James Pomposelli, MD, PhD
Professor, Surgery-Transplant

Professional Titles

• Professor of Surgery
• Surgical Director of Liver Transplantation

Recognition & Awards

• Guide to Americas Best Surgeons, Consumers' Research Council of America (2016)
• Outstanding Teacher Award, Third Year Medical Students, Tufts Medical School (2015)
• Outstanding Teacher Award, Third Year Medical Students, Tufts Medical School (2014)
• Visiting Professor in Transplantation, Department of Transplantation, University of Pennsylvania (2014)
• Guide to Americas Best Surgeons, Consumers' Research Council of America (2013)
• America’s Best Doctors, U.S. News (2011)
• Outstanding Teacher Award, Third Year Medical Students, Tufts Medical School (2008)
• Outstanding Teacher Award, Third Year Medical Students, Tufts Medical School (2007)
• Selected to Vanguard Committee, American Society of Transplant Surgeons (2006)
• Outstanding Teacher Award, Third Year Medical Students, Tufts Medical School (2006)
• Selected to Vanguard Committee, American Society of Transplant Surgeons (2005)
• Selected to Vanguard Committee, American Society of Transplant Surgeons (2004)
• Distinguished Visiting Professor, Division of Vascular Surgery, Washington Hospital Center (2004)
• Selected to Vanguard Committee, American Society of Transplant Surgeons (2003)
• Young Surgeon Travel Award, 96th Annual Congress, Japan Surgical Society (1996)
  Paper Presentation “Work of breathing as a criteria for weaning ventilator dependent patients.”
• Stanley Dudrick Research Scholar Award Finalist, American Society of Enteral and Parenteral Nutrition (1992)
• Charles E. Culpepper Research Fellow, Charles E. Culpepper Foundation (1990)
• Stanley Dudrick Research Scholar Award Finalist, American Society of Enteral and Parenteral Nutrition. (1990)
• Harry M. Vars Research Award Finalist, American Society of Enteral and Parenteral Nutrition (1989)
• Charles E. Culpepper Research Fellow, Charles E. Culpepper Foundation (1989)
• Alpha Omega Alpha, Boston University School of Medicine (1989)
• Harry M. Vars Research Award Finalist, American Society of Enteral and Parenteral Nutrition (1988)
• American Institute of Nutrition (FASEB/AIN) Graduate Student Research Award, Federation of American Societies for Experimental Biology (1988)
• Charles E. Culpepper Research Fellow, Charles E. Culpepper Foundation (1988)
• Harry M. Vars Research Award Finalist, American Society of Enteral and Parenteral Nutrition (1987)

