Yuki Fujiwara, MD, PhD

Assistant Adjoint Professor, Surgery-Surgical Oncology

FacultyPhoto
Medical School
  • MD, The Jikei University School of Medicine, Tokyo, Japan (2007)
Graduate School
  • PhD, Jikei University School of Medicine, The (2012)
Languages
English, Japanese
Department
Surgery-Surgical Oncology

Publications

  • Fujiwara Y, Torphy RJ, Sun Y, Miller EN, Ho F, Borcherding N, Wu T, Torres RM, Zhang W, Schulick RD, Zhu Y. The GPR171 pathway suppresses T cell activation and limits antitumor immunity. Nat Commun. 2021 Oct 6;12(1):5857. PubMed PMID: 34615877
  • Sun Y, Chen W, Torphy RJ, Yao S, Zhu G, Lin R, Lugano R, Miller EN, Fujiwara Y, Bian L, Zheng L, Anand S, Gao F, Zhang W, Ferrara SE, Goodspeed AE, Dimberg A, Wang XJ, Edil BH, Barnett CC, Schulick RD, Chen L, Zhu Y. Blockade of the CD93 pathway normalizes tumor vasculature to facilitate drug delivery and immunotherapy. Sci Transl Med. 2021 Jul 28;13(604). PubMed PMID: 34321321
  • Haruki K, Furukawa K, Fujiwara Y, Taniai T, Hamura R, Shirai Y, Yasuda J, Shiozaki H, Onda S, Gocho T, Shiba H, Usuba T, Nakabayashi Y, Fujioka S, Okamoto T, Ikegami T. Effectiveness of Anatomical Resection for Small Hepatocellular Carcinoma: a Propensity Score-Matched Analysis of a Multi-institutional Database. J Gastrointest Surg. 2021 Nov;25(11):2835-2841. PubMed PMID: 33772400
  • Halpern AL, Fitz JG, Fujiwara Y, Yi J, Anderson AL, Zhu Y, Schulick RD, El Kasmi KC, Barnett CC Jr. Hepatic thermal injury promotes colorectal cancer engraftment in C57/black 6 mice. Am J Physiol Cell Physiol. 2021 Jan 1;320(1):C142-C151. PubMed PMID: 33175574
  • Taniai T, Haruki K, Hamura R, Fujiwara Y, Furukawa K, Gocho T, Shiba H, Yanaga K. The Prognostic Significance of C-reactive Protein-To-Lymphocyte Ratio in Colorectal Liver Metastases. J Surg Res. 2021 Feb;258:414-421. PubMed PMID: 33109402
  • Tsunematsu M, Haruki K, Fujiwara Y, Furukawa K, Onda S, Matsumoto M, Gocho T, Shiba H, Yanaga K. Preoperative controlling nutritional status (CONUT) score predicts long-term outcomes in patients with non-B non-C hepatocellular carcinoma after curative hepatic resection. Langenbecks Arch Surg. 2021 Feb;406(1):99-107. PubMed PMID: 32936328
  • Oba A, Wu YHA, Lieu CH, Meguid C, Colborn KL, Beaty L, Al-Musawi MH, Davis SL, Leal AD, Purcell T, King G, Wooten ES, Fujiwara Y, Goodman KA, Schefter T, Karam SD, Gleisner AL, Ahrendt S, Leong S, Messersmith WA, Schulick RD, Del Chiaro M. Outcome of neoadjuvant treatment for pancreatic cancer in elderly patients: comparative, observational cohort study. Br J Surg. 2021 Aug 19;108(8):976-982. PubMed PMID: 34155509
  • Halpern AL, Fitz JG, Fujiwara Y, Yi J, Anderson AL, Zhu Y, Schulick RD, El Kasmi KC, Barnett CC Jr. Hepatic thermal injury promotes colorectal cancer engraftment in C57/black 6 mice. Am J Physiol Cell Physiol. 2021 Jan 1;320(1):C142-C151. PubMed PMID: 33175574
  • Taniai T, Haruki K, Hamura R, Fujiwara Y, Furukawa K, Gocho T, Shiba H, Yanaga K. The Prognostic Significance of C-reactive Protein-To-Lymphocyte Ratio in Colorectal Liver Metastases. J Surg Res. 2021 Feb;258:414-421. PubMed PMID: 33109402
