Faculty Profile | School of Medicine | University of Colorado Denver

Pratap A, Qualman A, Garrett H, Westbrook L, The E, Mitra S, Cordero M, Monge KM, Idrovo JP, Chauhan A, Cheng L, Cohen MJ, Mungo B, Wani S, Meguid RA, McCarter MD, Meng X. Silencing Glypican-1 enhances the antitumor effects of Pictilisib via downregulating PI3K/Akt/ERK signaling in chemo-resistant esophageal adenocarcinoma. Mol Cell Oncol. 2023;10(1):2238873. PubMed PMID: 37649964

Cralley AL, Erickson C, Schaid TR Jr, Hallas W, Thielen O, Mitra S, Stafford P, Hom P, Silliman C, Cohen MJ, Moore EE, D'Alessandro A, Hansen KC. The proteomic and metabolomic signatures of isolated and polytrauma traumatic brain injury. Am J Surg. 2023 Dec;226(6):790-797. PubMed PMID: 37541795

Coleman JR, D'Alessandro A, LaCroix I, Dzieciatkowska M, Lutz P, Mitra S, Gamboni F, Ruf W, Silliman CC, Cohen MJ. A metabolomic and proteomic analysis of pathologic hypercoagulability in traumatic brain injury patients after dura violation. J Trauma Acute Care Surg. 2023 Dec 1;95(6):925-934. PubMed PMID: 37405823

Coleman JJ, Robinson CK, von Hippel W, Holmes KE, Kim J, Pearson S, Lawless RA, Hubbard AE, Cohen MJ. What Happens on Call Doesn't Stay on Call. The Effects of In-house Call on Acute Care Surgeons' Sleep and Burnout: Results of the Surgeon Performance (SuPer) Trial. Ann Surg. 2023 Oct 1;278(4):497-505. PubMed PMID: 37389574

Cralley AL, Moore EE, Sauaia A, Carani PH, Schaid TR Jr, DeBot M, Fragoso M, Ghasabyan A, Hansen K, Cohen MJ, Silliman CC, Fox CJ. REBOA for the Treatment of Blast Polytrauma: Zone 3 Provides Cerebral Perfusion, Attenuates Organ Dysfunction and Reperfusion Coagulopathy Compared to Zone 1 in a Swine Model. J Trauma Acute Care Surg. 2023 May 1;94(5):718-724. PubMed PMID: 36749658

DeBot M, Erickson C, Kelher M, Schaid TR Jr, Moore EE, Sauaia A, Cralley A, LaCroix I, D'Alessandro A, Hansen K, Cohen MJ, Silliman CC, Coleman J. Platelet and cryoprecipitate transfusions from female donors improve coagulopathy in vitro. J Trauma Acute Care Surg. 2023 Apr 1;94(4):497-503. PubMed PMID: 36728345

Schaid TR Jr, LaCroix I, Hansen KC, D'Alessandro A, Moore EE, Sauaia A, Dzieciatkowska M, DeBot M, Cralley AL, Thielen O, Hallas W, Erickson C, Mitra S, Banerjee A, Jones K, Silliman CC, Cohen MJ. A proteomic analysis of NETosis in trauma: Emergence of serpinB1 as a key player. J Trauma Acute Care Surg. 2023 Mar 1;94(3):361-370. PubMed PMID: 36730076

Eitel AP, Moore EE, Sauaia A, Kelher MR, Vigneshwar NG, Bartley MG, Hadley JB, Burlew CC, Campion EM, Fox CJ, Lawless RA, Pieracci FM, Platnick KB, Moore HB, Cohen MJ, Silliman CC. A proposed clinical coagulation score for research in trauma-induced coagulopathy. J Trauma Acute Care Surg. 2023 Jun 1;94(6):798-802. PubMed PMID: 36805626

Coleman JR, Moore EE, Schmitt L, Hansen K, Dow N, Freeman K, Cohen MJ, Silliman CC. Estradiol provokes hypercoagulability and affects fibrin biology: A mechanistic exploration of sex dimorphisms in coagulation. J Trauma Acute Care Surg. 2023 Feb 1;94(2):179-186. PubMed PMID: 36694329

Cralley AL, Moore EE, Coleman JR, Vigneshwar N, Bartley M, Kissau D, Eitel A, Hom P, Mitra S, Ghasabyan A, Fragoso M, Guo Z, Deguchi H, Griffin JH, Cohen MJ, Silliman CC, Banerjee A, Hansen K, Sauaia A. Hemorrhagic shock and tissue injury provoke distinct components of trauma-induced coagulopathy in a swine model. Eur J Trauma Emerg Surg. 2023 Apr;49(2):1079-1089. PubMed PMID: 36319860

Coleman JR, Moore EE, Kelher MR, Jones K, Cohen MJ, Banerjee A, Silliman CC. Elucidating the molecular mechanisms of fibrinolytic shutdown after severe injury: The role of thrombin-activatable fibrinolysis inhibitor. J Trauma Acute Care Surg. 2023 Jun 1;94(6):857-862. PubMed PMID: 36787438

Coleman JR, Fabbri S, Anderson M, Moore EE, Cohen MJ, Hadley J, Ghasabyan A, Chandler J, Kelher M, Freeman K, Miller ZD, Silliman CC. Beyond uterine atony: characterizing postpartum hemorrhage coagulopathy. Am J Obstet Gynecol MFM. 2023 Mar;5(3):100822. PubMed PMID: 36464240

Moazed F, Hendrickson C, Jauregui A, Gotts J, Conroy A, Delucchi K, Zhuo H, Arambulo M, Vessel K, Ke S, Deiss T, Ni A, Leligdowicz A, Abbott J, Cohen MJ, Sinha P, Gomez A, Kangelaris K, Kornblith L, Matthay M, Benowitz N, Liu K, Calfee CS. Cigarette Smoke Exposure and ARDS in Sepsis: Epidemiology, Clinical Features, and Biologic Markers. Am J Respir Crit Care Med. 2022 Jan 20. [Epub ahead of print] PubMed PMID: 35050845

Joseph BC, Miyazawa BY, Esmon CT, Cohen MJ, von Drygalski A, Mosnier LO. An engineered activated factor V for the prevention and treatment of acute traumatic coagulopathy and bleeding in mice. Blood Adv. 2022 Feb 8;6(3):959-969. PubMed PMID: 34861695

DeBot M, Mitra S, Lutz P, Schaid TR Jr, Stafford P, Hadley JB, Hom P, Sauaia A, Silliman CC, Moore EE, Cohen MJ. SHOCK INDUCES ENDOTHELIAL PERMEABILITY AFTER TRAUMA THROUGH INCREASED ACTIVATION OF RHOA GTPASE. Shock. 2022 Dec 1;58(6):542-548. PubMed PMID: 36548645

Prins JTH, Leasia K, Sauaia A, Burlew CC, Cohen MJ, Coleman JJ, Lawless RA, Platnick KB, Werner NL, Wijffels MME, Moore EE, Pieracci FM. A decade of surgical stabilization of rib fractures: the effect of study year on patient selection, operative characteristics, and in-hospital outcome. Injury. 2021 Dec 16. [Epub ahead of print] PubMed PMID: 34953578

Ghetmiri DE, Cohen MJ, Menezes AA. Personalized modulation of coagulation factors using a thrombin dynamics model to treat trauma-induced coagulopathy. NPJ Syst Biol Appl. 2021 Dec 7;7(1):44. PubMed PMID: 34876597

Bouchard BA, Colovos C, Lawson MA, Osborn ZT, Sackheim AM, Mould KJ, Janssen WJ, Cohen MJ, Majumdar D, Freeman K. Increased histone-DNA complexes and endothelial-dependent thrombin generation in severe COVID-19. Vascul Pharmacol. 2021 Dec 3;142:106950. [Epub ahead of print] PubMed PMID: 34871770

Leasia KN, Ciarallo C, Prins JTH, Preslaski C, Perkins-Pride E, Hardin K, Cralley A, Burlew CC, Coleman JJ, Cohen MJ, Lawless R, Platnick KB, Moore EE, Pieracci FM. A randomized clinical trial of single dose liposomal bupivacaine versus indwelling analgesic catheter in patients undergoing surgical stabilization of rib fractures. J Trauma Acute Care Surg. 2021 Nov 1;91(5):872-878. PubMed PMID: 33951024

McCully BH, Wade CE, Fox EE, Inaba K, Cohen MJ, Holcomb JB, Schreiber MA. Temporal profile of the pro- and anti-inflammatory responses to severe hemorrhage in patients with venous thromboembolism: Findings from the PROPPR trial. J Trauma Acute Care Surg. 2021 May 1;90(5):845-852. PubMed PMID: 33797501

Hadley JB, Coleman JR, Moore EE, Lawless R, Burlew CC, Platnick B, Pieracci FM, Hoehn MR, Coleman JJ, Campion EM, Cohen MJ, Cralley A, Eitel AP, Bartley M, Vigneshwar N, Sauaia A, Fox CJ. Strategies for successful implementation of resuscitative endovascular balloon occlusion of the aorta in an urban Level I trauma center. J Trauma Acute Care Surg. 2021 Aug 1;91(2):295-301. PubMed PMID: 33783417

Samuels JM, Sun K, Moore EE, Coleman JR, Fox CJ, Cohen MJ, Sauaia A, MacTaggart JN. Trauma surgeons as the vanguard for safe REBOA implementation-response to letter to the editor. J Trauma Acute Care Surg. 2021 May 1;90(5):e127. PubMed PMID: 33417409

Vulliamy P, Kornblith LZ, Kutcher ME, Cohen MJ, Brohi K, Neal MD. Alterations in platelet behavior after major trauma: adaptive or maladaptive?. Platelets. 2021 Apr 3;32(3):295-304. PubMed PMID: 31986948

Pusateri AE, Le TD, Keyloun JW, Moffatt LT, Orfeo T, Brummel-Ziedins KE, McLawhorn MM, Callcut RA, Shupp JW. Early abnormal fibrinolysis and mortality in patients with thermal injury: a prospective cohort study. BJS Open. 2021 Mar 5;5(2). PubMed PMID: 33893737

Jiang RM, Pourzanjani AA, Cohen MJ, Petzold L. Associations of longitudinal D-Dimer and Factor II on early trauma survival risk. BMC Bioinformatics. 2021 Mar 13;22(1):122. PubMed PMID: 33714270

Farrell MS, Moore EE, Thomas AV, Coleman JR, Thomas S, Vande Lune S, Marconi T Jr, Cohen MJ, Chapman MP, Moore HB, Walsh MM, Sixta S. "Death Diamond" Tracing on Thromboelastography as a Marker of Poor Survival After Trauma. Am Surg. 2021 Feb 25;:3134821998684. [Epub ahead of print] PubMed PMID: 33629880

Coleman JR, Moore EE, Samuels JM, Cohen MJ, Silliman CC, Ghasabyan A, Chandler J, Butenas S. Whole Blood Thrombin Generation in Severely Injured Patients Requiring Massive Transfusion. J Am Coll Surg. 2021 May;232(5):709-716. PubMed PMID: 33548446

