Marco Del Chiaro, MD
Professor, Surgery-Surgical Oncology

Photo
Medical School:
  • MD, University of Pisa, Italy (1997)
Languages: English, Italian, Swedish, French
Department: Surgery-Surgical Oncology

Professional Titles

  • Division Chief, Surgical Oncology
  • Clinical Director, Hepato-Pancreato-Biliary Program

Teaching

  • Professor (2018)
    School of Medicine, Surgery
    Pancreas, Liver, Stomach, Adrenal, Colorectal, Sarcoma, Cancer Surgery, Immunotherapy

Publications

  • Stoop TF, Theijse RT, Seelen LWF, Groot Koerkamp B, van Eijck CHJ, Wolfgang CL, van Tienhoven G, van Santvoort HC, Molenaar IQ, Wilmink JW, Del Chiaro M, Katz MHG, Hackert T, Besselink MG. Preoperative chemotherapy, radiotherapy and surgical decision-making in patients with borderline resectable and locally advanced pancreatic cancer. Nat Rev Gastroenterol Hepatol. 2023 Nov 30. [Epub ahead of print] PubMed PMID: 38036745
  • Fong ZV, Zwart MJW, Gorris M, Voermans RP, van Wanrooij RLJ, Wielenga T, Del Chiaro M, Arnelo U, Daams F, Busch OR, Besselink MG. Intraoperative Pancreatoscopy During Robotic Pancreatoduodenectomy and Robotic Distal Pancreatectomy for Intraductal Papillary Mucinous Neoplasm with Involvement of the Main Pancreatic Duct. Ann Surg Open. 2023 Jun;4(2):e283. PubMed PMID: 37601466
  • Stoop TF, Ghorbani P, Theijse RT, van Veldhuisen CL, DeVries JH, Groot Koerkamp B, van Santvoort HC, Molenaar IQ, Busch OR, Del Chiaro M, Besselink MG. Comment on: Pancreatectomy With Islet-Autotransplantation As Alternative for Pancreatoduodenectomy in Patients With a High-Risk for Postoperative Pancreatic Fistula: The Jury Is Still Out. Ann Surg Open. 2023 Mar;4(1):e247. PubMed PMID: 37600874
  • Stoop TF, von Gohren A, Engstrand J, Sparrelid E, Gilg S, Del Chiaro M, Ghorbani P. Risk Factors, Management, and Outcome of Gastric Venous Congestion After Total Pancreatectomy: An Underestimated Complication Requiring Standardized Identification, Grading, and Management. Ann Surg Oncol. 2023 Nov;30(12):7700-7711. PubMed PMID: 37596448
  • Stoop TF, von Gohren A, Engstrand J, Sparrelid E, Gilg S, Del Chiaro M, Ghorbani P. ASO Author Reflections: Gastric Venous Congestion After Total Pancreatectomy is an Underestimated Complication. Ann Surg Oncol. 2023 Nov;30(12):7758-7759. PubMed PMID: 37561344
  • Stoop TF, von Gohren A, Engstrand J, Sparrelid E, Gilg S, Del Chiaro M, Ghorbani P. ASO Visual Abstract: Risk Factors, Management, and Outcome of Gastric Venous Congestion After Total Pancreatectomy: An Underestimated Complication Requiring Standardized Identification, Grading, and Management. Ann Surg Oncol. 2023 Nov;30(12):7768-7769. PubMed PMID: 37543557
  • Hashimoto D, Satoi S, Fujii T, Sho M, He J, Hackert T, Del Chiaro M, Jang JY, Gulla A, Yoon YS, Shan YS, Lou W, Valente R, Furuse J, Oba A, Nagai M, Terai T, Tanaka H, Sakai A, Yamamoto T, Yamaki S, Matsumoto I, Murakami Y, Takaori K, Takeyama Y. Is surgical resection justified for pancreatic ductal adenocarcinoma with distant abdominal organ metastasis? A position paper by experts in pancreatic surgery at the Joint Meeting of the International Association of Pancreatology (IAP) & the Japan Pancreas Society (JPS) 2022 in Kyoto. Pancreatology. 2023 Sep;23(6):682-688. PubMed PMID: 37507301
  • Stuart CM, Kirsch MJ, Zhuang Y, Meguid CL, Sugawara T, Colborn KL, Messersmith W, Lieu C, Gleisner AL, Del Chiaro M, Schulick RD, Meguid RA. Pulmonary metastasectomy is associated with survival after lung-only recurrence in pancreatic cancer. Surgery. 2023 Sep;174(3):654-659. PubMed PMID: 37391327
  • Karam E, Hollenbach M, Abou Ali E, Auriemma F, Anderloni A, Barbier L, Belfiori G, Caillol F, Crippa S, Del Chiaro M, De Ponthaud C, Dahel Y, Falconi M, Giovannini M, Heling D, Inoue Y, Jarnagin WR, Leung G, Lupinacci RM, Mariani A, Masaryk V, Miksch RC, Musquer N, Napoleon B, Oba A, Partelli S, Petrone MC, Prat F, Repici A, Sauvanet A, Salzmann K, Schattner MA, Schulick R, Schwarz L, Soares K, Souche FR, Truant S, Vaillant JC, Wang T, Wedi E, Werner J, Weismüller TJ, Wichmann D, Will U, Zaccari P, Gulla A, Heise C, Regner S, Gaujoux S. Endoscopic and Surgical Management of Non-Metastatic Ampullary Neuroendocrine Neoplasia: A Multi-Institutional Pancreas2000/EPC Study. Neuroendocrinology. 2023;113(10):1024-1034. PubMed PMID: 37369186
  • Oba A, Del Chiaro M, Fujii T, Okano K, Stoop TF, Wu YHA, Maekawa A, Yoshida Y, Hashimoto D, Sugawara T, Inoue Y, Tanabe M, Sho M, Sasaki T, Takahashi Y, Matsumoto I, Sasahira N, Nagakawa Y, Satoi S, Schulick RD, Yoon YS, He J, Jang JY, Wolfgang CL, Hackert T, Besselink MG, Takaori K, Takeyama Y. "Conversion surgery" for locally advanced pancreatic cancer: A position paper by the study group at the joint meeting of the International Association of Pancreatology (IAP) & Japan Pancreas Society (JPS) 2022. Pancreatology. 2023 Sep;23(6):712-720. PubMed PMID: 37336669
  • Arnelo U, Valente R, Scandavini CM, Halimi A, Mucelli RMP, Rangelova E, Svensson J, Schulick RD, Torphy RJ, Fagerström N, Moro CF, Vujasinovic M, Matthias Löhr J, Del Chiaro M. Intraoperative pancreatoscopy can improve the detection of skip lesions during surgery for intraductal papillary mucinous neoplasia: A pilot study. Pancreatology. 2023 Sep;23(6):704-711. PubMed PMID: 37336668
  • Sugawara T, Rodriguez Franco S, Sherman S, Torphy RJ, Colborn K, Franklin O, Ishida J, Grandi S, Al-Musawi MH, Gleisner A, Schulick RD, Del Chiaro M. Neoadjuvant Chemotherapy versus Upfront Surgery for Resectable Pancreatic Adenocarcinoma: An Updated Nationwide Study. Ann Surg. 2023 May 25. [Epub ahead of print] PubMed PMID: 37226812
  • Stoop TF, Bergquist E, Theijse RT, Hempel S, van Dieren S, Sparrelid E, Distler M, Hackert T, Besselink MG, Del Chiaro M, Ghorbani P. Systematic Review and Meta-analysis of the Role of Total Pancreatectomy as an Alternative to Pancreatoduodenectomy in Patients at High Risk for Postoperative Pancreatic Fistula: Is it a Justifiable Indication?. Ann Surg. 2023 Oct 1;278(4):e702-e711. PubMed PMID: 37161977
  • Sugawara T, Rodriguez Franco S, Franklin O, Kirsch MJ, Colborn K, Del Chiaro M, Schulick RD. Management of Localized Small and Large Cell Pancreatic Neuroendocrine Carcinoma in the National Cancer Database. J Am Coll Surg. 2023 May 5. [Epub ahead of print] PubMed PMID: 37146214
  • Gulla A, Ignatavicius P, Correa C, Inohue Y, Hashimoto D, Ban D, Heger U, Wagner D, Xie Q, Shen P, Michel AL, Lerut J, Del Chiaro M, Hackert T, Wolfgang CL, He J, Kingham P, Pawlik TM, Satoi S, Schemmer P, Strupas K, Siriwardena AK. Academic value and impact of continuous global academic learning: the International HPB surgery journal club concept. HPB (Oxford). 2023 Aug;25(8):980-982. PubMed PMID: 37037718
