Amanda Piquet, MD

Professional Titles

• Director and Celine Dion Foundation Endowed Chair in Autoimmune Neurology

Research Interests

Publications

• Milano C, Saylam E, Papi C, Marmolejo L, Sankovic A, Reinecke R, Kerstens J, Pizzanelli C, Simabukuro MM, Benaiteau M, Joubert B, Gastaldi M, Dutra LA, Leypoldt F, Jansen M, Kawachi I, Akiyama H, Boy N, Bozzetti S, Christensen PB, Businaro P, Dinoto A, Friedman-Korn T, Fujiwara U, Fukumoto T, Fuse K, Hooshmand SI, Hurst L, Iorio R, Korn-Lubetzki I, Rodrigues AFL, Mariotto S, Michael J, Morimoto Y, Neuteboom RF, Piquet AL, Rossetti AO, Rumpler-Kreiner S, Santoro JD, Schwendinger F, Shen B, Syrbe S, Troger J, Wagner I, Bien CG, Martinez-Hernandez E, Armangue T, Höftberger R, Iizuka T, Titulaer MJ, Honnorat J, Graus F, Dalmau JO, Magaña S, Spatola M. Clinical Characterization and Long-Term Outcome in Children and Adults With Anti-AMPA Receptor Encephalitis. Neurol Neuroimmunol Neuroinflamm. 2025 Sep;12(5):e200453. PubMed PMID: 40680249
• Cronin JE, Ung TH, Piquet AL, Money KM. Evaluation of Brain Abscess Prognostic Factors and Role of Surgical Intervention Within a Single Health System. Neurohospitalist. 2025 Jul 2;:19418744251353544. [Epub ahead of print] PubMed PMID: 40621153
• Ardakani RV, Crane PD, Pastula DM, Chauhan L, Matthews E, Money KM, Shah A, Piquet AL, Gross RH, Carlson AM, Tyler KL, Corboy JR, Alvarez E, Wolf AB. West Nile Virus Neuroinvasive Disease in Patients Treated With Anti-CD20 Therapies. Neurol Clin Pract. 2025 Aug;15(4):e200489. PubMed PMID: 40584641
• Borko TL, Winters P, Money KM, Sillau S, Eggmann S, Selva S, Ritchie A, Kammeyer R, Owens GP, Bennett JL, Piquet AL. Long-term outcomes in leucine-rich glioma inactivated-1 autoimmune encephalitis and associated biomarkers of inflammation and neuronal and glial injury. Front Neurol. 2025;16:1583892. PubMed PMID: 40470500
• Manes C, Guerrero Moreno M, Cimons J, D'Antonio MA, Brunetti TM, Harbell MG, Selva S, Mizenko C, Borko TL, Lasda EL, Hesselberth JR, Hsieh EW, Verneris MR, Piquet AL, Gapin L, Kedl RM, Klarquist J. B cells shape naive CD8 T cell programming. J Clin Invest. 2025 Jun 16;135(12). PubMed PMID: 40244703
• Schmitt BL, Chauhan L, Piquet AL, Tyler KL, Pastula DM. An Overview of the Dengue Viruses. Neurohospitalist. 2025 Apr 14;:19418744251334717. [Epub ahead of print] PubMed PMID: 40242592
• Carlson AM, Sollero CEV, Wolf AB, Sillau S, Schmitt BL, Money KM, Nair KV, Piquet AL, Bennett JL. The epidemiology and clinical presentation of seropositive neuromyelitis optica spectrum disorder in a US population. Ann Clin Transl Neurol. 2025 Jan;12(1):169-179. PubMed PMID: 39708292
• Crane PD, Sillau S, Dreher R, Fix R, Winters P, Van Coevering R, Engebretson E, Valdez B, Matthews E, Nair KV, Carlson AM, Piquet AL. Population-Based Study of the Epidemiology of Stiff Person Syndrome in a Large Colorado-Based Health System. Neurology. 2024 Dec 24;103(12):e210078. PubMed PMID: 39621949
• Lee ST, Abboud H, Irani SR, Nakajima H, Piquet AL, Pittock SJ, Yeh EA, Wang J, Rajan S, Overell J, Smith J, St Lambert J, El-Khairi M, Gafarova M, Gelfand JM. Innovation and optimization in autoimmune encephalitis trials: the design and rationale for the Phase 3, randomized study of satralizumab in patients with NMDAR-IgG-antibody-positive or LGI1-IgG-antibody-positive autoimmune encephalitis (CIELO). Front Neurol. 2024;15:1437913. PubMed PMID: 39193150
• Kammeyer R, Chapman K, Furniss A, Hsieh E, Fuhlbrigge R, Ogbu EA, Boackle S, Zell J, Nair KV, Borko TL, Cooper JC, Bennett JL, Piquet AL. Blood-based biomarkers of neuronal and glial injury in active major neuropsychiatric systemic lupus erythematosus. Lupus. 2024 Sep;33(10):1116-1129. PubMed PMID: 39148457
• Oliveira SNMCG, Bezerra FF, Piquet AA, Sales RA, Valle GCT, Capillé NV, Tovar AMF, Mourão PAS. A Unique Enoxaparin Derived from Bovine Intestinal Heparin: A Single Purification Step of the Starting Material Assures a Bovine Enoxaparin Like the Standard from Porcine Origin. ACS Omega. 2024 May 28;9(21):23111-23120. PubMed PMID: 38826523
• Kister I, Curtin R, Piquet AL, Borko T, Pei J, Banbury BL, Bacon TE, Kim A, Tuen M, Velmurugu Y, Nyovanie S, Selva S, Samanovic MI, Mulligan MJ, Patskovsky Y, Priest J, Cabatingan M, Winger RC, Krogsgaard M, Silverman GJ. Longitudinal study of immunity to SARS-CoV2 in ocrelizumab-treated MS patients up to 2?years after COVID-19 vaccination. Ann Clin Transl Neurol. 2024 Jul;11(7):1750-1764. PubMed PMID: 38713096
• Ardakani R, Chauhan L, Piquet AL, Tyler KL, Pastula DM. An Overview of Saint Louis Encephalitis. Neurohospitalist. 2024 Apr;14(2):230-231. PubMed PMID: 38666278
• Vervloet Sollero CE, Piquet AL, Robinson C, Gyang TV, Carlson A. Anti-NMDA Receptor Encephalitis Related to Renal Cell Carcinoma: A Case Report. Neurohospitalist. 2024 Apr;14(2):189-194. PubMed PMID: 38666271
• Jellins TS, Borko TL, Otero-Bell R, Arnett K, Saunders S, Poisson SN, Orjuela KD, Salehi Omran S, Jones WJ, Leppert M, Madera A, Carlson A, Pastula DM, Sauer BM, Piquet AL, Gonzales NR. Diversity, equity, and inclusion (DEI) in medical education: DEI at the bedside. J Neurol Sci. 2024 Apr 15;459:122946. PubMed PMID: 38493733