  • Tsunematsu M, Haruki K, Fujiwara Y, Furukawa K, Onda S, Matsumoto M, Gocho T, Shiba H, Yanaga K. Preoperative controlling nutritional status (CONUT) score predicts long-term outcomes in patients with non-B non-C hepatocellular carcinoma after curative hepatic resection. Langenbecks Arch Surg. 2021 Feb;406(1):99-107. PubMed PMID: 32936328
  • Torphy RJ, Fujiwara Y, Schulick RD. Pancreatic cancer treatment: better, but a long way to go. Surg Today. 2020 Oct;50(10):1117-1125. PubMed PMID: 32474642
  • Furukawa K, Shiba H, Hamura R, Haruki K, Fujiwara Y, Usuba T, Nakabayashi Y, Misawa T, Okamoto T, Yanaga K. Prognostic Factors in Patients With Recurrent Pancreatic Cancer: A Multicenter Database Analysis. Anticancer Res. 2020 Jan;40(1):293-298. PubMed PMID: 31892579
  • Fujiwara Y, Haruki K, Hamura R, Horiuchi T, Shirai Y, Furukawa K, Gocho T, Shiba H, Yanaga K. A Novel Prognostic Score Combining Preoperative Biliary Drainage and Inflammatory Status for Patients with Periampullary Cancers. J Gastrointest Surg. 2020 Apr;24(4):813-822. PubMed PMID: 31062271
  • Torphy RJ, Fujiwara Y, Schulick RD. Pancreatic cancer treatment: better, but a long way to go. Surg Today. 2020 Oct;50(10):1117-1125. PubMed PMID: 32474642
  • Furukawa K, Shiba H, Hamura R, Haruki K, Fujiwara Y, Usuba T, Nakabayashi Y, Misawa T, Okamoto T, Yanaga K. Prognostic Factors in Patients With Recurrent Pancreatic Cancer: A Multicenter Database Analysis. Anticancer Res. 2020 Jan;40(1):293-298. PubMed PMID: 31892579
  • Fujiwara Y, Haruki K, Hamura R, Horiuchi T, Shirai Y, Furukawa K, Gocho T, Shiba H, Yanaga K. A Novel Prognostic Score Combining Preoperative Biliary Drainage and Inflammatory Status for Patients with Periampullary Cancers. J Gastrointest Surg. 2020 Apr;24(4):813-822. PubMed PMID: 31062271
  • Horiuchi T, Haruki K, Shiba H, Sakamoto T, Saito N, Shirai Y, Iwase R, Fujiwara Y, Yanaga K. Assessment of Outcome of Hepatic Resection for Extremely Elderly Patients With a Hepatic Malignancy. Anticancer Res. 2019 Sep;39(9):5143-5148. PubMed PMID: 31519626
  • Horiuchi T, Haruki K, Shiba H, Sakamoto T, Saito N, Shirai Y, Iwase R, Fujiwara Y, Yanaga K. Assessment of Outcome of Hepatic Resection for Extremely Elderly Patients With a Hepatic Malignancy. Anticancer Res. 2019 Nov;39(11):6325-6332. PubMed PMID: 31704863
  • Suzuki F, Fujiwara Y, Hamura R, Haruki K, Sakamoto T, Shiba H, Yanaga K. Combination of Distance from Superior Mesenteric Artery and Serum CA19-9 as a Novel Prediction of Local Recurrence in Patients With Pancreatic Cancer Following Resection. Anticancer Res. 2019 Mar;39(3):1469-1478. PubMed PMID: 30842184
  • Fujiwara Y, Haruki K, Shiba H, Hamura R, Shirai Y, Furukawa K, Gocho T, Yanaga K. The Comparison of Inflammation-Based Prognostic Scores in Patients With Extrahepatic Bile Duct Cancer After Pancreaticoduodenectomy. J Surg Res. 2019 Jun;238:102-112. PubMed PMID: 30769246
