Christene Huang, PhD

Publications

• Navarro-Alvarez N, Gonçalves BMM, Andrews AR, Sachs DH, Huang CA. A CFA-Induced Model of Inflammatory Skin Disease in Miniature Swine. Int J Inflam. 2018;2018:6916920. PubMed PMID: 30034774
• Wang Z, Louras NJ, Lellouch AG, Pratts SG, Zhang H, Wang H, Huang CA, Cetrulo CL Jr, Madsen JC, Sachs DH, Wang Z. Dosing optimization of CCR4 immunotoxin for improved depletion of CCR4( ) Treg in nonhuman primates. Mol Oncol. 2018 Aug;12(8):1374-1382. PubMed PMID: 29873181
• Navarro-Alvarez N, Goncalves B, Andrews AR, Wang Z, Wang Z, Harrington E, Shah J, Sachs DH, Eliaz I, Huang CA. The effects of galectin-3 depletion apheresis on induced skin inflammation in a porcine model. J Clin Apher. 2018 Aug;33(4):486-493. PubMed PMID: 29572917
• Andrews AR, Fernandes AD, Brownmiller SE, Hanna Y, Fisher MC, Huang CA. Blocking extracellular Galectin-3 in patients with osteoarthritis. Contemp Clin Trials Commun. 2020 Mar;17:100500. PubMed PMID: 31872160
• Andrews AR, Wang Z, Wilkinson RA, Fishman JA, Sachs DH, Navarro-Alvarez N, Huang CA. Development of transplantable B-cell lymphomas in the MHC-defined miniature swine model. Cancer Cell Int. 2019;19:236. PubMed PMID: 31516393
• Duran-Struuck R, Huang CA, Matar AJ. Cellular Therapies for the Treatment of Hematological Malignancies; Swine Are an Ideal Preclinical Model. Front Oncol. 2019;9:418. PubMed PMID: 31293961
• Schenk M, Matar AJ, Hanekamp I, Hawley RJ, Huang CA, Duran-Struuck R. Development of a Transplantable GFP B-Cell Lymphoma Tumor Cell Line From MHC-Defined Miniature Swine: Potential for a Large Animal Tumor Model. Front Oncol. 2019;9:209. PubMed PMID: 31001475
• Wang Z, Huang CA. A PD-1-specific toxin suppresses autoimmunity. Nat Biomed Eng. 2019 Apr;3(4):253-254. PubMed PMID: 30952985
• DeFilipp Z, Navarro-Alvarez N, Li S, Andrews AR, Johnson A, Chen Y-B, Ho VT, Ritz J, Spitzer TR, Huang CA. Elevated plasma galectin-3 concentrations in recipients of allogeneic hematopoietic cell transplantation. Clinical Hematology International 2019; 1 (4): 201-204.
• Lizardo-Thiebaud MJ, Cervantes-Alvarez E, Limon-de la Rosa N, Tejeda-Dominguez F, Palacios-Jimenez M, Méndez-Guerrero O, Delaye-Martinez M, Rodriguez-Alvarez F, Romero-Morales B, Liu WH, Huang CA, Kershenobich D, Navarro-Alvarez N. Direct or Collateral Liver Damage in SARS-CoV-2-Infected Patients. Semin Liver Dis. 2020 Aug;40(3):321-330. PubMed PMID: 32886936
• Wang H, Wang Z, Zhang H, Qi Z, Johnson AC, Mathes D, Pomfret EA, Rubin E, Huang CA, Wang Z. Bispecific human IL2-CCR4 immunotoxin targets human cutaneous T-cell lymphoma. Mol Oncol. 2020 May;14(5):991-1000. PubMed PMID: 32107846
• Andrews AR, Fernandes AD, Brownmiller SE, Hanna Y, Fisher MC, Huang CA. Blocking extracellular Galectin-3 in patients with osteoarthritis. Contemp Clin Trials Commun. 2020 Mar;17:100500. PubMed PMID: 31872160