• Baxter RM, Cabrera-Martinez B, Ghosh T, Rester C, Moreno MG, Borko TL, Selva S, Fleischer CL, Haakonsen N, Mayher A, Bowhay E, Evans C, Miller TM, Huey L, McWilliams J, van Bokhoven A, Deane KD, Knight V, Jordan KR, Ghosh D, Klarquist J, Kedl RM, Piquet AL, Hsieh EWY. SARS-CoV-2 Vaccine-Elicited Immunity after B Cell Depletion in Multiple Sclerosis. Immunohorizons. 2024 Mar 1;8(3):254-268. PubMed PMID: 38483384
• Xu J, Erlendsson S, Singh M, Holling GA, Regier M, Ibiricu I, Einstein J, Hantak MP, Day GS, Piquet AL, Smith TL, Clardy SL, Whiteley AM, Feschotte C, Briggs JAG, Shepherd JD. PNMA2 forms immunogenic non-enveloped virus-like capsids associated with paraneoplastic neurological syndrome. Cell. 2024 Feb 15;187(4):831-845.e19. PubMed PMID: 38301645
• Celli SI, Nash R, Money KM, Garza M, Borko TL, Mizenko C, McMenamin C, Von Geldern G, Georges G, Piquet AL. Successful Autologous Hematopoietic Stem Cell Transplant in Glycine Receptor Antibody-Positive Stiff Person Syndrome: A Case Report. Neurol Neuroimmunol Neuroinflamm. 2024 Mar;11(2):e200197. PubMed PMID: 38170953
• Kammeyer R, Ogbu EA, Cooper JC, Stolz E, Piquet AL, Fuhlbrigge RC, Bennett JL, Hutaff-Lee C. Cognitive dysfunction in pediatric systemic lupus erythematosus: current knowledge and future directions. Child Neuropsychol. 2024 Jul;30(5):818-846. PubMed PMID: 37902575
• Lee ST, Abboud H, Irani SR, Nakajima H, Piquet AL, Pittock SJ, Yeh EA, Wang J, Rajan S, Overell J, Smith J, St Lambert J, El-Khairi M, Gafarova M, Gelfand JM. Innovation and optimization in autoimmune encephalitis trials: the design and rationale for the Phase 3, randomized study of satralizumab in patients with NMDAR-IgG-antibody-positive or LGI1-IgG-antibody-positive autoimmune encephalitis (CIELO). Front Neurol. 2024;15:1437913. PubMed PMID: 39193150
• Kammeyer R, Chapman K, Furniss A, Hsieh E, Fuhlbrigge R, Ogbu EA, Boackle S, Zell J, Nair KV, Borko TL, Cooper JC, Bennett JL, Piquet AL. Blood-based biomarkers of neuronal and glial injury in active major neuropsychiatric systemic lupus erythematosus. Lupus. 2024 Sep;33(10):1116-1129. PubMed PMID: 39148457
• Kister I, Curtin R, Piquet AL, Borko T, Pei J, Banbury BL, Bacon TE, Kim A, Tuen M, Velmurugu Y, Nyovanie S, Selva S, Samanovic MI, Mulligan MJ, Patskovsky Y, Priest J, Cabatingan M, Winger RC, Krogsgaard M, Silverman GJ. Longitudinal study of immunity to SARS-CoV2 in ocrelizumab-treated MS patients up to 2?years after COVID-19 vaccination. Ann Clin Transl Neurol. 2024 Jul;11(7):1750-1764. PubMed PMID: 38713096
• Ardakani R, Chauhan L, Piquet AL, Tyler KL, Pastula DM. An Overview of Saint Louis Encephalitis. Neurohospitalist. 2024 Apr;14(2):230-231. PubMed PMID: 38666278
• Vervloet Sollero CE, Piquet AL, Robinson C, Gyang TV, Carlson A. Anti-NMDA Receptor Encephalitis Related to Renal Cell Carcinoma: A Case Report. Neurohospitalist. 2024 Apr;14(2):189-194. PubMed PMID: 38666271
• Jellins TS, Borko TL, Otero-Bell R, Arnett K, Saunders S, Poisson SN, Orjuela KD, Salehi Omran S, Jones WJ, Leppert M, Madera A, Carlson A, Pastula DM, Sauer BM, Piquet AL, Gonzales NR. Diversity, equity, and inclusion (DEI) in medical education: DEI at the bedside. J Neurol Sci. 2024 Apr 15;459:122946. PubMed PMID: 38493733
• Baxter RM, Cabrera-Martinez B, Ghosh T, Rester C, Moreno MG, Borko TL, Selva S, Fleischer CL, Haakonsen N, Mayher A, Bowhay E, Evans C, Miller TM, Huey L, McWilliams J, van Bokhoven A, Deane KD, Knight V, Jordan KR, Ghosh D, Klarquist J, Kedl RM, Piquet AL, Hsieh EWY. SARS-CoV-2 Vaccine-Elicited Immunity after B Cell Depletion in Multiple Sclerosis. Immunohorizons. 2024 Mar 1;8(3):254-268. PubMed PMID: 38483384
• Xu J, Erlendsson S, Singh M, Holling GA, Regier M, Ibiricu I, Einstein J, Hantak MP, Day GS, Piquet AL, Smith TL, Clardy SL, Whiteley AM, Feschotte C, Briggs JAG, Shepherd JD. PNMA2 forms immunogenic non-enveloped virus-like capsids associated with paraneoplastic neurological syndrome. Cell. 2024 Feb 15;187(4):831-845.e19. PubMed PMID: 38301645
• Celli SI, Nash R, Money KM, Garza M, Borko TL, Mizenko C, McMenamin C, Von Geldern G, Georges G, Piquet AL. Successful Autologous Hematopoietic Stem Cell Transplant in Glycine Receptor Antibody-Positive Stiff Person Syndrome: A Case Report. Neurol Neuroimmunol Neuroinflamm. 2024 Mar;11(2):e200197. PubMed PMID: 38170953
• Kammeyer R, Ogbu EA, Cooper JC, Stolz E, Piquet AL, Fuhlbrigge RC, Bennett JL, Hutaff-Lee C. [Formula: see text] Cognitive dysfunction in pediatric systemic lupus erythematosus: current knowledge and future directions. Child Neuropsychol. 2024 Jul;30(5):818-846. PubMed PMID: 37902575
• Crane P, Sillau S, Dreher R, Fix R, Winters P, Van Coevering R, Engebretson E, Valdez B, Matthews E, Nair KV, Carlson AM, Piquet AL. A Population-Based Study of the Epidemiology of Stiff Person Syndrome in a Large Colorado-Based Health System. Neurology. Accepted September 2024, in press.
