Behavioral Neurology and Neuropsychiatry Assistant Professor
My research interest is in better understanding changes to brain function among patients with cognitive problems, including dementia and Alzheimer's disease. I lead a research program within the University of Colorado Alzheimer's and Cognition Center with a goal to develop methods that can detect brain changes very early in Alzheimer's disease, prior to the development of cognitive or memory symptoms. I also work with members of our research team to develop and test new treatments for neurodegenerative diseases, including Alzheimer's disease.
Holden SK, Pelak VS, Sooy T, Heffernan KS, McConnell BV, Pressman PS, Bettcher BM. Development of the Colorado posterior cortical questionnaire within an Alzheimer's disease study cohort. J Clin Exp Neuropsychol. 2022 Apr;44(3):226-236. PubMed PMID: 35913095
McConnell BV, Kronberg E, Medenblik LM, Kheyfets VO, Ramos AR, Sillau SH, Pulver RL, Bettcher BM. The Rise and Fall of Slow Wave Tides: Vacillations in Coupled Slow Wave/Spindle Pairing Shift the Composition of Slow Wave Activity in Accordance With Depth of Sleep. Front Neurosci. 2022;16:915934. PubMed PMID: 35812239
Bettcher BM, Olson KE, Carlson NE, McConnell BV, Boyd T, Adame V, Solano DA, Anton P, Markham N, Thaker AA, Jensen AM, Dallmann EN, Potter H, Coughlan C. Astrogliosis and episodic memory in late life: higher GFAP is related to worse memory and white matter microstructure in healthy aging and Alzheimer's disease. Neurobiol Aging. 2021 Jul;103:68-77. PubMed PMID: 33845398
McConnell BV, Kronberg E, Teale PD, Sillau SH, Fishback GM, Kaplan RI, Fought AJ, Dhanasekaran AR, Berman BD, Ramos AR, McClure RL, Bettcher BM. The Aging Slow Wave: A Shifting Amalgam of Distinct Slow Wave and Spindle Coupling Subtypes Define Slow Wave Sleep Across the Human Lifespan. Sleep. 2021 May 17. [Epub ahead of print] PubMed PMID: 33999194
McConnell, Brice V., et al. "The Aging Slow Wave: A Shifting Amalgam of Distinct Slow Wave and Spindle Coupling Subtypes Define Slow Wave Sleep Across the Human Lifespan." bioRxiv (2020).
McConnell BV, Kaplan RI, Teale PD, Kronberg E, Broussard JL, Guzetti JR, Sillau SH, Dhanasekaran AR, Kluger BM, Berman BD. Feasibility of home-based automated transcranial electrical stimulation during slow wave sleep. Brain Stimul. 2019 May - Jun;12(3):813-815. PubMed PMID: 30819658