William Cornwell, MD

Professional Titles

• Advanced Heart Failure, LVAD and Transplant Cardiology
• Sports Cardiology

Recognitions

• Outstanding Reviewer, Circulation (2024)
• Outstanding Faculty Award for Research and Mentoring, University of Colorado (2023)
• Emerging Investigator, Circulation: Heart Failure (2021)
  https://www.ahajournals.org/circheartfailure/emerging-investigators
• Outstanding Early Career Scholarship Program, Department of Medicine (2021)
• Jo Ann McWhorter Award, UT Southwestern (2016)
  "Fellow of the Year"
• Alpha Omega Alpha, UT Southwestern (2016)
• Gold Humanism Honor Society for Humanism in Medicine, Arnold P. Gold Foundation (2007)

Publications

• Van Ochten N, Rudofker EW, Cornwell WK. Altitude Adversities: Is It Safe for People with Cardiovascular Disease to Travel to Moderate-High Altitude?. High Alt Med Biol. 2025 Mar 6. [Epub ahead of print] PubMed PMID: 40045761
• Cornwell W, Baggish AL, Dehnert C, Levine BD, Luks AM. Clinical Conundrum: Climbing at the Extremes of High Elevation with Nonischemic Cardiomyopathy. High Alt Med Biol. 2025 Jan 9. [Epub ahead of print] PubMed PMID: 39783957
• Rudofker E, Ochten NV, Edward J, Parker H, Wulff K, Suckow E, Forbes L, Cornwell WK 3rd. Exercise Testing in Elite Athletes. Heart Fail Clin. 2025 Jan;21(1):15-25. PubMed PMID: 39550077
• Bushnell C, Kernan WN, Sharrief AZ, Chaturvedi S, Cole JW, Cornwell WK 3rd, Cosby-Gaither C, Doyle S, Goldstein LB, Lennon O, Levine DA, Love M, Miller E, Nguyen-Huynh M, Rasmussen-Winkler J, Rexrode KM, Rosendale N, Sarma S, Shimbo D, Simpkins AN, Spatz ES, Sun LR, Tangpricha V, Turnage D, Velazquez G, Whelton PK. 2024 Guideline for the Primary Prevention of Stroke: A Guideline From the American Heart Association/American Stroke Association. Stroke. 2024 Dec;55(12):e344-e424. PubMed PMID: 39429201
• Rockstrom MD, Jin Y, Peterson RA, Hountras P, Badesch D, Gu S, Park B, Messenger J, Forbes LM, Cornwell WK 3rd, Bull TM. The effects of oxygenation on acute vasodilator challenge in pulmonary arterial hypertension. Pulm Circ. 2024 Apr;14(2):e12375. PubMed PMID: 38736893
• Cornwell WK 3rd, Levine BD. Unraveling the Unsolved Mysteries of the Athletic Heart. Circulation. 2024 Apr 30;149(18):1416-1418. PubMed PMID: 38683901
• Forbes LM, Bull TM, Lahm T, Sisson T, O'Gean K, Lawley JS, Hunter K, Levine BD, Lovering A, Roach RC, Subudhi AW, Cornwell WK 3rd. Right ventricular performance during acute hypoxic exercise. J Physiol. 2024 Nov;602(21):5523-5537. PubMed PMID: 38409819
• Scheel PJ III,, Cubero Salazar IM, Friedman S, Haber L, Mukherjee M, Kauffman M, Weller A, Alkhunaizi F, Gilotra NA, Sharma K, Kilic A, Hassoun PM, Cornwell WK, Tedford RJ, Hsu S. Occult right ventricular dysfunction and right ventricular-vascular uncoupling in left ventricular assist device recipients. J Heart Lung Transplant. 2024 Apr;43(4):594-603. PubMed PMID: 38036276
• Stumph JD, Cornwell WK 3rd, Rosenberg MA, Khodaee M. Profound First-Degree Atrioventricular Block in a High-Level Basketball Athlete. Sports Health. 2024 Nov-Dec;16(6):938-941. PubMed PMID: 37946461
• Buchanan C, Buchanan C, Riordan M, Byrd J, Schulte M, Kohrt WM, Ambardekar AV, Allen LA, Wolfel G, Lawley J, Levine BD, Cornwell WK 3rd. Cardiopulmonary Performance Among Heart Failure Patients Before and After Left Ventricular Assist Device Implantation. JACC Heart Fail. 2024 Jan;12(1):117-129. PubMed PMID: 37632493
• Buchanan C, Buchanan C, Riordan M, Byrd J, Schulte M, Kohrt WM, Ambardekar AV, Allen LA, Wolfel G, Lawley J, Levine BD, Cornwell WK 3rd. Cardiopulmonary Performance Among Heart Failure Patients Before and After Left Ventricular Assist Device Implantation. JACC Heart Fail. 2024 Jan;12(1):117-129. PubMed PMID: 37632493
• Scheel PJ III,, Cubero Salazar IM, Friedman S, Haber L, Mukherjee M, Kauffman M, Weller A, Alkhunaizi F, Gilotra NA, Sharma K, Kilic A, Hassoun PM, Cornwell WK, Tedford RJ, Hsu S. Occult right ventricular dysfunction and right ventricular-vascular uncoupling in left ventricular assist device recipients. J Heart Lung Transplant. 2023 Nov 28. [Epub ahead of print] PubMed PMID: 38036276
• Stumph JD, Cornwell WK 3rd, Rosenberg MA, Khodaee M. Profound First-Degree Atrioventricular Block in a High-Level Basketball Athlete. Sports Health. 2023 Nov 9;:19417381231210297. [Epub ahead of print] PubMed PMID: 37946461
• Edward JA, Peruri A, Rudofker E, Shamapant N, Parker H, Cotter R, Sabin K, Lawley J, Cornwell WK 3rd. Characteristics and Treatment of Exercise Intolerance in Patients With Long COVID. J Cardiopulm Rehabil Prev. 2023 Nov 1;43(6):400-406. PubMed PMID: 37646620
• Edward JA, Parker H, Stöhr EJ, McDonnell BJ, O'Gean K, Schulte M, Lawley JS, Cornwell WK 3rd. Exertional Cardiac and Pulmonary Vascular Hemodynamics in Patients With Heart Failure With Reduced Ejection Fraction. J Card Fail. 2023 Sep;29(9):1276-1284. PubMed PMID: 36871613
• Forbes LM, Bull TM, Lahm T, Make BJ, Cornwell WK 3rd. Exercise Testing in the Risk Assessment of Pulmonary Hypertension. Chest. 2023 Sep;164(3):736-746. PubMed PMID: 37061028
