Sean Iwamoto, MD

Professional Titles

• Assistant Professor of Medicine

Recognitions

• “I CARE” (Integrity, Commitment, Advocacy, Respect, and Excellence) Certificate of Commitment, Veterans Health Administration (2023)
  Commitment related to transgender healthcare for veterans.
• Coin of Recognition, Denis R. McDonough, U.S. Secretary of Veterans Affairs (2022)
  In recognition of gender-affirming healthcare at the VA.
• “I CARE” (Integrity, Commitment, Advocacy, Respect, and Excellence) Certificate of Advocacy, Veterans Health Administration (2022)
  Advocacy related to transgender healthcare for veterans.
• Medical Staff Award for Excellence in Clinical Innovation, University of Colorado Hospital (2019)
  UCHealth Integrated Transgender Program: Alaniz V, Burgamy S, Chavez A, Carter D, Davies R, Frasca K, French B, Huguelet P, Iwamoto S, Lee R, Rothman M, Bregman J, Spongberg E and Fisher K
• Presidential Poster Competition Winner (Obesity, Adiposity and Appetite), Endocrine Society (2019)
  Age-related differences in appetite regulation among adults with obesity: More than just hunger and PYY and Ghrelin? Oh My!
• Ally Award, One Colorado (2019)
  As part of the UCHealth Integrated Transgender Program