• Crane PD, Sillau S, Dreher R, Fix R, Winters P, Van Coevering R, Engebretson E, Valdez B, Matthews E, Nair KV, Carlson AM, Piquet AL. Population-Based Study of the Epidemiology of Stiff Person Syndrome in a Large Colorado-Based Health System. Neurology. 2024 Dec 24;103(12):e210078. PubMed PMID: 39621949
• Akkus S, Elkhooly M, Amatya S, Shrestha K, Sharma K, Kagzi Y, Khan E, Gupta R, Piquet AL, Jaiswal S, Wen S, Tapia M, Samant R, Sista SR, Sriwastava S. Autoimmune and paraneoplastic neurological disorders: A review of relevant neuroimaging findings. Journal of the Neurological Sciences. doi:10.1016/j.jns.2023.120830
• Money KM, Cronin J, Guimaraes-Young A, Carlson A, Lovell MA, Matthews E, Orjuela K, Pastula D, Wartchow, E, Piquet, AL. CADASIL progression after neurologic infectious insults: Case report of a new pathogenic NOTCH3 mutation. Neuroimmunology Reports. 2023;4:100186. doi: https://doi.org/10.1016/j.nerep.2023.100186.
• Kammeyer R, Ogbu EA, Cooper JC, Stolz, E, Piquet, AL, Fuhlbrigge, RC, Bennet JL, Hutaff-Lee, C. Cognitive dysfunction in pediatric systemic lupus erythematosus: current knowledge and future directions. Child Neuropsychology.1-29. doi:10.1080/09297049.2023.2273573
• Akkus S, Elkhooly M, Amatya S, Shrestha K, Sharma K, Kagzi Y, Khan E, Gupta R, Piquet AL, Jaiswal S, Wen S, Tapia M, Samant R, Sista SR, Sriwastava S. Autoimmune and paraneoplastic neurological disorders: A review of relevant neuroimaging findings. J Neurol Sci. 2023 Nov 15;454:120830. PubMed PMID: 37856996
• Borko TL, Baxter R, Cabrera-Martinez B, Thiruppathi E, Sabalza M, Venkataraman I, Selva S, Rester C, Sillau S, Pastula DM, Bennett JL, Alvarez E, Gross R, Shah A, Kammeyer R, Corboy JR, Kedl RM, Hsieh EWY, Piquet AL. SARS-CoV-2 mRNA vaccination induces an antigen-specific T cell response correlating with plasma interferon-gamma in B cell depleted patients. J Neuroimmunol. 2023 Oct 15;383:578192. PubMed PMID: 37666038
• Bartley CM, Ngo TT, Do LD, Zekeridou A, Dandekar R, Muñiz-Castrillo S, Alvarenga BD, Zorn KC, Tubati A, Pinto AL, Browne WD, Hullett PW, Terrelonge M, Schubert RD, Piquet AL, Yang B, Montalvo M, Kung AF, Mann SA, Shah MP, Geschwind MD, Gelfand JM, DeRisi JL, Pittock SJ, Honnorat J, Pleasure SJ, Wilson MR. Detection of High-Risk Paraneoplastic Antibodies against TRIM9 and TRIM67 Proteins. Ann Neurol. 2023 Dec;94(6):1086-1101. PubMed PMID: 37632288
• Wolf AB, Money KM, Chandnani A, Daley CL, Griffith DE, Chauhan L, Coffman N, Piquet AL, Tyler KL, Zimmer SM, Montague BT, Mann S, Pastula DM. Mycobacterium abscessus Meningitis Associated with Stem Cell Treatment During Medical Tourism. Emerg Infect Dis. 2023 Aug;29(8):1655-1658. PubMed PMID: 37486227
• Money KM, Chauhan L, Piquet AL, Tyler KL, Pastula DM. An Overview of Japanese Encephalitis. Neurohospitalist. 2023 Jul;13(3):328-330. PubMed PMID: 37441216
• Barrera B, Simpson H, Engebretson E, Sillau S, Valdez B, Parra-González J, Winger RC, Epperson LA, Banks A, Pierce K, Spotts M, O'Gean K, Alvarez E, Gross R, Piquet AL, Schreiner T, Corboy JR, Pei J, Vollmer TL, Nair KV. Safety and patient experience with at-home infusion of ocrelizumab for multiple sclerosis. Ann Clin Transl Neurol. 2023 Apr;10(4):579-588. PubMed PMID: 36811392
• Xu J, Erlendsson S, Singh M, Regier M, Ibiricu I, Day GS, Piquet AL, Clardy SL, Feschotte C, Briggs JAG, Shepherd JD. PNMA2 forms non-enveloped virus-like capsids that trigger paraneoplastic neurological syndrome. bioRxiv. 2023 Feb 9. PubMed PMID: 36798413
• Lowe MC, Money KM, Matthews E, Pastula DM, Piquet AL. case of autoimmune GFAP astrocytopathy with eosinophils in the cerebrospinal fluid. J Neuroimmunol. 2023 Dec 15;385:578249. PubMed PMID: 37992587