Samuels JM, Sun K, Moore EE, Coleman JR, Fox CJ, Cohen MJ, Sauaia A, MacTaggart JN. Trauma surgeons as the vanguard for safe REBOA implementation-response to letter to the editor. J Trauma Acute Care Surg. 2021 May 1;90(5):e127. PubMed PMID: 33417409

Schwed AC, Wagenaar A, Reppert AE, Gore AV, Pieracci FM, Platnick KB, Lawless RA, Campion EM, Coleman JJ, Cohen MJ, Moore EE, Burlew CC. Trust the FAST: Confirmation that the FAST examination is highly specific for intra-abdominal hemorrhage in over 1,200 patients with pelvic fractures. J Trauma Acute Care Surg. 2021 Jan 1;90(1):137-142. PubMed PMID: 32976327

Samuels JM, Sun K, Moore EE, Coleman JR, Fox CJ, Cohen MJ, Sauaia A, MacTaggart JN. Trauma surgeons as the vanguard for safe REBOA implementation-response to letter to the editor. J Trauma Acute Care Surg. 2021 May 1;90(5):e127. PubMed PMID: 33417409

Heelan AA, Freedberg M, Moore EE, Platnick BK, Pieracci FM, Cohen MJ, Lawless R, Campion EM, Coleman JJ, Hoehn M, Burlew CC. Worth looking! venous thromboembolism in patients who undergo preperitoneal pelvic packing warrants screening duplex. Am J Surg. 2020 Dec;220(6):1395-1399. PubMed PMID: 32958159

de Roulet A, Kerby JD, Weinberg JA, Lewis RH Jr, Hudgins JP, Shulman IA, Fox EE, Holcomb JB, Brasel KJ, Bulger EM, Cohen MJ, Cotton BA, Fabian TC, O'Keeffe T, Rizoli S, Scalea TM, Schreiber MA, Inaba K. Group A emergency-release plasma in trauma patients requiring massive transfusion. J Trauma Acute Care Surg. 2020 Dec;89(6):1061-1067. PubMed PMID: 32890339

Coleman JR, Moore EE, Vintimilla DR, Parry J, Nelson JT, Samuels JM, Sauaia A, Cohen MJ, Burlew CC, Mauffrey C. Association between Young-Burgess pelvic ring injury classification and concomitant injuries requiring urgent intervention. J Clin Orthop Trauma. 2020 Nov-Dec;11(6):1099-1103. PubMed PMID: 33192014

Nunns GR, Vigneshwar N, Kelher MR, Stettler GR, Gera L, Reisz JA, D'Alessandro A, Ryon J, Hansen KC, Gamboni F, Moore EE, Peltz ED, Cohen MJ, Jones KL, Sauaia A, Liang X, Banerjee A, Ghasabyan A, Chandler JG, Rodawig S, Jones C, Eitel A, Hom P, Silliman CC. Succinate Activation of SUCNR1 Predisposes Severely Injured Patients to Neutrophil-Mediated ARDS. Ann Surg. 2020 Nov 18. [Epub ahead of print] PubMed PMID: 33214479

Kovar A, Moskowitz E, Sauaia A, Moore EE, Platnick KB, Coleman JJ, Campion EM, Lawless RA, Cohen MJ, Pieracci FM, Burlew CC. Trends in hematologic markers after blunt splenic trauma: Risk factor or Epiphenomenon?. Am J Surg. 2019 Dec 20. [Epub ahead of print] PubMed PMID: 31879019

Coleman JR, Moore EE, Sauaia A, Samuels JM, Moore HB, Ghasabyan A, Chandler JG, Swope ML, Fleming CD, Banerjee A, Cohen MJ, Silliman CC, Peltz ED, Chapman MP. Untangling Sex Dimorphisms in Coagulation: Initial Steps Towards Precision Medicine for Trauma Resuscitation. Ann Surg. 2019 Dec 10. [Epub ahead of print] PubMed PMID: 31850983

Moore HB, Cohen MJ, Moore EE. Comment on The S100A10 Pathway Mediates an Occult Hyperfibrinolytic Subtype in Trauma Patients. Ann Surg. 2019 Nov 20. [Epub ahead of print] PubMed PMID: 31800497

Coleman JR, Moore EE, Zilberman-Rudenko J, Samuels JM, Cohen MJ, Silliman CC, Banerjee A, Sauaia A, Griffin JH, Deguchi H. Cardiac and Skeletal Muscle Myosin Exert Procoagulant Effects. Shock. 2019 Nov;52(5):554-555. PubMed PMID: 31613865

Coleman JR, Kay AB, Moore EE, Moore HB, Gonzalez E, Majercik S, Cohen MJ, White T, Pieracci FM. It's sooner than you think: Blunt solid organ injury patients are already hypercoagulable upon hospital admission - Results of a bi-institutional, prospective study. Am J Surg. 2019 Dec;218(6):1065-1073. PubMed PMID: 31540685

Lalezari A, Cohen MJ, Svinik O, Tel-Zur O, Sinvani S, Al-Dayem YA, Block C, Moses AE, Oster Y, Salameh S, Strahilevitz J. A simplified blood culture sampling protocol for reducing contamination and costs: a randomized controlled trial. Clin Microbiol Infect. 2019 Sep 17. [Epub ahead of print] PubMed PMID: 31539635

Fernandes AG, Salomão SR, Ferraz NN, Mitsuhiro MH, Furtado JM, Muñoz S, Cypel MC, Cunha CC, Vasconcelos GC, Sacai PY, Morales PH, Cohen MJ, Cohen JM, Watanabe SS, Campos M, Belfort Junior R, Berezovsky A. Pterygium in adults from the Brazilian Amazon Region: prevalence, visual status and refractive errors. Br J Ophthalmol. 2019 Sep 18. [Epub ahead of print] PubMed PMID: 31533928

Coleman JR, Moore EE, Samuels JM, Ryon JJ, Nelson JT, Olson A, Caus S, Bartley MG, Vigneshwar NG, Cohen MJ, Banerjee A, Silliman CC, Butenas S. Whole blood thrombin generation is distinct from plasma thrombin generation in healthy volunteers and after severe injury. Surgery. 2019 Dec;166(6):1122-1127. PubMed PMID: 31522748

Ben-Chetrit E, Oster Y, Jarjou'i A, Megged O, Lachish T, Cohen MJ, Stein-Zamir C, Ivgi H, Rivkin M, Milgrom Y, Averbuch D, Korem M, Wolf DG, Wiener-Well Y. Measles-related hospitalizations and associated complications in Jerusalem, 2018-2019. Clin Microbiol Infect. 2019 Sep 6. [Epub ahead of print] PubMed PMID: 31499179

Kornblith LZ, Moore HB, Cohen MJ. Response to Letter to the Editor submitted by Dr. Gando and Dr. Otomo re: Trauma-induced coagulopathy: The past, present, and future. J Thromb Haemost. 2019 Sep;17(9):1569-1571. PubMed PMID: 31479186

Kornblith LZ, Moore HB, Cohen MJ. Response to Letter to the Editor submitted by Dr. Wada and Dr. Yamakawa re: Trauma-induced coagulopathy: The past, present, and future. J Thromb Haemost. 2019 Sep;17(9):1574-1576. PubMed PMID: 31479184

Levin PD, Cohen MJ, Ohev-Zion E, Tannus S, Stohl S, Avidan A, Cohen-Poraduso R, Moses AE, Sprung CL, Benenson S. The Effect of Repeated Versus Initial Procalcitonin Measurements on Diagnosis of Infection in the Intensive Care Setting: A Prospective Observational Study. Anesth Analg. 2019 Oct;129(4):e114-e117. PubMed PMID: 29505445

Gordon O, Cohen MJ, Gross I, Amit S, Averbuch D, Engelhard D, Milstone AM, Moses AE. Staphylococcus aureus Bacteremia in Children: Antibiotic Resistance and Mortality. Pediatr Infect Dis J. 2019 May;38(5):459-463. PubMed PMID: 30239476

Shupp JW, Brummel-Ziedins KE, Cohen MJ, Freeman K, Hammamieh R, Mudunuri US, Orfeo T, Moffatt LT, Brownstein BH, Mann KG, Jett M, Pusateri AE. Assessment of Coagulation Homeostasis in Blunt, Penetrating, and Thermal Trauma: Guidance for a Multicenter Systems Biology Approach. Shock. 2019 Oct;52(1S Suppl 1):84-91. PubMed PMID: 30339633

Pirracchio R, Cohen MJ, Malenica I, Cohen J, Chambaz A, Cannesson M, Lee C, Resche-Rigon M, Hubbard A. Big data and targeted machine learning in action to assist medical decision in the ICU. Anaesth Crit Care Pain Med. 2019 Aug;38(4):377-384. PubMed PMID: 30339893

Roberts DJ, Kalkwarf KJ, Moore HB, Cohen MJ, Fox EE, Wade CE, Cotton BA. Time course and outcomes associated with transient versus persistent fibrinolytic phenotypes after injury: A nested, prospective, multicenter cohort study. J Trauma Acute Care Surg. 2019 Feb;86(2):206-213. PubMed PMID: 30376538

Lester ELW, Fox EE, Holcomb JB, Brasel KJ, Bulger EM, Cohen MJ, Cotton BA, Fabian TC, Kerby JD, O'Keefe T, Rizoli SB, Scalea TM, Schreiber MA, Inaba K. The impact of hypothermia on outcomes in massively transfused patients. J Trauma Acute Care Surg. 2019 Mar;86(3):458-463. PubMed PMID: 30444856

Robles AJ, Conroy AS, Cohen MJ, Callcut RA. Is it time to measure complications from the National Trauma Data Bank? A longitudinal analysis of recent reporting trends. J Trauma Acute Care Surg. 2019 Feb;86(2):282-288. PubMed PMID: 30489507

Hodgman EI, Cripps MW, Mina MJ, Bulger EM, Schreiber MA, Brasel KJ, Cohen MJ, Muskat P, Myers JG, Alarcon LH, Rahbar MH, Holcomb JB, Cotton BA, Fox EE, Del Junco DJ, Wade CE, Phelan HA. External validation of a smartphone app model to predict the need for massive transfusion using five different definitions. J Trauma Acute Care Surg. 2018 Feb;84(2):397-402. PubMed PMID: 29200079

Robinson BRH, Cohen MJ, Holcomb JB, Pritts TA, Gomaa D, Fox EE, Branson RD, Callcut RA, Cotton BA, Schreiber MA, Brasel KJ, Pittet JF, Inaba K, Kerby JD, Scalea TM, Wade CE, Bulger EM. Risk Factors for the Development of Acute Respiratory Distress Syndrome Following Hemorrhage. Shock. 2018 Sep;50(3):258-264. PubMed PMID: 29194339