Publications

• Harrison DJ, Prada F, Nokoff NJ, Iwamoto SJ, Pastor T, Jacobsen RM, Yeung E. Considerations for Gender-Affirming Hormonal and Surgical Care Among Transgender and Gender Diverse Adolescents and Adults With Congenital Heart Disease. J Am Heart Assoc. 2024 Feb 6;13(3):e031004. PubMed PMID: 38293963
• Iwamoto SJ, Rothman MS, T'Sjoen G, Defreyne J. Approach to the Patient: Hormonal Therapy in Transgender Adults With Complex Medical Histories. J Clin Endocrinol Metab. 2024 Jan 18;109(2):592-602. PubMed PMID: 37683089
• Hoffner-Heinike A, Iwamoto SJ, Saxon DR, Cogdall NA, Davies RD, Lee RS, Chiappone A, Thomas JF, Rothman MS. ECHO "Bootcamp": An Innovative Training Model to Onboard Providers in the Care of Gender Diverse Patients. Telemed J E Health. 2024 Feb;30(2):430-437. PubMed PMID: 37499094
• Iwamoto SJ, Rothman MS, T'Sjoen G, Defreyne J. Approach to the Patient: Hormonal Therapy in Transgender Adults With Complex Medical Histories. J Clin Endocrinol Metab. 2024 Jan 18;109(2):592-602. PubMed PMID: 37683089
• Harrison DJ, Prada F, Nokoff NJ, Iwamoto SJ, Pastor T, Jacobsen RM, Yeung E. Considerations for Gender-Affirming Hormonal and Surgical Care Among Transgender and Gender Diverse Adolescents and Adults With Congenital Heart Disease. J Am Heart Assoc. 2024 Feb 6;13(3):e031004. PubMed PMID: 38293963
• Taormina JM, Cordoba Kissee M, Brownstone LM, Grimstad F, Morrison SD, Hendrixson A, Iwamoto SJ. Approach to the Patient: Navigating Body Mass Index Requirements for Gender-Affirming Surgery. J Clin Endocrinol Metab. 2024 Aug 13;109(9):2389-2399. PubMed PMID: 38584330
• Iwamoto SJ, Rice JD, Moreau KL, Cornier MA, Wierman ME, Mancuso MP, Gebregzabheir A, Hammond DB, Rothman MS. The association of gender-affirming hormone therapy duration and body mass index on bone mineral density in gender diverse adults. J Clin Transl Endocrinol. 2024 Jun;36:100348. PubMed PMID: 38756206
• Rothman MS, Ariel D, Kelley C, Hamnvik OR, Abramowitz J, Irwig MS, Soe K, Davidge-Pitts C, Misakian AL, Safer JD, Iwamoto SJ. The Use of Injectable Estradiol in Transgender and Gender Diverse Adults: A Scoping Review of Dose and Serum Estradiol Levels. Endocr Pract. 2024 Sep;30(9):870-878. PubMed PMID: 38782202
• Iwamoto SJ, Moreau KL. Exercise and Sport Sciences Reviews: 2023 Paper of the Year. Exerc Sport Sci Rev. 2024 Oct 1;52(4):115-116. PubMed PMID: 39248634
• Rothman MS, Hamnvik OR, Davidge-Pitts C, Safer JD, Ariel D, Tangpricha V, Abramowitz J, Soe K, Sarvaideo J, Kelley C, Irwig MS, Iwamoto SJ. Revisiting Injectable Estrogen Dosing Recommendations for Gender-Affirming Hormone Therapy. Transgend Health. 2024 Dec;9(6):463-465. PubMed PMID: 39735380
• Hoffner-Heinike A, Iwamoto SJ, Saxon DR, Cogdall NA, Davies RD, Lee RS, Chiappone A, Thomas JF, Rothman MS. ECHO "Bootcamp": An Innovative Training Model to Onboard Providers in the Care of Gender Diverse Patients. Telemed J E Health. 2023 Jul 27. [Epub ahead of print] PubMed PMID: 37499094
• Taormina JM, Gilden AH, Iwamoto SJ. Meeting the Body Mass Index Requirement for Gender-affirming Surgery Using Antiobesity Medication. JCEM Case Rep. 2023 May;1(3):luad067. PubMed PMID: 37388627
• Iwamoto SJ, Defreyne J, Kaoutzanis C, Davies RD, Moreau KL, Rothman MS. Gender-affirming hormone therapy, mental health, and surgical considerations for aging transgender and gender diverse adults. Ther Adv Endocrinol Metab. 2023;14:20420188231166494. PubMed PMID: 37113210
• Defreyne J, Vander Stichele C, Iwamoto SJ, T'Sjoen G. Gender-affirming hormonal therapy for transgender and gender-diverse people-A narrative review. Best Pract Res Clin Obstet Gynaecol. 2023 Feb;86:102296. PubMed PMID: 36596713
• Pribish AM, Iwamoto SJ. Cardiovascular disease and feminizing gender-affirming hormone therapy: Implications for the provision of safe and lifesaving care. Curr Opin Physiol. 2023 Jun;33. PubMed PMID: 36968433
• Iwamoto SJ, Defreyne J, Kaoutzanis C, Davies RD, Moreau KL, Rothman MS. Gender-affirming hormone therapy, mental health, and surgical considerations for aging transgender and gender diverse adults. Ther Adv Endocrinol Metab. 2023;14:20420188231166494. PubMed PMID: 37113210
• Taormina JM, Gilden AH, Iwamoto SJ. Meeting the Body Mass Index Requirement for Gender-affirming Surgery Using Antiobesity Medication. JCEM Case Rep. 2023 May;1(3):luad067. PubMed PMID: 37388627
• Taormina JM, Iwamoto SJ. Filling a gap in care: addressing obesity in transgender and gender diverse patients. Int J Obes (Lond). 2023 Sep;47(9):761-763. PubMed PMID: 37414875
• Hoffner-Heinike A, Iwamoto SJ, Saxon DR, Cogdall NA, Davies RD, Lee RS, Chiappone A, Thomas JF, Rothman MS. ECHO "Bootcamp": An Innovative Training Model to Onboard Providers in the Care of Gender Diverse Patients. Telemed J E Health. 2023 Jul 27. [Epub ahead of print] PubMed PMID: 37499094
