Sean Iwamoto, MD
Assistant Professor, Medicine-Endocrinology/Metabolism/Diabetes

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Medical School:
  • MD, University of Rochester School of Medicine and Dentistry (2011)
Undergraduate School:
  • BA, Claremont McKenna College (2003)
Internship:
  • California Pacific Medical Center Program (2012)
Residency:
  • California Pacific Medical Center Program, Chief Resident, Internal Medicine (2015)
Fellowships:
  • University of Colorado, Endocrinology, Diabetes and Metabolism (2017)
  • Denver Veterans Affairs Medical Center, Advanced Fellowship in Geriatrics (Geriatric Research, Education and Clinical Center) (2020)
Languages: English
Department: Medicine-Endocrinology/Metabolism/Diabetes

Professional Titles

  • Assistant Professor of Medicine

Recognition & Awards

  • Coin of Recognition, Denis R. McDonough, U.S. Secretary of Veterans Affairs (2022)
    In recognition of gender-affirming healthcare at the VA.
  • “I CARE” (Integrity, Commitment, Advocacy, Respect, and Excellence) Certificate of Advocacy, Veterans Health Administration (2022)
    Advocacy related to transgender healthcare.
  • Medical Staff Award for Excellence in Clinical Innovation, University of Colorado Hospital (2019)
    UCHealth Integrated Transgender Program: Alaniz V, Burgamy S, Chavez A, Carter D, Davies R, Frasca K, French B, Huguelet P, Iwamoto S, Lee R, Rothman M, Bregman J, Spongberg E and Fisher K
  • Presidential Poster Competition Winner (Obesity, Adiposity and Appetite), Endocrine Society (2019)
    Age-related differences in appetite regulation among adults with obesity: More than just hunger and PYY and Ghrelin? Oh My!
  • Ally Award, One Colorado (2019)
    As part of the UCHealth Integrated Transgender Program
  • Highest Impact Paper by a Trainee-MD Fellow, CUSOM Division of Endocrinology, Metabolism & Diabetes (2018)
    Iwamoto S, Saxon D, Tsai A, Leister E, Speer R, Heyn H, Kealey E, Juarez-Colunga E, Gudzune K, Bleich S, Clark J, Bessesen D. Effects of education and experience on primary care providers’ perspectives of obesity treatment during a pragmatic trial. Obesity. 2018 Oct; 26(10):1532-1538. [PMID: 30257072]
  • Presidential Poster Competition Winner (Obesity, Adiposity and Appetite), The Endocrine Society (2017)
    Weight loss correlates with improved obesity-specific and general health-related quality of life in a pragmatic obesity treatment trial within the primary care setting.
  • Clinical Fellows Abstract Award in Bone, The Endocrine Society and Shire (2017)
    High-turnover bone disease due to a novel 27-base pair tandem duplication in TNFRSF11A leading to constitutively active RANK.
  • The Obesity Society Ethan Sims Young Investigator Award Finalits, The Obesity Society (2017)
    Weight loss habits, provider discussions, and desired information: Survey of 2,811 adults with obesity.
  • Outstanding Trainee-M.D. Fellow, CUSOM Division of Endocrinology, Metabolism & Diabetes (2017)
  • University of Colorado President's Fund for Development and Support, University of Colorado (2017)
  • Outstanding M.D. Instructor/Fellow, Colorado Nutrition Obesity Research Center (2017)