Moskowitz EE, Burlew CC, Moore EE, Pieracci FM, Fox CJ, Campion EM, Lawless RA, Cohen MJ. Preperitoneal pelvic packing is effective for hemorrhage control in open pelvic fractures. Am J Surg. 2018 Apr;215(4):675-677. PubMed PMID: 29179908

Kunitake RC, Kornblith LZ, Cohen MJ, Callcut RA. Trauma Early Mortality Prediction Tool (TEMPT) for assessing 28-day mortality. Trauma Surg Acute Care Open. 2018;3(1):e000131. PubMed PMID: 29766125

Moazed F, Hendrickson C, Nelson M, Conroy A, Cohen MJ, Calfee CS. Platelet aggregation after blunt trauma is associated with the acute respiratory distress syndrome and altered by cigarette smoke exposure. J Trauma Acute Care Surg. 2018 Feb;84(2):365-371. PubMed PMID: 29140951

Robles AJ, Kornblith LZ, Hendrickson CM, Howard BM, Conroy AS, Moazed F, Calfee CS, Cohen MJ, Callcut RA. Health care utilization and the cost of posttraumatic acute respiratory distress syndrome care. J Trauma Acute Care Surg. 2018 Jul;85(1):148-154. PubMed PMID: 29958249

Woolley T, Thompson P, Kirkman E, Reed R, Ausset S, Beckett A, Bjerkvig C, Cap AP, Coats T, Cohen M, Despasquale M, Dorlac W, Doughty H, Dutton R, Eastridge B, Glassberg E, Hudson A, Jenkins D, Keenan S, Martinaud C, Miles E, Moore E, Nordmann G, Prat N, Rappold J, Reade MC, Rees P, Rickard R, Schreiber M, Shackelford S, Skogran Eliassen H, Smith J, Smith M, Spinella P, Strandenes G, Ward K, Watts S, White N, Williams S. Trauma Hemostasis and Oxygenation Research Network position paper on the role of hypotensive resuscitation as part of remote damage control resuscitation. J Trauma Acute Care Surg. 2018 Jun;84(6S Suppl 1):S3-S13. PubMed PMID: 29799823

Wu TB, Wu S, Buoni M, Orfeo T, Brummel-Ziedins K, Cohen M, Petzold L. Computational Model for Hyperfibrinolytic Onset of Acute Traumatic Coagulopathy. Ann Biomed Eng. 2018 Aug;46(8):1173-1182. PubMed PMID: 29675813

Burlew CC, Sumislawski JJ, Behnfield CD, McNutt MK, McCarthy J, Sharpe JP, Croce MA, Bala M, Kashuk J, Spalding MC, Beery PR, John S, Hunt DJ, Harmon L, Stein DM, Callcut R, Wybourn C, Sperry J, Anto V, Dunn J, Veith JP, Brown CVR, Celii A, Zander TL, Coimbra R, Berndtson AE, Moss TZ, Malhotra AK, Hazelton JP, Linden K, West M, Alam HB, Williams AM, Kim J, Inaba K, Moulton S, Choi YM, Warren HL, Collier B, Ball CG, Savage S, Hartwell JL, Cullinane DC, Zielinski MD, Ray-Zack MD, Morse BC, Rhee P, Rutherford EJ, Udekwu P, Reynolds C, Toschlog E, Gondek S, Ju T, Haan JM, Lightwine KL, Kulvatunyou N, Coates B, Khouqeer AF, Todd SR, Zarzaur B, Waller CJ, Kallies KJ, Neideen T, Eddine SBZ, Peck KA, Dunne CE, Kramer K, Bokhari F, Dhillon TS, Galante JM, Cohen MJ. TIME TO STROKE: A WESTERN TRAUMA ASSOCIATION MULTI-CENTER STUDY OF BLUNT CEREBROVASCULAR INJURIES. J Trauma Acute Care Surg. 2018 May 25. [Epub ahead of print] PubMed PMID: 29847537

Hendrickson CM, Gibb SL, Miyazawa BY, Keating SM, Ross E, Conroy AS, Calfee CS, Pati S, Cohen MJ. Elevated plasma levels of TIMP-3 are associated with a higher risk of acute respiratory distress syndrome and death following severe isolated traumatic brain injury. Trauma Surg Acute Care Open. 2018;3(1):e000171. PubMed PMID: 30023434

Kornblith LZ, Robles AJ, Conroy AS, Hendrickson CM, Calfee CS, Fields AT, Callcut RA, Cohen MJ. Perhaps It's Not the Platelet: Ristocetin Uncovers the Potential Role of von Willebrand Factor in Impaired Platelet Aggregation Following Traumatic Brain Injury. J Trauma Acute Care Surg. 2018 Jul 5. [Epub ahead of print] PubMed PMID: 29985231

Stettler GR, Sumislawski JJ, Moore EE, Nunns GR, Kornblith LZ, Conroy AS, Callcut RA, Silliman CC, Banerjee A, Cohen MJ, Sauaia A. Citrated Kaolin Thrombelastography (TEG) Thresholds for Goal-Directed Therapy in Injured Patients Receiving Massive Transfusion. J Trauma Acute Care Surg. 2018 Jul 27. [Epub ahead of print] PubMed PMID: 30059456

Ariane Christie S, Hubbard AE, Callcut RA, Hameed M, Dissak-Delon FN, Mekolo D, Saidou A, Mefire AC, Nsongoo P, Dicker RA, Cohen MJ, Juillard C. Machine Learning Without Borders? An Adaptable Tool to Optimize Mortality Prediction in Diverse Clinical Settings. J Trauma Acute Care Surg. 2018 Jul 27. [Epub ahead of print] PubMed PMID: 30059457

Panzer AR, Lynch SV, Langelier C, Christie JD, McCauley K, Nelson M, Cheung CK, Benowitz NL, Cohen MJ, Calfee CS. Lung Microbiota Is Related to Smoking Status and to Development of Acute Respiratory Distress Syndrome in Critically Ill Trauma Patients. Am J Respir Crit Care Med. 2018 Mar 1;197(5):621-631. PubMed PMID: 29035085

Nunns GR, Moore EE, Stettler GR, Moore HB, Ghasabyan A, Cohen M, Huebner BR, Silliman CC, Banerjee A, Sauaia A. Empiric transfusion strategies during life-threatening hemorrhage. Surgery. 2018 Aug;164(2):306-311. PubMed PMID: 29709368

Menezes AA, Vilardi RF, Arkin AP, Cohen MJ. Targeted clinical control of trauma patient coagulation through a thrombin dynamics model. Sci Transl Med. 2017 Jan 4;9(371). PubMed PMID: 28053156

Davenport RA, Guerreiro M, Frith D, Rourke C, Platton S, Cohen M, Pearse R, Thiemermann C, Brohi K. Activated Protein C Drives the Hyperfibrinolysis of Acute Traumatic Coagulopathy. Anesthesiology. 2017 Jan;126(1):115-127. PubMed PMID: 27841821

Kunitake RC, Howard BM, Kornblith LZ, Christie SA, Conroy AS, Cohen MJ, Callcut RA. Individual clotting factor contributions to mortality following trauma. J Trauma Acute Care Surg. 2017 Feb;82(2):302-308. PubMed PMID: 27906868

Cannon JW, Khan MA, Raja AS, Cohen MJ, Como JJ, Cotton BA, Dubose JJ, Fox EE, Inaba K, Rodriguez CJ, Holcomb JB, Duchesne JC. Damage control resuscitation in patients with severe traumatic hemorrhage: A practice management guideline from the Eastern Association for the Surgery of Trauma. J Trauma Acute Care Surg. 2017 Mar;82(3):605-617. PubMed PMID: 28225743

Rowell SE, Biffl WL, Brasel K, Moore EE, Albrecht RA, DeMoya M, Namias N, Schreiber MA, Cohen MJ, Shatz DV, Karmy-Jones R, Moore FA. Western Trauma Association Critical Decisions in Trauma: Management of adult blunt splenic trauma-2016 updates. J Trauma Acute Care Surg. 2017 Apr;82(4):787-793. PubMed PMID: 27893644

Christie SA, Kornblith LZ, Howard BM, Conroy AS, Kunitake RC, Nelson MF, Hendrickson CM, Calfee CS, Callcut RA, Cohen MJ. Characterization of distinct coagulopathic phenotypes in injury: Pathway-specific drivers and implications for individualized treatment. J Trauma Acute Care Surg. 2017 Jun;82(6):1055-1062. PubMed PMID: 28338598

Prior SM, Cohen MJ, Conroy AS, Nelson MF, Kornblith LZ, Howard BM, Butenas S. Correlation between factor (F)XIa, FIXa and tissue factor and trauma severity. J Trauma Acute Care Surg. 2017 Jun;82(6):1073-1079. PubMed PMID: 28328676

Cohen MJ. Translational approaches to coagulopathy after trauma: Towards targeted treatment. PLoS Med. 2017 Jul;14(7):e1002359. PubMed PMID: 28742833

McCully BH, Connelly CR, Fair KA, Holcomb JB, Fox EE, Wade CE, Bulger EM, Schreiber MA. Onset of Coagulation Function Recovery Is Delayed in Severely Injured Trauma Patients with Venous Thromboembolism. J Am Coll Surg. 2017 Jul;225(1):42-51. PubMed PMID: 28315812

Ware LB, Zhao Z, Koyama T, Brown RM, Semler MW, Janz DR, May AK, Fremont RD, Matthay MA, Cohen MJ, Calfee CS. Derivation and validation of a two-biomarker panel for diagnosis of ARDS in patients with severe traumatic injuries. Trauma Surg Acute Care Open. 2017;2(1):e000121. PubMed PMID: 29766112

Asehnoune K, Balogh Z, Citerio G, Cap A, Billiar T, Stocchetti N, Cohen MJ, Pelosi P, Curry N, Gaarder C, Gruen R, Holcomb J, Hunt BJ, Juffermans NP, Maegele M, Midwinter M, Moore FA, O'Dwyer M, Pittet JF, Schöchl H, Schreiber M, Spinella PC, Stanworth S, Winfield R, Brohi K. The research agenda for trauma critical care. Intensive Care Med. 2017 Sep;43(9):1340-1351. PubMed PMID: 28756471

Callcut RA, Moore S, Wakam G, Hubbard AE, Cohen MJ. Finding the signal in the noise: Could social media be utilized for early hospital notification of multiple casualty events?. PLoS One. 2017;12(10):e0186118. PubMed PMID: 28982201

Howard BM, Kornblith LZ, Christie SA, Conroy AS, Nelson MF, Campion EM, Callcut RA, Calfee CS, Lamere BJ, Fadrosh DW, Lynch S, Cohen MJ. Characterizing the gut microbiome in trauma: significant changes in microbial diversity occur early after severe injury. Trauma Surg Acute Care Open. 2017;2(1):e000108. PubMed PMID: 29766103

Campion EM, Juillard C, Knudson MM, Dicker R, Cohen MJ, Mackersie R, Campbell AR, Callcut RA. Reconsidering the Resources Needed for Multiple Casualty Events: Lessons Learned From the Crash of Asiana Airlines Flight 214. JAMA Surg. 2016 Jun 1;151(6):512-7. PubMed PMID: 26764565

