Matthew Wicklund, MD
Professor Adjoint, Neurology

Professional Titles

• Professor of Neurology

Recognition & Awards

• Best Doctors in America, Best Doctors (2020)
• Best Doctors in America, Best Doctors (2019)
• 5280 Top Doctors - Neuromuscular Medicine, 5280 Magazine (2019)
• Best Doctors in America, Best Doctors (2017)
• Best Doctors in America, Best Doctors (2016)
• Best Doctors in America, Best Doctors (2015)

Research Interests

Teaching

Publications

• Statland JM, Campbell C, Desai U, Karam C, Díaz-Manera J, Guptill JT, Korngut L, Genge A, Tawil RN, Elman L, Joyce NC, Wagner KR, Manousakis G, Amato AA, Butterfield RJ, Shieh PB, Wicklund M, Gamez J, Bodkin C, Pestronk A, Weihl CC, Vilchez-Padilla JJ, Johnson NE, Mathews KD, Miller B, Leneus A, Fowler M, van de Rijn M, Attie KM. Randomized phase 2 study of ACE-083, a muscle-promoting agent, in facioscapulohumeral muscular dystrophy. Muscle Nerve. 2022 Jul;66(1):50-62. PubMed PMID: 35428982
• Guglieri M, Bushby K, McDermott MP, Hart KA, Tawil R, Martens WB, Herr BE, McColl E, Speed C, Wilkinson J, Kirschner J, King WM, Eagle M, Brown MW, Willis T, Griggs RC, Straub V, van Ruiten H, Childs AM, Ciafaloni E, Shieh PB, Spinty S, Maggi L, Baranello G, Butterfield RJ, Horrocks IA, Roper H, Alhaswani Z, Flanigan KM, Kuntz NL, Manzur A, Darras BT, Kang PB, Morrison L, Krzesniak-Swinarska M, Mah JK, Mongini TE, Ricci F, von der Hagen M, Finkel RS, O'Reardon K, Wicklund M, Kumar A, McDonald CM, Han JJ, Joyce N, Henricson EK, Schara-Schmidt U, Gangfuss A, Wilichowski E, Barohn RJ, Statland JM, Campbell C, Vita G, Vita GL, Howard JF Jr, Hughes I, McMillan HJ, Pegoraro E, Bello L, Burnette WB, Thangarajh M, Chang T. Effect of Different Corticosteroid Dosing Regimens on Clinical Outcomes in Boys With Duchenne Muscular Dystrophy: A Randomized Clinical Trial. JAMA. 2022 Apr 19;327(15):1456-1468. PubMed PMID: 35381069
• Kovalchick LV, Bates K, Statland J, Weihl C, Kang PB, Lowes LP, Mozaffar T, Straub V, Wicklund M, Heatwole C, Johnson NE. Patient reported quality of life in limb girdle muscular dystrophy. Neuromuscul Disord. 2022 Jan;32(1):57-64. PubMed PMID: 34961728
• Korb M, Peck A, Alfano LN, Berger KI, James MK, Ghoshal N, Healzer E, Henchcliffe C, Khan S, Mammen PPA, Patel S, Pfeffer G, Ralston SH, Roy B, Seeley WW, Swenson A, Mozaffar T, Weihl C, Kimonis V. Development of a standard of care for patients with valosin-containing protein associated multisystem proteinopathy. Orphanet J Rare Dis. 2022 Jan 29;17(1):23. PubMed PMID: 35093159
• Smith K, Wicklund M. Genetic Diagnosis and Counseling in Muscular Dystrophies. Principles and Practice of Muscular Dystrophies - Current Clinical Neurology (2021). Accepted for publication.
• Campbell C, McColl E, McDermott MP, Martens WB, Guglieri M, Griggs RC. Health related quality of life in young, steroid-naïve boys with Duchenne muscular dystrophy. Neuromuscul Disord. 2021 Jun 10. [Epub ahead of print] PubMed PMID: 34489153