  • Djoumi Y, Sadr-Azodi O, Vujasinovic M, Del Chiaro M, Sparrelid E, Ghorbani P, Holmberg M. Pre-emptive resection for intraductal papillary mucinous neoplasia - Long-term outcome is similar between non-invasive and early invasive lesions in a tertiary single center. Pancreatology. 2023 Jun;23(4):389-395. PubMed PMID: 37002181
  • Sugawara T, Rodriguez Franco S, Kirsch MJ, Colborn KL, Ishida J, Grandi S, Al-Musawi MH, Gleisner A, Del Chiaro M, Schulick RD. Evaluation of Survival Following Surgical Resection for Small Nonfunctional Pancreatic Neuroendocrine Tumors. JAMA Netw Open. 2023 Mar 1;6(3):e234096. PubMed PMID: 36976561
  • Ziogas IA, Rodriguez Franco S, Schmoke N, Meguid C, Murphy C, Al-Musawi M, Alexopoulos SP, Schulick RD, Del Chiaro M. Comparison of Invasive Pancreatic Ductal Adenocarcinoma versus Intraductal Papillary Mucinous Neoplasm: A National Cancer Database Analysis. Cancers (Basel). 2023 Feb 13;15(4). PubMed PMID: 36831527
  • van Huijgevoort NCM, Hoogenboom SAM, Lekkerkerker SJ, Busch OR, Del Chiaro M, Fockens P, Somers I, Verheij J, Voermans RP, Besselink MG, van Hooft JE. Diagnostic accuracy of the AGA, IAP, and European guidelines for detecting advanced neoplasia in intraductal papillary mucinous neoplasm/neoplasia. Pancreatology. 2023 Apr;23(3):251-257. PubMed PMID: 36805049
  • Madsen HJ, Carmichael H, Reinicke T, Gleisner AL, Del Chiaro M, Schulick RD, Stewart CL. Cannabis use and post-operative complications in patients undergoing pancreatic resection. HPB (Oxford). 2023 Apr;25(4):431-438. PubMed PMID: 36740564
  • Sugawara T, Franco SR, Ishida J, Kalra A, Saben JL, Gálvez KN, Kirsch MJ, Al-Musawi MH, Kaplan B, Pomfret EA, Schulick RD, Del Chiaro M. Prevalence and progression of intraductal papillary mucinous neoplasms of the pancreas in solid organ transplant recipients: A systematic review. Am J Transplant. 2023 Mar;23(3):429-436. PubMed PMID: 36695699
  • Ziogas IA, Rallis KS, Tasoudis PT, Moris D, Schulick RD, Del Chiaro M. Management and outcomes of mixed adenoneuroendocrine carcinoma of the ampulla of Vater: A systematic review and pooled analysis of 56 patients. Eur J Surg Oncol. 2023 Apr;49(4):682-687. PubMed PMID: 36646615
  • Karam E, Hollenbach M, Ali EA, Auriemma F, Gulla A, Heise C, Regner S, Gaujoux S, Regimbeau JM, Kähler G, Seyfried S, Vaillant JC, De Ponthaud C, Sauvanet A, Birnbaum D, Regenet N, Truant S, Pérez-Cuadrado-Robles E, Bruzzi M, Lupinacci RM, Brunel M, Belfiori G, Barbier L, Salamé E, Souche FR, Schwarz L, Maggino L, Salvia R, Gagniére J, Del Chiaro M, Leung G, Hackert T, Kleemann T, Paik WH, Caca K, Dugic A, Muehldorfer S, Schumacher B, Albers D. Outcomes of rescue procedures in the management of locally recurrent ampullary tumors: A Pancreas 2000/EPC study. Surgery. 2023 May;173(5):1254-1262. PubMed PMID: 36642655
  • Pozzi Mucelli RM, Moro CF, Del Chiaro M, Valente R, Blomqvist L, Papanikolaou N, Löhr JM, Kartalis N. Publisher Correction: Branch-duct intraductal papillary mucinous neoplasm (IPMN): Are cyst volumetry and other novel imaging features able to improve malignancy prediction compared to well-established resection criteria?. Eur Radiol. 2023 Apr;33(4):3005-3006. PubMed PMID: 36513880
  • Sugawara T, Rodriguez Franco S, Sherman S, Kirsch MJ, Colborn K, Ishida J, Grandi S, Al-Musawi MH, Gleisner A, Schulick RD, Del Chiaro M. Association of Adjuvant Chemotherapy in Patients With Resected Pancreatic Adenocarcinoma After Multiagent Neoadjuvant Chemotherapy. JAMA Oncol. 2023 Mar 1;9(3):316-323. PubMed PMID: 36480190
  • Moyer AM, Madsen H, Johnson J, Del Chiaro M, Gleisner A, Lieu CH, Tevis S, Stewart CL. Informational Needs of Surgical Oncology Patients: A Cross-Sectional Patient Survey. J Surg Res. 2023 Mar;283:771-777. PubMed PMID: 36470202
  • Tamburrino D, Cortesi P, Facchetti R, de Pretis N, Pérez-Cuadrado-Robles E, Uribarri-Gonzalez L, Ateeb Z, Belfiori G, Arcidiacono PG, Mantovani LG, Del Chiaro M, Laukkarinen J, Falconi M, Crippa S, Capurso G. Real-world costs and dynamics of surveillance in patients who underwent surgery for low-risk branch duct intraductal papillary mucinous neoplasms. Eur J Surg Oncol. 2023 Jan;49(1):137-141. PubMed PMID: 36085119
  • Kim HS, Song W, Choo W, Lee S, Han Y, Bassi C, Salvia R, Marchegiani G, Wolfgang CL, He J, Blair AB, Kluger MD, Su GH, Kim SC, Song KB, Yamamoto M, Hatori T, Yang CY, Yamaue H, Hirono S, Satoi S, Fujii T, Hirano S, Lou W, Hashimoto Y, Shimizu Y, Del Chiaro M, Valente R, Lohr M, Choi DW, Choi SH, Heo JS, Motoi F, Matsumoto I, Lee WJ, Kang CM, Shyr YM, Wang SE, Han HS, Yoon YS, Besselink MG, van Huijgevoort NCM, Sho M, Nagano H, Kim SG, Honda G, Yang Y, Yu HC, Yang JD, Chung JC, Nagakawa Y, Seo HI, Lee S, Kim H, Kwon W, Park T, Jang JY. Development, validation, and comparison of a nomogram based on radiologic findings for predicting malignancy in intraductal papillary mucinous neoplasms of the pancreas: An international multicenter study. J Hepatobiliary Pancreat Sci. 2023 Jan;30(1):133-143. PubMed PMID: 33811460
  • Oba A, Wu YHA, Colborn KL, Karam SD, Meguid C, Al-Musawi MH, Bao QR, Gleisner AL, Ahrendt S, Schulick RD, Del Chiaro M. Comparing neoadjuvant chemotherapy with or without radiation therapy for pancreatic ductal adenocarcinoma: National Cancer Database cohort analysis. Br J Surg. 2022 Feb 8. [Epub ahead of print] PubMed PMID: 35136963
  • Valente R, Zarantonello L, Del Chiaro M, Vujasinovic M, Baldaque Silva F, Scandavini CM, Rangelova E, Vespasiano F, Anzillotti G, Löhr JM, Arnelo U. Lumen apposing metal stents vs double pigtail plastic stents for the drainage of pancreatic walled-off necrosis. Minerva Gastroenterol (Torino). 2022 Feb 3. [Epub ahead of print] PubMed PMID: 35112820
  • Stoop TF, Ghorbani P, Scholten L, Bergquist E, Ateeb Z, van Dieren S, Holmberg M, Besselink MG, Sparrelid E, Del Chiaro M. Total pancreatectomy as an alternative to high-risk pancreatojejunostomy after pancreatoduodenectomy: a propensity score analysis on surgical outcome and quality of life. HPB (Oxford). 2022 Jan 1. [Epub ahead of print] PubMed PMID: 35031280
  • Oba A, Croce C, Hosokawa P, Meguid C, Torphy RJ, Al-Musawi MH, Ahrendt S, Gleisner A, Schulick RD, Del Chiaro M. Prognosis Based Definition of Resectability in Pancreatic Cancer: A Road Map to New Guidelines. Ann Surg. 2022 Jan 1;275(1):175-181. PubMed PMID: 32149822
  • Pozzi Mucelli RM, Moro CF, Del Chiaro M, Valente R, Blomqvist L, Papanikolaou N, Löhr JM, Kartalis N. Publisher Correction: Branch-duct intraductal papillary mucinous neoplasm (IPMN): Are cyst volumetry and other novel imaging features able to improve malignancy prediction compared to well-established resection criteria?. Eur Radiol. 2022 Dec 13. [Epub ahead of print] PubMed PMID: 36513880
  • Sugawara T, Rodriguez Franco S, Sherman S, Kirsch MJ, Colborn K, Ishida J, Grandi S, Al-Musawi MH, Gleisner A, Schulick RD, Del Chiaro M. Association of Adjuvant Chemotherapy in Patients With Resected Pancreatic Adenocarcinoma After Multiagent Neoadjuvant Chemotherapy. JAMA Oncol. 2022 Dec 8. [Epub ahead of print] PubMed PMID: 36480190