• Andrews AR, Wang Z, Wilkinson RA, Fishman JA, Sachs DH, Navarro-Alvarez N, Huang CA. Development of transplantable B-cell lymphomas in the MHC-defined miniature swine model. Cancer Cell Int. 2019;19:236. PubMed PMID: 31516393
• Duran-Struuck R, Huang CA, Matar AJ. Cellular Therapies for the Treatment of Hematological Malignancies; Swine Are an Ideal Preclinical Model. Front Oncol. 2019;9:418. PubMed PMID: 31293961
• Schenk M, Matar AJ, Hanekamp I, Hawley RJ, Huang CA, Duran-Struuck R. Development of a Transplantable GFP B-Cell Lymphoma Tumor Cell Line From MHC-Defined Miniature Swine: Potential for a Large Animal Tumor Model. Front Oncol. 2019;9:209. PubMed PMID: 31001475
• Wang Z, Huang CA. A PD-1-specific toxin suppresses autoimmunity. Nat Biomed Eng. 2019 Apr;3(4):253-254. PubMed PMID: 30952985
• Yang JH, Johnson AC, Colakoglu S, Huang CA, Mathes DW. Clinical and preclinical tolerance protocols for vascularized composite allograft transplantation. Arch Plast Surg. 2021 Nov;48(6):703-713. PubMed PMID: 34818720
• Anderson JB, Foglio A, Harrant AB, Huang CA, Hultman CS, Mathes DW, Chong TW. Scoping Review of Therapeutic Strategies for Keloids and Hypertrophic Scars. Plast Reconstr Surg Glob Open. 2021 Mar;9(3):e3469. PubMed PMID: 33786262
• Krüger L, Böttger J, Huang CA, Denner J. Absence of porcine endogenous retrovirus (PERV) production from pig lymphoma cell lines. Virus Res. 2021 Apr 2;295:198286. PubMed PMID: 33418025
• Kim S, Shukla RK, Yu H, Baek A, Cressman SG, Golconda S, Lee GE, Choi H, Reneau JC, Wang Z, Huang CA, Liyanage NPM, Kim S. CD3e-immunotoxin spares CD62L(lo) Tregs and reshapes organ-specific T-cell composition by preferentially depleting CD3e(hi) T cells. Front Immunol. 2022;13:1011190. PubMed PMID: 36389741
• Kim S, Shukla RK, Kim E, Cressman SG, Yu H, Baek A, Choi H, Kim A, Sharma A, Wang Z, Huang CA, Reneau JC, Boyaka PN, Liyanage NPM, Kim S. Comparison of CD3e Antibody and CD3e-sZAP Immunotoxin Treatment in Mice Identifies sZAP as the Main Driver of Vascular Leakage. Biomedicines. 2022 May 24;10(6). PubMed PMID: 35740248
• Witthauer L, Roussakis E, Cascales JP, Goss A, Li X, Cralley A, Yoeli D, Moore HB, Wang Z, Wang Y, Li B, Huang CA, Moore EE, Evans CL. Development and in-vivo validation of a portable phosphorescence lifetime-based fiber-optic oxygen sensor. Sci Rep. 2023 Sep 7;13(1):14782. PubMed PMID: 37679415
• Yoeli D, Mack CL, Luo Y, Chaidez A, Limon-de la Rosa N, Wang Z, Cervantes-Alvarez E, Huang CA and Navarro-Alvarez N. Galectin-3 in Biliary Atresia and Other Pediatric Cholestatic Liver Diseases. Hepatology Research 2023; in press.
• Ng PK, Yoeli D, Huang J, Luo Y, Wang Y, Li B, Wang Z, Schold J, Jain S, Su A-J, Mathes DM, Washington KM, Farkash E, Jani AH, Huang CA. Successful Extension of Vascularized Composite Allograft Perfusion Cold Storage to 24 Hours in a Rat Hind Limb Transplant Model. Transplantation Direct 2023; in press.