• Barohn RJ, Gajewski B, Pasnoor M, Brown A, Herbelin LL, Kimminau KS, Mudaranthakam DP, Jawdat O, Dimachkie MM, Iyadurai S, Stino A, Kissel J, Pascuzzi R, Brannagan T, Wicklund M, Ahmed A, Walk D, Smith G, Quan D, Heitzman D, Tobon A, Ladha S, Wolfe G, Pulley M, Hayat G, Li Y, Thaisetthawatkul P, Lewis R, Biliciler S, Sharma K, Salajegheh K, Trivedi J, Mallonee W, Burns T, Jacoby M, Bril V, Vu T, Ramchandren S, Bazant M, Austin S, Karam C, Hussain Y, Kutz C, Twydell P, Scelsa S, Kushlaf H, Wymer J, Hehir M, Kolb N, Ralph J, Barboi A, Verma N, Ahmed M, Memon A, Saperstein D, Lou JS, Swenson A, Cash T. Patient Assisted Intervention for Neuropathy: Comparison of Treatment in Real Life Situations (PAIN-CONTRoLS): Bayesian Adaptive Comparative Effectiveness Randomized Trial. JAMA Neurol. 2020 Aug 17. [Epub ahead of print] PubMed PMID: 32809014
• Bockhorst J, Wicklund M. Limb Girdle Muscular Dystrophies. Neurol Clin. 2020 Aug;38(3):493-504. PubMed PMID: 32703463
• Clemens PR, Niizawa G, Feng J, Florence J, D'Alessandro AS, Morgenroth LP, Gorni K, Guglieri M, Connolly A, Wicklund M, Bertorini T, Mah JK, Thangarajh M, Smith E, Kuntz N, McDonald CM, Henricson EK, Upadhyayula S, Byrne B, Manousakis G, Harper A, Bravver E, Iannaccone S, Spurney C, Cnaan A, Gordish-Dressman H. The CINRG Becker Natural History Study: Baseline characteristics. Muscle Nerve. 2020 Sep;62(3):369-376. PubMed PMID: 32564389
• Kern V, Wicklund M, Haulman A, McDermott MP, Martens WB, Griggs RC, Kumar A. Ankle bracing practices in ambulatory, corticosteroid-naive boys with Duchenne muscular dystrophy. Muscle Nerve. 2020 Jan;61(1):52-57. PubMed PMID: 31588574
• Aburahma SK, Wicklund MP, Quan D. Take two: Utility of the repeat skeletal muscle biopsy. Muscle Nerve. 2019 Jul;60(1):41-46. PubMed PMID: 30972775
• Hunter M, Heatwole C, Wicklund M, Weihl CC, Mozaffar T, Statland JM, Johnson NE. Limb-girdle muscular dystrophy: A perspective from adult patients on what matters most. Muscle Nerve. 2019 Oct;60(4):419-424. PubMed PMID: 31298728
• Kern V, Wicklund M, Haulman A, McDermott MP, Martens WB, Griggs RC, Kumar A. Ankle bracing practices in ambulatory, corticosteroid-naive boys with Duchenne muscular dystrophy. Muscle Nerve. 2019 Oct 6. [Epub ahead of print] PubMed PMID: 31588574
• Wicklund MP. The Limb-Girdle Muscular Dystrophies. Continuum (Minneap Minn). 2019 Dec;25(6):1599-1618. PubMed PMID: 31794462
• Piquet AL, Khan M, Warner JEA, Wicklund MP, Bennett JL, Leehey MA, Seeberger L, Schreiner TL, Paz Soldan MM, Clardy SL. Novel clinical features of glycine receptor antibody syndrome: A series of 17 cases. Neurol Neuroimmunol Neuroinflamm. 2019 Sep;6(5):e592. PubMed PMID: 31355325
• He C, Lee JS, Cool CD, Wicklund MP, Fischer A. Development of Autoimmune Interstitial Lung Disease in a Patient with Inclusion Body Myositis. Am J Med. 2019 Dec;132(12):e854-e855. PubMed PMID: 31310746
• Hunter M, Heatwole C, Wicklund M, Weihl CC, Mozaffar T, Statland JM, Johnson NE. Limb-girdle muscular dystrophy: A perspective from adult patients on what matters most. Muscle Nerve. 2019 Oct;60(4):419-424. PubMed PMID: 31298728
• Xu F, Takahashi H, Tanaka Y, Ichinose S, Niwa S, Wicklund MP, Hirokawa N. KIF1Bß mutations detected in hereditary neuropathy impair IGF1R transport and axon growth. J Cell Biol. 2018 Oct 1;217(10):3480-3496. PubMed PMID: 30126838