Baimukanova G, Miyazawa B, Potter DR, Muench MO, Bruhn R, Gibb SL, Spinella PC, Cap AP, Cohen MJ, Pati S. Platelets regulate vascular endothelial stability: assessing the storage lesion and donor variability of apheresis platelets. Transfusion. 2016 Mar;56 Suppl 1:S65-75. PubMed PMID: 27001364

Howard BM, Kornblith LZ, Cheung CK, Kutcher ME, Miyazawa BY, Vilardi RF, Cohen MJ. Inducing Acute Traumatic Coagulopathy In Vitro: The Effects of Activated Protein C on Healthy Human Whole Blood. PLoS One. 2016;11(3):e0150930. PubMed PMID: 27008408

Hendrickson CM, Howard BM, Kornblith LZ, Conroy AS, Nelson MF, Zhuo H, Liu KD, Manley GT, Matthay MA, Calfee CS, Cohen MJ. The acute respiratory distress syndrome following isolated severe traumatic brain injury. J Trauma Acute Care Surg. 2016 Jun;80(6):989-97. PubMed PMID: 26881489

Rowell SE, Fair KA, Barbosa RR, Watters JM, Bulger EM, Holcomb JB, Cohen MJ, Rahbar MH, Fox EE, Schreiber MA. The Impact of Pre-Hospital Administration of Lactated Ringer's Solution versus Normal Saline in Patients with Traumatic Brain Injury. J Neurotrauma. 2016 Jun 1;33(11):1054-9. PubMed PMID: 26914721

Cohen MJ, Christie SA. New understandings of post injury coagulation and resuscitation. Int J Surg. 2016 Sep;33(Pt B):242-245. PubMed PMID: 27212591

Tominaga GT, Staudenmayer KL, Shafi S, Schuster KM, Savage SA, Ross S, Muskat P, Mowery NT, Miller P, Inaba K, Cohen MJ, Ciesla D, Brown CV, Agarwal S, Aboutanos MB, Utter GH, Crandall M. The American Association for the Surgery of Trauma grading scale for 16 emergency general surgery conditions: Disease-specific criteria characterizing anatomic severity grading. J Trauma Acute Care Surg. 2016 Sep;81(3):593-602. PubMed PMID: 27257696

Deguchi H, Sinha RK, Marchese P, Ruggeri ZM, Zilberman-Rudenko J, McCarty OJT, Cohen MJ, Griffin JH. Prothrombotic skeletal muscle myosin directly enhances prothrombin activation by binding factors Xa and Va. Blood. 2016 Oct 6;128(14):1870-1878. PubMed PMID: 27421960

Kornblith LZ, Howard B, Kunitake R, Redick B, Nelson M, Cohen MJ, Callcut R. Obesity and clotting: Body mass index independently contributes to hypercoagulability after injury. J Trauma Acute Care Surg. 2015 Jan;78(1):30-6; discussion 37-8. PubMed PMID: 25539200

Holcomb JB, Tilley BC, Baraniuk S, Fox EE, Wade CE, Podbielski JM, del Junco DJ, Brasel KJ, Bulger EM, Callcut RA, Cohen MJ, Cotton BA, Fabian TC, Inaba K, Kerby JD, Muskat P, O'Keeffe T, Rizoli S, Robinson BR, Scalea TM, Schreiber MA, Stein DM, Weinberg JA, Callum JL, Hess JR, Matijevic N, Miller CN, Pittet JF, Hoyt DB, Pearson GD, Leroux B, van Belle G. Transfusion of plasma, platelets, and red blood cells in a 1:1:1 vs a 1:1:2 ratio and mortality in patients with severe trauma: the PROPPR randomized clinical trial. JAMA. 2015 Feb 3;313(5):471-82. PubMed PMID: 25647203

Díaz I, Hubbard A, Decker A, Cohen M. Variable importance and prediction methods for longitudinal problems with missing variables. PLoS One. 2015;10(3):e0120031. PubMed PMID: 25815719

Kutcher ME, Howard BM, Sperry JL, Hubbard AE, Decker AL, Cuschieri J, Minei JP, Moore EE, Brownstein BH, Maier RV, Cohen MJ. Evolving beyond the vicious triad: Differential mediation of traumatic coagulopathy by injury, shock, and resuscitation. J Trauma Acute Care Surg. 2015 Mar;78(3):516-23. PubMed PMID: 25710421

Brown JB, Cohen MJ, Minei JP, Maier RV, West MA, Billiar TR, Peitzman AB, Moore EE, Cuschieri J, Sperry JL. Pretrauma center red blood cell transfusion is associated with reduced mortality and coagulopathy in severely injured patients with blunt trauma. Ann Surg. 2015 May;261(5):997-1005. PubMed PMID: 24670858

Pommerening MJ, Goodman MD, Holcomb JB, Wade CE, Fox EE, Del Junco DJ, Brasel KJ, Bulger EM, Cohen MJ, Alarcon LH, Schreiber MA, Myers JG, Phelan HA, Muskat P, Rahbar M, Cotton BA. Clinical gestalt and the prediction of massive transfusion after trauma. Injury. 2015 May;46(5):807-13. PubMed PMID: 25682314

Cohen MJ. Homeless Patients in the ICU: An Observational Propensity-Matched Cohort Study. Crit Care Med. 2015 Jun;43(6):1339-40. PubMed PMID: 25978163

Mann KG, Freeman K. TACTIC: Trans-Agency Consortium for Trauma-Induced Coagulopathy. J Thromb Haemost. 2015 Jun;13 Suppl 1:S63-71. PubMed PMID: 26149052

Privette AR, Evans AE, Moyer JC, Nelson MF, Knudson MM, Mackersie RC, Callcut RA, Cohen MJ. Beyond emergency surgery: redefining acute care surgery. J Surg Res. 2015 Jun 1;196(1):166-71. PubMed PMID: 25799525

Moore SE, Decker A, Hubbard A, Callcut RA, Fox EE, Del Junco DJ, Holcomb JB, Rahbar MH, Wade CE, Schreiber MA, Alarcon LH, Brasel KJ, Bulger EM, Cotton BA, Muskat P, Myers JG, Phelan HA, Cohen MJ. Statistical Machines for Trauma Hospital Outcomes Research: Application to the PRospective, Observational, Multi-Center Major Trauma Transfusion (PROMMTT) Study. PLoS One. 2015;10(8):e0136438. PubMed PMID: 26296088

Hendrickson CM, Dobbins S, Redick BJ, Greenberg MD, Calfee CS, Cohen MJ. Misclassification of acute respiratory distress syndrome after traumatic injury: The cost of less rigorous approaches. J Trauma Acute Care Surg. 2015 Sep;79(3):417-24. PubMed PMID: 26307875

Neal MD, Moore HB, Moore EE, Freeman K, Cohen MJ, Sperry JL, Zuckerbraun BS, Park MS. Clinical assessment of trauma-induced coagulopathy and its contribution to postinjury mortality: A TACTIC proposal. J Trauma Acute Care Surg. 2015 Sep;79(3):490-2. PubMed PMID: 26307885

Pommerening MJ, Rahbar E, Minei K, Holcomb JB, Wade CE, Schreiber MA, Cohen MJ, Underwood SJ, Nelson M, Cotton BA. Splenectomy is associated with hypercoagulable thrombelastography values and increased risk of thromboembolism. Surgery. 2015 Sep;158(3):618-26. PubMed PMID: 26209572

Rahbar E, Cardenas JC, Matijevic N, Del Junco D, Podbielski J, Cohen MJ, Cotton BA, Holcomb JB, Wade CE. Trauma, Time, and Transfusions: A Longitudinal Analysis of Coagulation Markers in Severely Injured Trauma Patients Receiving Modified Whole Blood or Component Blood Products. Shock. 2015 Nov;44(5):417-25. PubMed PMID: 26263433

Howard BM, Miyazawa BY, Dong W, Cedron WJ, Vilardi RF, Ruf W, Cohen MJ. The tissue factor pathway mediates both activation of coagulation and coagulopathy after injury. J Trauma Acute Care Surg. 2015 Dec;79(6):1009-13; discussion 1014. PubMed PMID: 26317815

Moren AM, Hamptom D, Diggs B, Kiraly L, Fox EE, Holcomb JB, Rahbar MH, Brasel KJ, Cohen MJ, Bulger EM, Schreiber MA. Recursive partitioning identifies greater than 4 U of packed red blood cells per hour as an improved massive transfusion definition. J Trauma Acute Care Surg. 2015 Dec;79(6):920-4. PubMed PMID: 26680135

Spitalnik SL, Triulzi D, Devine DV, Dzik WH, Eder AF, Gernsheimer T, Josephson CD, Kor DJ, Luban NL, Roubinian NH, Mondoro T, Welniak LA, Zou S, Glynn S. 2015 proceedings of the National Heart, Lung, and Blood Institute's State of the Science in Transfusion Medicine symposium. Transfusion. 2015 Sep;55(9):2282-90. PubMed PMID: 26260861

Kornblith LZ, Kutcher ME, Redick BJ, Calfee CS, Vilardi RF, Cohen MJ. Fibrinogen and platelet contributions to clot formation: implications for trauma resuscitation and thromboprophylaxis. J Trauma Acute Care Surg. 2014 Feb;76(2):255-6; discussion 262-3. PubMed PMID: 24458031

Sperry J, Cohen MJ. Acute obstruction. Surg Clin North Am. 2014 Feb;94(1):77-96. PubMed PMID: 24267500

Hagemo JS, Stanworth S, Juffermans NP, Brohi K, Cohen M, Johansson PI, Røislien J, Eken T, Næss PA, Gaarder C. Prevalence, predictors and outcome of hypofibrinogenaemia in trauma: a multicentre observational study. Crit Care. 2014 Mar 26;18(2):R52. PubMed PMID: 24666991

Holcomb JB, Fox EE, Scalea TM, Napolitano LM, Albarado R, Gill B, Dunkin BJ, Kirkpatrick AW, Cotton BA, Inaba K, DuBose JJ, Cohen AM, Azizzadeh A, Brenner M, Cohen MJ, Wade CE, Lumsden AB, Andrassy R, Rhee PM, Bass BL, Mattox KL, Britt LD, Eastman AB, Hoyt DB, Rasmussen TE. Current opinion on catheter-based hemorrhage control in trauma patients. J Trauma Acute Care Surg. 2014 Mar;76(3):888-93. PubMed PMID: 24553566

Shafi S, Aboutanos M, Brown CV, Ciesla D, Cohen MJ, Crandall ML, Inaba K, Miller PR, Mowery NT. Measuring anatomic severity of disease in emergency general surgery. J Trauma Acute Care Surg. 2014 Mar;76(3):884-7. PubMed PMID: 24553565