• Forbes LM, Bull TM, Lahm T, Lawley JS, Hunter K, Levine BD, Lovering A, Roach RC, Subudhi AW, Cornwell WK 3rd. Right Ventricular Response to Acute Hypoxia among Healthy Humans. Am J Respir Crit Care Med. 2023 Aug 1;208(3):333-336. PubMed PMID: 37311248
• Golbus JR, Lopez-Jimenez F, Barac A, Cornwell WK 3rd, Dunn P, Forman DE, Martin SS, Schorr EN, Supervia M. Digital Technologies in Cardiac Rehabilitation: A Science Advisory From the American Heart Association. Circulation. 2023 Jul 4;148(1):95-107. PubMed PMID: 37272365
• Edward J, Banchs J, Parker H, Cornwell W. Right ventricular function across the spectrum of health and disease. Heart. 2023 Feb 14;109(5):349-355. PubMed PMID: 35641176
• Golbus JR, Lopez-Jimenez F, Barac A, Cornwell WK, Dunn P, Forman DE, Martin SS, Schorr EN, Supervia M. Digital Technologies in Cardiac Rehabilitation: A Scientific Advisory from the American Heart Association. Circulation 2022; in press.
• Edward JA, Cornwell WK. Cardiopulmonary Exercise Testing in Post-Acute Sequelae of SARS CoV-2. http://www.acc.org 2022; in press.
• Swat SA, Helmkamp LJ, Tietbohl C, Thompson JS, Fitzgerald M, McIlvennan CK, Harger G, Ho PM, Ahmad FS, Ahmad T, Buttrick P, Allen LA. Clinical Inertia Among Outpatients With Heart Failure: Application of Treatment Nonintensification Taxonomy to EPIC-HF Trial. JACC Heart Fail. 2023 Nov;11(11):1579-1591. PubMed PMID: 37589610
• Cornwell WK, Buttrick P. Mechanobiology of Exercise-Induced Cardiac Remodeling in Health and Disease. Cardiac Mechanobiology in Physiology and Disease- Cardiac and Vascular Biology. Sprinter International Publishing 2022, in press.
• Cornwell WK. Clinical Application of Cerebrovascular Physiology. Neurovascular Sonography. Springer International Publishing 2022, Springer Inc.
• Cornwell WK. Cerebrovascular Physiology in the Setting of Temporary and Durable Mechanical Circulatory Support. Neurovascular Sonography. Springer International Publishing 2022.
• Edward JA, Cerbin LP, Groves DW, Quaife RA, Hunter KS, Levine BD, Cornwell WK 3rd. Right Ventricular Dysfunction During Endurance Exercise as Determined by Pressure-Volume Analysis. JACC Case Rep. 2022 Nov 2;4(21):1435-1438. PubMed PMID: 36388707
• Rudofker EW, Parker H, Cornwell WK 3rd. An Exercise Prescription as a Novel Management Strategy for Treatment of Long COVID. JACC Case Rep. 2022 Oct 19;4(20):1344-1347. PubMed PMID: 36278147
• Huang J, McDonnell BJ, Lawley JS, Byrd J, Stöhr EJ, Cornwell WK 3rd. Impact of Mechanical Circulatory Support on Exercise Capacity in Patients With Advanced Heart Failure. Exerc Sport Sci Rev. 2022 Oct 1;50(4):222-229. PubMed PMID: 36095073
• Rao P, Peritz DC, Systrom D, Lewine K, Cornwell WK 3rd, Hsu JJ. Orthostatic and Exercise Intolerance in Recreational and Competitive Athletes With Long COVID. JACC Case Rep. 2022 Sep 7;4(17):1119-1123. PubMed PMID: 36090156
• Kanwar MK, Selzman CH, Ton VK, Miera O, Cornwell WK 3rd, Antaki J, Drakos S, Shah P. Clinical myocardial recovery in advanced heart failure with long term left ventricular assist device support. J Heart Lung Transplant. 2022 Oct;41(10):1324-1334. PubMed PMID: 35835680
• Babcock MC, DuBose LE, Hildreth KL, Stauffer BL, Cornwell WK, Kohrt WM, Moreau KL. Age-associated reductions in cardiovagal baroreflex sensitivity are exaggerated in middle-aged and older men with low testosterone. J Appl Physiol (1985). 2022 Aug 1;133(2):403-415. PubMed PMID: 35771224
• Amin SB, Hansen AB, Mugele H, Simpson LL, Marume K, Moore JP, Cornwell WK 3rd, Lawley JS. High-intensity exercise and passive hot water immersion cause similar postintervention changes in peripheral and cerebral shear. J Appl Physiol (1985). 2022 Aug 1;133(2):390-402. PubMed PMID: 35708700
• Edward JA, Cornwell WK 3rd. Impact of Exercise on Cerebrovascular Physiology and Risk of Stroke. Stroke. 2022 Jul;53(7):2404-2410. PubMed PMID: 35506387
• Gluckman TJ, Bhave NM, Allen LA, Chung EH, Spatz ES, Ammirati E, Baggish AL, Bozkurt B, Cornwell WK 3rd, Harmon KG, Kim JH, Lala A, Levine BD, Martinez MW, Onuma O, Phelan D, Puntmann VO, Rajpal S, Taub PR, Verma AK. 2022 ACC Expert Consensus Decision Pathway on Cardiovascular Sequelae of COVID-19 in Adults: Myocarditis and Other Myocardial Involvement, Post-Acute Sequelae of SARS-CoV-2 Infection, and Return to Play: A Report of the American College of Cardiology Solution Set Oversight Committee. J Am Coll Cardiol. 2022 May 3;79(17):1717-1756. PubMed PMID: 35307156
• Brener MI, Masoumi A, Ng VG, Tello K, Bastos MB, Cornwell WK 3rd, Hsu S, Tedford RJ, Lurz P, Rommel KP, Kresoja KP, Nagueh SF, Kanwar MK, Kapur NK, Hiremath G, Sarraf M, Van Den Enden AJM, Van Mieghem NM, Heerdt PM, Hahn RT, Kodali SK, Sayer GT, Uriel N, Burkhoff D. Invasive Right Ventricular Pressure-Volume Analysis: Basic Principles, Clinical Applications, and Practical Recommendations. Circ Heart Fail. 2022 Jan;15(1):e009101. PubMed PMID: 34963308