• Mavri M, Kubale V, Depledge DP, Zuo J, Huang CA, Breuer J, Vrecl M, Jarvis MA, Jovicic EJ, Petan T, Ehlers B, Rosenkilde MM, Spiess K. Epstein-Barr Virus-Encoded BILF1 Orthologues From Porcine Lymphotropic Herpesviruses Display Common Molecular Functionality. Front Endocrinol (Lausanne). 2022;13:862940. PubMed PMID: 35721730
• Caitlin Blades, Nathaly Limon De La Rosa, Bing Li, Yong Wang, An-Jey Su, Alexis Crawley, Ernest E. Moore, Kia M. Washington, Christene A. Huang. Early retinal disruption following traumatic brain injury in swine. VISION INJURY RESEARCH FORUM (VIRF) 7 APRIL 2023 Boston, MA
• Muñoz-Vergara D, Grabowska W, Yeh GY, Khalsa SB, Schreiber KL, Huang CA, Zavacki AM, Wayne PM. A systematic review of in vivo stretching regimens on inflammation and its relevance to translational yoga research. PLoS One. 2022;17(6):e0269300. PubMed PMID: 35648793
• Zari Dumanian, Julia B. Slade, Nalu Navarro-Alvarez, Zhaohui Wang, David W. Mathes, Mark Greyson, Yong Wang, Bing Li, Kia M. Washington, Caitlin Blades, Paula Arrowsmith, Evan Farkash, Conor L. Evans, Christene A. Huang. ADVANCEMENT OF A TISSUE OXYGENATION MEASUREMENT DEVICE AND EVALUATION OF GALECTIN-3 AS NOVEL NONINVASIVE PROGNOSTIC BIOMARKERS FOR MONITORING VASCULARIZED COMPOSITE ALLOGRAFT REJECTION: DEVELOPMENT OF THE PORCINE MODEL. August 14-17, 2023, Military Health Science Research Symposium, Kissimmee, FL.
• Po’okela Ng, Yuhuan Luo, Dor Yoeli, Yong Wang, Bing Li, Li Lu, Zhaohui Wang, Joy Huang, Paula Arrowsmith, Swati Jain, An-Jey A. Su, David M. Mathes, Kia M. Washington, Evan Farkash, Alkesh Jani, Christene A. Huang. SUCCESSFUL EXTENSION OF VASCULARIZED COMPOSITE ALLOGRAFT PERFUSION COLD STORAGE TO 24 HOURS IN A RAT HIND LIMB TRANSPLANT MODEL. August 14-17, 2023, Military Health Science Research Symposium, Kissimmee, FL.
• Yuhuan Luo, Swati Jain, Dor Yoeli, Li Lu, Po’okela Ng, An-Jey A. Su, Kia M. Washington, Evan Farkash, Alkesh Jani, Christene A. Huang. ANTI-APOPTOSIS AND NECROSIS EFFECT OF NECROSTATIN-1 IN SKIN AND MUSCLE CELL LINES SUBJECTED TO PROLONGED COLD STORAGE AND REWARMING: IMPLICATIONS FOR VASCULARIZED COMPOSITE ALLOGRAFT PRESERVATION. August 14, 2023, Oral Presentation, Military Health Science Research Symposium, Kissimmee, FL.
• Cervantes-Alvarez E, Limon-de la Rosa N, Vilatoba M, Pérez-Monter C, Hurtado-Gomez S, Martinez-Cabrera C, Argemi J, Alatorre-Arenas E, Yarza-Regalado S, Tejeda-Dominguez F, Lizardo-Thiebaud MJ, Mendez-Guerrero O, Gamboa-Dominguez A, Aguilar-Salinas CA, Huang CA, Kershenobich D, Bataller R, Torre A, Navarro-Alvarez N. Galectin-3 is overexpressed in advanced cirrhosis and predicts post-liver transplant infectious complications. Liver Int. 2022 Oct;42(10):2260-2273. PubMed PMID: 35635536
• Cervantes-Alvarez E, la Rosa NL, la Mora MS, Valdez-Sandoval P, Palacios-Jimenez M, Rodriguez-Alvarez F, Vera-Maldonado BI, Aguirre-Aguilar E, Escobar-Valderrama JM, Alanis-Mendizabal J, Méndez-Guerrero O, Tejeda-Dominguez F, Torres-Ruíz J, Gómez-Martín D, Colborn KL, Kershenobich D, Huang CA, Navarro-Alvarez N. Galectin-3 as a potential prognostic biomarker of severe COVID-19 in SARS-CoV-2 infected patients. Sci Rep. 2022 Feb 3;12(1):1856. PubMed PMID: 35115644