Bulger EM, Maier RV, Sperry J, Joshi M, Henry S, Moore FA, Moldawer LL, Demetriades D, Talving P, Schreiber M, Ham B, Cohen M, Opal S, Segalovich I, Maislin G, Kaempfer R, Shirvan A. A Novel Drug for Treatment of Necrotizing Soft-Tissue Infections: A Randomized Clinical Trial. JAMA Surg. 2014 Jun;149(6):528-36. PubMed PMID: 24740134

Peng J, Zeng J, Cai B, Yang H, Cohen MJ, Chen W, Sun MW, Lu CD, Jiang H. Establishment of quantitative severity evaluation model for spinal cord injury by metabolomic fingerprinting. PLoS One. 2014;9(4):e93736. PubMed PMID: 24727691

Cohen MJ. Acute traumatic coagulopathy: clinical characterization and mechanistic investigation. Thromb Res. 2014 May;133 Suppl 1:S25-7. PubMed PMID: 24759135

Maegele M, Schöchl H, Cohen MJ. An update on the coagulopathy of trauma. Shock. 2014 May;41 Suppl 1:21-5. PubMed PMID: 24192549

Jenkins DH, Rappold JF, Badloe JF, Berséus O, Blackbourne L, Brohi KH, Butler FK, Cap AP, Cohen MJ, Davenport R, DePasquale M, Doughty H, Glassberg E, Hervig T, Hooper TJ, Kozar R, Maegele M, Moore EE, Murdock A, Ness PM, Pati S, Rasmussen T, Sailliol A, Schreiber MA, Sunde GA, van de Watering LM, Ward KR, Weiskopf RB, White NJ, Strandenes G, Spinella PC. Trauma hemostasis and oxygenation research position paper on remote damage control resuscitation: definitions, current practice, and knowledge gaps. Shock. 2014 May;41 Suppl 1:3-12. PubMed PMID: 24430539

Cai B, Sigrid B, Redick B, Jiang H, Sun MW, Yang H, Lu CD, Cohen MJ, Cryer H, Zeng J. Comprehensive level one trauma center could lower in-hospital mortality of severe trauma in China. Biomed Environ Sci. 2014 Jul;27(7):537-43. PubMed PMID: 25073913

Neal MD, Brown JB, Moore EE, Cuschieri J, Maier RV, Minei JP, Billiar TR, Peitzman AB, Cohen MJ, Sperry JL. Prehospital use of nonsteroidal anti-inflammatory drugs (NSAIDs) is associated with a reduced incidence of trauma-induced coagulopathy. Ann Surg. 2014 Aug;260(2):378-82. PubMed PMID: 24424149

Pommerening MJ, Schwartz DA, Cohen MJ, Schreiber MA, del Junco DJ, Camp EA, Wade CE, Holcomb JB, Cotton BA. Hypercoagulability after injury in premenopausal females: a prospective, multicenter study. Surgery. 2014 Aug;156(2):439-47. PubMed PMID: 24953269

Matijevic N, Wang YW, Wade CE, Holcomb JB, Cotton BA, Schreiber MA, Muskat P, Fox EE, Del Junco DJ, Cardenas JC, Rahbar MH, Cohen MJ. Cellular microparticle and thrombogram phenotypes in the Prospective Observational Multicenter Major Trauma Transfusion (PROMMTT) study: correlation with coagulopathy. Thromb Res. 2014 Sep;134(3):652-8. PubMed PMID: 25086657

Kornblith LZ, Howard BM, Cheung CK, Dayter Y, Pandey S, Busch MP, Pati S, Callcut RA, Vilardi RF, Redick BJ, Nelson MF, Cohen MJ. The whole is greater than the sum of its parts: hemostatic profiles of whole blood variants. J Trauma Acute Care Surg. 2014 Dec;77(6):818-27. PubMed PMID: 25051379

Howard BM, Kornblith LZ, Redick BJ, Vilardi RF, Balhotra KS, Crane JM, Forde MR, Nelson MF, Callcut RA, Cohen MJ. The effects of alcohol on coagulation in trauma patients: interpreting thrombelastography with caution. J Trauma Acute Care Surg. 2014 Dec;77(6):865-71; discussion 871-2. PubMed PMID: 25099451

Kutcher ME, Kornblith LZ, Vilardi RF, Redick BJ, Nelson MF, Cohen MJ. The natural history and effect of resuscitation ratio on coagulation after trauma: a prospective cohort study. Ann Surg. 2014 Dec;260(6):1103-11. PubMed PMID: 24846092

Kornblith LZ, Cohen MJ. Response: the whole is greater than the sum of its parts: hemostatic profiles of whole-blood variants. J Trauma Acute Care Surg. 2014 Dec;77(6):1003-4. PubMed PMID: 25423545

Holcomb JB, del Junco DJ, Fox EE, Wade CE, Cohen MJ, Schreiber MA, Alarcon LH, Bai Y, Brasel KJ, Bulger EM, Cotton BA, Matijevic N, Muskat P, Myers JG, Phelan HA, White CE, Zhang J, Rahbar MH. The prospective, observational, multicenter, major trauma transfusion (PROMMTT) study: comparative effectiveness of a time-varying treatment with competing risks. JAMA Surg. 2013 Feb;148(2):127-36. PubMed PMID: 23560283

Callcut RA, Cotton BA, Muskat P, Fox EE, Wade CE, Holcomb JB, Schreiber MA, Rahbar MH, Cohen MJ, Knudson MM, Brasel KJ, Bulger EM, Del Junco DJ, Myers JG, Alarcon LH, Robinson BR. Defining when to initiate massive transfusion: a validation study of individual massive transfusion triggers in PROMMTT patients. J Trauma Acute Care Surg. 2013 Jan;74(1):59-65, 67-8; discussion 66-7. PubMed PMID: 23271078

Brakenridge SC, Henley SS, Kashner TM, Golden RM, Paik DH, Phelan HA, Cohen MJ, Sperry JL, Moore EE, Minei JP, Maier RV, Cuschieri J. Comparing clinical predictors of deep venous thrombosis versus pulmonary embolus after severe injury: a new paradigm for posttraumatic venous thromboembolism?. J Trauma Acute Care Surg. 2013 May;74(5):1231-7; discussion 1237-8. PubMed PMID: 23609272

Brown JB, Cohen MJ, Minei JP, Maier RV, West MA, Billiar TR, Peitzman AB, Moore EE, Cuschieri J, Sperry JL. Goal-directed resuscitation in the prehospital setting: a propensity-adjusted analysis. J Trauma Acute Care Surg. 2013 May;74(5):1207-12; discussion 1212-4. PubMed PMID: 23609269

Grossman AD, Cohen MJ, Manley GT, Butte AJ. Altering physiological networks using drugs: steps towards personalized physiology. BMC Med Genomics. 2013;6 Suppl 2:S7. PubMed PMID: 23819503

Hagemo JS, Næss PA, Johansson P, Windeløv NA, Cohen MJ, Røislien J, Brohi K, Heier HE, Hestnes M, Gaarder C. Evaluation of TEG(®) and RoTEM(®) inter-changeability in trauma patients. Injury. 2013 May;44(5):600-5. PubMed PMID: 23260867

Kutcher ME, Ferguson AR, Cohen MJ. A principal component analysis of coagulation after trauma. J Trauma Acute Care Surg. 2013 May;74(5):1223-9; discussion 1229-30. PubMed PMID: 23609271

Lee TH, McCully BH, Underwood SJ, Cotton BA, Cohen MJ, Schreiber MA. Correlation of conventional thrombelastography and rapid thrombelastography in trauma. Am J Surg. 2013 May;205(5):521-7; discussion 527. PubMed PMID: 23523146

Kornblith LZ, Kutcher ME, Evans AE, Redick BJ, Privette A, Schecter WP, Cohen MJ. The "found down" patient: a diagnostic dilemma. J Trauma Acute Care Surg. 2013 Jun;74(6):1548-52. PubMed PMID: 23694886

Napolitano LM, Cohen MJ, Cotton BA, Schreiber MA, Moore EE. Tranexamic acid in trauma: how should we use it?. J Trauma Acute Care Surg. 2013 Jun;74(6):1575-86. PubMed PMID: 23694890

Barbosa RR, Rowell SE, Fox EE, Holcomb JB, Bulger EM, Phelan HA, Alarcon LH, Myers JG, Brasel KJ, Muskat P, del Junco DJ, Cotton BA, Wade CE, Rahbar MH, Cohen MJ, Schreiber MA. Increasing time to operation is associated with decreased survival in patients with a positive FAST examination requiring emergent laparotomy. J Trauma Acute Care Surg. 2013 Jul;75(1 Suppl 1):S48-52. PubMed PMID: 23778511

Brockamp T, Maegele M, Gaarder C, Goslings JC, Cohen MJ, Lefering R, Joosse P, Naess PA, Skaga NO, Groat T, Eaglestone S, Borgman MA, Spinella PC, Schreiber MA, Brohi K. Comparison of the predictive performance of the BIG, TRISS, and PS09 score in an adult trauma population derived from multiple international trauma registries. Crit Care. 2013 Jul 11;17(4):R134. PubMed PMID: 23844754

del Junco DJ, Holcomb JB, Fox EE, Brasel KJ, Phelan HA, Bulger EM, Schreiber MA, Muskat P, Alarcon LH, Cohen MJ, Cotton BA, Wade CE, Myers JG, Rahbar MH. Resuscitate early with plasma and platelets or balance blood products gradually: findings from the PROMMTT study. J Trauma Acute Care Surg. 2013 Jul;75(1 Suppl 1):S24-30. PubMed PMID: 23778507

del Junco DJ, Fox EE, Camp EA, Rahbar MH, Holcomb JB. Seven deadly sins in trauma outcomes research: an epidemiologic post mortem for major causes of bias. J Trauma Acute Care Surg. 2013 Jul;75(1 Suppl 1):S97-103. PubMed PMID: 23778519

Duchesne JC, Heaney J, Guidry C, McSwain N Jr, Meade P, Cohen M, Schreiber M, Inaba K, Skiada D, Demetriades D, Holcomb J, Wade C, Cotton B. Diluting the benefits of hemostatic resuscitation: a multi-institutional analysis. J Trauma Acute Care Surg. 2013 Jul;75(1):76-82. PubMed PMID: 23778442

Fox EE, Bulger EM, Dickerson AS, del Junco DJ, Klotz P, Podbielski J, Matijevic N, Brasel KJ, Holcomb JB, Schreiber MA, Cotton BA, Phelan HA, Cohen MJ, Myers JG, Alarcon LH, Muskat P, Wade CE, Rahbar MH. Waiver of consent in noninterventional, observational emergency research: the PROMMTT experience. J Trauma Acute Care Surg. 2013 Jul;75(1 Suppl 1):S3-8. PubMed PMID: 23778508

Fuchs PA, del Junco DJ, Fox EE, Holcomb JB, Rahbar MH, Wade CA, Alarcon LH, Brasel KJ, Bulger EM, Cohen MJ, Myers JG, Muskat P, Phelan HA, Schreiber MA, Cotton BA. Purposeful variable selection and stratification to impute missing Focused Assessment with Sonography for Trauma data in trauma research. J Trauma Acute Care Surg. 2013 Jul;75(1 Suppl 1):S75-81. PubMed PMID: 23778515