• Cornwell WK 3rd, Pal JD. What's Old Is New Again. Ann Thorac Surg. 2022 Jul;114(1):167. PubMed PMID: 34450177
• Edward J, Banchs J, Parker H, Cornwell W. Right ventricular function across the spectrum of health and disease. Heart. 2022 May 31. [Epub ahead of print] PubMed PMID: 35641176
• McDonnell BJ, Cornwell WK, Stohr EJ. Arterial stiffness, hemodynamics and microvascular complications in conditions characterized by low arterial pulsatility. Textbook of Arterial Stiffness and Pulsatile Hemodynamics in Health and Disease. Elsevier 2022.
• Edward JA, Cerbin LP, Groves DW, Quaife RA, Hunter KS, Levine BD, Cornwell WK 3rd. Right Ventricular Dysfunction During Endurance Exercise as Determined by Pressure-Volume Analysis. JACC Case Rep. 2022 Nov 2;4(21):1435-1438. PubMed PMID: 36388707
• Rudofker EW, Parker H, Cornwell WK 3rd. An Exercise Prescription as a Novel Management Strategy for Treatment of Long COVID. JACC Case Rep. 2022 Oct 19;4(20):1344-1347. PubMed PMID: 36278147
• Huang J, McDonnell BJ, Lawley JS, Byrd J, Stöhr EJ, Cornwell WK 3rd. Impact of Mechanical Circulatory Support on Exercise Capacity in Patients With Advanced Heart Failure. Exerc Sport Sci Rev. 2022 Oct 1;50(4):222-229. PubMed PMID: 36095073
• Kanwar MK, Selzman CH, Ton VK, Miera O, Cornwell WK 3rd, Antaki J, Drakos S, Shah P. Clinical myocardial recovery in advanced heart failure with long term left ventricular assist device support. J Heart Lung Transplant. 2022 Oct;41(10):1324-1334. PubMed PMID: 35835680
• Rao P, Peritz DC, Systrom D, Lewine K, Cornwell WK 3rd, Hsu JJ. Orthostatic and Exercise Intolerance in Recreational and Competitive Athletes With Long COVID. JACC Case Rep. 2022 Sep 7;4(17):1119-1123. PubMed PMID: 36090156
• Babcock MC, DuBose LE, Hildreth KL, Stauffer BL, Cornwell WK, Kohrt WM, Moreau KL. Age-associated reductions in cardiovagal baroreflex sensitivity are exaggerated in middle-aged and older men with low testosterone. J Appl Physiol (1985). 2022 Aug 1;133(2):403-415. PubMed PMID: 35771224
• Cornwell WK 3rd, Pal JD. What's Old Is New Again. Ann Thorac Surg. 2022 Jul;114(1):167. PubMed PMID: 34450177
• Edward JA, Cornwell WK 3rd. Impact of Exercise on Cerebrovascular Physiology and Risk of Stroke. Stroke. 2022 Jul;53(7):2404-2410. PubMed PMID: 35506387
• Gluckman TJ, Bhave NM, Allen LA, Chung EH, Spatz ES, Ammirati E, Baggish AL, Bozkurt B, Cornwell WK 3rd, Harmon KG, Kim JH, Lala A, Levine BD, Martinez MW, Onuma O, Phelan D, Puntmann VO, Rajpal S, Taub PR, Verma AK. 2022 ACC Expert Consensus Decision Pathway on Cardiovascular Sequelae of COVID-19 in Adults: Myocarditis and Other Myocardial Involvement, Post-Acute Sequelae of SARS-CoV-2 Infection, and Return to Play: A Report of the American College of Cardiology Solution Set Oversight Committee. J Am Coll Cardiol. 2022 May 3;79(17):1717-1756. PubMed PMID: 35307156
• Brener MI, Masoumi A, Ng VG, Tello K, Bastos MB, Cornwell WK 3rd, Hsu S, Tedford RJ, Lurz P, Rommel KP, Kresoja KP, Nagueh SF, Kanwar MK, Kapur NK, Hiremath G, Sarraf M, Van Den Enden AJM, Van Mieghem NM, Heerdt PM, Hahn RT, Kodali SK, Sayer GT, Uriel N, Burkhoff D. Invasive Right Ventricular Pressure-Volume Analysis: Basic Principles, Clinical Applications, and Practical Recommendations. Circ Heart Fail. 2022 Jan;15(1):e009101. PubMed PMID: 34963308
• Cornwell WK 3rd, Baggish AL, Bhatta YKD, Brosnan MJ, Dehnert C, Guseh JS, Hammer D, Levine BD, Parati G, Wolfel EE. Clinical Implications for Exercise at Altitude Among Individuals With Cardiovascular Disease: A Scientific Statement From the American Heart Association. J Am Heart Assoc. 2021 Oct 5;10(19):e023225. PubMed PMID: 34496612
• Cornwell WK 3rd, Stöhr EJ, McDonnell BJ, Aaronson K, Hayward C, Pal JD. The Future of Mechanical Circulatory Support. Circ Heart Fail. 2021 Aug;14(8):e008861. PubMed PMID: 34340525
• Gopinathannair R, Chen LY, Chung MK, Cornwell WK, Furie KL, Lakkireddy DR, Marrouche NF, Natale A, Olshansky B, Joglar JA. Managing Atrial Fibrillation in Patients With Heart Failure and Reduced Ejection Fraction: A Scientific Statement From the American Heart Association. Circ Arrhythm Electrophysiol. 2021 Jun;14(6):HAE0000000000000078. PubMed PMID: 34129347
• Molina EJ, Shah P, Kiernan MS, Cornwell WK 3rd, Copeland H, Takeda K, Fernandez FG, Badhwar V, Habib RH, Jacobs JP, Koehl D, Kirklin JK, Pagani FD, Cowger JA. The Society of Thoracic Surgeons Intermacs 2020 Annual Report. Ann Thorac Surg. 2021 Mar;111(3):778-792. PubMed PMID: 33465365
• Hansen AB, Lawley JS, Rickards CA, Howden EJ, Sarma S, Cornwell WK 3rd, Amin SB, Mugele H, Marume K, Possnig C, Whitworth LA, Williams MA, Levine BD. Reducing intracranial pressure by reducing central venous pressure: assessment of potential countermeasures to spaceflight-associated neuro-ocular syndrome. J Appl Physiol (1985). 2021 Feb 1;130(2):283-289. PubMed PMID: 33270516