  • Moyer AM, Madsen H, Johnson J, Del Chiaro M, Gleisner A, Lieu CH, Tevis S, Stewart CL. Informational Needs of Surgical Oncology Patients: A Cross-Sectional Patient Survey. J Surg Res. 2022 Dec 2;283:771-777. [Epub ahead of print] PubMed PMID: 36470202
  • Stoop TF, Fröberg K, Sparrelid E, Del Chiaro M, Ghorbani P. Surgical management of severe pancreatic fistula after pancreatoduodenectomy: a comparison of early versus late rescue pancreatectomy. Langenbecks Arch Surg. 2022 Dec;407(8):3467-3478. PubMed PMID: 36344875
  • Oba A, Wu YHA, Schulick R, Del Chiaro M. Author response to: Comment on: Comparing neoadjuvant chemotherapy with or without radiation therapy for pancreatic ductal adenocarcinoma: National Cancer Database cohort analysis. Br J Surg. 2022 Dec 13;110(1):112. PubMed PMID: 36245252
  • Tamburrino D, Cortesi P, Facchetti R, de Pretis N, Pérez-Cuadrado-Robles E, Uribarri-Gonzalez L, Ateeb Z, Belfiori G, Arcidiacono PG, Mantovani LG, Del Chiaro M, Laukkarinen J, Falconi M, Crippa S, Capurso G. Real-world costs and dynamics of surveillance in patients who underwent surgery for low-risk branch duct intraductal papillary mucinous neoplasms. Eur J Surg Oncol. 2022 Aug 31. [Epub ahead of print] PubMed PMID: 36085119
  • Del Chiaro M, Kirsch MJ, Schulick R. Commentary on: Multi-institutional Validation Study of Cyst Fluid Protein Biomarkers in Patients With Cystic Lesions of the Pancreas. Ann Surg. 2022 Aug 1;276(2):e133. PubMed PMID: 35797412
  • Tamburrino D, de Pretis N, Pérez-Cuadrado-Robles E, Uribarri-Gonzalez L, Ateeb Z, Belfiori G, Maisonneuve P, Capurso G, Vanella G, Petrone MC, Arcidiacono PG, Vaalavuo Y, Frulloni L, Dominguez-Muñoz JE, Deprez PH, Falconi M, Del Chiaro M, Crippa S, Laukkarinen J. Identification of patients with branch-duct intraductal papillary mucinous neoplasm and very low risk of cancer: multicentre study. Br J Surg. 2022 Jun 14;109(7):617-622. PubMed PMID: 35511697
  • Valente R, Crippa S, Arnelo U, Vanella G, Zerboni G, Zarantonello L, Fogliati A, Arcidiacono PG, Vujasinovic M, Lohr JM, Falconi M, Capurso G, Del Chiaro M. The use of ace inhibitors influences the risk of progression of BD-IPMNs under follow-up. Pancreatology. 2022 May;22(4):516-524. PubMed PMID: 35431111
  • Gaiser RA, Pessia A, Ateeb Z, Davanian H, Moro CF, Alkharaan H, Healy K, Ghazi S, Arnelo U, Valente R, Velagapudi V, Chen MS, Del Chiaro M. Author Correction: Integrated targeted metabolomic and lipidomic analysis: A novel approach to classifying early cystic precursors to invasive pancreatic cancer. Sci Rep. 2022 Mar 28;12(1):5281. PubMed PMID: 35347146
  • Pozzi Mucelli RM, Moro CF, Del Chiaro M, Valente R, Blomqvist L, Papanikolaou N, Löhr JM, Kartalis N. Branch-duct intraductal papillary mucinous neoplasm (IPMN): Are cyst volumetry and other novel imaging features able to improve malignancy prediction compared to well-established resection criteria?. Eur Radiol. 2022 Aug;32(8):5144-5155. PubMed PMID: 35275259
  • Oba A, Wu YHA, Colborn KL, Karam SD, Meguid C, Al-Musawi MH, Bao QR, Gleisner AL, Ahrendt S, Schulick RD, Del Chiaro M. Comparing neoadjuvant chemotherapy with or without radiation therapy for pancreatic ductal adenocarcinoma: National Cancer Database cohort analysis. Br J Surg. 2022 Apr 19;109(5):450-454. PubMed PMID: 35136963
  • Valente R, Zarantonello L, Del Chiaro M, Vujasinovic M, Baldaque Silva F, Scandavini CM, Rangelova E, Vespasiano F, Anzillotti G, Löhr JM, Arnelo U. Lumen apposing metal stents vs double pigtail plastic stents for the drainage of pancreatic walled-off necrosis. Minerva Gastroenterol (Torino). 2022 Feb 3. [Epub ahead of print] PubMed PMID: 35112820
  • Stoop TF, Ghorbani P, Scholten L, Bergquist E, Ateeb Z, van Dieren S, Holmberg M, Besselink MG, Sparrelid E, Del Chiaro M. Total pancreatectomy as an alternative to high-risk pancreatojejunostomy after pancreatoduodenectomy: a propensity score analysis on surgical outcome and quality of life. HPB (Oxford). 2022 Aug;24(8):1261-1270. PubMed PMID: 35031280
  • Stoop TF, Fröberg K, Sparrelid E, Del Chiaro M, Ghorbani P. Surgical management of severe pancreatic fistula after pancreatoduodenectomy: a comparison of early versus late rescue pancreatectomy. Langenbecks Arch Surg. 2022 Dec;407(8):3467-3478. PubMed PMID: 36344875
  • Oba A, Wu YHA, Schulick R, Del Chiaro M. Author response to: Comment on: Comparing neoadjuvant chemotherapy with or without radiation therapy for pancreatic ductal adenocarcinoma: National Cancer Database cohort analysis. Br J Surg. 2022 Dec 13;110(1):112. PubMed PMID: 36245252
  • Del Chiaro M, Kirsch MJ, Schulick R. Commentary on: Multi-institutional Validation Study of Cyst Fluid Protein Biomarkers in Patients With Cystic Lesions of the Pancreas. Ann Surg. 2022 Aug 1;276(2):e133. PubMed PMID: 35797412
  • Tamburrino D, de Pretis N, Pérez-Cuadrado-Robles E, Uribarri-Gonzalez L, Ateeb Z, Belfiori G, Maisonneuve P, Capurso G, Vanella G, Petrone MC, Arcidiacono PG, Vaalavuo Y, Frulloni L, Dominguez-Muñoz JE, Deprez PH, Falconi M, Del Chiaro M, Crippa S, Laukkarinen J. Identification of patients with branch-duct intraductal papillary mucinous neoplasm and very low risk of cancer: multicentre study. Br J Surg. 2022 Jun 14;109(7):617-622. PubMed PMID: 35511697
  • Valente R, Crippa S, Arnelo U, Vanella G, Zerboni G, Zarantonello L, Fogliati A, Arcidiacono PG, Vujasinovic M, Lohr JM, Falconi M, Capurso G, Del Chiaro M. The use of ace inhibitors influences the risk of progression of BD-IPMNs under follow-up. Pancreatology. 2022 May;22(4):516-524. PubMed PMID: 35431111
  • Nikolic S, Ghorbani P, Pozzi Mucelli R, Ghazi S, Baldaque-Silva F, Del Chiaro M, Sparrelid E, Verbeke CS, Löhr JM, Vujasinovic M. Surgery in Autoimmune Pancreatitis. Dig Surg. 2022;39(1):32-41. PubMed PMID: 34915509
  • Piper M, Van Court B, Mueller A, Watanabe S, Bickett T, Bhatia S, Darragh LB, Mayeda M, Nguyen D, Gadwa J, Knitz M, Corbo S, Morgan R, Lee JJ, Dent A, Goodman K, Messersmith W, Schulick R, Del Chiaro M, Zhu Y, Kedl RM, Lenz L, Karam SD. Targeting Treg-Expressed STAT3 Enhances NK-Mediated Surveillance of Metastasis and Improves Therapeutic Response in Pancreatic Adenocarcinoma. Clin Cancer Res. 2022 Mar 1;28(5):1013-1026. PubMed PMID: 34862244
  • Marchegiani G, Barreto SG, Bannone E, Sarr M, Vollmer CM, Connor S, Falconi M, Besselink MG, Salvia R, Wolfgang CL, Zyromski NJ, Yeo CJ, Adham M, Siriwardena AK, Takaori K, Hilal MA, Loos M, Probst P, Hackert T, Strobel O, Busch ORC, Lillemoe KD, Miao Y, Halloran CM, Werner J, Friess H, Izbicki JR, Bockhorn M, Vashist YK, Conlon K, Passas I, Gianotti L, Del Chiaro M, Schulick RD, Montorsi M, Oláh A, Fusai GK, Serrablo A, Zerbi A, Fingerhut A, Andersson R, Padbury R, Dervenis C, Neoptolemos JP, Bassi C, Büchler MW, Shrikhande SV. Postpancreatectomy Acute Pancreatitis (PPAP): Definition and Grading From the International Study Group for Pancreatic Surgery (ISGPS). Ann Surg. 2022 Apr 1;275(4):663-672. PubMed PMID: 34596077