Research Interests

Publications

• Jonica ER, Han S, Burton JR Jr, Pomposelli JJ, Shah RJ. Choledochoduodenostomy is associated with fewer post-transplant biliary complications compared to Roux-en-Y in primary sclerosing cholangitis patients. Clin Transplant. 2022 Jan 19;:e14597. [Epub ahead of print] PubMed PMID: 35043996
• Jonica ER, Han S, Burton JR Jr, Pomposelli JJ, Shah RJ. Choledochoduodenostomy is associated with fewer post-transplant biliary complications compared to Roux-en-Y in primary sclerosing cholangitis patients. Clin Transplant. 2022 May;36(5):e14597. PubMed PMID: 35043996
• Moore HB, Bababekov YJ, Pomposelli JJ, Adams MA, Crouch C, Yoeli D, Choudhury RA, Ferrell T, Burton JR, Pomfret EA, Nydam TL. The vexing triad of obesity, alcohol, and coagulopathy predicts the need for multiple operations in liver transplantation. Am J Surg. 2022 Jul;224(1 Pt A):69-74. PubMed PMID: 35227491
• Cheah YL, Heimbach J, Kwon CHD, Pomposelli J, Rudow DL, Broering D, Spiro M, Raptis DA, Roberts JP. Influence of surgical technique in donor hepatectomy on immediate and short-term living donor outcomes - A systematic review of the literature, meta-analysis, and expert panel recommendations. Clin Transplant. 2022 Oct;36(10):e14703. PubMed PMID: 35538019
• Jackson WE, Malamon JS, Kaplan B, Saben JL, Schold JD, Pomposelli JJ, Pomfret EA. Survival Benefit of Living-Donor Liver Transplant. JAMA Surg. 2022 Oct 1;157(10):926-932. PubMed PMID: 35921119
• Jiang JG, Ferrell T, Sauaia A, Rodriguez IE, Yoeli D, Nydam TL, Kennealey PT, Pomposelli JJ, Pomfret EA, Moore HB. Low viscoelastic clot strength, platelet transfusions, and graft dysfunction are associated with persistent postoperative ascites following liver transplantation. Am J Surg. 2022 Dec;224(6):1432-1437. PubMed PMID: 36216610
• Stewart E, Nydam TL, Hendrickse A, Pomposelli JJ, Pomfret EA, Moore HB. Viscoelastic Management of Coagulopathy during the Perioperative Period of Liver Transplantation. Semin Thromb Hemost. 2022 Nov 1. [Epub ahead of print] PubMed PMID: 36318962
• Truong R, Moore HB, Sauaia A, Kam I, Pshak T, Adams M, Conzen K, Zimmerman MA, Wachs M, Bak T, Pomposelli J, Pomfret E, Nydam TL. Choledochoduodenostomy continues to be a safe alternative for biliary reconstruction in deceased-donor liver transplantation. Am J Surg. 2022 Dec;224(6):1398-1402. PubMed PMID: 36400602
• Heimbach JK, Trotter JF, Pomposelli J, Cafarella M, Noreen SM. A Tale Full of Sound and Fury. Liver Transpl. 2021 Jan 18. [Epub ahead of print] PubMed PMID: 33458925
• Jackson WE, Kriss MS, Burton JR Jr, Nydam TL, Conzen KD, Pomposelli JJ, Pomfret EA. Reply to "Living liver donation in previous kidney donors: A single-center experience". Am J Transplant. 2021 Jan;21(1):435-437. PubMed PMID: 32558135
• Yoeli D, Jackson WE, Adams MA, Wachs ME, Sundaram SS, Sater A, Cisek JR, Choudhury RA, Nydam TL, Pomposelli JJ, Conzen KD, Kriss MS, Burton JR Jr, Pomfret EA. Challenging the Traditional Paradigm of Supply and Demand in Pediatric Liver Transplantation Through Nondirected Living Donation: A Case Series. Liver Transpl. 2021 Oct;27(10):1392-1400. PubMed PMID: 34048131
• Heimbach JK, Trotter JF, Pomposelli J, Cafarella M, Noreen SM. A Tale Full of Sound and Fury. Liver Transpl. 2021 May;27(5):624-626. PubMed PMID: 33458925
