Jaime Belkind-Gerson, MD, MSc

Publications

• Cheng LS, Hotta R, Graham HK, Belkind-Gerson J, Nagy N, Goldstein AM. Postnatal human enteric neuronal progenitors can migrate, differentiate, and proliferate in embryonic and postnatal aganglionic gut environments. Pediatr Res. 2017 Jan 6. [Epub ahead of print] PubMed PMID: 28060794
• Zar-Kessler CA, Belkind-Gerson J, Bender S, Kuo BM. Treatment of Functional Abdominal Pain with Antidepressants: Benefits, Side Effects and the Gastroenterologist's Role. J Pediatr Gastroenterol Nutr. 2016 Sep 16. [Epub ahead of print] PubMed PMID: 27642783
• Burns AJ, Goldstein AM, Newgreen DF, Stamp L, Schäfer KH, Metzger M, Hotta R, Young HM, Andrews PW, Thapar N, Belkind-Gerson J, Bondurand N, Bornstein JC, Chan WY, Cheah K, Gershon MD, Heuckeroth RO, Hofstra RM, Just L, Kapur RP, King SK, McCann CJ, Nagy N, Ngan E, Obermayr F, Pachnis V, Pasricha PJ, Sham MH, Tam P, Vanden Berghe P. White paper on guidelines concerning enteric nervous system stem cell therapy for enteric neuropathies. Dev Biol. 2016 Sep 15;417(2):229-51. PubMed PMID: 27059883
• Hotta R, Cheng LS, Graham HK, Nagy N, Belkind-Gerson J, Mattheolabakis G, Amiji MM, Goldstein AM. Delivery of enteric neural progenitors with 5-HT4 agonist-loaded nanoparticles and thermosensitive hydrogel enhances cell proliferation and differentiation following transplantation in vivo. Biomaterials. 2016 May;88:1-11. PubMed PMID: 26922325
• Belkind-Gerson J, Hotta R, Whalen M, Nayyar N, Nagy N, Cheng L, Zuckerman A, Goldstein AM, Dietrich J. Engraftment of enteric neural progenitor cells into the injured adult brain. BMC Neurosci. 2016 Jan 25;17:5. PubMed PMID: 26810757
• Hotta R, Cheng LS, Graham HK, Pan W, Nagy N, Belkind-Gerson J, Goldstein AM. Isogenic enteric neural progenitor cells can replace missing neurons and glia in mice with Hirschsprung disease. Neurogastroenterol Motil. 2016 Apr;28(4):498-512. PubMed PMID: 26685978
• Tran K, Staller K, Macklin E, Goldstein A, Belkind-Gerson J, Kuo B. Need for Rectal Biopsy for Childhood Constipation Predicts Severity of Illness and Need for Laxatives. J Pediatr Gastroenterol Nutr. 2016 Jun;62(6):834-9. PubMed PMID: 26551318
• Zar-Kessler CAM, Belkind-Gerson J, Bender S, Kuo BM. Treatment of Functional Abdominal Pain With Antidepressants: Benefits, Adverse Effects, and the Gastroenterologist's Role. J Pediatr Gastroenterol Nutr. 2017 Jul;65(1):16-21. PubMed PMID: 28644344
• Belkind-Gerson J, Graham HK, Reynolds J, Hotta R, Nagy N, Cheng L, Kamionek M, Shi HN, Aherne CM, Goldstein AM. Colitis promotes neuronal differentiation of Sox2 and PLP1 enteric cells. Sci Rep. 2017 May 31;7(1):2525. PubMed PMID: 28566702
• Cheng LS, Hotta R, Graham HK, Belkind-Gerson J, Nagy N, Goldstein AM. Postnatal human enteric neuronal progenitors can migrate, differentiate, and proliferate in embryonic and postnatal aganglionic gut environments. Pediatr Res. 2017 May;81(5):838-846. PubMed PMID: 28060794
• Zar-Kessler C, Kuo B, Belkind-Gerson J. Botulinum toxin injection for childhood constipation is safe and can be effective regardless of anal sphincter dynamics. J Pediatr Surg. 2018 Apr;53(4):693-697. PubMed PMID: 29395154