• Tran T, Muralidhar A, Hunter K, Buchanan C, Coe G, Hieda M, Tompkins C, Zipse M, Spotts MJ, Laing SG, Fosmark K, Hoffman J, Ambardekar AV, Wolfel EE, Lawley J, Levine B, Kohrt WM, Pal J, Cornwell WK 3rd. Right ventricular function and cardiopulmonary performance among patients with heart failure supported by durable mechanical circulatory support devices. J Heart Lung Transplant. 2021 Feb;40(2):128-137. PubMed PMID: 33281029
• MacNamara JP, Koshti V, Cheng IJ, Dias KA, Hearon CM, Cornwell W 3rd, Howden EJ, Levine BD, Sarma S. The role of systolic-diastolic coupling in distinguishing impaired diastolic recoil in healthy aging and heart failure with preserved ejection fraction. Echocardiography. 2021 Feb;38(2):261-270. PubMed PMID: 33438312
• Sailer C, Edelmann H, Buchanan C, Giro P, Babcock M, Swanson C, Spotts M, Schulte M, Pratt-Cordova A, Coe G, Beindorff M, Page RL 2nd, Ambardekar AV, Pal JD, Kohrt W, Wolfel E, Lawley JS, Tarumi T, Cornwell WK 3rd. Impairments in Blood Pressure Regulation and Cardiac Baroreceptor Sensitivity Among Patients With Heart Failure Supported With Continuous-Flow Left Ventricular Assist Devices. Circ Heart Fail. 2021 Jan;14(1):e007448. PubMed PMID: 33464953
• Amin SB, Hansen AB, Mugele H, Willmer F, Gross F, Reimeir B, Cornwell WK, Simpson LL, Moore JP, Romero SA, Lawley JS. Whole body passive heating versus dynamic lower body exercise: a comparison of peripheral hemodynamic profiles. J Appl Physiol (1985). 2021 Jan 1;130(1):160-171. PubMed PMID: 33090910
• Amin SB, Hansen AB, Mugele H, Willmer F, Gross F, Reimeir B, Cornwell WK, Simpson LL, Moore JP, Romero SA, Lawley JS. Whole body passive heating versus dynamic lower body exercise: a comparison of peripheral hemodynamic profiles. J Appl Physiol (1985). 2021 Jan 1;130(1):160-171. PubMed PMID: 33090910
• Molina EJ, Shah P, Kiernan MS, Cornwell WK 3rd, Copeland H, Takeda K, Fernandez FG, Badhwar V, Habib RH, Jacobs JP, Koehl D, Kirklin JK, Pagani FD, Cowger JA. The Society of Thoracic Surgeons Intermacs 2020 Annual Report. Ann Thorac Surg. 2021 Jan 16. [Epub ahead of print] PubMed PMID: 33465365
• Sailer C, Edelmann H, Buchanan C, Giro P, Babcock M, Swanson C, Spotts M, Schulte M, Pratt-Cordova A, Coe G, Beindorff M, Page RL 2nd, Ambardekar AV, Pal JD, Kohrt W, Wolfel E, Lawley JS, Tarumi T, Cornwell WK 3rd. Impairments in Blood Pressure Regulation and Cardiac Baroreceptor Sensitivity Among Patients With Heart Failure Supported With Continuous-Flow Left Ventricular Assist Devices. Circ Heart Fail. 2021 Jan;14(1):e007448. PubMed PMID: 33464953
• Tran T, Muralidhar A, Hunter K, Buchanan C, Coe G, Hieda M, Tompkins C, Zipse M, Spotts MJ, Laing SG, Fosmark K, Hoffman J, Ambardekar AV, Wolfel EE, Lawley J, Levine B, Kohrt WM, Pal J, Cornwell WK 3rd. Right ventricular function and cardiopulmonary performance among patients with heart failure supported by durable mechanical circulatory support devices. J Heart Lung Transplant. 2021 Feb;40(2):128-137. PubMed PMID: 33281029
• Sailer C, Edelmann H, Buchanan C, Giro P, Babcock M, Swanson C, Spotts, M, Schulte M, Pratt-Cordova A, Coe G, Beindorff M, Page RL, Ambardekar AV, Pal JD, Kohrt W, Wolfel E, Lawley JS, Tarumi T, Cornwell WK III. Impairments in Blood Pressure Regulation and Cardiac Baroreceptor Sensitivity Among Heart Failure Patients Supported with Continuous-Flow Left Ventricular Assist Devices. Circulation: Heart Failure 2021; Jan;14(1):e007448. doi:10.1161/CIRCHEARTFAILURE.120.007448
• Tran T, Muralidhar A, Hunter K, Buchanan C, Coe G, Hieda M, Tompkins C, Zipse M, Spotts MJ, Laing SG, Fosmark K, Hoffman J, Ambardekar AV, Wolfel EE, Lawley J, Levine B, Kohrt WM, Pal J, Cornwell WK. Right Ventricular Function and Cardiopulmonary Performance Among Heart Failure Patients Supported by Durable Mechanical Circulatory Support Devices. Journal of Heart Lung Transplantation 2021; 40(2): 128-137
• Cornwell WK¸ Lovering A. Impact of Altitude on Cardiopulmonary and Right Ventricular Hemodynamics During Exercise. Advances in Pulmonary Hypertension 2021; 19(3): 77-79
• Hansen A, Lawley J, Rickards C, Howden E, Sarwma S, Cornwell WK, Amin S, Mugele H, Marume K, Possnig C, Whitworth L, Williams M, Levine B. Reducing Intracranial Pressure by Reducing Central Venous Pressure: Assessment of potential countermeasures to spaceflight associated neuro-ocular syndrome. Journal of Applied Physiology 2021; 130(2): 283-289.
• Molina EJ, Shah P, Kiernan MS, Cornwell WK, Copeland H, Takeda K, Fernandez FG, Badhwar V, Habib RH, Jacobs, JP, Koehl D, Kirklin JK, Pagani FD, Cowger JA. The Society of Thoracic Surgeons Intermacs 2020 Annual Report. Annals of Thoracic Surgery; 2021; 111(3): 778-792
• MacNamara, JP, Koshti V, Cheng IJ, Dias, KA, Hearon CM, Cornwell WK, Howden EJ, Levine BD, Sarma S. The Role of Systolic-Diastolic Coupling in Distinguishing Impaired Diastolic Recoil in Healthy Aging and Heart Failure with Preserved Ejection Fraction. Echocardiography 2021; 38(2): 261-270.
• Gopinathannair R, Chen LY, Chung MK, Cornwell WK, Furie KL, Lakkireddy DR, Marrouche NF, Natale A, Olshansky B, Joglar JA. Managing Atrial Fibrillation in Patients with Heart Failure and Reduced Ejection Fraction. A Scientific Statement from the American Heart Association, Circulation: Arrhythmia and Electrophysiology 2021; Jun;14(6).
