William Cornwell, MD
Associate Professor, Medicine-Cardiology

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Medical School:
  • MD, Wright State University Boonshoft School of Medicine (2008)
Graduate School :
  • MSCS, University of Colorado Denver (2020)
Undergraduate School:
  • BS, Ohio State University (OH) (2004)
Residency:
  • University of Michigan Hospitals and Health Centers Program, Internal Medicine (2011)
Fellowships:
  • University of Texas Southwestern Medical School Program, Cardiovascular Disease (2015)
  • University of Texas Southwestern Medical School Program, Advanced Heart Failure and Transplant Cardiology (2016)
Department: Medicine-Cardiology

Professional Titles

  • Advanced Heart Failure, LVAD and Transplant Cardiology
  • Sports Cardiology

Recognition & Awards

  • Emerging Investigator, Circulation: Heart Failure (2021)
    https://www.ahajournals.org/circheartfailure/emerging-investigators
  • Outstanding Early Career Scholarship Program, Department of Medicine (2021)
  • Jo Ann McWhorter Award, UT Southwestern (2016)
    "Fellow of the Year"
  • Alpha Omega Alpha, UT Southwestern (2016)
  • Gold Humanism Honor Society for Humanism in Medicine, Arnold P. Gold Foundation (2007)

Publications

  • Golbus JR, Lopez-Jimenez F, Barac A, Cornwell WK, Dunn P, Forman DE, Martin SS, Schorr EN, Supervia M. Digital Technologies in Cardiac Rehabilitation: A Scientific Advisory from the American Heart Association. Circulation 2022; in press.
  • Edward JA, Cornwell WK. Cardiopulmonary Exercise Testing in Post-Acute Sequelae of SARS CoV-2. http://www.acc.org 2022; in press.
  • Cornwell WK, Buttrick P. Mechanobiology of Exercise-Induced Cardiac Remodeling in Health and Disease. Cardiac Mechanobiology in Physiology and Disease- Cardiac and Vascular Biology. Sprinter International Publishing 2022, in press.
  • Edward JA, Cerbin LP, Groves DW, Quaife RA, Hunter KS, Levine BD, Cornwell WK 3rd. Right Ventricular Dysfunction During Endurance Exercise as Determined by Pressure-Volume Analysis. JACC Case Rep. 2022 Nov 2;4(21):1435-1438. PubMed PMID: 36388707
  • Rudofker EW, Parker H, Cornwell WK 3rd. An Exercise Prescription as a Novel Management Strategy for Treatment of Long COVID. JACC Case Rep. 2022 Oct 19;4(20):1344-1347. PubMed PMID: 36278147
  • Huang J, McDonnell BJ, Lawley JS, Byrd J, Stöhr EJ, Cornwell WK 3rd. Impact of Mechanical Circulatory Support on Exercise Capacity in Patients With Advanced Heart Failure. Exerc Sport Sci Rev. 2022 Oct 1;50(4):222-229. PubMed PMID: 36095073
  • Rao P, Peritz DC, Systrom D, Lewine K, Cornwell WK 3rd, Hsu JJ. Orthostatic and Exercise Intolerance in Recreational and Competitive Athletes With Long COVID. JACC Case Rep. 2022 Sep 7;4(17):1119-1123. PubMed PMID: 36090156
  • Kanwar MK, Selzman CH, Ton VK, Miera O, Cornwell WK 3rd, Antaki J, Drakos S, Shah P. Clinical myocardial recovery in advanced heart failure with long term left ventricular assist device support. J Heart Lung Transplant. 2022 Oct;41(10):1324-1334. PubMed PMID: 35835680
  • Babcock MC, DuBose LE, Hildreth KL, Stauffer BL, Cornwell WK, Kohrt WM, Moreau KL. Age-associated reductions in cardiovagal baroreflex sensitivity are exaggerated in middle-aged and older men with low testosterone. J Appl Physiol (1985). 2022 Aug 1;133(2):403-415. PubMed PMID: 35771224