  • Gaiser RA, Pessia A, Ateeb Z, Davanian H, Moro CF, Alkharaan H, Healy K, Ghazi S, Arnelo U, Valente R, Velagapudi V, Chen MS, Del Chiaro M. Author Correction: Integrated targeted metabolomic and lipidomic analysis: A novel approach to classifying early cystic precursors to invasive pancreatic cancer. Sci Rep. 2022 Mar 28;12(1):5281. PubMed PMID: 35347146
  • Oba A, Del Chiaro M, Satoi S, Kim SW, Takahashi H, Yu J, Hioki M, Tanaka M, Kato Y, Ariake K, Wu YHA, Inoue Y, Takahashi Y, Hackert T, Wolfgang CL, Besselink MG, Schulick RD, Nagakawa Y, Isaji S, Tsuchida A, Endo I. New criteria of resectability for pancreatic cancer: A position paper by the Japanese Society of Hepato-Biliary-Pancreatic Surgery (JSHBPS). J Hepatobiliary Pancreat Sci. 2022 Jul;29(7):725-731. PubMed PMID: 34581016
  • Pozzi Mucelli RM, Moro CF, Del Chiaro M, Valente R, Blomqvist L, Papanikolaou N, Löhr JM, Kartalis N. Branch-duct intraductal papillary mucinous neoplasm (IPMN): Are cyst volumetry and other novel imaging features able to improve malignancy prediction compared to well-established resection criteria?. Eur Radiol. 2022 Aug;32(8):5144-5155. PubMed PMID: 35275259
  • Oba A, Croce C, Hosokawa P, Meguid C, Torphy RJ, Al-Musawi MH, Ahrendt S, Gleisner A, Schulick RD, Del Chiaro M. Prognosis Based Definition of Resectability in Pancreatic Cancer: A Road Map to New Guidelines. Ann Surg. 2022 Jan 1;275(1):175-181. PubMed PMID: 32149822
  • Oba A, Wu YHA, Colborn KL, Karam SD, Meguid C, Al-Musawi MH, Bao QR, Gleisner AL, Ahrendt S, Schulick RD, Del Chiaro M. Comparing neoadjuvant chemotherapy with or without radiation therapy for pancreatic ductal adenocarcinoma: National Cancer Database cohort analysis. Br J Surg. 2022 Apr 19;109(5):450-454. PubMed PMID: 35136963
  • Valente R, Zarantonello L, Del Chiaro M, Vujasinovic M, Baldaque Silva F, Scandavini CM, Rangelova E, Vespasiano F, Anzillotti G, Löhr JM, Arnelo U. Lumen apposing metal stents vs double pigtail plastic stents for the drainage of pancreatic walled-off necrosis. Minerva Gastroenterol (Torino). 2022 Feb 3. [Epub ahead of print] PubMed PMID: 35112820
  • Stoop TF, Ghorbani P, Scholten L, Bergquist E, Ateeb Z, van Dieren S, Holmberg M, Besselink MG, Sparrelid E, Del Chiaro M. Total pancreatectomy as an alternative to high-risk pancreatojejunostomy after pancreatoduodenectomy: a propensity score analysis on surgical outcome and quality of life. HPB (Oxford). 2022 Aug;24(8):1261-1270. PubMed PMID: 35031280
  • Nikolic S, Ghorbani P, Pozzi Mucelli R, Ghazi S, Baldaque-Silva F, Del Chiaro M, Sparrelid E, Verbeke CS, Löhr JM, Vujasinovic M. Surgery in Autoimmune Pancreatitis. Dig Surg. 2022;39(1):32-41. PubMed PMID: 34915509
  • Piper M, Van Court B, Mueller A, Watanabe S, Bickett T, Bhatia S, Darragh LB, Mayeda M, Nguyen D, Gadwa J, Knitz M, Corbo S, Morgan R, Lee JJ, Dent A, Goodman K, Messersmith W, Schulick R, Del Chiaro M, Zhu Y, Kedl RM, Lenz L, Karam SD. Targeting Treg-Expressed STAT3 Enhances NK-Mediated Surveillance of Metastasis and Improves Therapeutic Response in Pancreatic Adenocarcinoma. Clin Cancer Res. 2022 Mar 1;28(5):1013-1026. PubMed PMID: 34862244
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  • Abu-El-Haija M, Anazawa T, Beilman GJ, Besselink MG, Del Chiaro M, Demir IE, Dennison AR, Dudeja V, Freeman ML, Friess H, Hackert T, Kleeff J, Laukkarinen J, Levy MF, Nathan JD, Werner J, Windsor JA, Neoptolemos JP, Sheel ARG, Shimosegawa T, Whitcomb DC, Bellin MD. The role of total pancreatectomy with islet autotransplantation in the treatment of chronic pancreatitis: A report from the International Consensus Guidelines in chronic pancreatitis. Pancreatology. 2020 Jun;20(4):762-771. PubMed PMID: 32327370
  • Torphy RJ, Stewart C, Sharma P, Halpern AL, Oase K, Herter W, Bartsch C, Friedman C, Del Chiaro M, Schulick RD, Gleisner A, McCarter MD, Ahrendt SA. Dextrose-Containing Carrier Solution for Hyperthermic Intraperitoneal Chemotherapy: Increased Intraoperative Hyperglycemia and Postoperative Complications. Ann Surg Oncol. 2020 Dec;27(13):4874-4882. PubMed PMID: 32306237
  • Miao Y, Lu Z, Yeo CJ, Vollmer CM Jr, Fernandez-Del Castillo C, Ghaneh P, Halloran CM, Kleeff J, de Rooij T, Werner J, Falconi M, Friess H, Zeh HJ, Izbicki JR, He J, Laukkarinen J, Dejong CH, Lillemoe KD, Conlon K, Takaori K, Gianotti L, Besselink MG, Del Chiaro M, Montorsi M, Tanaka M, Bockhorn M, Adham M, Oláh A, Salvia R, Shrikhande SV, Hackert T, Shimosegawa T, Zureikat AH, Ceyhan GO, Peng Y, Wang G, Huang X, Dervenis C, Bassi C, Neoptolemos JP, Büchler MW. Management of the pancreatic transection plane after left (distal) pancreatectomy: Expert consensus guidelines by the International Study Group of Pancreatic Surgery (ISGPS). Surgery. 2020 Jul;168(1):72-84. PubMed PMID: 32249092
  • Valente R, Waldthaler A, Scandavini CM, Vujasinovic M, Del Chiaro M, Arnelo U, Löhr JM. Conservative Treatment of Chronic Pancreatitis: A Practical Approach. Scand J Surg. 2020 Mar;109(1):59-68. PubMed PMID: 32192418
  • Oba A, Ho F, Bao QR, Al-Musawi MH, Schulick RD, Del Chiaro M. Neoadjuvant Treatment in Pancreatic Cancer. Front Oncol. 2020;10:245. PubMed PMID: 32185128
  • Siriwardena AK, Windsor J, Zyromski N, Marchegiani G, Radenkovic D, Morgan C, Passas I, Olah A, Conlon KC, Smith M, Busch O, Baltatzis M, Besselink MG, Vollmer C, Castillo CF, Friess H, Garcea G, Burmeister S, Hackert T, Lillemoe KD, Schulick R, Shrikhande SV, Smith A, Gianotti L, Falconi M, Adams D, Adham M, Andersson R, Del Chiaro M, Devar J, Jegatheeswaran S, van Santvoort H, Khatkov I, Izbicki J, Büchler M, Neoptolemos JP, Bassi C, Dervenis C. Standards for reporting on surgery for chronic pancreatitis: a report from the International Study Group for Pancreatic Surgery (ISGPS). Surgery. 2020 Jul;168(1):101-105. PubMed PMID: 32183994
  • Oba A, Croce C, Hosokawa P, Meguid C, Torphy RJ, Al-Musawi MH, Ahrendt S, Gleisner A, Schulick RD, Del Chiaro M. Prognosis Based Definition of Resectability in Pancreatic Cancer: A Road Map to New Guidelines. Ann Surg. 2020 Mar 6. [Epub ahead of print] PubMed PMID: 32149822
  • Reuterwall M, Waldthaler A, Lubbe J, Kadesjö N, Pozzi Mucelli R, Del Chiaro M, Lohr M, Arnelo U. Bimodal ERCP, a new way of seeing things. Endosc Int Open. 2020 Mar;8(3):E368-E376. PubMed PMID: 32118109
  • Oba A, Bao QR, Barnett CC, Al-Musawi MH, Croce C, Schulick RD, Del Chiaro M. Vascular Resections for Pancreatic Ductal Adenocarcinoma: Vascular Resections for PDAC. Scand J Surg. 2020 Mar;109(1):18-28. PubMed PMID: 31960765