• Cornwell WK, Levine BD. Altitude travel following COVID-19 infection. http://www.acc.org. Oct 25, 2021. Accessed 0-28-21. https://www.acc.org/latest-in-cardiology/articles/2021/10/25/13/49/altitude-travel-following-covid-19-infection
• 29. Cornwell WK, Tran T, Cerbin L, Coe G, Muralidhar A, Hunter K, Altman N, Ambardekar A, Tompkins C, Zipse M, Schulte M, O’Gean K, Ostertag M, Hoffman J, Pal J, Lawley JS, Levine BD, Wolfel E, Kohrt W, Buttrick P. New Insights into Resting and Exertional Right Ventricular Performance in the Healthy Adult Heart Through Real-Time Pressure Volume Analysis. Journal of Physiology 2020; 598 (13): 2575-2587.
• Cornwell WK, Baggish AL, Bhatta YKD, Brosnan MJ, Dehnert C, Guseh JS, Hammer D, Levine BD, Parati G, Wolfel EE. Clinical Implications for Exercise at Altitude Among Individuals with Cardiovascular Disease. A Scientific Statement from the American Heart Association. Journal of the American Heart Association; 2021 https://doi.org/10.1161/JAHA.121.023225
• Cornwell WK, Stohr E, McDonnell B, Aaronson K, Hayward C, Pal JD. The Future of Mechanical Circulatory Support. Circulation: Heart Failure 2021; 14(8):e008861. doi: 10.1161/CIRCHEARTFAILURE.121.008861
• Hydren JR, Cornwell WK, Richardson RS, Drakos SG. Exercise Capacity in Mechanically Supported Advanced Herat Failure Patients: It is All About the Beat. ASAIO J 2020; 66(4): 339-342.
• Hansen AB, Lawley JS, Rickards CA, Howden EJ, Sarma S, Cornwell WK 3rd, Amin SB, Mugele H, Marume K, Possnig C, Whitworth LA, Williams MA, Levine BD. Reducing Intracranial Pressure by Reducing Central Venous Pressure: Assessment of potential countermeasures to spaceflight associated neuro-ocular syndrome. J Appl Physiol (1985). 2020 Dec 3. [Epub ahead of print] PubMed PMID: 33270516
• Pal JD, Cleveland J, Reece BT, Byrd J, Pierce CN, Brieke A, Cornwell WK 3rd. Cardiac Emergencies in Patients with Left Ventricular Assist Devices. Heart Fail Clin. 2020 Jul;16(3):295-303. PubMed PMID: 32503753
• Cornwell WK, Tran T, Cerbin L, Coe G, Muralidhar A, Hunter K, Altman N, Ambardekar AV, Tompkins C, Zipse M, Schulte M, O'Gean K, Ostertag M, Hoffman J, Pal JD, Lawley JS, Levine BD, Wolfel E, Kohrt WM, Buttrick P. New insights into resting and exertional right ventricular performance in the healthy heart through real-time pressure-volume analysis. J Physiol. 2020 Jul;598(13):2575-2587. PubMed PMID: 32347547
• Hydren JR, Cornwell WK 3rd, Richardson RS, Drakos SG. Exercise Capacity in Mechanically Supported Advanced Heart Failure Patients: It Is All About the Beat. ASAIO J. 2020 Apr;66(4):339-342. PubMed PMID: 32221141
• McDonnell BJ, Rosenblum H, Cornwell WK 3rd, Kanwar M, Cockcroft JR, Stöhr EJ. Bionic women and men - Part 2: Arterial stiffness in heart failure patients implanted with left ventricular assist devices. Exp Physiol. 2020 May;105(5):755-758. PubMed PMID: 32144954
• Buchanan C, Kanwar M, Cockcroft JR, McDonnell B, Stöhr EJ, Cornwell WK 3rd. Bionic women and men - Part 4: Cardiovascular, cerebrovascular and exercise responses among patients supported with left ventricular assist devices. Exp Physiol. 2020 May;105(5):763-766. PubMed PMID: 32105385
• Stöhr EJ, Cornwell WK 3rd, Kanwar M, Cockcroft JR, McDonnell BJ. Bionic women and men - Part 1: Cardiovascular lessons from heart failure patients implanted with left ventricular assist devices. Exp Physiol. 2020 May;105(5):749-754. PubMed PMID: 32104940
• Kanwar M, McDonnell BJ, Rosenblum H, Cockcroft JR, Stöhr EJ, Cornwell WK 3rd. Bionic women and men - Part 3: Right ventricular dysfunction in patients implanted with left ventricular assist devices. Exp Physiol. 2020 May;105(5):759-762. PubMed PMID: 32103556
• Pal JD, Cleveland J, Reece BT, Byrd J, Pierce CN, Brieke A, Cornwell WK 3rd. Cardiac Emergencies in Patients with Left Ventricular Assist Devices. Heart Fail Clin. 2020 Jul;16(3):295-303. PubMed PMID: 32503753
• Cornwell WK, Tran T, Cerbin L, Coe G, Muralidhar A, Hunter K, Altman N, Ambardekar AV, Tompkins C, Zipse M, Schulte M, O'Gean K, Ostertag M, Hoffman J, Pal JD, Lawley JS, Levine BD, Wolfel E, Kohrt WM, Buttrick P. New insights into resting and exertional right ventricular performance in the healthy heart through real-time pressure-volume analysis. J Physiol. 2020 Jul;598(13):2575-2587. PubMed PMID: 32347547
• Buchanan C, Kanwar M, Cockcroft JR, McDonnell B, Stöhr EJ, Cornwell WK 3rd. Bionic women and men - Part 4: Cardiovascular, cerebrovascular and exercise responses among patients supported with left ventricular assist devices. Exp Physiol. 2020 May;105(5):763-766. PubMed PMID: 32105385
• Kanwar M, McDonnell BJ, Rosenblum H, Cockcroft JR, Stöhr EJ, Cornwell WK 3rd. Bionic women and men - Part 3: Right ventricular dysfunction in patients implanted with left ventricular assist devices. Exp Physiol. 2020 May;105(5):759-762. PubMed PMID: 32103556