• Borko TL, Baxter R, Cabrera-Martinez B, Thiruppathi E, Sabalza M, Venkataraman I, Selva S, Rester C, Sillau S, Pastula DM, Bennett JL, Alvarez E, Gross R, Shah A, Kammeyer R, Corboy JR, Kedl RM, Hsieh EWY, Piquet AL. SARS-CoV-2 mRNA vaccination induces an antigen-specific T cell response correlating with plasma interferon-gamma in B cell depleted patients. J Neuroimmunol. 2023 Oct 15;383:578192. PubMed PMID: 37666038
• Bartley CM, Ngo TT, Do LD, Zekeridou A, Dandekar R, Muñiz-Castrillo S, Alvarenga BD, Zorn KC, Tubati A, Pinto AL, Browne WD, Hullett PW, Terrelonge M, Schubert RD, Piquet AL, Yang B, Montalvo M, Kung AF, Mann SA, Shah MP, Geschwind MD, Gelfand JM, DeRisi JL, Pittock SJ, Honnorat J, Pleasure SJ, Wilson MR. Detection of High-Risk Paraneoplastic Antibodies against TRIM9 and TRIM67 Proteins. Ann Neurol. 2023 Aug 26. [Epub ahead of print] PubMed PMID: 37632288
• Wolf AB, Money KM, Chandnani A, Daley CL, Griffith DE, Chauhan L, Coffman N, Piquet AL, Tyler KL, Zimmer SM, Montague BT, Mann S, Pastula DM. Mycobacterium abscessus Meningitis Associated with Stem Cell Treatment During Medical Tourism. Emerg Infect Dis. 2023 Aug;29(8):1655-1658. PubMed PMID: 37486227
• Money KM, Chauhan L, Piquet AL, Tyler KL, Pastula DM. An Overview of Japanese Encephalitis. Neurohospitalist. 2023 Jul;13(3):328-330. PubMed PMID: 37441216
• Barrera B, Simpson H, Engebretson E, Sillau S, Valdez B, Parra-González J, Winger RC, Epperson LA, Banks A, Pierce K, Spotts M, O'Gean K, Alvarez E, Gross R, Piquet AL, Schreiner T, Corboy JR, Pei J, Vollmer TL, Nair KV. Safety and patient experience with at-home infusion of ocrelizumab for multiple sclerosis. Ann Clin Transl Neurol. 2023 Apr;10(4):579-588. PubMed PMID: 36811392
• Xu J, Erlendsson S, Singh M, Regier M, Ibiricu I, Day GS, Piquet AL, Clardy SL, Feschotte C, Briggs JAG, Shepherd JD. PNMA2 forms non-enveloped virus-like capsids that trigger paraneoplastic neurological syndrome. bioRxiv. 2023 Feb 9. PubMed PMID: 36798413
• Pointon T, Ward R, Yeshokumar A, Piquet A, Schreiner T, Kammeyer R. Evaluation of multiple consensus criteria for autoimmune encephalitis and temporal analysis of symptoms in a pediatric encephalitis cohort. Front Neurol. 2022;13:952317. PubMed PMID: 36237630
• Matthews E, Beckham JD, Piquet AL, Tyler KL, Chauhan L, Pastula DM. Herpesvirus-Associated Encephalitis: an Update. Curr Trop Med Rep. 2022;9(3):92-100. PubMed PMID: 36186545
• Krett JD, Beckham JD, Tyler KL, Piquet AL, Chauhan L, Wallace CJ, Pastula DM, Kapadia RK. Neurology of Acute Viral Infections. Neurohospitalist. 2022 Oct;12(4):632-646. PubMed PMID: 36147750
• Pastula DM, Copeland MJ, Hannan MC, Rapaka S, Kitani T, Kleiner E, Showler A, Yuen C, Ferriman EM, House J, O'Brien S, Burakoff A, Gupta B, Money KM, Matthews E, Beckham JD, Chauhan L, Piquet AL, Kumar RN, Tornatore CS, Padgett K, O'Laughlin K, Mangla AT, Kumar PN, Tyler KL, O'Connor SM. Two Cases of Monkeypox-Associated Encephalomyelitis - Colorado and the District of Columbia, July-August 2022. MMWR Morb Mortal Wkly Rep. 2022 Sep 23;71(38):1212-1215. PubMed PMID: 36136957
• Chauhan L, Matthews E, Piquet AL, Henao-Martinez A, Franco-Paredes C, Tyler KL, Beckham D, Pastula DM. Nervous System Manifestations of Arboviral Infections. Curr Trop Med Rep. 2022;9(4):107-118. PubMed PMID: 36124288
• Passeri M, Matthews E, Kammeyer R, Piquet AL. Update in autoimmune and paraneoplastic myelopathies: Newly described antigen targets and antibody testing. Front Neurol. 2022;13:972143. PubMed PMID: 35968301
• Matthews E, Schmitt B, Passeri M, Mizenko C, Orjuela K, Piquet A. AMPA Receptor Encephalitis in a Patient With Metastatic Breast Cancer Receiving Palbociclib: A Case Report. Neurol Neuroimmunol Neuroinflamm. 2022 Sep;9(5). PubMed PMID: 35794024