• Defreyne J, Vander Stichele C, Iwamoto SJ, T'Sjoen G. Gender-affirming hormonal therapy for transgender and gender-diverse people-A narrative review. Best Pract Res Clin Obstet Gynaecol. 2023 Feb;86:102296. PubMed PMID: 36596713
• Pribish AM, Iwamoto SJ. Cardiovascular disease and feminizing gender-affirming hormone therapy: Implications for the provision of safe and lifesaving care. Curr Opin Physiol. 2023 Jun;33. PubMed PMID: 36968433
• Taormina JM, Iwamoto SJ. Filling a gap in care: addressing obesity in transgender and gender diverse patients. Int J Obes (Lond). 2023 Sep;47(9):761-763. PubMed PMID: 37414875
• Sotiros AR, Iwamoto SJ, Rothman MS, Lee RS. A Novel Multidisciplinary Model of Care for Transgender and Gender Diverse Adults: Program Description and Patient Perspectives. Transgend Health. 2022 Jun;7(3):276-281. PubMed PMID: 36643065
• Walch A, Davidge-Pitts C, Lopez X, Tangpricha V, Iwamoto SJ, Safer JD. Response to Letter to the Editor from Malone: "Proper Care of Transgender and Gender Diverse Persons in the Setting of Proposed Discrimination: A Policy Perspective". J Clin Endocrinol Metab. 2021 Jul 13;106(8):e3295-e3296. PubMed PMID: 33772302
• Iwamoto SJ, Grimstad F, Irwig MS, Rothman MS. Routine Screening for Transgender and Gender Diverse Adults Taking Gender-Affirming Hormone Therapy: a Narrative Review. J Gen Intern Med. 2021 May;36(5):1380-1389. PubMed PMID: 33547576
• Iwamoto SJ, Abushamat LA, Zaman A, Millard AJ, Cornier MA. Obesity Management in Cardiometabolic Disease: State of the Art. Curr Atheroscler Rep. 2021 Aug 4;23(10):59. PubMed PMID: 34345933
• Walch A, Davidge-Pitts C, Safer JD, Lopez X, Tangpricha V, Iwamoto SJ. Proper Care of Transgender and Gender Diverse Persons in the Setting of Proposed Discrimination: A Policy Perspective. J Clin Endocrinol Metab. 2021 Jan 23;106(2):305-308. PubMed PMID: 33326028
• Iwamoto SJ, Rothman MS, Duan S, Baker JC, Mumm S, Whyte MP. Early-onset Paget's disease of bone in a Mexican family caused by a novel tandem duplication (77dup27) in TNFRSF11A that encodes RANK. Bone. 2020 Apr;133:115224. PubMed PMID: 31923705
• Defreyne J, Vanwonterghem Y, Collet S, Iwamoto SJ, Wiepjes CM, Fisher AD, Schreiner T, Heijer MD, T'Sjoen G. Vaginal bleeding and spotting in transgender men after initiation of testosterone therapy: A prospective cohort study (ENIGI). Int J Transgend Health. 2020 Feb 12;21(2):163-175. PubMed PMID: 32935087
• Iwamoto SJ, T'Sjoen G, Safer JD, Davidge-Pitts CJ, Wierman ME, Glodowski MB, Rothman MS. Letter to the Editor: "Progesterone Is Important for Transgender Women's Therapy-Applying Evidence for the Benefits of Progesterone in Ciswomen". J Clin Endocrinol Metab. 2019 Aug 1;104(8):3127-3128. PubMed PMID: 30860591
• Rothman MS, Iwamoto SJ. Bone Health in the Transgender Population. Clin Rev Bone Miner Metab. 2019 Jun;17(2):77-85. PubMed PMID: 31452648
• Saxon DR, Chaussee EL, Juarez-Colunga E, Tsai AG, Iwamoto SJ, Speer RB, Heyn H, Kealey EH, Bessesen DH. A Toolbox Approach to Obesity Treatment in Urban Safety-Net Primary Care Clinics: a Pragmatic Clinical Trial. J Gen Intern Med. 2019 Nov;34(11):2405-2413. PubMed PMID: 31485965
• Iwamoto SJ, Defreyne J, Rothman MS, Van Schuylenbergh J, Van de Bruaene L, Motmans J, T'Sjoen G. Health considerations for transgender women and remaining unknowns: a narrative review. Ther Adv Endocrinol Metab. 2019;10:2042018819871166. PubMed PMID: 31516689
• Saxon DR, Iwamoto SJ, Mettenbrink CJ, McCormick E, Arterburn D, Daley MF, Oshiro CE, Koebnick C, Horberg M, Young DR, Bessesen DH. Antiobesity Medication Use in 2.2 Million Adults Across Eight Large Health Care Organizations: 2009-2015. Obesity (Silver Spring). 2019 Dec;27(12):1975-1981. PubMed PMID: 31603630
• Moreau KL, Iwamoto SJ, Runchey S. Aging and endocrinology. In: McDermott MT, editor. Endocrine Secrets 7. St. Louis, MO: Elsevier, Inc; 2020. p. 473-486.
• Rothman MS, Iwamoto SJ. Gender-affirming treatment for adults with gender incongruence and gender dysphoria. In: McDermott MT, editor. Endocrine Secrets 7. St. Louis, MO: Elsevier, Inc; 2020. p. 438-445.
• Iwamoto SJ, Cornier MA. Help, my metabolism is low! In: McDermott MT, editor. Management of patients with pseudo-endocrine disorders. Cham, Switzerland: Springer Nature Switzerland AG. 2019. p. 77-90.
• Iwamoto S, Saxon D, Tsai A, Leister E, Speer R, Heyn H, Kealey E, Juarez-Colunga E, Gudzune K, Bleich S, Clark J, Bessesen D. Effects of Education and Experience on Primary Care Providers' Perspectives of Obesity Treatments during a Pragmatic Trial. Obesity (Silver Spring). 2018 Oct;26(10):1532-1538. PubMed PMID: 30257072
• Nilsen J, Chen S, Irwin RW, Iwamoto S, Brinton RD. Estrogen protects neuronal cells from amyloid beta-induced apoptosis via regulation of mitochondrial proteins and function. BMC Neurosci. 2006 Nov 3;7:74. PubMed PMID: 17083736

