Kyle Annen, DO

Associate Professor, Pathology

FacultyPhoto
Undergraduate School
  • BS, Elmhurst College (IL) (2002)
Internship
  • Advocate Illinois Masonic Medical Center Program (2008)
Residencies
  • Penn State University/Milton S Hershey Medical Center Program, Anatomic and Clinical (2009)
  • McGaw Medical Center of Northwestern University Program, Clinical (2011)
Fellowships
  • Medical College of Wisconsin Affiliated Hospitals/Children's Hospital of Wisconsin Program, Blood Banking / Transfusion Medicine (2012)
Languages
English
Department
Pathology

Publications

  • Strengthening Clinical Pathology Resident Engagement in Patient Safety Education with Prospective Auditing of Transfusion Orders Abstract ID: 4944 Final Poster ID Number: ED7
  • Samuel J, Vege S, Aeschlimann J, Lomas-Francis C, Westhoff CM, Friedman M, Annen K. Novel JK allele background associated with production of anti-JK3 during pregnancy. Transfusion. 2018 Apr;58(4):1078-1079. PubMed PMID: 29399811
  • Friedman, M.T., West, K.A., Bizargity, P., Annen, K., Jhang, J.S. Immunohematology and Transfusion Medicine, A Case Study Approach. 2nd Ed. Springer 2018.
  • 1. Ho A, Ho S, Newport M, DomBourian M, Annen K. Decreased Alloimmunization Rates in Pediatric Sickle Cell Disease Patients Despite Switching from Extended Prophylactic Matching to RH and Kell Only. Poster, Transfusion 2019-Vol. 59, S3 #P-TS-10. Poster, AABB Annual Meeting, October 2019
  • Annen K, Kuldanek S - Impact of Legalization of Cannabis in The US State of Colorado OnPerceptions and Use Prior To Blood donation, Accepted for International Congress of the ISBTmeeting, Barcelona, Spain, December 12-16, 2020
  • Tiller A, Schwartz EJ, Pasko B, Annen K - Development of a Guideline for Short-term VascularAccess for Pediatric Peripheral Blood Stem Cell Collection, Oral Abstract, Accepted for ASFAVirtual Annual meeting, September 23-25, 2020
  • Stephens S, Schwartz EJ, Pasko B, Annen K - Preliminary Data Suggests Tego© Caps Used forInpatients Receiving Therapeutic Apheresis Treatments Do Not Pose A Risk for Central LineAssociated Blood Stream Infections (CLABSI), Accepted for ASFA Virtual Annual meeting,September 23-25, 2020
  • Schwartz EJ, Gurley J, Pasko B, Annen K - Routine Magnesium Supplementation Is Not Necessaryfor Pediatric Peripheral Blood Stem Cell Collections, Accepted for ASFA Virtual Annual meeting,September 23-25, 2020
  • Sanders M, Schwartz EJ, Pasko B, Annen K - Target Hematocrit During red cell Depletion may beimpacted when replacing with 5% albumin: A case report Accepted for ASFA Virtual Annualmeeting, September 23-25, 2020
  • Pathology Outlines, Allergic and Anaphylactic Transfusion Reactions, August 19, 2020 http://www.pathologyoutlines.com/topic/transfusionmedallergic.html
  • Reppucci ML, Pickett K, Stevens J, Phillips R, Recicar J, Annen K, Moulton SL. Massive transfusion in pediatric trauma-does more blood predict mortality?. J Pediatr Surg. 2021 Oct 8. [Epub ahead of print] PubMed PMID: 34736771
  • Chauhan L, Pattee J, Ford J, Thomas C, Lesteberg K, Richards E, Bernas CA, Loi M, Dumont L, Annen K, Berg M, Zirbes M, Knight V, Miller A, Jenkins TC, Bennett TD, Monkowski D, Boxer RS, Beckham JD. A Multi-center, Prospective, Observational-cohort controlled study of Clinical Outcomes following COVID-19 Convalescent plasma therapy in hospitalized COVID-19 patients. Clin Infect Dis. 2021 Sep 21. [Epub ahead of print] PubMed PMID: 34549274