  • Tian Y, Sun Y, Gao F, Koenig MR, Sunderland A, Fujiwara Y, Torphy RJ, Chen L, Edil BH, Schulick RD, Zhu Y. CD28H expression identifies resident memory CD8 + T cells with less cytotoxicity in human peripheral tissues and cancers. Oncoimmunology. 2019;8(2):e1538440. PubMed PMID: 30713797
  • Fujiwara Y, Haruki K, Shiba H, Hamura R, Horiuchi T, Shirai Y, Furukawa K, Gocho T, Yanaga K. C-Reactive Protein-based Prognostic Measures Are Superior at Predicting Survival Compared with Peripheral Blood Cell Count-based Ones in Patients After Curative Resection for Pancreatic Cancer. Anticancer Res. 2018 Nov;38(11):6491-6499. PubMed PMID: 30396977
  • Haruki K, Shiba H, Saito N, Horiuchi T, Shirai Y, Fujiwara Y, Furukawa K, Sakamoto T, Yanaga K. Risk stratification using a novel liver functional reserve score of combination prothrombin time-international normalized ratio to albumin ratio and albumin in patients with hepatocellular carcinoma. Surgery. 2018 Sep;164(3):404-410. PubMed PMID: 29754978
  • Fujiwara Y, Sun Y, Torphy RJ, He J, Yanaga K, Edil BH, Schulick RD, Zhu Y. Pomalidomide Inhibits PD-L1 Induction to Promote Antitumor Immunity. Cancer Res. 2018 Dec 1;78(23):6655-6665. PubMed PMID: 30315115
  • Haruki K, Shiba H, Shimada Y, Shirai Y, Iwase R, Fujiwara Y, Uwagawa T, Ohashi T, Yanaga K. Glycogen synthase kinase-3ß activity plays a key role in the antitumor effect of nafamostat mesilate in pancreatic cancer cells. Ann Gastroenterol Surg. 2018 Jan;2(1):65-71. PubMed PMID: 29863120
  • Haruki K, Shiba H, Horiuchi T, Sakamoto T, Gocho T, Fujiwara Y, Furukawa K, Misawa T, Yanaga K. Impact of the C-reactive protein to albumin ratio on long-term outcomes after hepatic resection for colorectal liver metastases. Am J Surg. 2017 Oct;214(4):752-756. PubMed PMID: 28187858
  • Haruki K, Shiba H, Fujiwara Y, Furukawa K, Iida T, Ohkuma M, Ogawa M, Ishida Y, Misawa T, Yanaga K. Preoperative peripheral blood neutrophil count predicts long-term outcomes following hepatic resection for colorectal liver metastases. Oncol Lett. 2017 May;13(5):3688-3694. PubMed PMID: 28521471
  • Matsumoto M, Nakabayashi Y, Fujiwara Y, Funamizu N, Noaki R, Eto S, Sugano H, Otsuka M, Yanaga K. Duration of Preoperative Biliary Drainage as a Prognostic Factor After Pancreaticoduodenectomy for Pancreatic Head Cancer. Anticancer Res. 2017 Jun;37(6):3215-3219. PubMed PMID: 28551667
  • Shiba H, Horiuchi T, Sakamoto T, Furukawa K, Shirai Y, Iida T, Fujiwara Y, Haruki K, Yanaga K. Glasgow prognostic score predicts therapeutic outcome after hepatic resection for hepatocellular carcinoma. Oncol Lett. 2017 Jul;14(1):293-298. PubMed PMID: 28693167
  • Shirai Y, Shiba H, Haruki K, Horiuchi T, Saito N, Fujiwara Y, Sakamoto T, Uwagawa T, Yanaga K. Preoperative Platelet-to-Albumin Ratio Predicts Prognosis of Patients with Pancreatic Ductal Adenocarcinoma After Pancreatic Resection. Anticancer Res. 2017 Feb;37(2):787-793. PubMed PMID: 28179331
