Srinivas Ramachandran, PhD
Assistant Professor, Biochemistry & Molecular Genetics

Publications

• Lewis HC, Kelnhofer-Millevolte LE, Brinkley MR, Arbach HE, Arnold EA, Sanders S, Bosse JB, Ramachandran S, Avgousti DC. HSV-1 exploits host heterochromatin for nuclear egress. J Cell Biol. 2023 Sep 4;222(9). PubMed PMID: 37516914
• Fong N, Sheridan RM, Ramachandran S, Bentley DL. The pausing zone and control of RNA polymerase II elongation by Spt5: Implications for the pause-release model. Mol Cell. 2022 Oct 6;82(19):3632-3645.e4. PubMed PMID: 36206739
• Rao S, Han AL, Zukowski A, Kopin E, Sartorius CA, Kabos P, Ramachandran S. Transcription factor-nucleosome dynamics from plasma cfDNA identifies ER-driven states in breast cancer. Sci Adv. 2022 Aug 26;8(34):eabm4358. PubMed PMID: 36001652
• Rao S, Ramachandran S. A computational pipeline to visualize DNA-protein binding states using dSMF data. STAR Protoc. 2022 Jun 17;3(2):101299. PubMed PMID: 35463472
• Ahmad K, Henikoff S, Ramachandran S. Managing the Steady State Chromatin Landscape by Nucleosome Dynamics. Annu Rev Biochem. 2022 Jun 21;91:183-195. PubMed PMID: 35303789
• Rao S, Ahmad K, Ramachandran S. Cooperative binding between distant transcription factors is a hallmark of active enhancers. Mol Cell. 2021 Apr 15;81(8):1651-1665.e4. PubMed PMID: 33705711
• Satyanarayan Rao*, Amy L. Han*, Alexis Zukowski, Etana Kopin, Carol A. Sartorius, Peter Kabos#, Srinivas Ramachandran#. Mapping Transcription Factor-Nucleosome Dynamics from Plasma cfDNA. bioRxiv 2021.04.14.439883; doi: https://doi.org/10.1101/2021.04.14.439883
• Liu H, Ramachandran S, Fong N, Phang T, Lee S, Parsa P, Liu X, Harmacek L, Danhorn T, Song T, Oh S, Zhang Q, Chen Z, Zhang Q, Tu TH, Happoldt C, O'Conner B, Janknecht R, Li CY, Marrack P, Kappler J, Leach S, Zhang G. JMJD5 couples with CDK9 to release the paused RNA polymerase II. Proc Natl Acad Sci U S A. 2020 Aug 18;117(33):19888-19895. PubMed PMID: 32747552
• Zukowski A, Rao S, Ramachandran S. Phenotypes from cell-free DNA. Open Biol. 2020 Sep;10(9):200119. PubMed PMID: 32873154
• Henikoff S, Ramachandran S. Pioneers Invade the Nucleosomal Landscape. Mol Cell. 2018 Jul 19;71(2):193-194. PubMed PMID: 30028998
• Kami Ahmad*, Steven Henikoff, Srinivas Ramachandran*. Managing the steady state chromatin landscape by nucleosome dynamics. Annual Reviews Biochemistry (in press)