Professional Memberships

• Endocrine Society, Member
• American Association of Clinical Endocrinologists, Member
• World Professional Association for Transgender Health, Member
• U.S. Professional Association for Transgender Health, Member
• Colorado Society for Endocrinology and Metabolism, Member
• GLMA Health Professionals Advancing LGBTQ Equality, Member

Practice Locations

UCHealth Diabetes and Endocrinology Clinic - Anschutz Medical Campus
1635 Aurora Ct
6th Floor
Aurora, CO 80045
720-848-2650

Rocky Mountain Regional Veterans Administration Medical Center
1700 Wheeling St
Aurora, CO 80045
303-399-8020

Hospital Affiliation

• University of Colorado Hospital
• Veterans Affairs Medical Center

Center Affiliations

• Colorado Clinical & Translational Sciences Institute (CCTSI)
• Anschutz Health & Wellness Center
• Center for Women's Health Research
• Nutrition Obesity Research Center

Specialty Information

Specialties

• Endocrinology, Diabetes and Metabolism, Board Certification (2017, 2017)
• Internal Medicine, Board Certification (2014, 2014)
• Pharmacogenomics Certificate Program, Certificate (2020)
• Equity Certificate Program - Office of Diversity, Equity, Inclusion & Community Engagement, Certificate (2021)

Conditions & Treatments

• Endocrine System (Hormones) - Adrenal Diseases
• Endocrine System (Hormones)
• Endocrine System (Hormones) - Adult Type 1 Diabetes
• Endocrine System (Hormones) - Adult Type 2 Diabetes
• Endocrine System (Hormones) - Endocrine Cancer (Parathyroid, Adrenal, Carcinoid)
• Endocrine System (Hormones) - Lipidosis
• Endocrine System (Hormones) - Osteoporosis
• Endocrine System (Hormones) - Thyroid Cancer
• Endocrine System (Hormones) - Thyroid Disease
• Transgender Health for Adults
• Food, Nutrition and Metabolism - Obesity
• Food, Nutrition and Metabolism