• Matthews E, Chauhan L, Piquet AL, Tyler KL, Pastula DM. An Overview of La Crosse Virus Disease. Neurohospitalist. 2022 Jul;12(3):587-588. PubMed PMID: 35755222
• Kammeyer R, Mizenko C, Sillau S, Richie A, Owens G, Nair KV, Alvarez E, Vollmer TL, Bennett JL, Piquet AL. Evaluation of Plasma Neurofilament Light Chain Levels as a Biomarker of Neuronal Injury in the Active and Chronic Phases of Autoimmune Neurologic Disorders. Front Neurol. 2022;13:689975. PubMed PMID: 35309573
• Sloane KL, Miller JJ, Piquet A, Edlow BL, Rosenthal ES, Singhal AB. Prognostication in Acute Neurological Emergencies. J Stroke Cerebrovasc Dis. 2022 Mar;31(3):106277. PubMed PMID: 35007934
• Valencia-Sanchez C, Knight AM, Hammami MB, Guo Y, Mills JR, Kryzer TJ, Piquet AL, Amin A, Heinzelmann M, Lucchinetti CF, Lennon VA, McKeon A, Pittock SJ, Dubey D. Characterisation of TRIM46 autoantibody-associated paraneoplastic neurological syndrome. J Neurol Neurosurg Psychiatry. 2022 Feb;93(2):196-200. PubMed PMID: 34921120
• Matthews E, Beckham JD, Piquet AL, Tyler KL, Chauhan L, Pastula DM. Herpesvirus-Associated Encephalitis: an Update. Curr Trop Med Rep. 2022;9(3):92-100. PubMed PMID: 36186545
• Krett JD, Beckham JD, Tyler KL, Piquet AL, Chauhan L, Wallace CJ, Pastula DM, Kapadia RK. Neurology of Acute Viral Infections. Neurohospitalist. 2022 Oct;12(4):632-646. PubMed PMID: 36147750
• Pastula DM, Copeland MJ, Hannan MC, Rapaka S, Kitani T, Kleiner E, Showler A, Yuen C, Ferriman EM, House J, O'Brien S, Burakoff A, Gupta B, Money KM, Matthews E, Beckham JD, Chauhan L, Piquet AL, Kumar RN, Tornatore CS, Padgett K, O'Laughlin K, Mangla AT, Kumar PN, Tyler KL, O'Connor SM. Two Cases of Monkeypox-Associated Encephalomyelitis - Colorado and the District of Columbia, July-August 2022. MMWR Morb Mortal Wkly Rep. 2022 Sep 23;71(38):1212-1215. PubMed PMID: 36136957
• Chauhan L, Matthews E, Piquet AL, Henao-Martinez A, Franco-Paredes C, Tyler KL, Beckham D, Pastula DM. Nervous System Manifestations of Arboviral Infections. Curr Trop Med Rep. 2022 Sep 15;:1-12. [Epub ahead of print] PubMed PMID: 36124288
• Passeri M, Matthews E, Kammeyer R, Piquet AL. Update in autoimmune and paraneoplastic myelopathies: Newly described antigen targets and antibody testing. Front Neurol. 2022;13:972143. PubMed PMID: 35968301
• Matthews E, Schmitt B, Passeri M, Mizenko C, Orjuela K, Piquet A. AMPA Receptor Encephalitis in a Patient With Metastatic Breast Cancer Receiving Palbociclib: A Case Report. Neurol Neuroimmunol Neuroinflamm. 2022 Sep;9(5). PubMed PMID: 35794024
• Matthews E, Chauhan L, Piquet AL, Tyler KL, Pastula DM. An Overview of La Crosse Virus Disease. Neurohospitalist. 2022 Jul;12(3):587-588. PubMed PMID: 35755222
• Kammeyer R, Mizenko C, Sillau S, Richie A, Owens G, Nair KV, Alvarez E, Vollmer TL, Bennett JL, Piquet AL. Evaluation of Plasma Neurofilament Light Chain Levels as a Biomarker of Neuronal Injury in the Active and Chronic Phases of Autoimmune Neurologic Disorders. Front Neurol. 2022;13:689975. PubMed PMID: 35309573
• Sloane KL, Miller JJ, Piquet A, Edlow BL, Rosenthal ES, Singhal AB. Prognostication in Acute Neurological Emergencies. J Stroke Cerebrovasc Dis. 2022 Mar;31(3):106277. PubMed PMID: 35007934
• Valencia-Sanchez C, Knight AM, Hammami MB, Guo Y, Mills JR, Kryzer TJ, Piquet AL, Amin A, Heinzelmann M, Lucchinetti CF, Lennon VA, McKeon A, Pittock SJ, Dubey D. Characterisation of TRIM46 autoantibody-associated paraneoplastic neurological syndrome. J Neurol Neurosurg Psychiatry. 2022 Feb;93(2):196-200. PubMed PMID: 34921120
• Venkataraman, I, Heckler, I, Piquet, AL. The Testing Landscape of Autoimmune Neurological Conditions: Newly Discovered Cell Surface and Intracellular Antigens. 2022. J Clinical Chem Lab Med. 5:211.
