EG, Tabak EG, Levine ME, Mamykina L, Albers DJ. Enabling personalized decision support with patient-generated data and attributable components. J Biomed Inform. 2021 Jan;113:103639. PubMed PMID: 33316422
  • Rossetti SC, Knaplund C, Albers D, Dykes PC, Kang MJ, Korach TZ, Zhou L, Schnock K, Garcia J, Schwartz J, Fu LH, Klann JG, Lowenthal G, Cato K. Healthcare Process Modeling to Phenotype Clinician Behaviors for Exploiting the Signal Gain of Clinical Expertise (HPM-ExpertSignals): Development and evaluation of a conceptual framework. J Am Med Inform Assoc. 2021 Jun 12;28(6):1242-1251. PubMed PMID: 33624765
  • Burgermaster M, Son JH, Davidson PG, Smaldone AM, Kuperman G, Feller DJ, Burt KG, Levine ME, Albers DJ, Weng C, Mamykina L. A new approach to integrating patient-generated data with expert knowledge for personalized goal setting: A pilot study. Int J Med Inform. 2020 Jul;139:104158. PubMed PMID: 32388157
  • Sottile PD, Albers D, Smith BJ, Moss MM. Ventilator dyssynchrony - Detection, pathophysiology, and clinical relevance: A Narrative review. Ann Thorac Med. 2020 Oct-Dec;15(4):190-198. PubMed PMID: 33381233
  • Fu LH, Schwartz J, Moy A, Knaplund C, Kang MJ, Schnock KO, Garcia JP, Jia H, Dykes PC, Cato K, Albers D, Rossetti SC. Development and validation of early warning score system: A systematic literature review. J Biomed Inform. 2020 May;105:103410. PubMed PMID: 32278089
  • Woldaregay AZ, Launonen IK, Årsand E, Albers D, Holubová A, Hartvigsen G. Toward Detecting Infection Incidence in People With Type 1 Diabetes Using Self-Recorded Data (Part 1): A Novel Framework for a Personalized Digital Infectious Disease Detection System. J Med Internet Res. 2020 Aug 12;22(8):e18911. PubMed PMID: 32784178
  • Woldaregay AZ, Launonen IK, Albers D, Igual J, Årsand E, Hartvigsen G. A Novel Approach for Continuous Health Status Monitoring and Automatic Detection of Infection Incidences in People With Type 1 Diabetes Using Machine Learning Algorithms (Part 2): A Personalized Digital Infectious Disease Detection Mechanism. J Med Internet Res. 2020 Aug 12;22(8):e18912. PubMed PMID: 32784179
  • Sottile PD, Albers D, Smith BJ, Moss MM. Ventilator dyssynchrony - Detection, pathophysiology, and clinical relevance: A Narrative review. Ann Thorac Med. 2020 Oct-Dec;15(4):190-198. PubMed PMID: 33381233
  • Woldaregay AZ, Launonen IK, Albers D, Igual J, Årsand E, Hartvigsen G. A Novel Approach for Continuous Health Status Monitoring and Automatic Detection of Infection Incidences in People With Type 1 Diabetes Using Machine Learning Algorithms (Part 2): A Personalized Digital Infectious Disease Detection Mechanism. J Med Internet Res. 2020 Aug 12;22(8):e18912. PubMed PMID: 32784179
  • Woldaregay AZ, Launonen IK, Årsand E, Albers D, Holubová A, Hartvigsen G. Toward Detecting Infection Incidence in People With Type 1 Diabetes Using Self-Recorded Data (Part 1): A Novel Framework for a Personalized Digital Infectious Disease Detection System. J Med Internet Res. 2020 Aug 12;22(8):e18911. PubMed PMID: 32784178
  • Burgermaster M, Son JH, Davidson PG, Smaldone AM, Kuperman G, Feller DJ, Burt KG, Levine ME, Albers DJ, Weng C, Mamykina L. A new approach to integrating patient-generated data with expert knowledge for personalized goal setting: A pilot study. Int J Med Inform. 2020 Jul;139:104158. PubMed PMID: 32388157
  • Fu LH, Schwartz J, Moy A, Knaplund C, Kang MJ, Schnock KO, Garcia JP, Jia H, Dykes PC, Cato K, Albers D, Rossetti SC. Development and validation of early warning score system: A systematic literature review. J Biomed Inform. 2020 May;105:103410. PubMed PMID: 32278089
  • Roh DJ, Albers DJ, Magid-Bernstein J, Doyle K, Hod E, Eisenberger A, Murthy S, Witsch J, Park S, Agarwal S, Connolly ES, Elkind MSV, Claassen J. Low hemoglobin and hematoma expansion after intracerebral hemorrhage. Neurology. 2019 Jul 23;93(4):e372-e380. PubMed PMID: 31209179
  • Woldaregay AZ, Årsand E, Walderhaug S, Albers D, Mamykina L, Botsis T, Hartvigsen G. Data-driven modeling and prediction of blood glucose dynamics: Machine learning applications in type 1 diabetes. Artif Intell Med. 2019 Jul;98:109-134. PubMed PMID: 31383477
  • Albers DJ, Levine ME, Mamykina L, Hripcsak G. The parameter Houlihan: A solution to high-throughput identifiability indeterminacy for brutally ill-posed problems. Math Biosci. 2019 Oct;316:108242. PubMed PMID: 31454628
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Practice Locations

UCHealth Anschutz Outpatient Pavilion - Anschutz Medical Campus
1635 Aurora Ct
Aurora, CO 80045
720-848-0000

General Information

Graduate Schools:
  • MA, University of Wisconsin - Madison (2002)
  • PhD, University of Wisconsin - Madison (2004)
Undergraduate Schools:
  • BS, University of Wisconsin–Madison (WI) (1998)
Department: Biomedical Informatics
Contact Us
CU Anschutz
Fitzsimons Building

13001 East 17th Place
Campus Box C290
Aurora, CO 80045

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