Hampton DA, Fabricant LJ, Differding J, Diggs B, Underwood S, De La Cruz D, Holcomb JB, Brasel KJ, Cohen MJ, Fox EE, Alarcon LH, Rahbar MH, Phelan HA, Bulger EM, Muskat P, Myers JG, del Junco DJ, Wade CE, Cotton BA, Schreiber MA. Prehospital intravenous fluid is associated with increased survival in trauma patients. J Trauma Acute Care Surg. 2013 Jul;75(1 Suppl 1):S9-15. PubMed PMID: 23778518

Holcomb JB, Fox EE, Zhang X, White N, Wade CE, Cotton BA, del Junco DJ, Bulger EM, Cohen MJ, Schreiber MA, Myers JG, Brasel KJ, Phelan HA, Alarcon LH, Muskat P, Rahbar MH. Cryoprecipitate use in the PROMMTT study. J Trauma Acute Care Surg. 2013 Jul;75(1 Suppl 1):S31-9. PubMed PMID: 23778509

Hubbard A, Munoz ID, Decker A, Holcomb JB, Schreiber MA, Bulger EM, Brasel KJ, Fox EE, del Junco DJ, Wade CE, Rahbar MH, Cotton BA, Phelan HA, Myers JG, Alarcon LH, Muskat P, Cohen MJ. Time-dependent prediction and evaluation of variable importance using superlearning in high-dimensional clinical data. J Trauma Acute Care Surg. 2013 Jul;75(1 Suppl 1):S53-60. PubMed PMID: 23778512

Rahbar E, Fox EE, del Junco DJ, Harvin JA, Holcomb JB, Wade CE, Schreiber MA, Rahbar MH, Bulger EM, Phelan HA, Brasel KJ, Alarcon LH, Myers JG, Cohen MJ, Muskat P, Cotton BA. Early resuscitation intensity as a surrogate for bleeding severity and early mortality in the PROMMTT study. J Trauma Acute Care Surg. 2013 Jul;75(1 Suppl 1):S16-23. PubMed PMID: 23778506

Rahbar MH, del Junco DJ, Huang H, Ning J, Fox EE, Zhang X, Schreiber MA, Brasel KJ, Bulger EM, Wade CE, Cotton BA, Phelan HA, Cohen MJ, Myers JG, Alarcon LH, Muskat P, Holcomb JB. A latent class model for defining severe hemorrhage: experience from the PROMMTT study. J Trauma Acute Care Surg. 2013 Jul;75(1 Suppl 1):S82-8. PubMed PMID: 23778516

Robinson BR, Cotton BA, Pritts TA, Branson R, Holcomb JB, Muskat P, Fox EE, Wade CE, del Junco DJ, Bulger EM, Cohen MJ, Schreiber MA, Myers JG, Brasel KJ, Phelan HA, Alarcon LH, Rahbar MH, Callcut RA. Application of the Berlin definition in PROMMTT patients: the impact of resuscitation on the incidence of hypoxemia. J Trauma Acute Care Surg. 2013 Jul;75(1 Suppl 1):S61-7. PubMed PMID: 23778513

Trickey AW, Fox EE, del Junco DJ, Ning J, Holcomb JB, Brasel KJ, Cohen MJ, Schreiber MA, Bulger EM, Phelan HA, Alarcon LH, Myers JG, Muskat P, Cotton BA, Wade CE, Rahbar MH. The impact of missing trauma data on predicting massive transfusion. J Trauma Acute Care Surg. 2013 Jul;75(1 Suppl 1):S68-74. PubMed PMID: 23778514

Wade CE, del Junco DJ, Fox EE, Cotton BA, Cohen MJ, Muskat P, Schreiber MA, Rahbar MH, Sauer RM, Brasel KJ, Bulger EM, Myers JG, Phelan HA, Alarcon LH, Holcomb JB. Do-not-resuscitate orders in trauma patients may bias mortality-based effect estimates: an evaluation using the PROMMTT study. J Trauma Acute Care Surg. 2013 Jul;75(1 Suppl 1):S89-96. PubMed PMID: 23778517

Cripps MW, Kutcher ME, Daley A, McCreery RC, Greenberg MD, Cachola LM, Redick BJ, Nelson MF, Cohen MJ. Cause and timing of death in massively transfused trauma patients. J Trauma Acute Care Surg. 2013 Aug;75(2 Suppl 2):S255-62. PubMed PMID: 23883917

Kutcher ME, Kornblith LZ, Narayan R, Curd V, Daley AT, Redick BJ, Nelson MF, Fiebig EW, Cohen MJ. A paradigm shift in trauma resuscitation: evaluation of evolving massive transfusion practices. JAMA Surg. 2013 Sep;148(9):834-40. PubMed PMID: 23864019

Napolitano LM, Cohen MJ, Cotton BA, Schreiber MA, Moore EE. Re: Is viscoelastic evidence of hyperfibrinolysis the ideal indicator for tranexamic acid administration in trauma?. J Trauma Acute Care Surg. 2013 Oct;75(4):743-4. PubMed PMID: 24064893

Kornblith LZ, Kutcher ME, Callcut RA, Redick BJ, Hu CK, Cogbill TH, Baker CC, Shapiro ML, Burlew CC, Kaups KL, DeMoya MA, Haan JM, Koontz CH, Zolin SJ, Gordy SD, Shatz DV, Paul DB, Cohen MJ. Mechanical ventilation weaning and extubation after spinal cord injury: a Western Trauma Association multicenter study. J Trauma Acute Care Surg. 2013 Dec;75(6):1060-9; discussion 1069-70. PubMed PMID: 24256682

Christie JD, Wurfel MM, Feng R, O'Keefe GE, Bradfield J, Ware LB, Christiani DC, Calfee CS, Cohen MJ, Matthay M, Meyer NJ, Kim C, Li M, Akey J, Barnes KC, Sevransky J, Lanken PN, May AK, Aplenc R, Maloney JP, Hakonarson H. Genome wide association identifies PPFIA1 as a candidate gene for acute lung injury risk following major trauma. PLoS One. 2012;7(1):e28268. PubMed PMID: 22295056

Cohen MJ, Call M, Nelson M, Calfee CS, Esmon CT, Brohi K, Pittet JF. Critical role of activated protein C in early coagulopathy and later organ failure, infection and death in trauma patients. Ann Surg. 2012 Feb;255(2):379-85. PubMed PMID: 22133894

Minei JP, Cuschieri J, Sperry J, Moore EE, West MA, Harbrecht BG, O'Keefe GE, Cohen MJ, Moldawer LL, Tompkins RG, Maier RV. The changing pattern and implications of multiple organ failure after blunt injury with hemorrhagic shock. Crit Care Med. 2012 Apr;40(4):1129-35. PubMed PMID: 22020243

Rahbar MH, Fox EE, del Junco DJ, Cotton BA, Podbielski JM, Matijevic N, Cohen MJ, Schreiber MA, Zhang J, Mirhaji P, Duran SJ, Reynolds RJ, Benjamin-Garner R, Holcomb JB. Coordination and management of multicenter clinical studies in trauma: Experience from the PRospective Observational Multicenter Major Trauma Transfusion (PROMMTT) Study. Resuscitation. 2012 Apr;83(4):459-64. PubMed PMID: 22001613

Cohen MJ. Use of models in identification and prediction of physiology in critically ill surgical patients. Br J Surg. 2012 Apr;99(4):487-93. PubMed PMID: 22287099

Howard BM, Daley AT, Cohen MJ. Prohemostatic interventions in trauma: resuscitation-associated coagulopathy, acute traumatic coagulopathy, hemostatic resuscitation, and other hemostatic interventions. Semin Thromb Hemost. 2012 Apr;38(3):250-8. PubMed PMID: 22467527

Neal MD, Hoffman MK, Cuschieri J, Minei JP, Maier RV, Harbrecht BG, Billiar TR, Peitzman AB, Moore EE, Cohen MJ, Sperry JL. Crystalloid to packed red blood cell transfusion ratio in the massively transfused patient: when a little goes a long way. J Trauma Acute Care Surg. 2012 Apr;72(4):892-8. PubMed PMID: 22491601

Frith D, Cohen MJ, Brohi K. Animal models of trauma-induced coagulopathy. Thromb Res. 2012 May;129(5):551-6. PubMed PMID: 22197179

Laroche M, Kutcher ME, Huang MC, Cohen MJ, Manley GT. Coagulopathy after traumatic brain injury. Neurosurgery. 2012 Jun;70(6):1334-45. PubMed PMID: 22307074

Kutcher ME, Cripps MW, McCreery RC, Crane IM, Greenberg MD, Cachola LM, Redick BJ, Nelson MF, Cohen MJ. Criteria for empiric treatment of hyperfibrinolysis after trauma. J Trauma Acute Care Surg. 2012 Jul;73(1):87-93. PubMed PMID: 22743377

Kutcher ME, Redick BJ, McCreery RC, Crane IM, Greenberg MD, Cachola LM, Nelson MF, Cohen MJ. Characterization of platelet dysfunction after trauma. J Trauma Acute Care Surg. 2012 Jul;73(1):13-9. PubMed PMID: 22743367

Brown JB, Cohen MJ, Minei JP, Maier RV, West MA, Billiar TR, Peitzman AB, Moore EE, Cushieri J, Sperry JL. Debunking the survival bias myth: characterization of mortality during the initial 24 hours for patients requiring massive transfusion. J Trauma Acute Care Surg. 2012 Aug;73(2):358-64; discussion 364. PubMed PMID: 22846940

Cohen MJ. Towards hemostatic resuscitation: the changing understanding of acute traumatic biology, massive bleeding, and damage-control resuscitation. Surg Clin North Am. 2012 Aug;92(4):877-91, viii. PubMed PMID: 22850152

Burlew CC, Moore EE, Cuschieri J, Jurkovich GJ, Codner P, Nirula R, Millar D, Cohen MJ, Kutcher ME, Haan J, MacNew HG, Ochsner G, Rowell SE, Truitt MS, Moore FO, Pieracci FM, Kaups KL. Who should we feed? Western Trauma Association multi-institutional study of enteral nutrition in the open abdomen after injury. J Trauma Acute Care Surg. 2012 Dec;73(6):1380-7; discussion 1387-8. PubMed PMID: 22835999

Brown JB, Cohen MJ, Minei JP, Maier RV, West MA, Billiar TR, Peitzman AB, Moore EE, Cuschieri J, Sperry JL. Characterization of acute coagulopathy and sexual dimorphism after injury: females and coagulopathy just do not mix. J Trauma Acute Care Surg. 2012 Dec;73(6):1395-400. PubMed PMID: 23064602

Kutcher ME, Xu J, Vilardi RF, Ho C, Esmon CT, Cohen MJ. Extracellular histone release in response to traumatic injury: implications for a compensatory role of activated protein C. J Trauma Acute Care Surg. 2012 Dec;73(6):1389-94. PubMed PMID: 23188230