  • Fujiwara Y, Shiba H, Nakabayashi Y, Otsuka M, Yanaga K. Hepatic abscess in the Spiegel lobe caused by foreign body penetration: report of a case report. Surg Case Rep. 2017 Dec;3(1):24. PubMed PMID: 28188512
  • Furukawa K, Shiba H, Horiuchi T, Shirai Y, Haruki K, Fujiwara Y, Sakamoto T, Gocho T, Yanaga K. Survival benefit of hepatic resection for hepatocellular carcinoma beyond the Barcelona Clinic Liver Cancer classification. J Hepatobiliary Pancreat Sci. 2017 Apr;24(4):199-205. PubMed PMID: 28160422
  • Haruki K, Shiba H, Shirai Y, Horiuchi T, Iwase R, Fujiwara Y, Furukawa K, Misawa T, Yanaga K. The C-reactive Protein to Albumin Ratio Predicts Long-Term Outcomes in Patients with Pancreatic Cancer After Pancreatic Resection. World J Surg. 2016 Sep;40(9):2254-60. PubMed PMID: 26956901
  • Furukawa K, Gocho T, Shirai Y, Iwase R, Haruki K, Fujiwara Y, Shiba H, Misawa T, Yanaga K. The Decline of Amylase Level of Pancreatic Juice After Pancreaticoduodenectomy Predicts Postoperative Pancreatic Fistula. Pancreas. 2016 Nov;45(10):1474-1477. PubMed PMID: 27518469
  • Sakamoto T, Ishii Y, Shiba H, Furukawa K, Fujiwara Y, Haruki K, Iwase R, Shirai Y, Yanaga K. Inhibitory Effect of Anti-rheumatic Drug Iguratimod for Hepatocellular Carcinogenesis by Inhibition of Serum Interleukin-8 Production. Anticancer Res. 2016 Jul;36(7):3301-6. PubMed PMID: 27354586
  • Shirai Y, Shiba H, Iwase R, Haruki K, Fujiwara Y, Furukawa K, Uwagawa T, Ohashi T, Yanaga K. Dual inhibition of nuclear factor kappa-B and Mdm2 enhance the antitumor effect of radiation therapy for pancreatic cancer. Cancer Lett. 2016 Jan 28;370(2):177-84. PubMed PMID: 26546875
  • Haruki K, Shiba H, Horiuchi T, Shirai Y, Iwase R, Fujiwara Y, Furukawa K, Misawa T, Yanaga K. Neutrophil to Lymphocyte Ratio Predicts Therapeutic Outcome After Pancreaticoduodenectomy for Carcinoma of the Ampulla of Vater. Anticancer Res. 2016 Jan;36(1):403-8. PubMed PMID: 26722073
  • Fujiwara Y, Suzuki F, Kanehira M, Futagawa Y, Okamoto T, Yanaga K. Radical resection of T1 pancreatic adenocarcinoma with a pseudocyst of the tail due to acute obstructive pancreatitis: report of a case. Surg Case Rep. 2016 Dec;2(1):144. PubMed PMID: 27900729
  • Takakura K, Ito Z, Suka M, Kanai T, Matsumoto Y, Odahara S, Matsudaira H, Haruki K, Fujiwara Y, Saito R, Gocho T, Nakashiro K, Hamakawa H, Okamoto M, Kajihara M, Misawa T, Ohkusa T, Koido S. Comprehensive assessment of the prognosis of pancreatic cancer: peripheral blood neutrophil-lymphocyte ratio and immunohistochemical analyses of the tumour site. Scand J Gastroenterol. 2016;51(5):610-7. PubMed PMID: 26679084
  • Furukawa K, Shiba H, Shirai Y, Horiuchi T, Iwase R, Haruki K, Fujiwara Y, Misawa T, Yanaga K. Negative Impact of Preoperative Endoscopic Biliary Drainage on Prognosis of Pancreatic Ductal Adenocarcinoma After Pancreaticoduodenectomy. Anticancer Res. 2015 Sep;35(9):5079-83. PubMed PMID: 26254410
  • Haruki K, Shiba H, Horiuchi T, Shirai Y, Iwase R, Fujiwara Y, Furukawa K, Misawa T, Yanaga K. Preoperative Change in Peripheral Blood Monocyte Count May Predict Long-term Outcomes After Pancreaticoduodenectomy for Bile Duct Cancer. Anticancer Res. 2015 Sep;35(9):4961-6. PubMed PMID: 26254395