  • Amin SB, Hansen AB, Mugele H, Simpson LL, Marume K, Moore JP, Cornwell WK 3rd, Lawley JS. High-intensity exercise and passive hot water immersion cause similar postintervention changes in peripheral and cerebral shear. J Appl Physiol (1985). 2022 Aug 1;133(2):390-402. PubMed PMID: 35708700
  • Edward JA, Cornwell WK 3rd. Impact of Exercise on Cerebrovascular Physiology and Risk of Stroke. Stroke. 2022 Jul;53(7):2404-2410. PubMed PMID: 35506387
  • Gluckman TJ, Bhave NM, Allen LA, Chung EH, Spatz ES, Ammirati E, Baggish AL, Bozkurt B, Cornwell WK 3rd, Harmon KG, Kim JH, Lala A, Levine BD, Martinez MW, Onuma O, Phelan D, Puntmann VO, Rajpal S, Taub PR, Verma AK. 2022 ACC Expert Consensus Decision Pathway on Cardiovascular Sequelae of COVID-19 in Adults: Myocarditis and Other Myocardial Involvement, Post-Acute Sequelae of SARS-CoV-2 Infection, and Return to Play: A Report of the American College of Cardiology Solution Set Oversight Committee. J Am Coll Cardiol. 2022 May 3;79(17):1717-1756. PubMed PMID: 35307156
  • Brener MI, Masoumi A, Ng VG, Tello K, Bastos MB, Cornwell WK 3rd, Hsu S, Tedford RJ, Lurz P, Rommel KP, Kresoja KP, Nagueh SF, Kanwar MK, Kapur NK, Hiremath G, Sarraf M, Van Den Enden AJM, Van Mieghem NM, Heerdt PM, Hahn RT, Kodali SK, Sayer GT, Uriel N, Burkhoff D. Invasive Right Ventricular Pressure-Volume Analysis: Basic Principles, Clinical Applications, and Practical Recommendations. Circ Heart Fail. 2022 Jan;15(1):e009101. PubMed PMID: 34963308
  • Cornwell WK 3rd, Pal JD. What's Old Is New Again. Ann Thorac Surg. 2022 Jul;114(1):167. PubMed PMID: 34450177
  • Edward J, Banchs J, Parker H, Cornwell W. Right ventricular function across the spectrum of health and disease. Heart. 2022 May 31. [Epub ahead of print] PubMed PMID: 35641176
  • McDonnell BJ, Cornwell WK, Stohr EJ. Arterial stiffness, hemodynamics and microvascular complications in conditions characterized by low arterial pulsatility. Textbook of Arterial Stiffness and Pulsatile Hemodynamics in Health and Disease. Elsevier 2022.
  • Cornwell WK. Clinical Application of Cerebrovascular Physiology. Neurovascular Sonography. Springer International Publishing 2022, Springer Inc.
  • Cornwell WK. Cerebrovascular Physiology in the Setting of Temporary and Durable Mechanical Circulatory Support. Neurovascular Sonography. Springer International Publishing 2022.
  • Molina EJ, Shah P, Kiernan MS, Cornwell WK 3rd, Copeland H, Takeda K, Fernandez FG, Badhwar V, Habib RH, Jacobs JP, Koehl D, Kirklin JK, Pagani FD, Cowger JA. The Society of Thoracic Surgeons Intermacs 2020 Annual Report. Ann Thorac Surg. 2021 Jan 16. [Epub ahead of print] PubMed PMID: 33465365
  • Sailer C, Edelmann H, Buchanan C, Giro P, Babcock M, Swanson C, Spotts M, Schulte M, Pratt-Cordova A, Coe G, Beindorff M, Page RL 2nd, Ambardekar AV, Pal JD, Kohrt W, Wolfel E, Lawley JS, Tarumi T, Cornwell WK 3rd. Impairments in Blood Pressure Regulation and Cardiac Baroreceptor Sensitivity Among Patients With Heart Failure Supported With Continuous-Flow Left Ventricular Assist Devices. Circ Heart Fail. 2021 Jan;14(1):e007448. PubMed PMID: 33464953
  • Tran T, Muralidhar A, Hunter K, Buchanan C, Coe G, Hieda M, Tompkins C, Zipse M, Spotts MJ, Laing SG, Fosmark K, Hoffman J, Ambardekar AV, Wolfel EE, Lawley J, Levine B, Kohrt WM, Pal J, Cornwell WK 3rd. Right ventricular function and cardiopulmonary performance among patients with heart failure supported by durable mechanical circulatory support devices. J Heart Lung Transplant. 2021 Feb;40(2):128-137. PubMed PMID: 33281029