• McDonnell BJ, Rosenblum H, Cornwell WK 3rd, Kanwar M, Cockcroft JR, Stöhr EJ. Bionic women and men - Part 2: Arterial stiffness in heart failure patients implanted with left ventricular assist devices. Exp Physiol. 2020 May;105(5):755-758. PubMed PMID: 32144954
• Stöhr EJ, Cornwell WK 3rd, Kanwar M, Cockcroft JR, McDonnell BJ. Bionic women and men - Part 1: Cardiovascular lessons from heart failure patients implanted with left ventricular assist devices. Exp Physiol. 2020 May;105(5):749-754. PubMed PMID: 32104940
• Hydren JR, Cornwell WK 3rd, Richardson RS, Drakos SG. Exercise Capacity in Mechanically Supported Advanced Heart Failure Patients: It Is All About the Beat. ASAIO J. 2020 Apr;66(4):339-342. PubMed PMID: 32221141
• Yancy CW, Drazner MH, Coffin ST, Cornwell W 3rd, Desai S, Erwin JP 3rd, Ginwalla M, Harshaw-Ellis KS, Horwich T, Kittleson M, Lala A, Lewsey SC, Marine JE, Martin CM, Meehan K, Morrow DA, Schlendorf K, Smith JW, Stevens GR. 2020 ACC/HFSA/ISHLT Lifelong Learning Statement for Advanced Heart Failure and Transplant Cardiology Specialists: A Report of the ACC Competency Management Committee. J Am Coll Cardiol. 2020 Mar 17;75(10):1212-1230. PubMed PMID: 32081442
• Yancy CW, Drazner MH, Coffin ST, Cornwell W 3rd, Desai S, Erwin JP 3rd, Ginwalla M, Harshaw-Ellis KS, Horwich T, Kittleson M, Lala A, Lewsey SC, Marine JE, Martin C, Meehan K, Morrow DA, Schlendorf K, Smith JW, Stevens GR, Arrighi JA, Mendes LA, Adams JE 3rd, Brush JE Jr, Dec GW Jr, Denktas A, Fernandes S, Freeman R, Francis SA, Hahn RT, Halperin JL, Housholder-Hughes SD, Khan SS, Klarich K, Lin CH, Marine JE, McPherson JA, Niazi K, Ryan T, Solomon MA, Spicer RL, Tam M, Wang A, Weissman G, Weitz HH, Williams ES. 2020 ACC/HFSA/ISHLT Lifelong Learning Statement for Advanced Heart Failure and Transplant Cardiology Specialists: A Report of the ACC Competency Management Committee. J Card Fail. 2020 Mar;26(3):254-269. PubMed PMID: 32081473
• Dias KA, Lawley JS, Gatterer H, Howden EJ, Sarma S, Cornwell WK 3rd, Hearon CM Jr, Samels M, Everding B, Liang AS, Hendrix M, Piper T, Thevis M, Bruick RK, Levine BD. Effect of acute and chronic xenon inhalation on erythropoietin, hematological parameters, and athletic performance. J Appl Physiol (1985). 2019 Dec 1;127(6):1503-1510. PubMed PMID: 31414957
• Lawley JS, Gatterer H, Dias KA, Howden EJ, Sarma S, Cornwell WK 3rd, Hearon CM Jr, Samels M, Everding B, Bruick RK, Hendrix M, Piper T, Thevis M, Levine BD. Safety, hemodynamic effects, and detection of acute xenon inhalation: rationale for banning xenon from sport. J Appl Physiol (1985). 2019 Dec 1;127(6):1511-1518. PubMed PMID: 31414955
• Flint KM, Brieke A, Cornwell WK 3rd, Pierce C, Cleveland JC, Pal JD. HeartMate II System Controller Failure Presenting as Driveline Fault With Repeated Pump Stoppages. Circ Heart Fail. 2019 Jul;12(7):e005738. PubMed PMID: 31213070
• Gopinathannair R, Cornwell WK, Dukes JW, Ellis CR, Hickey KT, Joglar JA, Pagani FD, Roukoz H, Slaughter MS, Patton KK. Device Therapy and Arrhythmia Management in Left Ventricular Assist Device Recipients: A Scientific Statement From the American Heart Association. Circulation. 2019 May 14;139(20):e967-e989. PubMed PMID: 30943783
• Wrobel CA, Drazner MH, Ayers CR, Pham DD, La Hoz RM, Grodin JL, Garg S, Mammen PPA, Morlend RM, Araj F, Amin AA, Cornwell WK 3rd, Thibodeau JT. Delayed febrile response with bloodstream infections in patients with continuous-flow left ventricular assist devices. J Investig Med. 2019 Mar;67(3):653-658. PubMed PMID: 30696751
• Cornwell WK 3rd, Ambardekar AV, Tran T, Pal JD, Cava L, Lawley J, Tarumi T, Cornwell CL, Aaronson K. Stroke Incidence and Impact of Continuous-Flow Left Ventricular Assist Devices on Cerebrovascular Physiology. Stroke. 2019 Feb;50(2):542-548. PubMed PMID: 30602359
• Cornwell WK 3rd, Tarumi T, Lawley J, Ambardekar AV. Rebuttal from William K. Cornwell III, Takashi Tarumi, Justin Lawley and Amrut V. Ambardekar. J Physiol. 2019 Jan;597(2):363-364. PubMed PMID: 30560588
• Petersen LG, Lawley JS, Lilja-Cyron A, Petersen JCG, Howden EJ, Sarma S, Cornwell WK 3rd, Zhang R, Whitworth LA, Williams MA, Juhler M, Levine BD. Lower body negative pressure to safely reduce intracranial pressure. J Physiol. 2019 Jan;597(1):237-248. PubMed PMID: 30286250
• Cornwell WK 3rd, Tarumi T, Lawley J, Ambardekar AV. CrossTalk opposing view: Blood flow pulsatility in left ventricular assist device patients is not essential to maintain normal brain physiology. J Physiol. 2019 Jan;597(2):357-359. PubMed PMID: 30560586
• Hieda M, Howden EJ, Sarma S, Cornwell W, Lawley JS, Tarumi T, Palmer D, Samels M, Everding B, Livingston S, Fu Q, Zhang R, Levine BD. The impact of 2 years of high-intensity exercise training on a model of integrated cardiovascular regulation. J Physiol. 2019 Jan;597(2):419-429. PubMed PMID: 30387144
• Purohit SN, Cornwell WK 3rd, Pal JD, Lindenfeld J, Ambardekar AV. Living Without a Pulse: The Vascular Implications of Continuous-Flow Left Ventricular Assist Devices. Circ Heart Fail. 2018 Jun;11(6):e004670. PubMed PMID: 29903893
