Won Chan Oh, PhD

Publications

• Kim J, Lee S, Jung K, Oh WC, Kim N, Son S, Jo Y, Kwon HB, Do Heo W. Intensiometric biosensors visualize the activity of multiple small GTPases in vivo. Nat Commun. 2019 Jan 14;10(1):211. PubMed PMID: 30643148
• Oh WC, Smith KR. Activity-dependent development of GABAergic synapses. Brain Res. 2018 Nov 12. [Epub ahead of print] PubMed PMID: 30439352
• Sutton LP, Orlandi C, Song C, Oh WC, Muntean BS, Xie K, Filippini A, Xie X, Satterfield R, Yaeger JDW, Renner KJ, Young SM Jr, Xu B, Kwon H, Martemyanov KA. Orphan receptor GPR158 controls stress-induced depression. Elife. 2018 Feb 8;7. PubMed PMID: 29419376
• Stein IS, Hill TC, Oh WC, Parajuli LK and Zito K. Probing the structural and functional plasticity of dendritic spines using two-photon glutamate uncaging.
• Kim J, Lee S, Jung K, Oh WC, Kim N, Son S, Jo Y, Kwon HB, Heo WD. Intensiometric biosensors visualize the activity of multiple small GTPases in vivo. Nat Commun. 2019 Jan 14;10(1):211. PubMed PMID: 30643148
• Oh WC, Smith KR. Activity-dependent development of GABAergic synapses. Brain Res. 2019 Mar 15;1707:18-26. PubMed PMID: 30439352
• Sein IS, Hill TC, Oh WC, Parajuli LK and Zito K. Two-Photon Glutamate Uncaging to Study Structural and Functional Plasticity of Dendritic Spines. Neuromethods. Multiphoton Microscopy 148: 65-85
• Ogelman R, Hwang IW, Oh WC. Cloaked caged glutamate eliminates off-target GABA-A receptor antagonism and opens a new door in neuroscience. Lab Anim (NY). 2020 Jun;49(6):177-179. PubMed PMID: 32461595
• Parajuli LK, Urakubo H, Takahashi-Nakazato A, Ogelman R, Iwasaki H, Koike M, Kwon HB, Ishii S, Oh WC, Fukazawa Y, Okabe S. Geometry and the Organizational Principle of Spine Synapses along a Dendrite. eNeuro. 2020 Nov-Dec;7(6). PubMed PMID: 33109633
• Oh WC, Rodríguez G, Asede D, Jung K, Hwang IW, Ogelman R, Bolton MM, Kwon HB. Dysregulation of the mesoprefrontal dopamine circuit mediates an early-life stress-induced synaptic imbalance in the prefrontal cortex. Cell Rep. 2021 May 4;35(5):109074. PubMed PMID: 33951422
• Dong C, Ly C, Dunlap LE, Vargas MV, Sun J, Hwang IW, Azinfar A, Oh WC, Wetsel WC, Olson DE, Tian L. Psychedelic-inspired drug discovery using an engineered biosensor. Cell. 2021 May 13;184(10):2779-2792.e18. PubMed PMID: 33915107
• Parajuli LK, Urakubo H, Takahashi-Nakazato A, Ogelman R, Iwasaki H, Koike M, Kwon HB, Ishii S, Oh WC, Fukazawa Y, Okabe S. Geometry and the Organizational Principle of Spine Synapses along a Dendrite. eNeuro. 2020 Nov-Dec;7(6). PubMed PMID: 33109633
• Jang, J., OH, W.C., and Zito, K. (2021) Induction of input-specific spine shrinkage by two-photon glutamate uncaging. / In press, STAR Protocols /
• Kim, J., Kim, S., Kim, H., Hwang, I.-W., Bae, S., Karki, S., Ogelman, R., Kim, D., Eun, J., Bang, G., Kim, J.-Y., Kajander, T., Um, J.W., OH, W.C.#, and Ko, J.# (2021) MDGA1 tunes amyloid precursor protein-mediated trans-synaptic signaling for synaptic inhibition in the hippocampus #co-corresponding author / In press, PNAS /
• Swenson, K.S., Gomez Wulschner, L. E., Hoelscher, V.M., Folts, L., Korth,K.M., OH, W.C., Bates, E.,A. (2023) Fetal cannabidiol (CBD) exposure alters thermal pain sensitivity, cognition, and prefrontal cortex excitability. Molecular Psychiatry Jul 11. doi: 10.1038/s41380-023-02130-y
• Kleinjan, M., Buchta, W., Ogelman, R., Hwang, I.-W., Kuwajima, M., Hubbard, D., Kareemo, D., Prikhodko, O., Olah, S., Gomez Wulschner, L. E., Abraham., W., Franco, S., Harris, K. , OH, W.C.#, and Kennedy, M.J.# (2022) Dually-innervated dendritic spines develop in the absence of synaptic input and resist structural plasticity through tonic inhibitory crosstalk. Neuron 2023 Feb 1;111(3):362-371.e6 #Corresponding authors
• Kleinjan MS, Buchta WC, Ogelman R, Hwang IW, Kuwajima M, Hubbard DD, Kareemo DJ, Prikhodko O, Olah SL, Gomez Wulschner LE, Abraham WC, Franco SJ, Harris KM, Oh WC, Kennedy MJ. Dually innervated dendritic spines develop in the absence of excitatory activity and resist plasticity through tonic inhibitory crosstalk. Neuron. 2023 Feb 1;111(3):362-371.e6. PubMed PMID: 36395772
• Kim J, Kim S, Kim H, Hwang IW, Bae S, Karki S, Kim D, Ogelman R, Bang G, Kim JY, Kajander T, Um JW, Oh WC, Ko J. MDGA1 negatively regulates amyloid precursor protein-mediated synapse inhibition in the hippocampus. Proc Natl Acad Sci U S A. 2022 Jan 25;119(4). PubMed PMID: 35074912
• Kim J, Wulschner LEG, Oh WC, Ko J. Trans-synaptic mechanisms orchestrated by mammalian synaptic cell adhesion molecules. Bioessays. 2022 Nov;44(11):e2200134. PubMed PMID: 36089658