Knudson MM, Cohen MJ, Reidy R, Jaeger S, Bacchetti P, Jin C, Wade CE, Holcomb JB. Trauma, transfusions, and use of recombinant factor VIIa: A multicenter case registry report of 380 patients from the Western Trauma Association. J Am Coll Surg. 2011 Jan;212(1):87-95. PubMed PMID: 21115374

Xu W, Seok J, Mindrinos MN, Schweitzer AC, Jiang H, Wilhelmy J, Clark TA, Kapur K, Xing Y, Faham M, Storey JD, Moldawer LL, Maier RV, Tompkins RG, Wong WH, Davis RW, Xiao W. Human transcriptome array for high-throughput clinical studies. Proc Natl Acad Sci U S A. 2011 Mar 1;108(9):3707-12. PubMed PMID: 21317363

Cohen MJ, West M. Acute traumatic coagulopathy: from endogenous acute coagulopathy to systemic acquired coagulopathy and back. J Trauma. 2011 May;70(5 Suppl):S47-9. PubMed PMID: 21841573

Meyer NJ, Li M, Feng R, Bradfield J, Gallop R, Bellamy S, Fuchs BD, Lanken PN, Albelda SM, Rushefski M, Aplenc R, Abramova H, Atochina-Vasserman EN, Beers MF, Calfee CS, Cohen MJ, Pittet JF, Christiani DC, O'Keefe GE, Ware LB, May AK, Wurfel MM, Hakonarson H, Christie JD. ANGPT2 genetic variant is associated with trauma-associated acute lung injury and altered plasma angiopoietin-2 isoform ratio. Am J Respir Crit Care Med. 2011 May 15;183(10):1344-53. PubMed PMID: 21257790

Calfee CS, Matthay MA, Eisner MD, Benowitz N, Call M, Pittet JF, Cohen MJ. Active and passive cigarette smoking and acute lung injury after severe blunt trauma. Am J Respir Crit Care Med. 2011 Jun 15;183(12):1660-5. PubMed PMID: 21471091

Barbosa RR, Rowell SE, Sambasivan CN, Diggs BS, Spinella PC, Schreiber MA, Holcomb JB, Wade CE, Brasel KJ, Vercruysse G, MacLeod J, Dutton RP, Hess JR, Duchesne JC, McSwain NE, Muskat P, Johannigamn J, Cryer HM, Tillou A, Cohen MJ, Pittet JF, Knudson P, De Moya MA, Schreiber MA, Tieu B, Brundage S, Napolitano LM, Brunsvold M, Sihler KC, Beilman G, Peitzman AB, Zenait MS, Sperry J, Alarcon L, Croce MA, Minei JP, Kozar R, Gonzalez EA, Stewart RM, Cohn SM, Mickalek JE, Bulger EM, Cotton BA, Nunez TC, Ivatury R, Meredith JW, Pomper GJ, Marin B. A predictive model for mortality in massively transfused trauma patients. J Trauma. 2011 Aug;71(2 Suppl 3):S370-4. PubMed PMID: 21814106

Brown LM, Call MS, Margaret Knudson M, Cohen MJ, Holcomb JB, Wade CE, Brasel KJ, Vercruysse G, MacLeod J, Dutton RP, Hess JR, Duchesne JC, McSwain NE, Muskat P, Johannigamn J, Cryer HM, Tillou A, Pittet JF, De Moya MA, Schreiber MA, Tieu B, Brundage S, Napolitano LM, Brunsvold M, Brunsvold M, Beilman G, Peitzman AB, Zenait MS, Sperry J, Alarcon L, Croce MA, Minei JP, Kozar R, Gonzalez EA, Stewart RM, Cohn SM, Mickalek JE, Bulger EM, Cotton BA, Nunez TC, Ivatury R, Meredith JW, Miller P, Pomper GJ, Marin B. A normal platelet count may not be enough: the impact of admission platelet count on mortality and transfusion in severely injured trauma patients. J Trauma. 2011 Aug;71(2 Suppl 3):S337-42. PubMed PMID: 21814101

Holcomb JB, Wade CE, Brasel KJ, Vercruysse G, MacLeod J, Dutton RP, Hess JR, Duchesne JC, McSwain NE, Muskat P, Johannigamn J, Cryer HM, Tillou A, Cohen MJ, Pittet JF, Knudson P, De Moya MA, Schreiber MA, Tieu B, Brundage S, Napolitano LM, Brunsvold M, Sihler KC, Beilman G, Peitzman AB, Zenait MS, Sperry J, Alarcon L, Croce MA, Minei JP, Kozar R, Gonzalez EA, Stewart RM, Cohn SM, Mickalek JE, Bulger EM, Cotton BA, Nunez TC, Ivatury R, Meredith JW, Miller P, Pomper GJ, Marin B. Defining present blood component transfusion practices in trauma patients: papers from the Trauma Outcomes Group. J Trauma. 2011 Aug;71(2 Suppl 3):S315-7. PubMed PMID: 21814098

Holcomb JB, Zarzabal LA, Michalek JE, Kozar RA, Spinella PC, Perkins JG, Matijevic N, Dong JF, Pati S, Wade CE, Holcomb JB, Wade CE, Cotton BA, Kozar RA, Brasel KJ, Vercruysse GA, MacLeod JB, Dutton RP, Hess JR, Duchesne JC, McSwain NE, Muskat PC, Johannigamn JA, Cryer HM, Tillou A, Cohen MJ, Pittet JF, Knudson P, DeMoya MA, Schreiber MA, Tieu BH, Brundage SI, Napolitano LM, Brunsvold ME, Sihler KC, Beilman GJ, Peitzman AB, Zenati MS, Sperry JL, Alarcon LH, Croce MA, Minei JP, Steward RM, Cohn SM, Michalek JE, Bulger EM, Nunez TC, Ivatury RR, Meredith JW, Miller PR, Pomper GJ, Marin B. Increased platelet:RBC ratios are associated with improved survival after massive transfusion. J Trauma. 2011 Aug;71(2 Suppl 3):S318-28. PubMed PMID: 21814099

Brasel KJ, Vercruysse G, Spinella PC, Wade CE, Blackbourne LH, Borgman MA, Zarzabal LA, Du F, Perkins JG, Maegele M, Schreiber M, Hess JR, Jastrow KM 3rd, Gonzalez EA, Holcomb JB, Kozar R, Brasel KJ, Vercruysse G, MacLeod J, Dutton RP, Duchesne JC, McSwain NE, Muskat P, Johannigamn J, Cryer HM, Cryer HM, Pittet JF, Knudson P, De Moya MA, Tieu B, Brundage S, Napolitano LM, Brunsvold M, Sihler KC, Beilman G, Peitzman AB, Zenait MS, Sperry J, Alarcon L, Croce MA, Minei JP, Stewart RM, Cohn SM, Mickalek JE, Bulger EM, Cotton BA, Nunez TC, Ivatury R, Meredith JW, Miller P, Pomper GJ, Marin B. The association of blood component use ratios with the survival of massively transfused trauma patients with and without severe brain injury. J Trauma. 2011 Aug;71(2 Suppl 3):S343-52. PubMed PMID: 21814102

Rowell SE, Barbosa RR, Diggs BS, Schreiber MA, Holcomb JB, Wade CE, Brasel KJ, Vercruysse G, MacLeod J, Dutton RP, Hess JR, Duchesne JC, McSwain NE, Muskat P, Johannigamn J, Cryer HM, Tillou A, Cohen MJ, Pittet JF, Knudson P, De Moya MA, Schreiber MA, Tieu B, Brundage S, Napolitano LM, Brunsvold M, Sihler KC, Beilman G, Peitzman AB, Zenait MS, Sperry J, Alarcon L, Croce MA, Minei JP, Kozar R, Gonzalez EA, Stewart RM, Cohn SM, Mickalek JE, Bulger EM, Cotton BA, Nunez TC, Ivatury R, Meredith JW, Miller P, Pomper GJ, Marin B. Effect of high product ratio massive transfusion on mortality in blunt and penetrating trauma patients. J Trauma. 2011 Aug;71(2 Suppl 3):S353-7. PubMed PMID: 21814103

Barbosa RR, Rowell SE, Diggs BS, Schreiber MA, Holcomb JB, Wade CE, Brasel KJ, Vercruysse G, MacLeod J, Dutton RP, Hess JR, Duchesne JC, McSwain NE, Muskat P, Johannigamn J, Cryer HM, Tillou A, Cohen MJ, Pittet JF, Knudson P, De Moya MA, Schreiber MA, Tieu B, Brundage S, Napolitano LM, Brunsvold M, Sihler KC, Beilman G, Peitzman AB, Zenait MS, Sperry J, Alarcon L, Croce MA, Minei JP, Kozar R, Gonzalez EA, Stewart RM, Cohn SM, Mickalek JE, Bulger EM, Cotton BA, Nunez TC, Ivatury R, Meredith JW, Miller P, Pomper GJ, Marin B. Profoundly abnormal initial physiologic and biochemical data cannot be used to determine futility in massively transfused trauma patients. J Trauma. 2011 Aug;71(2 Suppl 3):S364-9. PubMed PMID: 21814105

Rowell SE, Barbosa RR, Allison CE, Van PY, Schreiber MA, Holcomb JB, Wade CE, Brasel KJ, Vercruysse G, MacLeod J, Dutton RP, Hess JR, Duchesne JC, McSwain NE, Muskat P, Johannigamn J, Cryer HM, Tillou A, Cohen MJ, Pittet JF, Knudson P, De Moya MA, Schreiber MA, Tieu B, Brundage S, Napolitano LM, Brunsvold M, Sihler KC, Beilman G, Peitzman AB, Zenait MS, Sperry J, Alarcon L, Croce MA, Minei JP, Kozar R, Gonzalez EA, Stewart RM, Cohn SM, Mickalek JE, Bulger EM, Cotton BA, Nunez TC, Ivatury R, Meredith JW, Pomper P, Pomper GJ, Marin B. Gender-based differences in mortality in response to high product ratio massive transfusion. J Trauma. 2011 Aug;71(2 Suppl 3):S375-9. PubMed PMID: 21814107

Spoerke N, Michalek J, Schreiber M, Brasel KJ, Vercruysse G, MacLeod J, Dutton RP, Duchesne JC, McSwain NE, Muskat P, Johannigamn J, Cryer HM, Tillou A, Cohen MJ, Pittet JF, Knudson P, De Moya MA, Tieu B, Brundage S, Napolitano LM, Brunsvold M, Sihler KC, Peitzman AB, Zenait MS, Sperry J, Alarcon L, Croce MA, Minei JP, Stewart RM, Cohn SM, Mickalek JE, Bulger EM, Cotton BA, Nunez TC, Ivatury R, Meredith JW, Miller P, Pomper GJ, Marin B. Crystalloid resuscitation improves survival in trauma patients receiving low ratios of fresh frozen plasma to packed red blood cells. J Trauma. 2011 Aug;71(2 Suppl 3):S380-3. PubMed PMID: 21814108

