Sunad Rangarajan, MD

Professional Titles

• Associate Professor

Recognitions

• ACCM Teaching Award, Anesthesia Critical Care Fellowship Program, CU Anschutz (2023)
• Giles F. Filley Memorial Award for Excellence in Respiratory Physiology and Medicine, American Physiological Society (2019)
• ASCI Young Physician-Scientist Award, American Society for Clinical Investigation (2019)
• Walter B. Frommeyer Fellowship in Investigative Medicine, University of Alabama Department of Medicine (2016)

Research Interests

Cellular metabolism, mitochondrial biology and dysfunction in lung pathology; Aging

Publications

• Turner E, Roda G, Londono P, Herrera JA, Evans CM, Rangarajan S. Inhibition of Distal Glycolytic Enzymes Suppresses Fibroblast Activation without Deleterious Bioenergetic Effects. Am J Respir Cell Mol Biol. 2024 Jun;70(6):519-521. PubMed PMID: 38819122
• Rangarajan S. ANT1 and the SASP: Beyond the Bioenergetic Void. Am J Respir Cell Mol Biol. 2023 Nov;69(5):495-496. PubMed PMID: 37579125
• Rangarajan S. ANT1 and the SASP: Beyond the Bioenergetic Void. Am J Respir Cell Mol Biol. 2023 Nov;69(5):495-496. PubMed PMID: 37579125
• Rangarajan S, Locy ML, Chanda D, Kurundkar A, Kurundkar D, Larson-Casey JL, Londono P, Bagchi RA, Deskin B, Elajaili H, Nozik ES, Deshane JS, Zmijewski JW, Eickelberg O, Thannickal VJ. Mitochondrial uncoupling protein-2 reprograms metabolism to induce oxidative stress and myofibroblast senescence in age-associated lung fibrosis. Aging Cell. 2022 Sep;21(9):e13674. PubMed PMID: 35934931
• Rehan M, Kurundkar D, Kurundkar AR, Logsdon NJ, Smith SR, Chanda D, Bernard K, Sanders YY, Deshane JS, Dsouza KG, Rangarajan S, Zmijewski JW, Thannickal VJ. Restoration of SIRT3 gene expression by airway delivery resolves age-associated persistent lung fibrosis in mice. Nat Aging. 2021 Feb;1(2):205-217. PubMed PMID: 34386777
• Rehan M, Kurundkar D, Kurundkar AR, Logsdon NJ, Smith SR, Chanda D, Bernard K, Sanders YY, Deshane JS, Dsouza KG, Rangarajan S, Zmijewski JW, Thannickal VJ. Restoration of SIRT3 gene expression by airway delivery resolves age-associated persistent lung fibrosis in mice. Nat Aging. 2021 Feb;1(2):205-217. PubMed PMID: 34386777
• Locy ML, Rangarajan S, Yang S, Johnson MR, Bernard K, Kurundkar A, Bone NB, Zmijewski JW, Byun J, Pennathur S, Zhou Y, Thannickal VJ. Oxidative cross-linking of fibronectin confers protease resistance and inhibits cellular migration. Sci Signal. 2020 Aug 11;13(644). PubMed PMID: 32788339
• Rangarajan S, Thannickal VJ. Remember Me? The Bone Marrow in Pulmonary Fibrosis. Am J Respir Crit Care Med. 2019 Oct 15;200(8):959-960. PubMed PMID: 31206314
• Rangarajan S, Bone NB, Zmijewska AA, Jiang S, Park DW, Bernard K, Locy ML, Ravi S, Deshane J, Mannon RB, Abraham E, Darley-Usmar V, Thannickal VJ, Zmijewski JW. Metformin reverses established lung fibrosis in a bleomycin model. Nat Med. 2018 Aug;24(8):1121-1127. PubMed PMID: 29967351
• Rangarajan S, Lee JS. The TAMing of the Idiopathic Pulmonary Fibrosis Myofibroblast. One Step Closer?. Am J Respir Crit Care Med. 2018 Jun 1;197(11):1377-1378. PubMed PMID: 29664671

Professional Memberships

• American Thoracic Society, Member

Practice Locations

UCHealth University of Colorado Hospital (UCH)
12605 E. 16th Ave
Aurora, CO 80045
720-848-0000

Rocky Mountain Regional Veterans Administration Medical Center
1700 Wheeling St
Aurora, CO 80045
303-399-8020

Hospital Affiliation

• University of Colorado Hospital
• Veterans Affairs Medical Center

Specialty Information

Specialties

• Pulmonary Disease, Board Certification (2013)
• Critical Care Medicine, Board Certification (2014)
• Internal Medicine, Board Certification (2011)

Conditions & Treatments

• Lungs and Breathing
• Lungs and Breathing - Pulmonary Disorders
• Lungs and Breathing - Interstitial Lung Disease
• Critical Care