• Zar-Kessler CAM, Belkind-Gerson J, Bender S, Kuo BM. Treatment of Functional Abdominal Pain With Antidepressants: Benefits, Adverse Effects, and the Gastroenterologist's Role. J Pediatr Gastroenterol Nutr. 2017 Jul;65(1):16-21. PubMed PMID: 28644344
• Wyllie: Pediatric Gastrointestinal and Liver Disease. Elsevier.
• Pediatric Neurogastroenterology and Motility Training during Fellowship
• Constipation in children
• Jonscher R, Belkind-Gerson J. Concise Review: Cellular and Molecular Mechanisms of Postnatal Injury-Induced Enteric Neurogenesis. Stem Cells. 2019 Sep;37(9):1136-1143. PubMed PMID: 31145813
• Zar-Kessler C, Kuo B, Cole E, Benedix A, Belkind-Gerson J. Benefit of Pelvic Floor Physical Therapy in Pediatric Patients with Dyssynergic Defecation Constipation. Dig Dis. 2019;37(6):478-485. PubMed PMID: 31096249
• Zar-Kessler C, Kuo B, Belkind-Gerson J. Botulinum toxin injection for childhood constipation is safe and can be effective regardless of anal sphincter dynamics. J Pediatr Surg. 2018 Apr;53(4):693-697. PubMed PMID: 29395154
• Graham K, Belkind-Gerson J, Darbari A, Boyle JT. Barriers in Neurogastroenterology and Motility Training Experience for Pediatric Gastroenterology Fellows. J Pediatr Gastroenterol Nutr. 2019 Jun;68(6):806-810. PubMed PMID: 30664565
• Probable neuropsychiatric toxicity of polyethylene glycol: roles of media, internet and the caregivers. GastroHep. Volume1, Issue3, May 2019, Pages 118-123
• Letter: probable neuropsychiatric toxicity of polyethylene glycol: roles of media, internet and the caregivers—author reply
• Proceedings of the 2018 Advances in Motility and in Neurogastroenterology: AIMING for the Future, Single Topic Symposium".
• Standards for Training Subspecialists in Pediatric Neurogastroenterology and Motility.
• Schwann cell progenitors give rise to Neurons in the Human Intestine
• Implementation of a Timed Barium Esophagram Protocol for Assessment of Esophageal Function in Children.
• Belkind-Gerson J, Graham HK, Reynolds J, Hotta R, Nagy N, Cheng L, Kamionek M, Shi HN, Aherne CM, Goldstein AM. Colitis promotes neuronal differentiation of Sox2 and PLP1 enteric cells. Sci Rep. 2017 May 31;7(1):2525. PubMed PMID: 28566702
• Cheng LS, Hotta R, Graham HK, Belkind-Gerson J, Nagy N, Goldstein AM. Postnatal human enteric neuronal progenitors can migrate, differentiate, and proliferate in embryonic and postnatal aganglionic gut environments. Pediatr Res. 2017 May;81(5):838-846. PubMed PMID: 28060794
• Peña A, De La Torre L, Belkind-Gerson J, Lovell M, Ketzer J, Bealer J, Bischoff A. Enema-Induced spastic left colon syndrome: An unintended consequence of chronic enema use. J Pediatr Surg. 2020 Oct 31. [Epub ahead of print] PubMed PMID: 33199058
• Khlevner J, Rosen R, Ambartsumyan L, Lusman S, Rosen J, Yacob D, Mousa H, Nurko S, DiLorenzo C, Boruta M, Ratcliffe EM, Feinstein L, Snyder J, Wood RJ, Graham K, Saps M, Gyawali CP, Rodriguez L, Belkind-Gerson J. Development of EPA and Standards in Training in Pediatric Neurogastroenterology and Motility: NASPGHAN and ANMS Position Paper. J Pediatr Gastroenterol Nutr. 2020 Oct 16. [Epub ahead of print] PubMed PMID: 33075010
• Rosenwald KD, Hayes K, Menard-Katcher C, Belkind-Gerson J. Implementation of a Timed Barium Esophagram Protocol for Assessment of Esophageal Function in Children. J Pediatr Gastroenterol Nutr. 2020 Oct;71(4):470-475. PubMed PMID: 32639450