• Kumar A, Asghar S, Kavanagh R, Wicklund MP. Unique presentation of rapidly fluctuating symptoms in a child with congenital myasthenic syndrome due to RAPSN mutation. Muscle Nerve. 2018 Oct;58(4):E23-E24. PubMed PMID: 30028532
• Crow RA, Hart KA, McDermott MP, Tawil R, Martens WB, Herr BE, McColl E, Wilkinson J, Kirschner J, King WM, Eagle M, Brown MW, Hirtz D, Lochmuller H, Straub V, Ciafaloni E, Shieh PB, Spinty S, Childs AM, Manzur AY, Morandi L, Butterfield RJ, Horrocks I, Roper H, Flanigan KM, Kuntz NL, Mah JK, Morrison L, Darras BT, von der Hagen M, Schara U, Wilichowski E, Mongini T, McDonald CM, Vita G, Barohn RJ, Finkel RS, Wicklund M, McMillan HJ Jr, Hughes I, Pegoraro E, Bryan Burnette W, Howard JF, Thangarajh M, Campbell C, Griggs RC, Bushby K, Guglieri M. A checklist for clinical trials in rare disease: obstacles and anticipatory actions-lessons learned from the FOR-DMD trial. Trials. 2018 May 10;19(1):291. PubMed PMID: 29793540
• Al-Tahan S, Al-Obeidi E, Yoshioka H, Lakatos A, Weiss L, Grafe M, Palmio J, Wicklund M, Harati Y, Omizo M, Udd B, Kimonis V. Novel valosin-containing protein mutations associated with multisystem proteinopathy. Neuromuscul Disord. 2018 Jun;28(6):491-501. PubMed PMID: 29754758
• Giampetro D, Ruiz-Velasco V, Pruett A, Wicklund M, Knipe R. The Effect of Propofol on Chronic Headaches in Patients Undergoing Endoscopy. Pain Res Manag. 2018;2018:6018404. PubMed PMID: 29610631
• Nallamilli BRR, Chakravorty S, Kesari A, Tanner A, Ankala A, Schneider T, da Silva C, Beadling R, Alexander JJ, Askree SH, Whitt Z, Bean L, Collins C, Khadilkar S, Gaitonde P, Dastur R, Wicklund M, Mozaffar T, Harms M, Rufibach L, Mittal P, Hegde M. Genetic landscape and novel disease mechanisms from a large LGMD cohort of 4656 patients. Ann Clin Transl Neurol. 2018 Dec;5(12):1574-1587. PubMed PMID: 30564623
• Guglieri M, Bushby K, McDermott MP, Hart KA, Tawil R, Martens WB, Herr BE, McColl E, Wilkinson J, Kirschner J, King WM, Eagle M, Brown MW, Willis T, Hirtz D, Shieh PB, Straub V, Childs AM, Ciafaloni E, Butterfield RJ, Horrocks I, Spinty S, Flanigan KM, Kuntz NL, Baranello G, Roper H, Morrison L, Mah JK, Manzur AY, McDonald CM, Schara U, von der Hagen M, Barohn RJ, Campbell C, Darras BT, Finkel RS, Vita G, Hughes I, Mongini T, Pegoraro E, Wicklund M, Wilichowski E, Bryan Burnette W, Howard JF, McMillan HJ, Thangarajh M, Griggs RC. Developing standardized corticosteroid treatment for Duchenne muscular dystrophy. Contemp Clin Trials. 2017 Jul;58:34-39. PubMed PMID: 28450193
• Ibrahimi M, Nozaki H, Lee A, Onodera O, Reichwein R, Wicklund M, El-Ghanem M. A CARASIL Patient from Americas with Novel Mutation and Atypical Features: Case Presentation and Literature Review. Cerebrovasc Dis. 2017;44(3-4):135-140. PubMed PMID: 28628911
• Smith K, Wicklund M. Genetic Diagnosis and Counseling in Muscular Dystrophies. Principles and Practice of Muscular Dystrophies - Current Clinical Neurology (2021). In press.

Professional Memberships

• American Academy of Neurology, Fellow
• FSHD Society, Member
• American Neurological Association, Member
• Muscle Study Group, Member