• Yoeli D, Choudhury RA, Nydam TL, Pomposelli JJ, Goss JA, Pomfret EA, Wachs ME, Adams MA. The Surge in Deceased Liver Donors Due to the Opioid Epidemic: Is It Time to Split the Difference?. Transplantation. 2021 Oct 1;105(10):2239-2244. PubMed PMID: 33065726
• Jackson WE, Kriss MS, Burton JR Jr, Nydam TL, Conzen KD, Pomposelli JJ, Pomfret EA. Reply to "Living liver donation in previous kidney donors: A single-center experience". Am J Transplant. 2021 Jan;21(1):435-437. PubMed PMID: 32558135
• Choudhury RA, Foster M, Hoeltzel G, Moore HB, Yaffe H, Yoeli D, Prins K, Ghincea C, Vigneshwar N, Dumon KR, Rame JE, Conzen KD, Pomposelli JJ, Pomfret EA, Nydam TL. Bariatric Surgery for Congestive Heart Failure Patients Improves Access to Transplantation and Long-term Survival. J Gastrointest Surg. 2021 Apr;25(4):926-931. PubMed PMID: 32323251
• Yoeli D, Choudhury RA, Nydam TL, Pomposelli JJ, Goss JA, Pomfret EA, Wachs ME, Adams MA. The Surge in Deceased Liver Donors Due to the Opioid Epidemic: Is it Time to Split the Difference?. Transplantation. 2020 Oct 12. [Epub ahead of print] PubMed PMID: 33065726
• Choudhury RA, Yoeli D, Dagan A, Yaffe H, Moore HB, Conzen KD, Adams M, Wachs M, Pomposelli JJ, Pomfret EA, Nydam TL. Offspring to Parent LDLT: Narrowing the Gap Between Theory and Evidence. Transplantation. 2020 Oct;104(10):e307. PubMed PMID: 32969991
• Hughes DL, Rice JD, Burton JR, Jin Y, Peterson RA, Ambardekar AV, Pomposelli JJ, Pomfret EA, Kriss MS. Presence of any degree of coronary artery disease among liver transplant candidates is associated with increased rate of post-transplant major adverse cardiac events. Clin Transplant. 2020 Nov;34(11):e14077. PubMed PMID: 32939833
• Schulick AC, Moore HB, Walker CB, Yaffe H, Pomposelli JJ, Azam F, Wachs M, Bak T, Kennealey P, Conzen K, Adams M, Pshak T, Choudhury R, Chapman MP, Pomfret EA, Nydam TL. A clinical coagulopathy score concurrent with viscoelastic testing defines opportunities to improve hemostatic resuscitation and enhance blood product utilization during liver transplantation. Am J Surg. 2020 Dec;220(6):1379-1386. PubMed PMID: 32907709
• Moore HB, Yaffe H, Pomposelli JJ, Wachs M, Bak T, Kennealey P, Conzen K, Adams M, Pshak T, Choudhury R, Walker C, Schulick A, Ferrell T, Chapman MP, Pomfret EA, Nydam TL. Detection of early allograft dysfunction at 30 min of reperfusion in liver transplantation: An intraoperative diagnostic tool with real time assessment of graft function. Am J Surg. 2020 Dec;220(6):1518-1525. PubMed PMID: 32907708
• Walker CB, Moore HB, Nydam TL, Schulick AC, Yaffe H, Pomposelli JJ, Wachs M, Bak T, Conzen K, Adams M, Pshak T, Choudhury R, Chapman MP, Pomfret EA, Kennealey P. The use of thromboelastography to assess post-operative changes in coagulation and predict graft function in renal transplantation. Am J Surg. 2020 Dec;220(6):1511-1517. PubMed PMID: 32878689
• Choudhury RA, Foster M, Hoeltzel G, Moore HB, Yaffe H, Yoeli D, Prins K, Ghincea C, Vigneshwar N, Dumon KR, Rame JE, Conzen KD, Pomposelli JJ, Pomfret EA, Nydam TL. Bariatric Surgery for Congestive Heart Failure Patients Improves Access to Transplantation and Long-term Survival. J Gastrointest Surg. 2020 Apr 22. [Epub ahead of print] PubMed PMID: 32323251
• Bababekov YJ, Hung YC, Chang DC, Rickert CG, Adler JT, Bethea E, Pomfret EA, Pomposelli JJ, Yeh H. Do Social Determinants Define "Too Sick" to Transplant in Patients With End-stage Liver Disease?. Transplantation. 2020 Feb;104(2):280-284. PubMed PMID: 31335769