  • Editors: Cushing M, Poisson J, Bandarenko N, Yazer M, Cooling L, Annen K, Raval J, Friedman K,Campbell-Lee, S. Blood Transfusion Therapy: A Physician’s Handbook, 12th Edition, TherapeuticApheresis, AABB Press, October 3, 2020
  • Huey L, Andersen G, Merkel PA, Morrison TE, McCarthy M, DomBourian MG, Annen K, Dawson ED, Rowlen KL, Knight V. Evaluation of a multiplexed coronavirus antigen array for detection of SARS-CoV-2 specific IgG in COVID-19 convalescent plasma. J Immunol Methods. 2021 Oct;497:113104. PubMed PMID: 34303688
  • Annen K, Morrison TE*, DomBourian MG, McCarthy MK, Huey L, Merkel PA, Andersen G, Schwartz E, Knight V - Presence and Short-Term Persistence Of SARS-Cov-2 Neutralizing Antibodies In COVID-19 Convalescent Plasma Donors. Accepted for Publication in Transfusion, December 3,2020. Available on MedRxIV *co-first authors2.
  • DomBourian MG, Annen K, Huey L, Andersen G, Merkel PA, Jung S, Dominguez SR, Knight V -Analysis Of COVID-19 Convalescent Plasma for SARS-Cov-2 IgG using Two Commercial Immunoassays, Journal of Immunological Methods 2020 Aug 20:112837 PMID: 32828791
  • Annen K, DomBourian MG. Perceptions on acceptability and reported consumption of marijuana by blood donors prior to donation in the recreational use state of Colorado, USA. Vox Sang. 2021 Jul 22. [Epub ahead of print] PubMed PMID: 34291819
  • Schultz JS, McCarthy MK, Rester C, Sabourin KR, Annen K, DomBourian M, Eisenmesser E, Frazer-Abel A, Knight V, Jaenisch T, Morrison TE, Rochford R, Kedl RM. Development and Validation of a Multiplex Microsphere Immunoassay Using Dried Blood Spots for SARS-CoV-2 Seroprevalence: Application in First Responders in Colorado, USA. J Clin Microbiol. 2021 May 19;59(6). PubMed PMID: 33795412
  • Helander L, Hanna M, Annen K. Pediatric double positive anti-glomerular basement membrane antibody and anti-neutrophil cytoplasmic antibody glomerulonephritis-A case report with review of literature. J Clin Apher. 2021 Jun;36(3):505-510. PubMed PMID: 33629780
  • Taylor SC, Hurst B, Charlton CL, Bailey A, Kanji JN, McCarthy MK, Morrison TE, Huey L, Annen K, DomBourian MG, Knight V. A New SARS-CoV-2 Dual-Purpose Serology Test: Highly Accurate Infection Tracing and Neutralizing Antibody Response Detection. J Clin Microbiol. 2021 Mar 19;59(4). PubMed PMID: 33500361
  • Kuldanek S, Pasko B, DomBourian M, Annen K. Cellular Therapy in Pediatric Hematologic Malignancies. Clin Lab Med. 2021 Mar;41(1):121-132. PubMed PMID: 33494880
  • Annen K, Morrison TE, DomBourian MG, McCarthy MK, Huey L, Merkel PA, Andersen G, Schwartz E, Knight V. Presence and short-term persistence of SARS-CoV-2 neutralizing antibodies in COVID-19 convalescent plasma donors. Transfusion. 2021 Apr;61(4):1148-1159. PubMed PMID: 33452828
  • DomBourian MG, Annen K, Huey L, Andersen G, Merkel PA, Jung S, Dominguez SR, Knight V. Analysis of COVID-19 convalescent plasma for SARS-CoV-2 IgG using two commercial immunoassays. J Immunol Methods. 2020 Nov;486:112837. PubMed PMID: 32828791
  • Annen K, Zubair A, Schwartz E, Schwartz J, Szczepiorkowski ZM. What's in Your CART? Clinical insights on challenges in mononuclear cell collection for CAR-T therapy. J Clin Apher. 2020 Jun;35(3):234-235. PubMed PMID: 32186782
  • Barg-Walkow L, Annen K. Redesign of a Transfusion Issue Form Using Human Factors Science. Ergonomics in Design. May 2021. doi:10.1177/10648046211014402
  • Pasko BE, DomBourian M, Helander L, Sanders M, Annen K. Safe peripheral blood stem cell collection in patients less than 10?kg: A single-center review. J Clin Apher. 2022 Dec 7. [Epub ahead of print] PubMed PMID: 36477903