• Garza M, Piquet AL. Update in Autoimmune Movement Disorders: Newly Described Antigen Targets in Autoimmune and Paraneoplastic Cerebellar Ataxia. Front Neurol. 2021;12:683048. PubMed PMID: 34489848
• Mizenko C, Bennett JL, Owens G, Vollmer TL, Piquet AL. A Longitudinal, Observational Analysis of Neuronal Injury Biomarkers in a Case Report of a Patient With Paraneoplastic Anti-CRMP5 Antibody-Associated Transverse Myelitis. Front Neurol. 2021;12:691509. PubMed PMID: 34349723
• Kapadia RK, Gill CM, Baca C, McMenamin C, Kannappan A, Niehaus WN, Tyler KL, Pastula DM, Piquet AL. Enterovirus A71 causing meningoencephalitis and acute flaccid myelitis in a patient receiving rituximab. J Neuroimmunol. 2021 Sep 15;358:577639. PubMed PMID: 34214953
• Coleman KJ, Chauhan L, Piquet AL, Tyler KL, Pastula DM. An Overview of Jamestown Canyon Virus Disease. Neurohospitalist. 2021 Jul;11(3):277-278. PubMed PMID: 34163560
• Piquet AL, Corboy JR, Vollmer TL. Correspondence to: Humoral immune response to COVID-19 mRNA vaccine in patients with multiple sclerosis treated with high-efficacy disease-modifying therapies. Ther Adv Neurol Disord. 2021;14:17562864211019567. PubMed PMID: 34104219
• High B, Hixon AM, Tyler KL, Piquet AL, Pelak VS. Neurology and the COVID-19 Pandemic: Gathering Data for an Informed Response. Neurol Clin Pract. 2021 Apr;11(2):e48-e63. PubMed PMID: 33842072
• Garza M, Piquet AL. Update in Autoimmune Movement Disorders: Newly Described Antigen Targets in Autoimmune and Paraneoplastic Cerebellar Ataxia. Front Neurol. 2021;12:683048. PubMed PMID: 34489848
• Mizenko C, Bennett JL, Owens G, Vollmer TL, Piquet AL. A Longitudinal, Observational Analysis of Neuronal Injury Biomarkers in a Case Report of a Patient With Paraneoplastic Anti-CRMP5 Antibody-Associated Transverse Myelitis. Front Neurol. 2021;12:691509. PubMed PMID: 34349723
• Kapadia RK, Gill CM, Baca C, McMenamin C, Kannappan A, Niehaus WN, Tyler KL, Pastula DM, Piquet AL. Enterovirus A71 causing meningoencephalitis and acute flaccid myelitis in a patient receiving rituximab. J Neuroimmunol. 2021 Sep 15;358:577639. PubMed PMID: 34214953
• Coleman KJ, Chauhan L, Piquet AL, Tyler KL, Pastula DM. An Overview of Jamestown Canyon Virus Disease. Neurohospitalist. 2021 Jul;11(3):277-278. PubMed PMID: 34163560
• Piquet AL, Corboy JR, Vollmer TL. Correspondence to: Humoral immune response to COVID-19 mRNA vaccine in patients with multiple sclerosis treated with high-efficacy disease-modifying therapies. Ther Adv Neurol Disord. 2021;14:17562864211019567. PubMed PMID: 34104219
• High B, Hixon AM, Tyler KL, Piquet AL, Pelak VS. Neurology and the COVID-19 Pandemic: Gathering Data for an Informed Response. Neurol Clin Pract. 2021 Apr;11(2):e48-e63. PubMed PMID: 33842072
• Deuel LM, Yu CH, Vaughan CL, Piquet AL. Oro-Bucco-Lingual Dyskinesia, Weight Loss, and Cognitive Decline in Anti-DPPX Antibody-Mediated Encephalitis. Mov Disord Clin Pract. 2020 Sep;7(Suppl 3):S80-S82. PubMed PMID: 33015231
• Kapadia RK, Chauhan L, Piquet AL, Tyler KL, Pastula DM. An Overview of Eastern Equine Encephalitis (EEE). Neurohospitalist. 2020 Jul;10(3):161-162. PubMed PMID: 32549937
• Kapadia RK, Ney DE, Hannan M, Farley M, Pastula DM, Piquet AL. Glial fibrillary acidic protein (GFAP) associated autoimmune meningoencephalitis in a patient receiving nivolumab. J Neuroimmunol. 2020 Jul 15;344:577259. PubMed PMID: 32416558
• Macchi ZA, Kleinschmidt-DeMasters BK, Orjuela KD, Pastula DM, Piquet AL, Baca CB. Glioblastoma as an autoimmune limbic encephalitis mimic: A case and review of the literature. J Neuroimmunol. 2020 Mar 7;342:577214. [Epub ahead of print] PubMed PMID: 32182452
• Gill CM, Kapadia RK, Beckham JD, Piquet AL, Tyler KL, Pastula DM. Usutu virus disease: a potential problem for North America?. J Neurovirol. 2020 Apr;26(2):149-154. PubMed PMID: 31858483
• Deuel, L, Yu, C. Vaughan, C, Piquet, AL. Oro-bucco-lingual dyskinesia, weight loss, and cognitive decline in anti-DPPX antibody-mediated encephalitis. Movement Disorders Clinical Practice. 2020 Sept. doi:10.1002/mdc3.13058
• High, B, Hixon, AM, Tyler, KL, Piquet, AL, Pelak, VS. Neurology and the COVID-19 Pandemic: Gathering Data for an Informed Response. Neurol Clin Pract Jul 2020. DOI: 10.1212/CPJ.0000000000000908
• Piquet, AL, Alvarez, E, Bennett, JL, Knapp, C, Sillau, S, Mizenko, C, Nair, K, Vollmer, T. A Retrospective, Cross-sectional Study Evaluating Plasma Neurofilament Light Levels in Autoimmune Neurological Disorders. American Neurological Association, Virtual meeting, October 2020.