  • van Roessel S, Strijker M, Steyerberg EW, Groen JV, Mieog JS, Groot VP, He J, De Pastena M, Marchegiani G, Bassi C, Suhool A, Jang JY, Busch OR, Halimi A, Zarantonello L, Groot Koerkamp B, Samra JS, Mittal A, Gill AJ, Bolm L, van Eijck CH, Abu Hilal M, Del Chiaro M, Keck T, Alseidi A, Wolfgang CL, Malleo G, Besselink MG. International validation and update of the Amsterdam model for prediction of survival after pancreatoduodenectomy for pancreatic cancer. Eur J Surg Oncol. 2020 May;46(5):796-803. PubMed PMID: 31924432
  • Goggins M, Overbeek KA, Brand R, Syngal S, Del Chiaro M, Bartsch DK, Bassi C, Carrato A, Farrell J, Fishman EK, Fockens P, Gress TM, van Hooft JE, Hruban RH, Kastrinos F, Klein A, Lennon AM, Lucas A, Park W, Rustgi A, Simeone D, Stoffel E, Vasen HFA, Cahen DL, Canto MI, Bruno M. Management of patients with increased risk for familial pancreatic cancer: updated recommendations from the International Cancer of the Pancreas Screening (CAPS) Consortium. Gut. 2020 Jan;69(1):7-17. PubMed PMID: 31672839
  • Stoop TF, Del Chiaro M. ASO Author Reflections: Acceptable Impact of Endocrine and Exocrine Insufficiency on Quality of Life After Total Pancreatectomy. Ann Surg Oncol. 2020 Feb;27(2):597-598. PubMed PMID: 31654166
  • Asbun HJ, Moekotte AL, Vissers FL, Kunzler F, Cipriani F, Alseidi A, D'Angelica MI, Balduzzi A, Bassi C, Björnsson B, Boggi U, Callery MP, Del Chiaro M, Coimbra FJ, Conrad C, Cook A, Coppola A, Dervenis C, Dokmak S, Edil BH, Edwin B, Giulianotti PC, Han HS, Hansen PD, van der Heijde N, van Hilst J, Hester CA, Hogg ME, Jarufe N, Jeyarajah DR, Keck T, Kim SC, Khatkov IE, Kokudo N, Kooby DA, Korrel M, de Leon FJ, Lluis N, Lof S, Machado MA, Demartines N, Martinie JB, Merchant NB, Molenaar IQ, Moravek C, Mou YP, Nakamura M, Nealon WH, Palanivelu C, Pessaux P, Pitt HA, Polanco PM, Primrose JN, Rawashdeh A, Sanford DE, Senthilnathan P, Shrikhande SV, Stauffer JA, Takaori K, Talamonti MS, Tang CN, Vollmer CM, Wakabayashi G, Walsh RM, Wang SE, Zinner MJ, Wolfgang CL, Zureikat AH, Zwart MJ, Conlon KC, Kendrick ML, Zeh HJ, Hilal MA, Besselink MG. The Miami International Evidence-based Guidelines on Minimally Invasive Pancreas Resection. Ann Surg. 2020 Jan;271(1):1-14. PubMed PMID: 31567509
  • Stoop TF, Ateeb Z, Ghorbani P, Scholten L, Arnelo U, Besselink MG, Del Chiaro M. Impact of Endocrine and Exocrine Insufficiency on Quality of Life After Total Pancreatectomy. Ann Surg Oncol. 2020 Feb;27(2):587-596. PubMed PMID: 31562603
  • Del Chiaro M, Beckman R, Ateeb Z, Orsini N, Rezaee N, Manos L, Valente R, Yuan C, Ding D, Margonis GA, Yin L, Cameron JL, Makary MA, Burkhart RA, Weiss MJ, He J, Arnelo U, Yu J, Wolfgang CL. Main Duct Dilatation Is the Best Predictor of High-grade Dysplasia or Invasion in Intraductal Papillary Mucinous Neoplasms of the Pancreas. Ann Surg. 2020 Dec;272(6):1118-1124. PubMed PMID: 30672797
  • Rangelova E, Orsini N, Del Chiaro M. Response to Comment on "Surgery Improves Survival After Neoadjuvant Therapy for Borderline and Locally Advanced Pancreatic Cancer". Ann Surg. 2019 Dec;270(6):e139-e141. PubMed PMID: 31730557
  • Del Chiaro M, Valente R, Wolfgang C. Response to Comment on "Main Duct Dilatation is the Best Predictor of High-grade Dysplasia or Invasion in Intraductal Papillary Mucinous Neoplasms of the Pancreas". Ann Surg. 2019 Dec;270(6):e109-e110. PubMed PMID: 31726634
  • Stoop TF, Del Chiaro M. ASO Author Reflections: Acceptable Impact of Endocrine and Exocrine Insufficiency on Quality of Life After Total Pancreatectomy. Ann Surg Oncol. 2019 Oct 25. [Epub ahead of print] PubMed PMID: 31654166
  • Stoop TF, Ateeb Z, Ghorbani P, Scholten L, Arnelo U, Besselink MG, Del Chiaro M. Impact of Endocrine and Exocrine Insufficiency on Quality of Life After Total Pancreatectomy. Ann Surg Oncol. 2019 Sep 27. [Epub ahead of print] PubMed PMID: 31562603
  • Held T, Verbeke CS, Strobel O, Rutkowski W, Villard C, Moro CF, Del Chiaro M, Büchler M, Heuchel R, Löhr M. Immunohistochemical profiling of liver metastases and matched-pair analysis in patients with metastatic pancreatic ductal adenocarcinoma. Pancreatology. 2019 Oct;19(7):963-970. PubMed PMID: 31542399
  • van Huijgevoort NCM, Del Chiaro M, Wolfgang CL, van Hooft JE, Besselink MG. Diagnosis and management of pancreatic cystic neoplasms: current evidence and guidelines. Nat Rev Gastroenterol Hepatol. 2019 Nov;16(11):676-689. PubMed PMID: 31527862
  • Moore HB, Culp-Hill R, Reisz JA, Lawson PJ, Sauaia A, Schulick RD, Del Chiaro M, Nydam TL, Moore EE, Hansen KC, D'Alessandro A. The metabolic time line of pancreatic cancer: Opportunities to improve early detection of adenocarcinoma. Am J Surg. 2019 Dec;218(6):1206-1212. PubMed PMID: 31514959
  • Scholten L, Stoop TF, Del Chiaro M, Busch OR, van Eijck C, Molenaar IQ, de Vries JH, Besselink MG. Systematic review of functional outcome and quality of life after total pancreatectomy. Br J Surg. 2019 Dec;106(13):1735-1746. PubMed PMID: 31502658
  • Jung W, Park T, Kim Y, Park H, Han Y, He J, Wolfgang CL, Blair A, Rashid MF, Kluger MD, Su GH, Chabot JA, Yang CY, Lou W, Valente R, Del Chiaro M, Shyr YM, Wang SE, van Huijgevoort NCM, Besselink MG, Yang Y, Kim H, Kwon W, Kim SW, Jang JY. Validation of a nomogram to predict the risk of cancer in patients with intraductal papillary mucinous neoplasm and main duct dilatation of 10?mm or less. Br J Surg. 2019 Dec;106(13):1829-1836. PubMed PMID: 31441048
  • van Veldhuisen E, van den Oord C, Brada LJ, Walma MS, Vogel JA, Wilmink JW, Del Chiaro M, van Lienden KP, Meijerink MR, van Tienhoven G, Hackert T, Wolfgang CL, van Santvoort H, Groot Koerkamp B, Busch OR, Molenaar IQ, van Eijck CH, Besselink MG. Locally Advanced Pancreatic Cancer: Work-Up, Staging, and Local Intervention Strategies. Cancers (Basel). 2019 Jul 12;11(7). PubMed PMID: 31336859
  • Del Chiaro M, Arnelo U, Rangelova E, Valente R, Verbeke C. RE: Pancreatectomy with arterial resection. HPB (Oxford). 2019 Sep;21(9):1254-1255. PubMed PMID: 31320240
  • Gaiser RA, Pessia A, Ateeb Z, Davanian H, Fernández Moro C, Alkharaan H, Healy K, Ghazi S, Arnelo U, Valente R, Velagapudi V, Sällberg Chen M, Del Chiaro M. Integrated targeted metabolomic and lipidomic analysis: A novel approach to classifying early cystic precursors to invasive pancreatic cancer. Sci Rep. 2019 Jul 15;9(1):10208. PubMed PMID: 31308419
  • Del Chiaro M, Schulick RD. It is time for a biological definition of locally advanced pancreatic cancer. Br J Surg. 2019 Aug;106(9):1257. PubMed PMID: 31304574
  • Sakaguchi T, Valente R, Tanaka K, Satoi S, Del Chiaro M. Surgical treatment of metastatic pancreatic ductal adenocarcinoma: A review of current literature. Pancreatology. 2019 Jul;19(5):672-680. PubMed PMID: 31285145
  • Torphy RJ, Chapman BC, Friedman C, Nguyen C, Bartsch CG, Meguid C, Ahrendt SA, McCarter MD, Del Chiaro M, Schulick RD, Edil BH, Gleisner A. Quality of Life Following Major Laparoscopic or Open Pancreatic Resection. Ann Surg Oncol. 2019 Sep;26(9):2985-2993. PubMed PMID: 31228131