  • Shiba H, Misawa T, Fujiwara Y, Futagawa Y, Furukawa K, Haruki K, Iwase R, Iida T, Yanaga K. Glasgow prognostic score predicts outcome after surgical resection of gallbladder cancer. World J Surg. 2015 Mar;39(3):753-8. PubMed PMID: 25348884
  • Fujiwara Y, Shiba H, Shirai Y, Iwase R, Haruki K, Furukawa K, Futagawa Y, Misawa T, Yanaga K. Perioperative serum albumin correlates with postoperative pancreatic fistula after pancreaticoduodenectomy. Anticancer Res. 2015 Jan;35(1):499-503. PubMed PMID: 25550594
  • Fujiwara Y, Shiba H, Uwagawa T, Futagawa Y, Misawa T, Yanaga K. Radical Resection of a Primarily Unresectable Pancreatic Cancer After Neoadjuvant Chemotherapy Using Gemcitabine, TS-1, and Nafamostat Mesilate; Report of a Case. Int Surg. 2015 Feb;100(2):287-91. PubMed PMID: 25692432
  • Tanaka M, Tomikawa M, Nakamura M, Nakamura Y, Misawa T, Akahoshi T, Kinjyo N, Sumiyoshi H, Tsutsumi K, Tsutsumi N, Nakashima H, Higashida M, Fujiwara Y, Matsushita A, Matsumoto M. Gastroenterological Surgery: Pancreas. Asian J Endosc Surg. 2015 Aug;8(3):239-42. PubMed PMID: 26303728
  • Shirai Y, Shiba H, Sakamoto T, Horiuchi T, Haruki K, Fujiwara Y, Futagawa Y, Ohashi T, Yanaga K. Preoperative platelet to lymphocyte ratio predicts outcome of patients with pancreatic ductal adenocarcinoma after pancreatic resection. Surgery. 2015 Aug;158(2):360-5. PubMed PMID: 26032829
  • Shiba H, Haruki K, Futagawa Y, Iida T, Furukawa K, Fujiwara Y, Wakiyama S, Misawa T, Yanaga K. Central bisegmentectomy for malignant liver tumors: experience in 8 patients. Int Surg. 2014 Sep-Oct;99(5):612-5. PubMed PMID: 25216430
  • Fujiwara Y, Misawa T, Shiba H, Shirai Y, Iwase R, Haruki K, Furukawa K, Futagawa Y, Yanaga K. Postoperative peripheral absolute blood lymphocyte-to-monocyte ratio predicts therapeutic outcome after pancreatic resection in patients with pancreatic adenocarcinoma. Anticancer Res. 2014 Sep;34(9):5163-8. PubMed PMID: 25202109
  • Ito E, Wakiyama S, Fujiwara Y, Ikegami M, Yanaga K. [A case of long-term survival without recurrence from an unknown primary carcinoma after resection of lymph node metastases]. Nihon Shokakibyo Gakkai Zasshi. 2014 Oct;111(10):1990-6. PubMed PMID: 25283228
  • Misawa T, Shiba H, Fujiwara Y, Futagawa Y, Harada T, Ikegami M, Yanaga K. Massive splenomegaly caused by cavernous hemangiomas associated with Klippel-Trenaunay syndrome: report of a case. Surg Today. 2014 Jan;44(1):197-200. PubMed PMID: 24254059
  • Shiba H, Misawa T, Fujiwara Y, Futagawa Y, Furukawa K, Haruki K, Iida T, Iwase R, Yanaga K. Negative impact of fresh-frozen plasma transfusion on prognosis of pancreatic ductal adenocarcinoma after pancreatic resection. Anticancer Res. 2013 Sep;33(9):4041-7. PubMed PMID: 24023348
  • Haruki K, Shiba H, Fujiwara Y, Furukawa K, Iwase R, Uwagawa T, Misawa T, Ohashi T, Yanaga K. Inhibition of nuclear factor-?B enhances the antitumor effect of tumor necrosis factor-a gene therapy for hepatocellular carcinoma in mice. Surgery. 2013 Sep;154(3):468-78. PubMed PMID: 23972653