• Ambartsumyan L, Khlevner J, Nurko S, Rosen R, Kaul A, Pandolfino JE, Ratcliffe E, Yacob D, Li BUK, Punati J, Sood M, Rao SSC, Levitt MA, Cocjin JT, Rodriguez L, Flores A, Rosen JM, Belkind-Gerson J, Saps M, Garza JM, Fortunato JE, Schroedl RL, Keefer LA, Friedlander J, Heuckeroth RO, Rao M, El-Chammas K, Vaz K, Chumpitazi BP, Sanghavi R, Matta SKR, Danialifar T, Di Lorenzo C, Darbari A. Proceedings of the 2018 Advances In Motility and In NeuroGastroenterology: AIMING for the Future Single Topic Symposium. J Pediatr Gastroenterol Nutr. 2020 Aug;71(2):e59-e67. PubMed PMID: 32287151
• Jonscher R, Belkind-Gerson J. Concise Review: Cellular and Molecular Mechanisms of Postnatal Injury-Induced Enteric Neurogenesis. Stem Cells. 2019 Sep;37(9):1136-1143. PubMed PMID: 31145813
• Zar-Kessler C, Kuo B, Cole E, Benedix A, Belkind-Gerson J. Benefit of Pelvic Floor Physical Therapy in Pediatric Patients with Dyssynergic Defecation Constipation. Dig Dis. 2019;37(6):478-485. PubMed PMID: 31096249
• Graham K, Belkind-Gerson J, Darbari A, Boyle JT. Barriers in Neurogastroenterology and Motility Training Experience for Pediatric Gastroenterology Fellows. J Pediatr Gastroenterol Nutr. 2019 Jun;68(6):806-810. PubMed PMID: 30664565
• Woods C, Kapur RP, Bischoff A, Lovell M, Arnold M, Peña A, Flockton A, Sharkey KA, Belkind-Gerson J. Neurons populating the rectal extrinsic nerves in humans express neuronal and Schwann cell markers. Neurogastroenterol Motil. 2021 Jul;33(7):e14074. PubMed PMID: 33382200
• Montminy T, Belkind-Gerson J, Kilgore A, Tran P, Mark JA. Evaluating the Accuracy of Anal Botulinum Toxin Injection in Children With Constipation Using Endoscopic Ultrasound. J Pediatr Gastroenterol Nutr. 2022 Apr 1;74(4):e98. PubMed PMID: 35129156
• Vicentini FA, Keenan CM, Wallace LE, Woods C, Cavin JB, Flockton AR, Macklin WB, Belkind-Gerson J, Hirota SA, Sharkey KA. Intestinal microbiota shapes gut physiology and regulates enteric neurons and glia. Microbiome. 2021 Oct 26;9(1):210. PubMed PMID: 34702353
• Peña A, De La Torre L, Belkind-Gerson J, Lovell M, Ketzer J, Bealer J, Bischoff A. Enema-Induced spastic left colon syndrome: An unintended consequence of chronic enema use. J Pediatr Surg. 2021 Feb;56(2):424-428. PubMed PMID: 33199058
• Woods C, Kapur RP, Bischoff A, Lovell M, Arnold M, Peña A, Flockton A, Sharkey KA, Belkind-Gerson J. Neurons populating the rectal extrinsic nerves in humans express neuronal and Schwann cell markers. Neurogastroenterol Motil. 2021 Jul;33(7):e14074. PubMed PMID: 33382200
• Peña A, De La Torre L, Belkind-Gerson J, Lovell M, Ketzer J, Bealer J, Bischoff A. Enema-Induced spastic left colon syndrome: An unintended consequence of chronic enema use. J Pediatr Surg. 2021 Feb;56(2):424-428. PubMed PMID: 33199058
• Khlevner J, Rosen R, Ambartsumyan L, Lusman SS, Rosen JM, Yacob D, Mousa H, Nurko S, Di Lorenzo C, Boruta M, Ratcliffe EM, Feinstein L, Snyder J, Wood RJ, Graham K, Saps M, Gyawali CP, Rodriguez L, Belkind-Gerson J. Development of Entrustable Professional Activities and Standards in Training in Pediatric Neurogastroenterology and Motility: North American Society for Pediatric Gastroenterology, Hepatology and Nutrition and American Neurogastroenterology and Motility Society Position Paper. J Pediatr Gastroenterol Nutr. 2021 Jan 1;72(1):168-180. PubMed PMID: 33075010