• Kapadia RK, Chauhan L, Piquet AL, Tyler KL, Pastula DM. An Overview of Eastern Equine Encephalitis (EEE). Neurohospitalist. 2020 Jul;10(3):161-162. PubMed PMID: 32549937
• Kapadia RK, Ney DE, Hannan M, Farley M, Pastula DM, Piquet AL. Glial fibrillary acidic protein (GFAP) associated autoimmune meningoencephalitis in a patient receiving nivolumab. J Neuroimmunol. 2020 Jul 15;344:577259. PubMed PMID: 32416558
• Macchi ZA, Kleinschmidt-DeMasters BK, Orjuela KD, Pastula DM, Piquet AL, Baca CB. Glioblastoma as an autoimmune limbic encephalitis mimic: A case and review of the literature. J Neuroimmunol. 2020 Mar 7;342:577214. [Epub ahead of print] PubMed PMID: 32182452
• Gill CM, Kapadia RK, Beckham JD, Piquet AL, Tyler KL, Pastula DM. Usutu virus disease: a potential problem for North America?. J Neurovirol. 2020 Apr;26(2):149-154. PubMed PMID: 31858483
• Kammeyer R, Piquet AL. Multiple co-existing antibodies in autoimmune encephalitis: A case and review of the literature. J Neuroimmunol. 2019 Dec 15;337:577084. PubMed PMID: 31655424
• Khan M, Beckham JD, Piquet AL, Tyler KL, Pastula DM. An Overview of Powassan Virus Disease. Neurohospitalist. 2019 Oct;9(4):181-182. PubMed PMID: 31534605
• Gill CM, Beckham JD, Piquet AL, Tyler KL, Pastula DM. Five Emerging Neuroinvasive Arboviral Diseases: Cache Valley, Eastern Equine Encephalitis, Jamestown Canyon, Powassan, and Usutu. Semin Neurol. 2019 Aug;39(4):419-427. PubMed PMID: 31533182
• Piquet AL, Khan M, Warner JEA, Wicklund MP, Bennett JL, Leehey MA, Seeberger L, Schreiner TL, Paz Soldan MM, Clardy SL. Novel clinical features of glycine receptor antibody syndrome: A series of 17 cases. Neurol Neuroimmunol Neuroinflamm. 2019 Sep;6(5):e592. PubMed PMID: 31355325
• Khan M, Ney DE, Kleinschmidt-DeMasters BK, Horton L, Alvarez E, Piquet AL. CNS atypical T-cell lymphoproliferative disease following treatment with alemtuzumab. Neurol Clin Pract. 2019 Jun;9(3):273-276. PubMed PMID: 31341717
• Piquet AL, Linnoila J. Surface Antibody-Mediated Autoimmune Encephalitis . In: Neurorheumatology. Cho TA, Bhattacharyya S, Helfgott S, editors. New York: Springer Publishing Company; 2019
• Kammeyer R, Piquet AL. Multiple co-existing antibodies in autoimmune encephalitis: A case and review of the literature. J Neuroimmunol. 2019 Dec 15;337:577084. PubMed PMID: 31655424
• Khan M, Beckham JD, Piquet AL, Tyler KL, Pastula DM. An Overview of Powassan Virus Disease. Neurohospitalist. 2019 Oct;9(4):181-182. PubMed PMID: 31534605
• Gill CM, Beckham JD, Piquet AL, Tyler KL, Pastula DM. Five Emerging Neuroinvasive Arboviral Diseases: Cache Valley, Eastern Equine Encephalitis, Jamestown Canyon, Powassan, and Usutu. Semin Neurol. 2019 Aug;39(4):419-427. PubMed PMID: 31533182
• Piquet AL, Khan M, Warner JEA, Wicklund MP, Bennett JL, Leehey MA, Seeberger L, Schreiner TL, Paz Soldan MM, Clardy SL. Novel clinical features of glycine receptor antibody syndrome: A series of 17 cases. Neurol Neuroimmunol Neuroinflamm. 2019 Sep;6(5):e592. PubMed PMID: 31355325
• Khan M, Ney DE, Kleinschmidt-DeMasters BK, Horton L, Alvarez E, Piquet AL. CNS atypical T-cell lymphoproliferative disease following treatment with alemtuzumab. Neurol Clin Pract. 2019 Jun;9(3):273-276. PubMed PMID: 31341717
• López-Chiriboga AS, Klein C, Zekeridou A, McKeon A, Dubey D, Flanagan EP, Lennon VA, Tillema JM, Wirrell EC, Patterson MC, Gadoth A, Aaen JG, Brenton JN, Bui JD, Moen A, Otten C, Piquet A, Pittock SJ. LGI1 and CASPR2 neurological autoimmunity in children. Ann Neurol. 2018 Sep;84(3):473-480. PubMed PMID: 30076629
• Piquet AL, Clardy SL. Infection, Immunodeficiency, and Inflammatory Diseases in Autoimmune Neurology. Semin Neurol. 2018 Jun;38(3):379-391. PubMed PMID: 30011417
• López-Chiriboga AS, Klein C, Zekeridou A, McKeon A, Dubey D, Flanagan EP, Lennon VA, Tillema JM, Wirrell EC, Patterson MC, Gadoth A, Aaen JG, Brenton JN, Bui JD, Moen A, Otten C, Piquet A, Pittock SJ. LGI1 and CASPR2 neurological autoimmunity in children. Ann Neurol. 2018 Sep;84(3):473-480. PubMed PMID: 30076629
• Piquet, AL. and Corboy, JR. “Neuromyelitis Optica” in Multiple Sclerosis and Related Diseases. Second ed. Fox R, Bethoux F, Rae-Grant A, editors. New York: Springer Publishing Company; 2018.
• Piquet AL, Clardy SL. Infection, Immunodeficiency, and Inflammatory Diseases in Autoimmune Neurology. Semin Neurol. 2018 Jun;38(3):379-391. PubMed PMID: 30011417
• Piquet AL. Varicella-zoster virus infections of the nervous system. In: Greenlee JT, editor-in-chief. MedLink Neurology. San Diego: MedLink Corporation. Available at www.medlink.com. First updated: June 2017. Last updated: March 2018.
• Piquet, AL. Khan, M. Warner. J, Wicklund, MP. Leehey, MA. Schreiner, T. Paz Soldan, MM. Clardy, SL. Clinical Features of Glycine Receptor Antibody Syndrome: A Series of Eleven Cases. Abstract accepted to American Neurological Association Annual Meeting, Atlanta, October 2018.
• Akbik F, Matiello M, Piquet A, Cho T, Cohen A, Venna N. Bibrachial plegia due to Lyme radiculopoliomyelitis-myelitis. J Neurol Sci. 2017 Jul 15;378:1-2. PubMed PMID: 28566141
• Khan, M. and Piquet, AL. Differential diagnosis of Meningitis and Encephalitis, article in Neurology Times. October 24, 2017.