  • Amin SB, Hansen AB, Mugele H, Willmer F, Gross F, Reimeir B, Cornwell WK, Simpson LL, Moore JP, Romero SA, Lawley JS. Whole body passive heating versus dynamic lower body exercise: a comparison of peripheral hemodynamic profiles. J Appl Physiol (1985). 2021 Jan 1;130(1):160-171. PubMed PMID: 33090910
  • Cornwell WK, Baggish AL, Bhatta YKD, Brosnan MJ, Dehnert C, Guseh JS, Hammer D, Levine BD, Parati G, Wolfel EE. Clinical Implications for Exercise at Altitude Among Individuals with Cardiovascular Disease. A Scientific Statement from the American Heart Association. Journal of the American Heart Association; 2021 https://doi.org/10.1161/JAHA.121.023225
  • Cornwell WK, Stohr E, McDonnell B, Aaronson K, Hayward C, Pal JD. The Future of Mechanical Circulatory Support. Circulation: Heart Failure 2021; 14(8):e008861. doi: 10.1161/CIRCHEARTFAILURE.121.008861
  • Cornwell WK, Levine BD. Altitude travel following COVID-19 infection. http://www.acc.org. Oct 25, 2021. Accessed 0-28-21. https://www.acc.org/latest-in-cardiology/articles/2021/10/25/13/49/altitude-travel-following-covid-19-infection
  • 29. Cornwell WK, Tran T, Cerbin L, Coe G, Muralidhar A, Hunter K, Altman N, Ambardekar A, Tompkins C, Zipse M, Schulte M, O’Gean K, Ostertag M, Hoffman J, Pal J, Lawley JS, Levine BD, Wolfel E, Kohrt W, Buttrick P. New Insights into Resting and Exertional Right Ventricular Performance in the Healthy Adult Heart Through Real-Time Pressure Volume Analysis. Journal of Physiology 2020; 598 (13): 2575-2587.
  • Sailer C, Edelmann H, Buchanan C, Giro P, Babcock M, Swanson C, Spotts, M, Schulte M, Pratt-Cordova A, Coe G, Beindorff M, Page RL, Ambardekar AV, Pal JD, Kohrt W, Wolfel E, Lawley JS, Tarumi T, Cornwell WK III. Impairments in Blood Pressure Regulation and Cardiac Baroreceptor Sensitivity Among Heart Failure Patients Supported with Continuous-Flow Left Ventricular Assist Devices. Circulation: Heart Failure 2021; Jan;14(1):e007448. doi:10.1161/CIRCHEARTFAILURE.120.007448
  • Tran T, Muralidhar A, Hunter K, Buchanan C, Coe G, Hieda M, Tompkins C, Zipse M, Spotts MJ, Laing SG, Fosmark K, Hoffman J, Ambardekar AV, Wolfel EE, Lawley J, Levine B, Kohrt WM, Pal J, Cornwell WK. Right Ventricular Function and Cardiopulmonary Performance Among Heart Failure Patients Supported by Durable Mechanical Circulatory Support Devices. Journal of Heart Lung Transplantation 2021; 40(2): 128-137
  • Cornwell WK¸ Lovering A. Impact of Altitude on Cardiopulmonary and Right Ventricular Hemodynamics During Exercise. Advances in Pulmonary Hypertension 2021; 19(3): 77-79
  • Hansen A, Lawley J, Rickards C, Howden E, Sarwma S, Cornwell WK, Amin S, Mugele H, Marume K, Possnig C, Whitworth L, Williams M, Levine B. Reducing Intracranial Pressure by Reducing Central Venous Pressure: Assessment of potential countermeasures to spaceflight associated neuro-ocular syndrome. Journal of Applied Physiology 2021; 130(2): 283-289.
  • Molina EJ, Shah P, Kiernan MS, Cornwell WK, Copeland H, Takeda K, Fernandez FG, Badhwar V, Habib RH, Jacobs, JP, Koehl D, Kirklin JK, Pagani FD, Cowger JA. The Society of Thoracic Surgeons Intermacs 2020 Annual Report. Annals of Thoracic Surgery; 2021; 111(3): 778-792
  • MacNamara, JP, Koshti V, Cheng IJ, Dias, KA, Hearon CM, Cornwell WK, Howden EJ, Levine BD, Sarma S. The Role of Systolic-Diastolic Coupling in Distinguishing Impaired Diastolic Recoil in Healthy Aging and Heart Failure with Preserved Ejection Fraction. Echocardiography 2021; 38(2): 261-270.