• Howden EJ, Sarma S, Lawley JS, Opondo M, Cornwell W, Stoller D, Urey MA, Adams-Huet B, Levine BD. Reversing the Cardiac Effects of Sedentary Aging in Middle Age-A Randomized Controlled Trial: Implications For Heart Failure Prevention. Circulation. 2018 Apr 10;137(15):1549-1560. PubMed PMID: 29311053
• Luc JGY, Pierre CA, Phan K, Vahedein YS, Liberson AS, Cornwell WK, Phillips SJ, Tchantchaleishvili V. Fluid structure interaction model analysis of cerebrospinal fluid circulation in patients with continuous-flow left ventricular assist devices. Int J Artif Organs. 2017 Nov 16;:0. [Epub ahead of print] PubMed PMID: 29148023
• Gagnon D, Romero SA, Ngo H, Sarma S, Cornwell WK Rd, Poh PYS, Stoller D, Levine BD, Crandall CG. Volume loading augments cutaneous vasodilatation and cardiac output of heat stressed older adults. J Physiol. 2017 Oct 15;595(20):6489-6498. PubMed PMID: 28833129
• Patel AC, Dodson RB, Cornwell WK 3rd, Hunter KS, Cleveland JC Jr, Brieke A, Lindenfeld J, Ambardekar AV. Dynamic Changes in Aortic Vascular Stiffness in Patients Bridged to Transplant With Continuous-Flow Left Ventricular Assist Devices. JACC Heart Fail. 2017 Jun;5(6):449-459. PubMed PMID: 28285118
• Pandey A, Cornwell WK 3rd, Willis B, Neeland IJ, Gao A, Leonard D, DeFina L, Berry JD. Body Mass Index and Cardiorespiratory Fitness in Mid-Life and Risk of Heart Failure Hospitalization in Older Age: Findings From the Cooper Center Longitudinal Study. JACC Heart Fail. 2017 May;5(5):367-374. PubMed PMID: 28396043
• Lawley JS, Petersen LG, Howden EJ, Sarma S, Cornwell WK, Zhang R, Whitworth LA, Williams MA, Levine BD. Effect of gravity and microgravity on intracranial pressure. J Physiol. 2017 Mar 15;595(6):2115-2127. PubMed PMID: 28092926
• Lawley JS, Petersen LG, Howden EJ, Sarma S, Cornwell WK, Zhang R, Whitworth LA, Williams MA, Levine BD. Effect of gravity and microgravity on intracranial pressure. J Physiol. 2017 Jan 16. [Epub ahead of print] PubMed PMID: 28092926
• Gagnon D, Romero SA, Ngo H, Sarma S, Cornwell WK 3rd, Poh PY, Stoller D, Levine BD, Crandall CG. Healthy aging does not compromise the augmentation of cardiac function during heat stress. J Appl Physiol (1985). 2016 Oct 1;121(4):885-892. PubMed PMID: 27609201
• Gagnon D, Romero SA, Ngo H, Sarma S, Cornwell WK 3rd, Poh PY, Stoller D, Levine BD, Crandall CG. Healthy aging does not compromise the augmentation of cardiac function during heat stress. J Appl Physiol (1985). 2016 Oct 1;121(4):885-892. PubMed PMID: 27609201
• Darsaklis K, Dickson ME, Cornwell W 3rd, Ayers CR, Torres F, Chin KM, Matulevicius S. Right atrial emptying fraction non-invasively predicts mortality in pulmonary hypertension. Int J Cardiovasc Imaging. 2016 Jul;32(7):1121-30. PubMed PMID: 27076226
• Cornwell WK 3rd, Tarumi T, Stickford A, Lawley J, Roberts M, Parker R, Fitzsimmons C, Kibe J, Ayers C, Markham D, Drazner MH, Fu Q, Levine BD. Restoration of Pulsatile Flow Reduces Sympathetic Nerve Activity Among Individuals With Continuous-Flow Left Ventricular Assist Devices. Circulation. 2015 Dec 15;132(24):2316-22. PubMed PMID: 26510698
• Cornwell WK 3rd, Urey M, Drazner MH, Levine BD. Continuous-Flow Circulatory Support: The Achilles Heel of Current-Generation Left Ventricular Assist Devices?. Circ Heart Fail. 2015 Sep;8(5):850-2. PubMed PMID: 26374917
• Cornwell WK 3rd, Levine BD. Patients with heart failure with reduced ejection fraction have exaggerated reductions in cerebral blood flow during upright posture. JACC Heart Fail. 2015 Feb;3(2):176-9. PubMed PMID: 25543968
• Garg S, Ayers CR, Fitzsimmons C, Meyer D, Peltz M, Bethea B, Cornwell W, Araj F, Thibodeau J, Drazner MH. In-hospital cardiopulmonary arrests in patients with left ventricular assist devices. J Card Fail. 2014 Dec;20(12):899-904. PubMed PMID: 25463416
• Cornwell WK 3rd, Tarumi T, Aengevaeren VL, Ayers C, Divanji P, Fu Q, Palmer D, Drazner MH, Meyer DM, Bethea BT, Hastings JL, Fujimoto N, Shibata S, Zhang R, Markham DW, Levine BD. Effect of pulsatile and nonpulsatile flow on cerebral perfusion in patients with left ventricular assist devices. J Heart Lung Transplant. 2014 Dec;33(12):1295-303. PubMed PMID: 25307621
• Levine BD, Cornwell WK 3rd, Drazner MH. Factors influencing the rate of flow through continuous-flow left ventricular assist devices at rest and with exercise. JACC Heart Fail. 2014 Aug;2(4):331-4. PubMed PMID: 25023819
• McLaughlin VV, Davis M, Cornwell W. Pulmonary arterial hypertension. Curr Probl Cardiol. 2011 Dec;36(12):461-517. PubMed PMID: 22035608
• Cornwell WK, McLaughlin VV, Krishnan SM, Rubenfire M. Does the outcome justify an oral-first treatment strategy for management of pulmonary arterial hypertension?. Chest. 2011 Sep;140(3):697-705. PubMed PMID: 21622545
• Tong GC, Cornwell WK, Means GE. Reactions of acrylamide with glutathione and serum albumin. Toxicol Lett. 2004 Mar 1;147(2):127-31. PubMed PMID: 14757316