  • Helander L, McKinney C, Kelly K, Mack S, Sanders M, Gurley J, Dumont LJ, Annen K. Chronic granulomatous disease and McLeod syndrome: Stem cell transplant and transfusion support in a 2-year-old patient-a case report. Front Immunol. 2022;13:994321. PubMed PMID: 36081507
  • Kelly K, Helander L, Hazegh K, Stanley C, Moss R, Mack S, Sanders ML, Gurley J, McKinney C, Dumont LJ, Annen K. Cryopreservation of rare pediatric red blood cells for support following bone marrow transplant. Transfusion. 2022 May;62(5):954-960. PubMed PMID: 35403731
  • Reppucci ML, Pickett K, Stevens J, Phillips R, Recicar J, Annen K, Moulton SL. Massive transfusion in pediatric trauma-does more blood predict mortality?. J Pediatr Surg. 2022 Feb;57(2):308-313. PubMed PMID: 34736771
  • AABB Technical Manual, 23rd Ed, Perinatal Chapter
  • AABB Therapeutic Apheresis Handbook, 7th Edition Pediatric Chapter
  • AABB Blood Transfusion Therapy 14th Edition, Therapeutic Apheresis Chapter
  • AABB Pediatric Handbook, 7th edition ECMO and HPST chapter
  • Getting Started in Biotherapies: Collections Pediatric Chapter
  • Tabish N. Annen K, DomBourian M, Helander L, Tiller A, Sanders M, Pasko BE, Stephens S. A Breathtaking Solution: Six years of ECP to Treat Bronchiolitis Obliterans in a Pediatric Lung Transplant Patient , Journal of Clinical Apheresis Special Issue. 2024 (39):2: P-68, Poster, ASFA Annual Meeting April 17-19, 2024
  • Tabish N. Annen K, Stephens S. Two Pediatric Cases of Therapeutic Plasma Exchange to Treat Elevated Plasma-Free Hemoglobin. Journal of Clinical Apheresis Special Issue. 2024 (39):2: P-69, Poster, ASFA Annual Meeting April 17-19, 2024
  • Tabish N. Annen K, Stephens S. Draper N, Helander L, Hayes C. Schwartz E, McClendon B. Skipping at Step: Implementing Plasma Exchange Early to Avoid Aggressive Immunosuppression in a Patient With Systemic Lupus Erythematosus Complicated By Diffuse Alveolar Hemorrhage , Journal of Clinical Apheresis Special Issue. 2024 (39):2: P-70, Poster, ASFA Annual Meeting April 17-19, 2024
  • Sanders, M. Stephens S, Tiller A, Helander L, DomBourian M. Pasko BE. Annen, K. Minimal Mass Mighty Potential: Optimizing CAR-T Collections in Infants Under 10 KG. Journal of Clinical Apheresis Special Issue. 2024 (39):2: P-57, Poster, ASFA Annual Meeting April 17-19, 2024
  • Cone-Sullivan, J. Raval, J. Paroder Belenitsky, M. Zantek, N. Gupta, G. Tanchecho, Y. Thibadeaux S. Helander, L. Zhao Y. Glatt, T, Mangwana, S. Annen, K. A Large, International Survey of Apheresis Providers' Transfusion Thresholds in the Peri-therapeutic Apheresis, Transfusion 2024:64;S3: P-TA-1.
  • Standardization of Blood Product Orders Improves Patient Safety in Pediatric Transfusion Medicine: A Collaborative Project accepted to Archives of Laboratory Medicine

Professional Memberships

  • American Society for Apheresis, Member
  • AABB, Member
  • College of American Pathologists, Fellow (FCAP)
  • American Society for Clinical Pathology, Fellow (FASCP)

Practice Locations

Children's Hospital Colorado Anschutz Medical Campus
13123 East 16th Ave
Aurora, CO 80045
720-777-1234

Hospital Affiliation
  • Children's Hospital Colorado

Specialty Information

Specialties
  • Clinical, Board Certification
  • Blood Banking / Transfusion Medicine, Board Certification

School of Medicine

CU Anschutz
Fitzsimons Building

13001 East 17th Place

Aurora, CO 80045

303.724.5375

School
General
Students