• Galli J, Clardy SL, Piquet AL. NMDAR Encephalitis Following Herpes Simplex Virus Encephalitis. Curr Infect Dis Rep. 2017 Jan;19(1):1. PubMed PMID: 28102519
• Piquet AL. Varicella-zoster virus infections of the nervous system. In: Greenlee JT, editor-in-chief. MedLink Neurology. San Diego: MedLink Corporation. Available at www.medlink.com. Last updated: June 2017.
• Khan, M. and Piquet, AL. Differential diagnosis of Meningitis and Encephalitis, article in Neurology Times. October 24, 2017
• Piquet, AL. Hanak, T. Sweeney, M. Kaplan, V. Gundlapalli A, McKeon, A. Clardy, SL. CVID-associated Granulomatous Disease with Cervical Dystonia Mimicking Neurosarcoidosis. American Neurological Association Annual Meeting, San Diego, October 2017
• Piquet, AL. Baldassari, L. Paz-Soldan, MM. Highly active relapsing remitting multiple sclerosis following hematopoietic stem cell transplantation: a case report. American Academy of Neurology Annual Meeting, Boston, April 2017.
• Piquet, AL. Clardy, SL. Prodromal Stiffperson Syndrome: Two cases of antibody detection over a decade after symptom onset. American Academy of Neurology Annual Meeting, Boston, April 2017.
• Baldassari, L. Piquet, AL. Paz-Soldan, MM. Thalamic germinoma masquerading as CNS inflammatory disease: a case report. American Academy of Neurology Annual Meeting, Boston, April 2017.
• Patel, VD. Piquet, AL. Schlaberg, R. Greenlee, JE. Ansari, S. Clardy, SL. Next Generation Sequencing to Diagnose West Nile Encephalitis in an Immunocompromised Patient. American Academy of Neurology Annual Meeting, Boston, April 2017.
• Galli J, Clardy SL, Piquet AL. NMDAR Encephalitis Following Herpes Simplex Virus Encephalitis. Curr Infect Dis Rep. 2017 Jan;19(1):1. PubMed PMID: 28102519
• Piquet AL, Lyons JL. Infectious Meningitis and Encephalitis. Semin Neurol. 2016 Aug;36(4):367-72. PubMed PMID: 27643906
• Piquet AL, Cho TA. The Clinical Approach to Encephalitis. Curr Neurol Neurosci Rep. 2016 May;16(5):45. PubMed PMID: 27021774
• Venkiteswaran K, Alexander DN, Puhl MD, Rao A, Piquet AL, Nyland JE, Subramanian MP, Iyer P, Boisvert MM, Handly E, Subramanian T, Grigson PS. Transplantation of human retinal pigment epithelial cells in the nucleus accumbens of cocaine self-administering rats provides protection from seeking. Brain Res Bull. 2016 May;123:53-60. PubMed PMID: 26562520
• Piquet AL , Cho T. “Central Nervous System Vasculitis” in Pocket Neurology, ed. Westover MB, Bianchi MT, Choi E, Awad KM, Lippincott Williams & Wilkins. (2015).
• Piquet AL, Venkiteswaran K, Marupudi NI, Berk M, Subramanian T. The immunological challenges of cell transplantation for the treatment of Parkinson's disease. Brain Res Bull. 2012 Jul 1;88(4):320-31. PubMed PMID: 22521427
• Pagán OR, Rowlands AL, Azam M, Urban KR, Bidja AH, Roy DM, Feeney RB, Afshari LK. Reversal of cocaine-induced planarian behavior by parthenolide and related sesquiterpene lactones. Pharmacol Biochem Behav. 2008 Apr;89(2):160-70. PubMed PMID: 18222535
• Rowlands AL, Pagán OR. Parthenolide prevents the expression of cocaine-induced withdrawal behavior in planarians. Eur J Pharmacol. 2008 Mar 31;583(1):170-2. PubMed PMID: 18275955
• Piquet, AL. and Clardy, SL. “Infection, Immunodeficiency and Inflammatory disease associated with Autoimmune Neurologic Conditions” in Seminars in Neurology on Autoimmune Neurology. (Submitted, under review).
• Piquet, AL. and Corboy, JR. “Neuromyelitis Optica” in Multiple Sclerosis and Related Diseases. (Accepted, in press).
• Piquet, AL. and Linnoila, J. “Neuronal Surface Antibody-Mediated Autoimmune Encephalitis” in Neurorheumatology: A Comprehensive Guide to Immune Mediated Disorders of the Nervous System. (Accepted, in press)
• Piquet, AL. and Linnoila, J. “Neuronal Surface Antibody-Mediated Autoimmune Encephalitis” in Neurorheumatology: A Comprehensive Guide to Immune Mediated Disorders of the Nervous System. (Accepted, in press for 2019)

Professional Memberships

• American Academy of Neurology (AAN), Member
• American Neurological Association, Member
• Alpha Omega Alpha Medical Society, Member

Practice Locations

• University of Colorado Hospital
• Children's Hospital Colorado

Specialty Information

• Neurology, Board Certification
• Neuroimmunology

• Immune System - Autoimmune Disorders
• Immune System
• Brain and Nervous System - Multiple Sclerosis
• Brain and Nervous System
• Brain and Nervous System - Autoimmune encephalitis and myelitis
• Brain and Nervous System - CNS Vasculitis
• Brain and Nervous System - Encephalitis
• Brain and Nervous System - Meningitis
• Brain and Nervous System - Myelin Oligodendrocyte Antibody Disease (MOGAD)
• Brain and Nervous System - Neuromyelitis optica (NMO)
• Brain and Nervous System - Neurosarcoidosis
• Brain and Nervous System - Paraneoplastic Neurological Disorders
• Brain and Nervous System - Stiff Person Syndrome