  • Iwase R, Haruki K, Fujiwara Y, Furukawa K, Shiba H, Uwagawa T, Misawa T, Ohashi T, Yanaga K. Combination chemotherapy of nafamostat mesylate with gemcitabine for gallbladder cancer targeting nuclear factor-?B activation. J Surg Res. 2013 Sep;184(1):605-12. PubMed PMID: 23830367
  • Shirai Y, Shiba H, Fujiwara Y, Eto K, Misawa T, Yanaga K. Hepatic inflammatory pseudotumor with elevated serum CA19-9 level mimicking liver metastasis from rectal cancer: report of a case. Int Surg. 2013 Oct-Dec;98(4):324-9. PubMed PMID: 24229018
  • Shiba H, Ishida Y, Fujiwara Y, Wakiyama S, Gocho T, Ito R, lida T, Suzuki F, Furukawa K, Haruki K, Misawa T, Yanaga K. Comparison of hepatocellular carcinoma with cirrhosis patients undergoing hepatic resection between hepatitis B and C infection. Hepatogastroenterology. 2013 Oct;60(127):1746-8. PubMed PMID: 24634946
  • Shiba H, Ishida Y, Fujiwara Y, Wakiyama S, Gocho T, Ito R, Sakamoto T, Tsutsui N, lida T, Matsumoto M, Furukawa K, Haruki K, Hirohara S, Misawa T, Yanaga K. Practice to minimize the use of blood products improve outcome after hepatic resection for hepatocellular carcinoma. Hepatogastroenterology. 2013 Oct;60(127):1681-3. PubMed PMID: 24634937
  • Haruki K, Shiba H, Fujiwara Y, Furukawa K, Wakiyama S, Ogawa M, Ishida Y, Misawa T, Yanaga K. Practice to extend indication of hepatic resection for colorectal liver metastasis. Hepatogastroenterology. 2013 Oct;60(127):1633-8. PubMed PMID: 24634934
  • Uwagawa T, Misawa T, Fujiwara Y, Furukawa K, Tsutsui N, Kitamura H, Shiba H, Futagawa Y, Aiba K, Yanaga K. Erlotinib-induced thrombocytosis in patients with recurrence of pancreatic cancer after distal pancreatectomy. Pancreas. 2013 Oct;42(7):1196-7. PubMed PMID: 24048463
  • Fujiwara Y, Misawa T, Shiba H, Shirai Y, Iwase R, Haruki K, Furukawa K, Futagawa Y, Yanaga K. A novel postoperative inflammatory score predicts postoperative pancreatic fistula after pancreatic resection. Anticancer Res. 2013 Nov;33(11):5005-10. PubMed PMID: 24222143
  • Misawa T, Imazu H, Fujiwara Y, Kitamura H, Tsutsui N, Ito R, Shiba H, Futagawa Y, Wakiyama S, Ishida Y, Yanaga K. Efficacy of nasopancreatic stenting prior to laparoscopic enucleation of pancreatic neuroendocrine tumor. Asian J Endosc Surg. 2013 May;6(2):140-2. PubMed PMID: 23602001
  • Gocho T, Uwagawa T, Furukawa K, Haruki K, Fujiwara Y, Iwase R, Misawa T, Ohashi T, Yanaga K. Combination chemotherapy of serine protease inhibitor nafamostat mesilate with oxaliplatin targeting NF-?B activation for pancreatic cancer. Cancer Lett. 2013 Jun 1;333(1):89-95. PubMed PMID: 23348695
  • Shiba H, Ishida Y, Haruki K, Furukawa K, Fujiwara Y, Iwase R, Ohkuma M, Ogawa M, Misawa T, Yanaga K. Negative impact of fresh-frozen plasma transfusion on prognosis after hepatic resection for liver metastases from colorectal cancer. Anticancer Res. 2013 Jun;33(6):2723-8. PubMed PMID: 23749932