  • Arnelo U, Rangelova E, Del Chiaro M, Valente R, Verbeke C. RE: correct reporting is of utmost importance when a controversial treatment is being evaluated. HPB (Oxford). 2019 Sep;21(9):1251-1252. PubMed PMID: 31109873
  • Rangelova E, Wefer A, Persson S, Valente R, Tanaka K, Orsini N, Segersvärd R, Arnelo U, Del Chiaro M. Surgery Improves Survival After Neoadjuvant Therapy for Borderline and Locally Advanced Pancreatic Cancer: A Single Institution Experience. Ann Surg. 2019 Apr 2. [Epub ahead of print] PubMed PMID: 30946073
  • Gaiser RA, Halimi A, Alkharaan H, Lu L, Davanian H, Healy K, Hugerth LW, Ateeb Z, Valente R, Fernández Moro C, Del Chiaro M, Sällberg Chen M. Enrichment of oral microbiota in early cystic precursors to invasive pancreatic cancer. Gut. 2019 Dec;68(12):2186-2194. PubMed PMID: 30872392
  • Sánchez-Velázquez P, Muller X, Malleo G, Park JS, Hwang HK, Napoli N, Javed AA, Inoue Y, Beghdadi N, Kalisvaart M, Vigia E, Walsh CD, Lovasik B, Busquets J, Scandavini C, Robin F, Yoshitomi H, Mackay TM, Busch OR, Hartog H, Heinrich S, Gleisner A, Perinel J, Passeri M, Lluis N, Raptis DA, Tschuor C, Oberkofler CE, DeOliveira ML, Petrowsky H, Martinie J, Asbun H, Adham M, Schulick R, Lang H, Koerkamp BG, Besselink MG, Han HS, Miyazaki M, Ferrone CR, Fernández-Del Castillo C, Lillemoe KD, Sulpice L, Boudjema K, Del Chiaro M, Fabregat J, Kooby DA, Allen P, Lavu H, Yeo CJ, Barroso E, Roberts K, Muiesan P, Sauvanet A, Saiura A, Wolfgang CL, Cameron JL, Boggi U, Yoon DS, Bassi C, Puhan MA, Clavien PA. Benchmarks in Pancreatic Surgery: A Novel Tool for Unbiased Outcome Comparisons. Ann Surg. 2019 Aug;270(2):211-218. PubMed PMID: 30829701
  • Reuterwall M, Lubbe J, Enochsson L, Lundell L, Konradsson M, Swahn F, Del Chiaro M, Löhr M, Arnelo U. The clinical value of ERCP-guided cholangiopancreatoscopy using a single-operator system. BMC Gastroenterol. 2019 Feb 26;19(1):35. PubMed PMID: 30808288
  • Misra S, Moro CF, Del Chiaro M, Pouso S, Sebestyén A, Löhr M, Björnstedt M, Verbeke CS. Ex vivo organotypic culture system of precision-cut slices of human pancreatic ductal adenocarcinoma. Sci Rep. 2019 Feb 14;9(1):2133. PubMed PMID: 30765891
  • Del Chiaro M, Beckman R, Ateeb Z, Orsini N, Rezaee N, Manos L, Valente R, Yuan C, Ding D, Margonis GA, Yin L, Cameron JL, Makary MA, Burkhart RA, Weiss MJ, He J, Arnelo U, Yu J, Wolfgang CL. Main Duct Dilatation Is the Best Predictor of High-grade Dysplasia or Invasion in Intraductal Papillary Mucinous Neoplasms of the Pancreas. Ann Surg. 2019 Jan 18. [Epub ahead of print] PubMed PMID: 30672797
  • Ateeb Z, Valente R, Pozzi-Mucelli RM, Malgerud L, Schlieper Y, Rangelova E, Fernandez-Moro C, Löhr JM, Arnelo U, Del Chiaro M. Main pancreatic duct dilation greater than 6 mm is associated with an increased risk of high-grade dysplasia and cancer in IPMN patients. Langenbecks Arch Surg. 2019 Feb;404(1):31-37. PubMed PMID: 30612152
  • Del Chiaro M, Schulick RD. Use of Total Pancreatectomy and Preoperative Radiotherapy in Patients Undergoing Pancreatectomy with Artery Resection. J Am Coll Surg. 2019 Jan;228(1):131. PubMed PMID: 30580801
  • Meng Q, Valentini D, Rao M, Moro CF, Paraschoudi G, Jäger E, Dodoo E, Rangelova E, Del Chiaro M, Maeurer M. Neoepitope targets of tumour-infiltrating lymphocytes from patients with pancreatic cancer. Br J Cancer. 2019 Jan;120(1):97-108. PubMed PMID: 30377343
  • Del Chiaro M, Rangelova E, Halimi A, Ateeb Z, Scandavini C, Valente R, Segersvärd R, Arnelo U, Verbeke CS. Pancreatectomy with arterial resection is superior to palliation in patients with borderline resectable or locally advanced pancreatic cancer. HPB (Oxford). 2019 Feb;21(2):219-225. PubMed PMID: 30093144
  • van Hilst J, de Rooij T, Klompmaker S, Rawashdeh M, Aleotti F, Al-Sarireh B, Alseidi A, Ateeb Z, Balzano G, Berrevoet F, Björnsson B, Boggi U, Busch OR, Butturini G, Casadei R, Del Chiaro M, Chikhladze S, Cipriani F, van Dam R, Damoli I, van Dieren S, Dokmak S, Edwin B, van Eijck C, Fabre JM, Falconi M, Farges O, Fernández-Cruz L, Forgione A, Frigerio I, Fuks D, Gavazzi F, Gayet B, Giardino A, Groot Koerkamp B, Hackert T, Hassenpflug M, Kabir I, Keck T, Khatkov I, Kusar M, Lombardo C, Marchegiani G, Marshall R, Menon KV, Montorsi M, Orville M, de Pastena M, Pietrabissa A, Poves I, Primrose J, Pugliese R, Ricci C, Roberts K, Røsok B, Sahakyan MA, Sánchez-Cabús S, Sandström P, Scovel L, Solaini L, Soonawalla Z, Souche FR, Sutcliffe RP, Tiberio GA, Tomazic A, Troisi R, Wellner U, White S, Wittel UA, Zerbi A, Bassi C, Besselink MG, Abu Hilal M. Minimally Invasive versus Open Distal Pancreatectomy for Ductal Adenocarcinoma (DIPLOMA): A Pan-European Propensity Score Matched Study. Ann Surg. 2019 Jan;269(1):10-17. PubMed PMID: 29099399
  • Meng Q, Valentini D, Rao M, Moro CF, Paraschoudi G, Jäger E, Dodoo E, Rangelova E, Del Chiaro M, Maeurer M. Neoepitope targets of tumour-infiltrating lymphocytes from patients with pancreatic cancer. Br J Cancer. 2018 Oct 31. [Epub ahead of print] PubMed PMID: 30377343
  • Vujasinovic M, Valente R, Maier P, von Beckerath V, Haas SL, Arnelo U, Del Chiaro M, Kartalis N, Pozzi-Mucelli RM, Fernandez-Moro C, Verbeke CS, Yu J, Ye W, Löhr JM. Diagnosis, treatment and long-term outcome of autoimmune pancreatitis in Sweden. Pancreatology. 2018 Dec;18(8):900-904. PubMed PMID: 30236651
  • Del Chiaro M, Søreide K. Trials and tribulations of neoadjuvant therapy in pancreatic cancer. Br J Surg. 2018 Oct;105(11):1387-1389. PubMed PMID: 30221767
  • Scholten L, van Huijgevoort NCM, van Hooft JE, Besselink MG, Del Chiaro M. Pancreatic Cystic Neoplasms: Different Types, Different Management, New Guidelines. Visc Med. 2018 Jul;34(3):173-177. PubMed PMID: 30182024
  • Loizou L, Duran CV, Axelsson E, Andersson M, Keussen I, Strinnholm J, Bartholomä W, Del Chiaro M, Segersvärd R, Lundell L, Kartalis N. Radiological assessment of local resectability status in patients with pancreatic cancer: Interreader agreement and reader performance in two different classification systems. Eur J Radiol. 2018 Sep;106:69-76. PubMed PMID: 30150053
  • Del Chiaro M, Rangelova E, Halimi A, Ateeb Z, Scandavini C, Valente R, Segersvärd R, Arnelo U, Verbeke CS. Pancreatectomy with arterial resection is superior to palliation in patients with borderline resectable or locally advanced pancreatic cancer. HPB (Oxford). 2018 Aug 6. [Epub ahead of print] PubMed PMID: 30093144
  • Gianotti L, Besselink MG, Sandini M, Hackert T, Conlon K, Gerritsen A, Griffin O, Fingerhut A, Probst P, Abu Hilal M, Marchegiani G, Nappo G, Zerbi A, Amodio A, Perinel J, Adham M, Raimondo M, Asbun HJ, Sato A, Takaori K, Shrikhande SV, Del Chiaro M, Bockhorn M, Izbicki JR, Dervenis C, Charnley RM, Martignoni ME, Friess H, de Pretis N, Radenkovic D, Montorsi M, Sarr MG, Vollmer CM, Frulloni L, Büchler MW, Bassi C. Nutritional support and therapy in pancreatic surgery: A position paper of the International Study Group on Pancreatic Surgery (ISGPS). Surgery. 2018 Nov;164(5):1035-1048. PubMed PMID: 30029989