Publications

  • Defreyne J, Vander Stichele C, Iwamoto SJ, T'Sjoen G. Gender-affirming hormonal therapy for transgender and gender-diverse people-A narrative review. Best Pract Res Clin Obstet Gynaecol. 2023 Feb;86:102296. PubMed PMID: 36596713
  • Sotiros AR, Iwamoto SJ, Rothman MS, Lee RS. A Novel Multidisciplinary Model of Care for Transgender and Gender Diverse Adults: Program Description and Patient Perspectives. Transgend Health. 2022 Jun;7(3):276-281. PubMed PMID: 36643065
  • Walch A, Davidge-Pitts C, Lopez X, Tangpricha V, Iwamoto SJ, Safer JD. Response to Letter to the Editor from Malone: "Proper Care of Transgender and Gender Diverse Persons in the Setting of Proposed Discrimination: A Policy Perspective". J Clin Endocrinol Metab. 2021 Jul 13;106(8):e3295-e3296. PubMed PMID: 33772302
  • Iwamoto SJ, Grimstad F, Irwig MS, Rothman MS. Routine Screening for Transgender and Gender Diverse Adults Taking Gender-Affirming Hormone Therapy: a Narrative Review. J Gen Intern Med. 2021 May;36(5):1380-1389. PubMed PMID: 33547576
  • Iwamoto SJ, Abushamat LA, Zaman A, Millard AJ, Cornier MA. Obesity Management in Cardiometabolic Disease: State of the Art. Curr Atheroscler Rep. 2021 Aug 4;23(10):59. PubMed PMID: 34345933
  • Walch A, Davidge-Pitts C, Safer JD, Lopez X, Tangpricha V, Iwamoto SJ. Proper Care of Transgender and Gender Diverse Persons in the Setting of Proposed Discrimination: A Policy Perspective. J Clin Endocrinol Metab. 2021 Jan 23;106(2):305-308. PubMed PMID: 33326028
  • Iwamoto SJ, Rothman MS, Duan S, Baker JC, Mumm S, Whyte MP. Early-onset Paget's disease of bone in a Mexican family caused by a novel tandem duplication (77dup27) in TNFRSF11A that encodes RANK. Bone. 2020 Apr;133:115224. PubMed PMID: 31923705
  • Defreyne J, Vanwonterghem Y, Collet S, Iwamoto SJ, Wiepjes CM, Fisher AD, Schreiner T, Heijer MD, T'Sjoen G. Vaginal bleeding and spotting in transgender men after initiation of testosterone therapy: A prospective cohort study (ENIGI). Int J Transgend Health. 2020 Feb 12;21(2):163-175. PubMed PMID: 32935087
  • Iwamoto SJ, T'Sjoen G, Safer JD, Davidge-Pitts CJ, Wierman ME, Glodowski MB, Rothman MS. Letter to the Editor: "Progesterone Is Important for Transgender Women's Therapy-Applying Evidence for the Benefits of Progesterone in Ciswomen". J Clin Endocrinol Metab. 2019 Aug 1;104(8):3127-3128. PubMed PMID: 30860591
  • Rothman MS, Iwamoto SJ. Bone Health in the Transgender Population. Clin Rev Bone Miner Metab. 2019 Jun;17(2):77-85. PubMed PMID: 31452648
  • Saxon DR, Chaussee EL, Juarez-Colunga E, Tsai AG, Iwamoto SJ, Speer RB, Heyn H, Kealey EH, Bessesen DH. A Toolbox Approach to Obesity Treatment in Urban Safety-Net Primary Care Clinics: a Pragmatic Clinical Trial. J Gen Intern Med. 2019 Nov;34(11):2405-2413. PubMed PMID: 31485965
  • Iwamoto SJ, Defreyne J, Rothman MS, Van Schuylenbergh J, Van de Bruaene L, Motmans J, T'Sjoen G. Health considerations for transgender women and remaining unknowns: a narrative review. Ther Adv Endocrinol Metab. 2019;10:2042018819871166. PubMed PMID: 31516689
  • Saxon DR, Iwamoto SJ, Mettenbrink CJ, McCormick E, Arterburn D, Daley MF, Oshiro CE, Koebnick C, Horberg M, Young DR, Bessesen DH. Antiobesity Medication Use in 2.2 Million Adults Across Eight Large Health Care Organizations: 2009-2015. Obesity (Silver Spring). 2019 Dec;27(12):1975-1981. PubMed PMID: 31603630
  • Moreau KL, Iwamoto SJ, Runchey S. Aging and endocrinology. In: McDermott MT, editor. Endocrine Secrets 7. St. Louis, MO: Elsevier, Inc; 2020. p. 473-486.
  • Rothman MS, Iwamoto SJ. Gender-affirming treatment for adults with gender incongruence and gender dysphoria. In: McDermott MT, editor. Endocrine Secrets 7. St. Louis, MO: Elsevier, Inc; 2020. p. 438-445.
  • Iwamoto SJ, Cornier MA. Help, my metabolism is low! In: McDermott MT, editor. Management of patients with pseudo-endocrine disorders. Cham, Switzerland: Springer Nature Switzerland AG. 2019. p. 77-90.
  • Iwamoto S, Saxon D, Tsai A, Leister E, Speer R, Heyn H, Kealey E, Juarez-Colunga E, Gudzune K, Bleich S, Clark J, Bessesen D. Effects of Education and Experience on Primary Care Providers' Perspectives of Obesity Treatments during a Pragmatic Trial. Obesity (Silver Spring). 2018 Oct;26(10):1532-1538. PubMed PMID: 30257072
  • Nilsen J, Chen S, Irwin RW, Iwamoto S, Brinton RD. Estrogen protects neuronal cells from amyloid beta-induced apoptosis via regulation of mitochondrial proteins and function. BMC Neurosci. 2006 Nov 3;7:74. PubMed PMID: 17083736
View All (18 Total) View Less