  • Haruki K, Shiba H, Fujiwara Y, Furukawa K, Iwase R, Uwagawa T, Misawa T, Ohashi T, Yanaga K. Inhibition of nuclear factor-?B enhances the antitumor effect of paclitaxel against gastric cancer with peritoneal dissemination in mice. Dig Dis Sci. 2013 Jan;58(1):123-31. PubMed PMID: 22806547
  • Shiba H, Misawa T, Fujiwara Y, Futagawa Y, Furukawa K, Haruki K, Iwase R, Wakiyama S, Ishida Y, Yanaga K. Glasgow prognostic score predicts therapeutic outcome after pancreaticoduodenectomy for carcinoma of the ampulla of vater. Anticancer Res. 2013 Jun;33(6):2715-21. PubMed PMID: 23749931
  • Shiba H, Furukawa K, Fujiwara Y, Futagawa Y, Haruki K, Wakiyama S, Ishida Y, Misawa T, Yanaga K. Postoperative peak serum C-reactive protein predicts outcome of hepatic resection for hepatocellular carcinoma. Anticancer Res. 2013 Feb;33(2):705-9. PubMed PMID: 23393371
  • Fujiwara Y, Shiba H, Iwase R, Haruki K, Furukawa K, Uwagawa T, Misawa T, Ohashi T, Yanaga K. Inhibition of nuclear factor kappa-B enhances the antitumor effect of combination treatment with tumor necrosis factor-alpha gene therapy and gemcitabine for pancreatic cancer in mice. J Am Coll Surg. 2013 Feb;216(2):320-32.e3. PubMed PMID: 23219147
  • Furukawa K, Uwagawa T, Haruki K, Fujiwara Y, Iida T, Shiba H, Misawa T, Ohashi T, Yanaga K. Nuclear factor ?B activity correlates with the progression and prognosis of pancreatic cancer in a mouse model. Surg Today. 2013 Feb;43(2):171-7. PubMed PMID: 22892758
  • Iwase R, Shiba H, Haruki K, Fujiwara Y, Furukawa K, Futagawa Y, Wakiyama S, Misawa T, Yanaga K. Post-operative lymphocyte count may predict the outcome of radical resection for gallbladder carcinoma. Anticancer Res. 2013 Aug;33(8):3439-44. PubMed PMID: 23898116
  • Haruki K, Shiba H, Fujiwara Y, Furukawa K, Wakiyama S, Ogawa M, Ishida Y, Misawa T, Yanaga K. Postoperative peripheral blood monocyte count correlates with postoperative bile leakage in patients with colorectal liver metastases after hepatic resection. Langenbecks Arch Surg. 2013 Aug;398(6):851-5. PubMed PMID: 23640608
  • Haruki K, Shiba H, Fujiwara Y, Furukawa K, Wakiyama S, Ogawa M, Ishida Y, Misawa T, Yanaga K. Negative impact of surgical site infection on long-term outcomes after hepatic resection for colorectal liver metastases. Anticancer Res. 2013 Apr;33(4):1697-703. PubMed PMID: 23564818
  • Haruki K, Shiba H, Fujiwara Y, Furukawa K, Wakiyama S, Ogawa M, Ishida Y, Misawa T, Yanaga K. Perioperative change in peripheral blood monocyte count may predict prognosis in patients with colorectal liver metastasis after hepatic resection. J Surg Oncol. 2012 Jul 1;106(1):31-5. PubMed PMID: 22231029
  • Furukawa K, Shiba H, Haruki K, Fujiwara Y, Iida T, Mitsuyama Y, Ogawa M, Ishida Y, Misawa T, Yanaga K. The Glasgow prognostic score is valuable for colorectal cancer with both synchronous and metachronous unresectable liver metastases. Oncol Lett. 2012 Aug;4(2):324-328. PubMed PMID: 22844378
