Christopher Ford, PhD

Publications

• Gantz SC, Ford CP, Morikawa H, Williams JT. The Evolving Understanding of Dopamine Neurons in the Substantia Nigra and Ventral Tegmental Area. Annu Rev Physiol. 2017 Sep 22. [Epub ahead of print] PubMed PMID: 28938084
• Mamaligas AA, Ford CP. Revealing a Role for NMDA Receptors in Regulating STN Inputs following the Loss of Dopamine. Neuron. 2017 Sep 13;95(6):1227-1229. PubMed PMID: 28910611
• Cai Y, Ford CP. Dopamine Cells Differentially Regulate Striatal Cholinergic Transmission across Regions through Corelease of Dopamine and Glutamate. Cell Rep. 2018 Dec 11;25(11):3148-3157.e3. PubMed PMID: 30540946
• Mulvey B, Bhatti DL, Gyawali S, Lake AM, Kriaucionis S, Ford CP, Bruchas MR, Heintz N, Dougherty JD. Molecular and Functional Sex Differences of Noradrenergic Neurons in the Mouse Locus Coeruleus. Cell Rep. 2018 May 22;23(8):2225-2235. PubMed PMID: 29791834
• Gulati S, Jin H, Masuho I, Orban T, Cai Y, Pardon E, Martemyanov KA, Kiser PD, Stewart PL, Ford CP, Steyaert J, Palczewski K. Targeting G protein-coupled receptor signaling at the G protein level with a selective nanobody inhibitor. Nat Commun. 2018 May 18;9(1):1996. PubMed PMID: 29777099
• Marcott PF, Gong S, Donthamsetti P, Grinnell SG, Nelson MN, Newman AH, Birnbaumer L, Martemyanov KA, Javitch JA, Ford CP. Regional Heterogeneity of D2-Receptor Signaling in the Dorsal Striatum and Nucleus Accumbens. Neuron. 2018 May 2;98(3):575-587.e4. PubMed PMID: 29656874
• Gantz SC, Ford CP, Morikawa H, Williams JT. The Evolving Understanding of Dopamine Neurons in the Substantia Nigra and Ventral Tegmental Area. Annu Rev Physiol. 2018 Feb 10;80:219-241. PubMed PMID: 28938084
• Gong S, Ford CP. Cholinergic Interneurons Provide a Link to Balance Excitation across Striatal Output Neurons. Neuron. 2019 Aug 7;103(3):351-353. PubMed PMID: 31394056
• Mamaligas AA, Barcomb K, Ford CP. Cholinergic Transmission at Muscarinic Synapses in the Striatum Is Driven Equally by Cortical and Thalamic Inputs. Cell Rep. 2019 Jul 23;28(4):1003-1014.e3. PubMed PMID: 31340139
• Silm K, Yang J, Marcott PF, Asensio CS, Eriksen J, Guthrie DA, Newman AH, Ford CP, Edwards RH. Synaptic Vesicle Recycling Pathway Determines Neurotransmitter Content and Release Properties. Neuron. 2019 May 22;102(4):786-800.e5. PubMed PMID: 31003725
• Liu Q, Sinnen BL, Boxer EE, Schneider MW, Grybko MJ, Buchta WC, Gibson ES, Wysoczynski CL, Ford CP, Gottschalk A, Aoto J, Tucker CL, Kennedy MJ. A Photoactivatable Botulinum Neurotoxin for Inducible Control of Neurotransmission. Neuron. 2019 Mar 6;101(5):863-875.e6. PubMed PMID: 30704911
• Zych S & FORD CP (2019). Opioid-induced adaptations of cAMP dynamics in NAc MSNs. Trends in Pharmacological Sciences. In press
• Hu D, Sun X, Liao X, Zhang X, Zarabi S, Schimmer A, Hong Y, Ford C, Luo Y, Qi X. Alpha-synuclein suppresses mitochondrial protease ClpP to trigger mitochondrial oxidative damage and neurotoxicity. Acta Neuropathol. 2019 Jun;137(6):939-960. PubMed PMID: 30877431
• Zych S, Ford CP. Opioid-Induced Adaptations of cAMP Dynamics in the Nucleus Accumbens. Trends Pharmacol Sci. 2020 Apr;41(4):230-232. PubMed PMID: 31964511
• Gong S, Fayette N, Heinsbroek JA, Ford CP. Cocaine shifts dopamine D2 receptor sensitivity to gate conditioned behaviors. Neuron. 2021 Nov 3;109(21):3421-3435.e5. PubMed PMID: 34506723
• Giannotti G, Gong S, Fayette N, Heinsbroek JA, Orfila JE, Herson PS, Ford CP, Peters J. Extinction blunts paraventricular thalamic contributions to heroin relapse. Cell Rep. 2021 Aug 24;36(8):109605. PubMed PMID: 34433067
• Cai Y, Nielsen BE, Boxer EE, Aoto J, Ford CP. Loss of nigral excitation of cholinergic interneurons contributes to parkinsonian motor impairments. Neuron. 2021 Apr 7;109(7):1137-1149.e5. PubMed PMID: 33600762
• Rodriguez-Contreras D, Gong S, Lebowitz JJ, Fedorov LM, Asad N, Dore TM, Phillips TJ, Ford CP, Williams JT, Neve KA. Gait Abnormalities and Aberrant D2 Receptor Expression and Signaling in Mice Carrying the Human Pathogenic Mutation DRD2(I212F). Mol Pharmacol. 2022 Dec 1. [Epub ahead of print] PubMed PMID: 36456191
• Barcomb K, Olah SS, Kennedy MJ, Ford CP. Properties and modulation of excitatory inputs to the locus coeruleus. J Physiol. 2022 Nov;600(22):4897-4916. PubMed PMID: 36156249
• Zych SM, Ford CP. Divergent properties and independent regulation of striatal dopamine and GABA co-transmission. Cell Rep. 2022 May 17;39(7):110823. PubMed PMID: 35584679
• Jain S, Yee AG, Maas J, Gierok S, Xu H, Stansil J, Eriksen J, Nelson AB, Silm K, Ford CP, Edwards RH. Adaptor protein-3 produces synaptic vesicles that release phasic dopamine. Proc Natl Acad Sci U S A. 2023 Oct 17;120(42):e2309843120. PubMed PMID: 37812725
• Barcomb K, Ford CP. Alterations in neurotransmitter co-release in Parkinson's disease. Exp Neurol. 2023 Dec;370:114562. PubMed PMID: 37802381
• Rodriguez-Contreras D, Gong S, Lebowitz JJ, Fedorov LM, Asad N, Dore TM, Phillips TJ, Ford CP, Williams JT, Neve KA. Gait Abnormalities and Aberrant D2 Receptor Expression and Signaling in Mice Carrying the Human Pathogenic Mutation DRD2(I212F). Mol Pharmacol. 2023 Mar;103(3):188-198. PubMed PMID: 36456191