Practice Locations

UCHealth Heart & Vascular Center - Anschutz
12505 E. 16th Ave
Anschutz Inpatient Pavilion 2, 3rd floor
Aurora, CO 80045
720-848-5300

UCHealth Heart Failure Program - Anschutz
12505 E. 16th Ave
Anschutz Inpatient Pavilion 2, 3rd floor
Aurora, CO 80045
720-848-5300

CU Medicine Cardiology - Cherry Creek Medical Center
100 Cook Street
Suite 412
Denver, CO 80206
720-516-9403

Hospital Affiliation

• University of Colorado Hospital

Center Affiliations

• Colorado Clinical & Translational Sciences Institute (CCTSI)
• University of Colorado Cardiovascular Institute

Specialty Information

Specialties

• General Cardiology, Board Certification
• Advanced Heart Failure and Transplant Cardiology, Board Certification
• Sports Medicine, Board Certification

Conditions & Treatments

• Heart and Circulation
• Heart and Circulation - Cardiomyopathy
• Heart and Circulation - Circulatory Disorders
• Heart and Circulation - Coronary Disease
• Heart and Circulation - Heart Attack
• Heart and Circulation - Heart Failure
• Heart and Circulation - Structural Heart Disease
• Surgery - Heart Transplant Surgery
• Surgery