  • Mitsuyama Y, Shiba H, Haruki K, Fujiwara Y, Furukawa K, Iida T, Hayashi T, Ogawa M, Ishida Y, Misawa T, Kashiwagi H, Yanaga K. Carcinoembryonic antigen and carbohydrate antigen 19-9 are prognostic predictors of colorectal cancer with unresectable liver metastasis. Oncol Lett. 2012 Apr 1;3(4):767-771. PubMed PMID: 22740990
  • Misawa T, Ito R, Futagawa Y, Fujiwara Y, Kitamura H, Tsutsui N, Shiba H, Wakiyama S, Ishida Y, Yanaga K. Single-incision laparoscopic distal pancreatectomy with or without splenic preservation: how we do it. Asian J Endosc Surg. 2012 Nov;5(4):195-9. PubMed PMID: 23095300
  • Furukawa K, Uwagawa T, Iwase R, Haruki K, Fujiwara Y, Gocho T, Shiba H, Misawa T, Yanaga K. Prognostic factors of unresectable pancreatic cancer treated with nafamostat mesilate combined with gemcitabine chemotherapy. Anticancer Res. 2012 Nov;32(11):5121-6. PubMed PMID: 23155291
  • Fujiwara Y, Furukawa K, Haruki K, Shimada Y, Iida T, Shiba H, Uwagawa T, Ohashi T, Yanaga K. Nafamostat mesilate can prevent adhesion, invasion and peritoneal dissemination of pancreatic cancer thorough nuclear factor kappa-B inhibition. J Hepatobiliary Pancreat Sci. 2011 Sep;18(5):731-9. PubMed PMID: 21484229
  • Fujiwara Y, Furukawa K, Shimada Y, Iida T, Shiba H, Uwagawa T, Misawa T, Ohashi T, Yanaga K. Combination paclitaxel and inhibitor of nuclear factor ?B activation improves therapeutic outcome for model mice with peritoneal dissemination of pancreatic cancer. Pancreas. 2011 May;40(4):600-7. PubMed PMID: 21343836
  • Furukawa K, Ohashi T, Haruki K, Fujiwara Y, Iida T, Shiba H, Uwagawa T, Kobayashi H, Yanaga K. Combination treatment using adenovirus vector-mediated tumor necrosis factor-alpha gene transfer and a NF-?B inhibitor for pancreatic cancer in mice. Cancer Lett. 2011 Jul 1;306(1):92-8. PubMed PMID: 21482023
  • Furukawa K, Iida T, Shiba H, Fujiwara Y, Uwagawa T, Shimada Y, Misawa T, Ohashi T, Yanaga K. Anti-tumor effect by inhibition of NF-kappaB activation using nafamostat mesilate for pancreatic cancer in a mouse model. Oncol Rep. 2010 Oct;24(4):843-50. PubMed PMID: 20811662
  • Fujiwara Y, Shiba H, Furukawa K, Iida T, Sakamoto T, Gocho T, Wakiyama S, Hirohara S, Ishida Y, Misawa T, Ohashi T, Yanaga K. Perioperative change in white blood cell count predicts outcome of hepatic resection for hepatocellular carcinoma. J Hepatobiliary Pancreat Sci. 2010 Nov;17(6):892-7. PubMed PMID: 20449611
  • Fujiwara Y, Shiba H, Furukawa K, Iida T, Haruki K, Gocho T, Wakiyama S, Hirohara S, Ishida Y, Misawa T, Ohashi T, Yanaga K. Glasgow prognostic score is related to blood transfusion requirements and post-operative complications in hepatic resection for hepatocellular carcinoma. Anticancer Res. 2010 Dec;30(12):5129-36. PubMed PMID: 21187501

Specialty Information

Specialties
  • Board Certified in General Surgery, JAPAN, Board Certification (2014)
  • Board Certified Surgeon in Gastroenterology, JAPAN, Board Certification (2015)
  • Board Certificated as a Director surgeon in Gastroenterology, JAPAN, Board Certification (2020)
  • ECFMG certificate, Certificate (2021)

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