  • Meng Q, Valentini D, Rao M, Liu Z, Xie S, Morgell A, Dodoo E, Löhr M, Rangelova E, Del Chiaro M, Ernberg I, Maeurer M. Prediction of improved survival in patients with pancreatic cancer via IL-21 enhanced detection of mesothelin epitope-reactive T-cell responses. Oncotarget. 2018 Apr 27;9(32):22451-22459. PubMed PMID: 29854291
  • Scholten L, van Huijgevoort NCM, Bruno MJ, Fernandez-Del Castillo C, Satoi S, Sauvanet A, Wolfgang C, Fockens P, Chari ST, Del Chiaro M, van Hooft JE, Besselink MG. Surgical management of intraductal papillary mucinous neoplasm with main duct involvement: an international expert survey and case-vignette study. Surgery. 2018 May 16. [Epub ahead of print] PubMed PMID: 29778250
  • Klompmaker S, van Hilst J, Gerritsen SL, Adham M, Teresa Albiol Quer M, Bassi C, Berrevoet F, Boggi U, Busch OR, Cesaretti M, Dalla Valle R, Darnis B, De Pastena M, Del Chiaro M, Grützmann R, Diener MK, Dumitrascu T, Friess H, Ivanecz A, Karayiannakis A, Fusai GK, Labori KJ, Lombardo C, López-Ben S, Mabrut JY, Niesen W, Pardo F, Perinel J, Popescu I, Roeyen G, Sauvanet A, Prasad R, Sturesson C, Lesurtel M, Kleeff J, Salvia R, Besselink MG. Correction to: Outcomes After Distal Pancreatectomy with Celiac Axis Resection for Pancreatic Cancer: A Pan-European Retrospective Cohort Study. Ann Surg Oncol. 2018 Mar 20. [Epub ahead of print] PubMed PMID: 29560574
  • Klompmaker S, van Hilst J, Gerritsen SL, Adham M, Teresa Albiol Quer M, Bassi C, Berrevoet F, Boggi U, Busch OR, Cesaretti M, Dalla Valle R, Darnis B, De Pastena M, Del Chiaro M, Grützmann R, Diener MK, Dumitrascu T, Friess H, Ivanecz A, Karayiannakis A, Fusai GK, Labori KJ, Lombardo C, López-Ben S, Mabrut JY, Niesen W, Pardo F, Perinel J, Popescu I, Roeyen G, Sauvanet A, Prasad R, Sturesson C, Lesurtel M, Kleeff J, Salvia R, Besselink MG. Outcomes After Distal Pancreatectomy with Celiac Axis Resection for Pancreatic Cancer: A Pan-European Retrospective Cohort Study. Ann Surg Oncol. 2018 May;25(5):1440-1447. PubMed PMID: 29532342
  • Keane MG, Shamali A, Nilsson LN, Antila A, Millastre Bocos J, Marijinissen Van Zanten M, Verdejo Gil C, Maisonneuve P, Vaalavuo Y, Hoskins T, Robinson S, Ceyhan GO, Abu Hilal M, Pereira SP, Laukkarinen J, Del Chiaro M. Risk of malignancy in resected pancreatic mucinous cystic neoplasms. Br J Surg. 2018 Mar;105(4):439-446. PubMed PMID: 29488646
  • Scandavini C, Valente R, Rangelova E, Segersvärd R, Arnelo U, Permert J, Svensson PJ, Stenman J, Del Chiaro M. Pancreatectomies for pancreatic neoplasms in pediatric and adolescent age: A single institution experience. Pancreatology. 2018 Mar;18(2):204-207. PubMed PMID: 29277262
  • Morelli L, Di Franco G, Guadagni S, Palmeri M, Furbetta N, Gianardi D, Del Chiaro M, Di Candio G, Mosca F. Technical Details and Results of a Modified End-to-Side Technique of Pancreatojejunostomy: a Personal Series of 100 Patients. J Gastrointest Surg. 2017 Dec;21(12):2090-2099. PubMed PMID: 28936588
  • Olsson G, Frozanpor F, Lundell L, Enochsson L, Ansorge C, Del Chiaro M, Reuterwall-Hansson M, Shetye A, Arnelo U. Preoperative biliary drainage by plastic or self-expandable metal stents in patients with periampullary tumors: results of a randomized clinical study. Endosc Int Open. 2017 Sep;5(9):E798-E808. PubMed PMID: 28879225
  • Del Chiaro M, Valente R, Arnelo U. Neoadjuvant Treatment in Locally Advanced and Borderline Resectable Pancreatic Cancer vs Primary Resectable Pancreatic Cancer. JAMA Surg. 2017 Nov 1;152(11):1057. PubMed PMID: 28700786
  • Malgerud L, Lindberg J, Wirta V, Gustafsson-Liljefors M, Karimi M, Moro CF, Stecker K, Picker A, Huelsewig C, Stein M, Bohnert R, Del Chiaro M, Haas SL, Heuchel RL, Permert J, Maeurer MJ, Brock S, Verbeke CS, Engstrand L, Jackson DB, Grönberg H, Löhr JM. Bioinformatory-assisted analysis of next-generation sequencing data for precision medicine in pancreatic cancer. Mol Oncol. 2017 Oct;11(10):1413-1429. PubMed PMID: 28675654
  • Del Chiaro M, Arnelo U, Valente R. Pancreatic Cystic Neoplasms: To Needle or Not To Needle, This Is the Question. Am J Gastroenterol. 2017 May;112(5):804. PubMed PMID: 28469233
  • Vujasinovic M, Valente R, Del Chiaro M, Permert J, Löhr JM. Pancreatic Exocrine Insufficiency in Pancreatic Cancer. Nutrients. 2017 Feb 23;9(3). PubMed PMID: 28241470
  • Rangelova E, Valente R, Del Chiaro M. "Step-Up Approach" for the Treatment of Postoperative Severe Pancreatic Fistula: Is It Really Possible and Useful?. JAMA Surg. 2017 Jun 1;152(6):548-549. PubMed PMID: 28241218
  • Fernández Moro C, Fernandez-Woodbridge A, Alistair D'souza M, Zhang Q, Bozoky B, Vasan SK, Catalano P, Heuchel R, Shtembari S, Del Chiaro M, Danielsson O, Björnstedt M, Löhr JM, Isaksson B, Verbeke C, Bozóky B. Correction: Immunohistochemical Typing of Adenocarcinomas of the Pancreatobiliary System Improves Diagnosis and Prognostic Stratification. PLoS One. 2017;12(1):e0171283. PubMed PMID: 28125728
  • Bassi C, Marchegiani G, Dervenis C, Sarr M, Abu Hilal M, Adham M, Allen P, Andersson R, Asbun HJ, Besselink MG, Conlon K, Del Chiaro M, Falconi M, Fernandez-Cruz L, Fernandez-Del Castillo C, Fingerhut A, Friess H, Gouma DJ, Hackert T, Izbicki J, Lillemoe KD, Neoptolemos JP, Olah A, Schulick R, Shrikhande SV, Takada T, Takaori K, Traverso W, Vollmer CR, Wolfgang CL, Yeo CJ, Salvia R, Buchler M. The 2016 update of the International Study Group (ISGPS) definition and grading of postoperative pancreatic fistula: 11 Years After. Surgery. 2017 Mar;161(3):584-591. PubMed PMID: 28040257
  • Del Chiaro M, Valente R, Arnelo U. Minimally Invasive Pancreaticoduodenectomy for the Treatment of Pancreatic-Head and Periampullary Tumors. JAMA Surg. 2017 Apr 1;152(4):343. PubMed PMID: 28030664
  • Del Chiaro M, Verbeke C. Intraductal papillary mucinous neoplasms of the pancreas: reporting clinically relevant features. Histopathology. 2017 May;70(6):850-860. PubMed PMID: 27878841
  • Del Chiaro M, Ateeb Z, Hansson MR, Rangelova E, Segersvärd R, Kartalis N, Ansorge C, Löhr MJ, Arnelo U, Verbeke C. Survival Analysis and Risk for Progression of Intraductal Papillary Mucinous Neoplasia of the Pancreas (IPMN) Under Surveillance: A Single-Institution Experience. Ann Surg Oncol. 2017 Apr;24(4):1120-1126. PubMed PMID: 27822633
  • Pozzi-Mucelli RM, Rinta-Kiikka I, Wünsche K, Laukkarinen J, Labori KJ, Ånonsen K, Verbeke C, Del Chiaro M, Kartalis N. Pancreatic MRI for the surveillance of cystic neoplasms: comparison of a short with a comprehensive imaging protocol. Eur Radiol. 2017 Jan;27(1):41-50. PubMed PMID: 27246720
  • Del Chiaro M, Schulick RD. Main-duct Intraductal Papillary Mucinous Neoplasm. High Cancer Risk in Duct Diameter of 5 to 9 mm. Ann Surg. 2017 Dec;266(6):e86. PubMed PMID: 27043742
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Practice Locations