  • Gopinathannair R, Chen LY, Chung MK, Cornwell WK, Furie KL, Lakkireddy DR, Marrouche NF, Natale A, Olshansky B, Joglar JA. Managing Atrial Fibrillation in Patients with Heart Failure and Reduced Ejection Fraction. A Scientific Statement from the American Heart Association, Circulation: Arrhythmia and Electrophysiology 2021; Jun;14(6).
  • Hansen AB, Lawley JS, Rickards CA, Howden EJ, Sarma S, Cornwell WK 3rd, Amin SB, Mugele H, Marume K, Possnig C, Whitworth LA, Williams MA, Levine BD. Reducing Intracranial Pressure by Reducing Central Venous Pressure: Assessment of potential countermeasures to spaceflight associated neuro-ocular syndrome. J Appl Physiol (1985). 2020 Dec 3. [Epub ahead of print] PubMed PMID: 33270516
  • Pal JD, Cleveland J, Reece BT, Byrd J, Pierce CN, Brieke A, Cornwell WK 3rd. Cardiac Emergencies in Patients with Left Ventricular Assist Devices. Heart Fail Clin. 2020 Jul;16(3):295-303. PubMed PMID: 32503753
  • Cornwell WK, Tran T, Cerbin L, Coe G, Muralidhar A, Hunter K, Altman N, Ambardekar AV, Tompkins C, Zipse M, Schulte M, O'Gean K, Ostertag M, Hoffman J, Pal JD, Lawley JS, Levine BD, Wolfel E, Kohrt WM, Buttrick P. New insights into resting and exertional right ventricular performance in the healthy heart through real-time pressure-volume analysis. J Physiol. 2020 Jul;598(13):2575-2587. PubMed PMID: 32347547
  • Hydren JR, Cornwell WK 3rd, Richardson RS, Drakos SG. Exercise Capacity in Mechanically Supported Advanced Heart Failure Patients: It Is All About the Beat. ASAIO J. 2020 Apr;66(4):339-342. PubMed PMID: 32221141
  • McDonnell BJ, Rosenblum H, Cornwell WK 3rd, Kanwar M, Cockcroft JR, Stöhr EJ. Bionic women and men - Part 2: Arterial stiffness in heart failure patients implanted with left ventricular assist devices. Exp Physiol. 2020 May;105(5):755-758. PubMed PMID: 32144954
  • Buchanan C, Kanwar M, Cockcroft JR, McDonnell B, Stöhr EJ, Cornwell WK 3rd. Bionic women and men - Part 4: Cardiovascular, cerebrovascular and exercise responses among patients supported with left ventricular assist devices. Exp Physiol. 2020 May;105(5):763-766. PubMed PMID: 32105385
  • Stöhr EJ, Cornwell WK 3rd, Kanwar M, Cockcroft JR, McDonnell BJ. Bionic women and men - Part 1: Cardiovascular lessons from heart failure patients implanted with left ventricular assist devices. Exp Physiol. 2020 May;105(5):749-754. PubMed PMID: 32104940
  • Kanwar M, McDonnell BJ, Rosenblum H, Cockcroft JR, Stöhr EJ, Cornwell WK 3rd. Bionic women and men - Part 3: Right ventricular dysfunction in patients implanted with left ventricular assist devices. Exp Physiol. 2020 May;105(5):759-762. PubMed PMID: 32103556
  • Hydren JR, Cornwell WK, Richardson RS, Drakos SG. Exercise Capacity in Mechanically Supported Advanced Herat Failure Patients: It is All About the Beat. ASAIO J 2020; 66(4): 339-342.
  • Lawley JS, Petersen LG, Howden EJ, Sarma S, Cornwell WK, Zhang R, Whitworth LA, Williams MA, Levine BD. Effect of gravity and microgravity on intracranial pressure. J Physiol. 2017 Jan 16. [Epub ahead of print] PubMed PMID: 28092926
  • Gagnon D, Romero SA, Ngo H, Sarma S, Cornwell WK 3rd, Poh PY, Stoller D, Levine BD, Crandall CG. Healthy aging does not compromise the augmentation of cardiac function during heat stress. J Appl Physiol (1985). 2016 Oct 1;121(4):885-892. PubMed PMID: 27609201
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Practice Locations