Rowell SE, Barbosa RR, Diggs BS, Schreiber MA, Holcomb JB, Wade CE, Brasel KJ, Vercruysse G, MacLeod J, Dutton RP, Hess JR, Duchesne JC, McSwain NE, Muskat P, Johannigamn J, Cryer HM, Tillou A, Cohen MJ, Pittet JF, Knudson P, De Moya MA, Schreiber MA, Tieu B, Brundage S, Napolitano LM, Brunsvold M, Sihler KC, Beilman G, Peitzman AB, Zenait MS, Sperry J, Alarcon L, Croce MA, Minei JP, Kozar R, Gonzalez EA, Stewart RM, Cohn SM, Mickalek JE, Bulger EM, Cotton BA, Nunez TC, Ivatury R, Meredith JW, Miller P, Pomper J, Marin B. Specific abbreviated injury scale values are responsible for the underestimation of mortality in penetrating trauma patients by the injury severity score. J Trauma. 2011 Aug;71(2 Suppl 3):S384-8. PubMed PMID: 21814109

Bir N, Lafargue M, Howard M, Goolaerts A, Roux J, Carles M, Cohen MJ, Iles KE, Fernández JA, Griffin JH, Pittet JF. Cytoprotective-selective activated protein C attenuates Pseudomonas aeruginosa-induced lung injury in mice. Am J Respir Cell Mol Biol. 2011 Sep;45(3):632-41. PubMed PMID: 21257925

Knudson MM, Gomez D, Haas B, Cohen MJ, Nathens AB. Three thousand seven hundred thirty-eight posttraumatic pulmonary emboli: a new look at an old disease. Ann Surg. 2011 Oct;254(4):625-32. PubMed PMID: 21869675

Kutcher ME, Pepper MB, Morabito D, Sunjaya D, Knudson MM, Cohen MJ. Finding the sweet spot: identification of optimal glucose levels in critically injured patients. J Trauma. 2011 Nov;71(5):1108-14. PubMed PMID: 22071916

Call MS, Kutcher ME, Izenberg RA, Singh T, Cohen MJ. Spinal cord injury: outcomes of ventilatory weaning and extubation. J Trauma. 2011 Dec;71(6):1673-9. PubMed PMID: 21768893

Sambasivan CN, Kunio NR, Nair PV, Zink KA, Michalek JE, Holcomb JB, Schreiber MA, Wade CE, Brasel KJ, Vercruysse G, MacLeod J, Dutton RP, Hess JR, Duchesne JC, McSwain NE, Muskat P, Johannigamn J, Cryer HM, Tillou A, Cohen MJ, Pittet JF, Knudson P, De Moya MA, Tieu B, Brundage S, Napolitano LM, Brunsvold M, Sihler KC, Beilman G, Peitzman AB, Zenait MS, Sperry J, Alarcon L, Croce MA, Minei JP, Kozar R, Gonzalez EA, Stewart RM, Cohn SM, Bulger EM, Cotton BA, Nunez TC, Ivatury R, Meredith JW, Miller P, Pomper GJ, Marin B. High ratios of plasma and platelets to packed red blood cells do not affect mortality in nonmassively transfused patients. J Trauma. 2011 Aug;71(2 Suppl 3):S329-36. PubMed PMID: 21814100

Cohen MJ, Carles M, Brohi K, Calfee CS, Rahn P, Call MS, Chesebro BB, West MA, Pittet JF. Early release of soluble receptor for advanced glycation endproducts after severe trauma in humans. J Trauma. 2010 Jun;68(6):1273-8. PubMed PMID: 20539169

Cohen MJ, Serkova NJ, Wiener-Kronish J, Pittet JF, Niemann CU. 1H-NMR-based metabolic signatures of clinical outcomes in trauma patients--beyond lactate and base deficit. J Trauma. 2010 Jul;69(1):31-40. PubMed PMID: 20622576

Frith D, Goslings JC, Gaarder C, Maegele M, Cohen MJ, Allard S, Johansson PI, Stanworth S, Thiemermann C, Brohi K. Definition and drivers of acute traumatic coagulopathy: clinical and experimental investigations. J Thromb Haemost. 2010 Sep;8(9):1919-25. PubMed PMID: 20553376

Stanworth SJ, Morris TP, Gaarder C, Goslings JC, Maegele M, Cohen MJ, König TC, Davenport RA, Pittet JF, Johansson PI, Allard S, Johnson T, Brohi K. Reappraising the concept of massive transfusion in trauma. Crit Care. 2010;14(6):R239. PubMed PMID: 21192812

Lord C, Ozgediz D, Cohen MJ. Image of the month. Gastrointestinal stromal tumor. Arch Surg. 2009 Jan;144(1):87-88. PubMed PMID: 19153331

Morshed S, Miclau T 3rd, Bembom O, Cohen M, Knudson MM, Colford JM Jr. Delayed internal fixation of femoral shaft fracture reduces mortality among patients with multisystem trauma. J Bone Joint Surg Am. 2009 Jan;91(1):3-13. PubMed PMID: 19122073

Wan JJ, Cohen MJ, Rosenthal G, Haitsma IK, Morabito DJ, Derugin N, Knudson MM, Manley GT. Refining resuscitation strategies using tissue oxygen and perfusion monitoring in critical organ beds. J Trauma. 2009 Feb;66(2):353-7. PubMed PMID: 19204507

Cohen MJ, Brohi K, Calfee CS, Rahn P, Chesebro BB, Christiaans SC, Carles M, Howard M, Pittet JF. Early release of high mobility group box nuclear protein 1 after severe trauma in humans: role of injury severity and tissue hypoperfusion. Crit Care. 2009;13(6):R174. PubMed PMID: 19887013

Chang CK, Chuter TA, Niemann CU, Shlipak MG, Cohen MJ, Reilly LM, Hiramoto JS. Systemic inflammation, coagulopathy, and acute renal insufficiency following endovascular thoracoabdominal aortic aneurysm repair. J Vasc Surg. 2009 May;49(5):1140-6. PubMed PMID: 19394543

Grossman AD, Cohen MJ, Manley GT, Butte AJ. Infection in the intensive care unit alters physiological networks. BMC Bioinformatics. 2009 Sep 17;10 Suppl 9:S4. PubMed PMID: 19761574

Chesebro BB, Rahn P, Carles M, Esmon CT, Xu J, Brohi K, Frith D, Pittet JF, Cohen MJ. Increase in activated protein C mediates acute traumatic coagulopathy in mice. Shock. 2009 Dec;32(6):659-65. PubMed PMID: 19333141

Cohen MJ, Bir N, Rahn P, Dotson R, Brohi K, Chesebro BB, Mackersie R, Carles M, Wiener-Kronish J, Pittet JF. Protein C depletion early after trauma increases the risk of ventilator-associated pneumonia. J Trauma. 2009 Dec;67(6):1176-81. PubMed PMID: 20009664

Ganter MT, Cohen MJ, Brohi K, Chesebro BB, Staudenmayer KL, Rahn P, Christiaans SC, Bir ND, Pittet JF. Angiopoietin-2, marker and mediator of endothelial activation with prognostic significance early after trauma?. Ann Surg. 2008 Feb;247(2):320-6. PubMed PMID: 18216540

Knudson MM, Khaw L, Bullard MK, Dicker R, Cohen MJ, Staudenmayer K, Sadjadi J, Howard S, Gaba D, Krummel T. Trauma training in simulation: translating skills from SIM time to real time. J Trauma. 2008 Feb;64(2):255-63; discussion 263-4. PubMed PMID: 18301184

Rosenthal G, Morabito D, Cohen M, Roeytenberg A, Derugin N, Panter SS, Knudson MM, Manley G. Use of hemoglobin-based oxygen-carrying solution-201 to improve resuscitation parameters and prevent secondary brain injury in a swine model of traumatic brain injury and hemorrhage: laboratory investigation. J Neurosurg. 2008 Mar;108(3):575-87. PubMed PMID: 18312106

Brohi K, Cohen MJ, Ganter MT, Schultz MJ, Levi M, Mackersie RC, Pittet JF. Acute coagulopathy of trauma: hypoperfusion induces systemic anticoagulation and hyperfibrinolysis. J Trauma. 2008 May;64(5):1211-7; discussion 1217. PubMed PMID: 18469643

Cohen MJ, Carroll C, He LK, Muthu K, Gamelli RL, Jones SB, Shankar R. Severity of burn injury and sepsis determines the cytokine responses of bone marrow progenitor-derived macrophages. J Trauma. 2007 Apr;62(4):858-67. PubMed PMID: 17426540

Brohi K, Cohen MJ, Ganter MT, Matthay MA, Mackersie RC, Pittet JF. Acute traumatic coagulopathy: initiated by hypoperfusion: modulated through the protein C pathway?. Ann Surg. 2007 May;245(5):812-8. PubMed PMID: 17457176

Ganter MT, Brohi K, Cohen MJ, Shaffer LA, Walsh MC, Stahl GL, Pittet JF. Role of the alternative pathway in the early complement activation following major trauma. Shock. 2007 Jul;28(1):29-34. PubMed PMID: 17510601

Cohen MJ, Brohi K, Ganter MT, Manley GT, Mackersie RC, Pittet JF. Early coagulopathy after traumatic brain injury: the role of hypoperfusion and the protein C pathway. J Trauma. 2007 Dec;63(6):1254-61; discussion 1261-2. PubMed PMID: 18212647

Brohi K, Cohen MJ, Davenport RA. Acute coagulopathy of trauma: mechanism, identification and effect. Curr Opin Crit Care. 2007 Dec;13(6):680-5. PubMed PMID: 17975390

Ikossi DG, Knudson MM, Morabito DJ, Cohen MJ, Wan JJ, Khaw L, Stewart CJ, Hemphill C, Manley GT. Continuous muscle tissue oxygenation in critically injured patients: a prospective observational study. J Trauma. 2006 Oct;61(4):780-8; discussion 788-90. PubMed PMID: 17033541

Cohen MJ, Schecter WP. Perioperative pain control: a strategy for management. Surg Clin North Am. 2005 Dec;85(6):1243-57, xi. PubMed PMID: 16326205

Cohen MJ, Shankar R, Stevenson J, Fernandez R, Gamelli RL, Jones SB. Bone marrow norepinephrine mediates development of functionally different macrophages after thermal injury and sepsis. Ann Surg. 2004 Jul;240(1):132-41. PubMed PMID: 15213629

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Mitchell Cohen, MD
Professor, Surgery-GI, Trauma, and Endocrine Surgery

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Mitchell Cohen, MD Professor, Surgery-GI, Trauma, and Endocrine Surgery

Professional Titles

Publications

Practice Locations

Specialty Information

General Information

SOM Resources

CU Resources

Contact Us

Mitchell Cohen, MD
Professor, Surgery-GI, Trauma, and Endocrine Surgery