David Higgins, MD, MS, FAAP
Instructor/Fellow, Pediatrics-Emergency Medicine

Medical School:
  • MD, University of Colorado Denver School of Medicine (2013)
Graduate School :
  • MS, Colorado State University (2009)
Undergraduate School:
  • BS, Colorado State University (CO) (2006)
  • University of Washington Program (2014)
  • University of Washington Program, Pediatrics (2016)
Languages: English
Department: Pediatrics-Emergency Medicine

Professional Titles

  • Clinical Instructor


  • Higgins D, Otero J, Jefferis Kirk C, Pak J, Jorgensen N, Kemna M, Albers E, Hong B, Friedland-Little J, Law Y. Iron Laboratory Studies in Pediatric Patients With Heart Failure from Dilated Cardiomyopathy. Am J Cardiol. 2017 Dec 1;120(11):2049-2055. PubMed PMID: 28942941
  • Chan KH, Liang C, Wilson P, Higgins D, Allen GC. Long-term safety and efficacy data on botulinum toxin type A: an injection for sialorrhea. JAMA Otolaryngol Head Neck Surg. 2013 Feb;139(2):134-8. PubMed PMID: 23429943
  • Wilson J, Higgins D, Hutting H, Serkova N, Baird C, Khailova L, Queensland K, Vu Tran Z, Weitzel L, Wischmeyer PE. Early propranolol treatment induces lung heme-oxygenase-1, attenuates metabolic dysfunction, and improves survival following experimental sepsis. Crit Care. 2013 Sep 10;17(5):R195. PubMed PMID: 24020447
  • Higgins DM, Wischmeyer PE, Queensland KM, Sillau SH, Sufit AJ, Heyland DK. Relationship of vitamin D deficiency to clinical outcomes in critically ill patients. JPEN J Parenter Enteral Nutr. 2012 Nov;36(6):713-20. PubMed PMID: 22523178
  • Redente EF, Higgins DM, Dwyer-Nield LD, Orme IM, Gonzalez-Juarrero M, Malkinson AM. Differential polarization of alveolar macrophages and bone marrow-derived monocytes following chemically and pathogen-induced chronic lung inflammation. J Leukoc Biol. 2010 Jul;88(1):159-68. PubMed PMID: 20360403
  • Early MA, Lishnevsky M, Gilchrist JM, Higgins DM, Orme IM, Muller WA, Gonzalez-Juarerro M, Schenkel AR. Non-invasive diagnosis of early pulmonary disease in PECAM-deficient mice using infrared pulse oximetry. Exp Mol Pathol. 2009 Oct;87(2):152-8. PubMed PMID: 19646434
  • Higgins DM, Sanchez-Campillo J, Rosas-Taraco AG, Lee EJ, Orme IM, Gonzalez-Juarrero M. Lack of IL-10 alters inflammatory and immune responses during pulmonary Mycobacterium tuberculosis infection. Tuberculosis (Edinb). 2009 Mar;89(2):149-57. PubMed PMID: 19213603
  • Higgins DM, Basaraba RJ, Hohnbaum AC, Lee EJ, Grainger DW, Gonzalez-Juarrero M. Localized immunosuppressive environment in the foreign body response to implanted biomaterials. Am J Pathol. 2009 Jul;175(1):161-70. PubMed PMID: 19528351
  • Rosas-Taraco AG, Higgins DM, Sánchez-Campillo J, Lee EJ, Orme IM, González-Juarrero M. Intrapulmonary delivery of XCL1-targeting small interfering RNA in mice chronically infected with Mycobacterium tuberculosis. Am J Respir Cell Mol Biol. 2009 Aug;41(2):136-45. PubMed PMID: 19097989
  • Higgins DM, Sanchez-Campillo J, Rosas-Taraco AG, Higgins JR, Lee EJ, Orme IM, Gonzalez-Juarrero M. Relative levels of M-CSF and GM-CSF influence the specific generation of macrophage populations during infection with Mycobacterium tuberculosis. J Immunol. 2008 Apr 1;180(7):4892-900. PubMed PMID: 18354213
  • Ordway D, Higgins DM, Sanchez-Campillo J, Spencer JS, Henao-Tamayo M, Harton M, Orme IM, Gonzalez Juarrero M. XCL1 (lymphotactin) chemokine produced by activated CD8 T cells during the chronic stage of infection with Mycobacterium tuberculosis negatively affects production of IFN-gamma by CD4 T cells and participates in granuloma stability. J Leukoc Biol. 2007 Nov;82(5):1221-9. PubMed PMID: 17699612
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Practice Locations

Children's Hospital Colorado Anschutz Medical Campus
13123 East 16th Ave
Aurora, CO 80045

Hospital Affiliation
  • Children's Hospital Colorado

Specialty Information

  • Pediatrics, Board Certification (2016)
Public Speaking

General Information

Medical Schools:
  • MD, University of Colorado Denver School of Medicine (2013)
Graduate Schools:
  • MS, Colorado State University (2009)
Undergraduate Schools:
  • BS, Colorado State University (CO) (2006)
  • University of Washington Program (2014)
Residency Programs:
  • University of Washington Program, Pediatrics (2016)
Languages: English
Department: Pediatrics-Emergency Medicine
Contact Us
CU Anschutz
Fitzsimons Building

13001 East 17th Place
Campus Box C290
Aurora, CO 80045

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