UCHealth Heart & Vascular Center - Anschutz
12505 E. 16th Ave
Anschutz Inpatient Pavilion 2, 3rd floor
Aurora, CO 80045
720-848-5300

UCHealth Heart Failure Program - Anschutz
12505 E. 16th Ave
Anschutz Inpatient Pavilion 2, 3rd floor
Aurora, CO 80045
720-848-5300

CU Medicine Cardiology - Cherry Creek Medical Center
100 Cook Street
Suite 412
Denver, CO 80206
720-516-9403

Hospital Affiliation
  • University of Colorado Hospital
Center Affiliations

Specialty Information

Specialties
  • Cardiovascular Disease, Board Certification
  • Advanced Heart Failure and Transplant Cardiology, Board Certification
  • Sports Medicine, Board Certification
Conditions & Treatments
  • Heart and Circulation
  • Heart and Circulation - Cardiomyopathy
  • Heart and Circulation - Circulatory Disorders
  • Heart and Circulation - Coronary Disease
  • Heart and Circulation - Heart Attack
  • Heart and Circulation - Heart Failure
  • Heart and Circulation - Structural Heart Disease
  • Surgery - Heart Transplant Surgery
  • Surgery
Clinical Interests
-Heart Failure with Reduced Ejection Fraction -Heart Failure with Preserved Ejection Fraction and cardiomyopathies -Left Ventricular Assist Devices -Post-COVID 19 "Long Hauler Syndrome" -Sports Cardiology -Athletic Heart -Pre-season screenings -Altitude/Environmental Medicine -Hypoxia -Dyspnea of unclear etiology -Syncope -Cardiovascular Disease

Personal Interests
Exercise, skiing, fishing, crossfit, reading

Public Speaking
Yes

General Information

Medical Schools:
  • MD, Wright State University Boonshoft School of Medicine (2008)
Graduate Schools:
  • MSCS, University of Colorado Denver (2020)
Undergraduate Schools:
  • BS, Ohio State University (OH) (2004)
Residency Programs:
  • University of Michigan Hospitals and Health Centers Program, Internal Medicine (2011)
Fellowships:
  • University of Texas Southwestern Medical School Program, Cardiovascular Disease (2015)
  • University of Texas Southwestern Medical School Program, Advanced Heart Failure and Transplant Cardiology (2016)
Department: Medicine-Cardiology
SOM Resources
CU Resources
Contact Us
CU Anschutz
Fitzsimons Building
13001 East 17th Place
Campus Box C290
Aurora, CO 80045

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