UCHealth University of Colorado Hospital (UCH)
12605 E. 16th Ave
Aurora, CO 80045
720-848-0000

University of Colorado Cancer Center - Anschutz Medical Campus
1665 Aurora Ct
Aurora, CO 80045
720-848-0300

Pancreas & Biliary Multidisciplinary Clinic - Anschutz
1665 Aurora Ct
3rd Floor
Aurora, CO 80045
1-855-824-7262

Hospital Affiliation
  • University of Colorado Hospital
  • Children's Hospital Colorado
  • Veterans Affairs Medical Center
Center Affiliations

Specialty Information

Specialties
  • Complex General Surgical Oncology, Board Certification
  • Surgery, Board Certification
Conditions & Treatments
  • Cancers - Biliary Cancer
  • Cancers
  • Cancers - Pancreatic Cancer
  • Digestive System - Pancreas Surgery
  • Digestive System
  • Digestive System - Biliary Surgery
  • Surgery
  • Surgery - Pancreas Transplant Surgery
  • Cancers - Cancer Prevention
  • Cancers - Cancer Surgery
  • Cancers - Gastroenterologic Cancer (Colon, Stomach, Esophageal, Liver)
  • Digestive System - Gastrointestinal Surgery
Clinical Interests
Pancreas, Bile duct, Liver, Stomach, Adrenal, Sarcoma, and Cancer Surgery

Care Philosophy
Dr. Marco Del Chiaro is a surgical oncologist with 15 years of experience in the treatment of pancreatic diseases. He is internationally recognized as a leader in the surgical treatment of borderline resectable\locally advanced pancreatic cancer, as well as in the diagnosis and treatment of pancreas lesions. Dr. Del Chiaro's unique approach, combined with multimodal chemoradiotherapy, allows more surgical options for locally advanced pancreatic cancer patients. He is active in academic research, with more than 130 peer reviewed papers, and is a member of several scientific journals’ editorial boards. Dr. Del Chiaro's mission is to improve pancreatic cancer survival through both prevention and aggressive treatment of the advanced tumors and to create a multimodal personalized treatment for each patient.

General Information

Medical Schools:
  • MD, University of Pisa, Italy (1997)
Languages: English, Italian, Swedish, French
Department: Surgery-Surgical Oncology
Contact Us
CU Anschutz
Fitzsimons Building

13001 East 17th Place
Campus Box C290
Aurora, CO 80045

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