Publications:
Raghu G, Flaherty KR, Lederer DJ, Lynch DA, Colby TA, Myers JL, Larsen BT, Chung JH, Steele MP, et al. Use of a molecular classifier to identify usual interstitial pneumonia in conventional transbronchial biopsy samples: a prospective validation study. The Lancet. Respiratory Medicine. In press: April 01, 2019 https://doi.org/10.1016/S2213-2600(19)30059-1.
Moore C, Blumhagen RZ,Yang IV,Walts A, Powers J,Walker T,Bishop M, Russell P, Vestal B, Cardwell J, Markin CT,Matha SK,Schwarz MI, Steele MP, et al. Resequencing Study Confirms Host Defense and Cell Senescence Gene Variants Contribute to the Risk of Idiopathic Pulmonary Fibrosis. Am J Resp Crit Care Med. 200:199-208, 2019. PM ID 31034279.
Mathai SK, Humphries S, Kropski JA, Blackwell TS, Powers J, Walts AD, Markin C, Woodard J, Chung JH, Brown KK, Steele MP, Loyd JE, Schwarz MI, Fingerlin T, Yang IV, Lynch DA, Schwartz DA. MUC5B variant is associated with visually and quantitatively detected preclinical pulmonary fibrosis. Thorax. 74:1131-1139, 2019. PMID 31558622. http://dx.doi.org/10.1136/thoraxjnl-2018-212430
TITLE: Among Individuals At-Risk, Pre-Clinical Pulmonary Fibrosis Occurs Commonly and is Progressive.
AUTHORS: Mark P. Steele, MD1‡, Susan K. Mathai, MD2‡, Jonathan A. Kropski, MD4, Timothy S. Blackwell, MD4, Rachel Bochantin1, Julia Powers, MPH1, Avram D. Walts1, Cheryl Markin4, Kevin K. Brown, MD7, James E. Loyd, MD4, Marvin I. Schwarz, MD1, Joyce S. Lee1, David A. Lynch, MD3, Tasha E. Fingerlin, PhD6, Ivana V. Yang, MD1, David A. Schwartz, MD1*
53. Steele MP, Peljto AP,, Mathai SK, Humphries S, Bang TJ, Oh A, Teague S, Giuseppe C, Sigakis C, Kropski JA, Loyd JE, Blackwell TS, Brown KK, Schwarz, MI, Warren RA, Powers J, Walts AD, Markin C, Fingerlin TE, Yang IV, Lynch DA, Lee JS, Schwartz, DA. Incidence and Progression of Fibrotic Lung Disease in an At-Risk Cohort. Am J Resp Crit Care Med: 2022 PMID: 36094461
54. Peljto, AP, Blumhagen RZ, …Steele MP, Lee JS, Yang IV, Fingerlin TE ,Schwartz, DA and NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium. Idiopathic Pulmonary Fibrosis is Associated with Common Genetic Variants and Limited Rare Variants Am J Resp Crit Care Med 2022. PMID: 36602845
Steele MP, Peljto AP, Mathai SK, Humphries S, Bang TJ, Oh A, Teague S, Giuseppe C, Sigakis C, Kropski JA, Loyd JE, Blackwell TS, Brown KK, Schwarz, MI, Warren RA, Powers J, Walts AD, Markin C, Fingerlin TE, Yang IV, Lynch DA, Lee JS, Schwartz, DA. Incidence and Progression of Fibrotic Lung Disease in an At-Risk Cohort. Am J Resp Crit Care Med: 207:587-593, 2023 PMID: 36094461.
MUC5B polymorphism is associated with usual interstitial pneumonia pathologically and less lung injury
Jian Jing1, Carlyne Cool1-3, Steve D. Groshong2,3, Joyce S. Lee2, Gregory P. Cosgrove2,3, Jonathan Cardwell2, Janet L. Talbert4**, Cheryl R. Markin5, Raven N. Kidd6*, Max A. Seibold3, Elissa Murphy7**, Tasha E. Fingerlin8,9, James E. Loyd5, Kevin K. Brown2,3, Marvin I. Schwarz2, Ivana V. Yang2,10, Mark P. Steele3, David A. Schwartz2,3,10, Anna L. Peljto2. AJRCCM (in Press)