Professional Memberships

  • Endocrine Society, Member
  • American Association of Clinical Endocrinologists, Member
  • World Professional Association for Transgender Health, Member
  • U.S. Professional Association for Transgender Health, Member
  • Colorado Society for Endocrinology and Metabolism, Member
  • GLMA Health Professionals Advancing LGBTQ Equality, Member

Practice Locations

UCHealth Diabetes and Endocrinology Clinic - Anschutz Medical Campus
1635 Aurora Ct
6th Floor
Aurora, CO 80045
720-848-2650

Rocky Mountain Regional Veterans Administration Medical Center
1700 Wheeling St
Aurora, CO 80045
303-399-8020

Hospital Affiliation
  • University of Colorado Hospital
  • Veterans Affairs Medical Center
Center Affiliations

Specialty Information

Specialties
  • Endocrinology, Diabetes and Metabolism, Board Certification (2017, 2017)
  • Internal Medicine, Board Certification (2014, 2014)
  • Equity Certificate Program - Office of Diversity, Equity, Inclusion & Community Engagement, Certificate (2021)
  • Pharmacogenomics Certificate Program, Certificate (2020)
Conditions & Treatments
  • Endocrine System (Hormones) - Adrenal Diseases
  • Endocrine System (Hormones)
  • Endocrine System (Hormones) - Adult Type 1 Diabetes
  • Endocrine System (Hormones) - Adult Type 2 Diabetes
  • Endocrine System (Hormones) - Endocrine Cancer (Parathyroid, Adrenal, Carcinoid)
  • Endocrine System (Hormones) - Lipidosis
  • Endocrine System (Hormones) - Osteoporosis
  • Endocrine System (Hormones) - Thyroid Cancer
  • Endocrine System (Hormones) - Thyroid Disease
  • Transgender Health
  • Food, Nutrition and Metabolism - Obesity
  • Food, Nutrition and Metabolism
Clinical Interests
General Endocrinology Transgender Health Obesity Aging

Volunteer Activities
Project Angel Heart; Co-Chair, Endocrine Society Special Interest Group for Transgender Research & Medicine; UCHealth Integrated Transgender Program Community Advisory Board

Public Speaking
Yes
General Endocrinology Transgender Health

General Information

Medical Schools:
  • MD, University of Rochester School of Medicine and Dentistry (2011)
Undergraduate Schools:
  • BA, Claremont McKenna College (2003)
Internships:
  • California Pacific Medical Center Program (2012)
Residency Programs:
  • California Pacific Medical Center Program, Chief Resident, Internal Medicine (2015)
Fellowships:
  • University of Colorado, Endocrinology, Diabetes and Metabolism (2017)
  • Denver Veterans Affairs Medical Center, Advanced Fellowship in Geriatrics (Geriatric Research, Education and Clinical Center) (2020)
Languages: English
Department: Medicine-Endocrinology/Metabolism/Diabetes
SOM Resources
CU Resources
Contact Us
CU Anschutz
Fitzsimons Building
13001 East 17th Place
Campus Box C290
Aurora, CO 80045

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