• Khlevner J, Rosen R, Ambartsumyan L, Lusman SS, Rosen JM, Yacob D, Mousa H, Nurko S, Di Lorenzo C, Boruta M, Ratcliffe EM, Feinstein L, Snyder J, Wood RJ, Graham K, Saps M, Gyawali CP, Rodriguez L, Belkind-Gerson J. Development of Entrustable Professional Activities and Standards in Training in Pediatric Neurogastroenterology and Motility: North American Society for Pediatric Gastroenterology, Hepatology and Nutrition and American Neurogastroenterology and Motility Society Position Paper. J Pediatr Gastroenterol Nutr. 2021 Jan 1;72(1):168-180. PubMed PMID: 33075010
• Rosenwald KD, Hayes K, Menard-Katcher C, Belkind-Gerson J. Implementation of a Timed Barium Esophagram Protocol for Assessment of Esophageal Function in Children. J Pediatr Gastroenterol Nutr. 2020 Oct;71(4):470-475. PubMed PMID: 32639450
• Ambartsumyan L, Khlevner J, Nurko S, Rosen R, Kaul A, Pandolfino JE, Ratcliffe E, Yacob D, Li BUK, Punati J, Sood M, Rao SSC, Levitt MA, Cocjin JT, Rodriguez L, Flores A, Rosen JM, Belkind-Gerson J, Saps M, Garza JM, Fortunato JE, Schroedl RL, Keefer LA, Friedlander J, Heuckeroth RO, Rao M, El-Chammas K, Vaz K, Chumpitazi BP, Sanghavi R, Matta SKR, Danialifar T, Di Lorenzo C, Darbari A. Proceedings of the 2018 Advances In Motility and In NeuroGastroenterology: AIMING for the Future Single Topic Symposium. J Pediatr Gastroenterol Nutr. 2020 Aug;71(2):e59-e67. PubMed PMID: 32287151
• Crystal Woods, Amanda R. Flockton, Wendy B. Macklin, Keith A. Sharkey, Jaime Belkind- Gerson. Proteolipid protein 1 is involved in the regulation of intestinal motility and barrier function in the mouse. Am J Physiol Gastrointest Liver Physiol. 2023 Feb 1;324(2):G115- G130.
• Alexandra Kilgore and Jaime Belkind-Gerson; The Bidirectional Brain-Gut-Microbiome Axis in Pediatrics: What do we know and how may this change our current treatments? J Pediatr Gastroenterol Nutr. J Pediatr Gastroenterol Nutr 2023 Aug 1;77(2):147-149
• Nicole Maier, Shannon L. Grahek, Jane Halpern, Suzanne Restrepo, Felipe Troncoso, Janet Shimko, Olga Torres, Jaime Belkind-Gerson, David A. Sack, Ann-Mari Svennerholm, Björn Gustafsson, Björn Sjöstrand, Nils Carlin, A. Louis Bourgeois and Chad K. Porter. Efficacy of an Enterotoxigenic Escherichia coli (ETEC) Vaccine on the Incidence and Severity of Traveler’s Diarrhea (TD): Evaluation of Alternative Endpoints and a TD Severity Score. Microorganisms 2023, 11(10), 2414
• Joel Friedlander, Clinton Smith, Nathalie Nguyen, Jeremy Prager, Emily DeBoer, Robin Deterding and Jaime Belkind-Gerson. Functional endoscopic esophageal evaluation of swallowing (fees) using un-sedated trans-nasal endoscopy (TNE). J Pediatr Gastroenterol (in press).
• Crystal Woods, Amanda R. Flockton, and Jaime Belkind-Gerson. Phosphatase and tensin homolog inhibition stimulates gliogenesis in the postnatal enteric nervous system. Submitted to Biomolecules (index 6.5).

Practice Locations

Children's Hospital Colorado Anschutz Medical Campus
13123 East 16th Ave
Aurora, CO 80045
720-777-1234

Hospital Affiliation

• Children's Hospital Colorado

Specialty Information

Specialties

• Pediatric Gastroenterology