• Dagan A, Choudhury RA, Yaffe H, Yoeli D, Moore HB, Conzen KD, Adams M, Wachs M, Pomposelli JJ, Pomfret EA, Nydam TL. Offspring Versus Nonoffspring to Parent Living Donor Liver Transplantation: Does Donor Relationship Matter?. Transplantation. 2020 May;104(5):996-1002. PubMed PMID: 31568397
• Kim D, Bolus C, Iqbal S, Pomposelli J, Flacke S. Percutaneous Creation of Intrahepatic Biliary Tract for Treatment of Posthepatectomy Excluded Segmental Bile Duct Leak. J Vasc Interv Radiol. 2018 Dec;29(12):1770-1772. PubMed PMID: 30502880
• Bababekov YJ, Hung YC, Rickert CG, Njoku FC, Cao B, Adler JT, Brega AG, Pomposelli JJ, Chang DC, Yeh H. Health Literacy Burden Is Associated with Access to Liver Transplantation. Transplantation. 2018 Nov 13. [Epub ahead of print] PubMed PMID: 30431496
• Leppard W, Pomposelli T, Chang EI, Suliman A, Herrera F. Internal mammary usability as recipient vessels in DIEP breast reconstruction in the setting of previous radiation. J Plast Reconstr Aesthet Surg. 2018 Aug;71(8):1123-1128. PubMed PMID: 29933915
• Rivard CJ, Tanabe T, Lanaspa MA, Watanabe H, Nomura S, Andres-Hernando A, Garth K, Sekijima M, Ishimoto T, Ariyoshi Y, Garcia GE, Shah J, Lennan B, Tasaki M, Pomposelli T, Shimizu A, Sachs DH, Johnson RJ, Yamada K. Upregulation of CD80 on glomerular podocytes plays an important role in development of proteinuria following pig-to-baboon xeno-renal transplantation - an experimental study. Transpl Int. 2018 Oct;31(10):1164-1177. PubMed PMID: 29722117
• Bababekov YJ, Nydam TL, Pomposelli JJ, Moore HB. Goal-directed Management of Coagulation: The Right Treatment, the Right Patient, the Right Time. Transplantation. 2018 Jun;102(6):e303-e304. PubMed PMID: 29557909
• Fiz F, Villa G, Ferrari E, Pomposelli E, Morbelli S, Alloisio A, Pende D, Meazza R, Gereloni C, Marini C, Ratto GB, Sambuceti G. Prevention of systemic toxicity in hyperthermic isolated lung perfusion using radioisotopic leakage monitoring. Int J Hyperthermia. 2018 Jun;34(4):469-478. PubMed PMID: 28705098
• Bababekov YJ, Ven Fong Z, Chang DC, Simpson MA, Yeh H, Pomposelli JJ. Is liver transplant education patient-centered?. Liver Transpl. 2017 Aug;23(8):1070-1072. PubMed PMID: 28618164
• Baker TB, Zimmerman MA, Goodrich NP, Samstein B, Pomfret EA, Pomposelli JJ, Gillespie BW, Berg CL, Emond JC, Merion RM. Biliary reconstructive techniques and associated anatomic variants in adult living donor liver transplantations: The adult-to-adult living donor liver transplantation cohort study experience. Liver Transpl. 2017 Dec;23(12):1519-1530. PubMed PMID: 28926171
• Emond JC, Goodrich NP, Pomposelli JJ, Baker TB, Humar A, Grant DR, Abt P, Friese CE, Fisher RA, Kam I, Sherker AH, Gillespie BW, Merion RM. Hepatic Hemodynamics and Portal Flow Modulation: The A2ALL Experience. Transplantation. 2017 Oct;101(10):2375-2384. PubMed PMID: 28514251
• Bababekov YJ, Pomposelli JJ, Yeh H, Rudd RE, Chang DC. Surgical Outcomes: Shifting the Focus From Measurement to Improvement. Ann Surg. 2017 Dec;266(6):e103-e104. PubMed PMID: 27043741
• Pomposelli JJ. Hepatic Artery Thrombosis After Liver Transplant: Not A Surgical Problem?. Transplantation. 2016 Nov;100(11):2251. PubMed PMID: 27547869
• Pomposelli JJ, Goodrich NP, Emond JC, Humar A, Baker TB, Grant DR, Fisher RA, Roberts JP, Olthoff KM, Gillespie BW, Merion RM. Patterns of Early Allograft Dysfunction in Adult Live Donor Liver Transplantation: The A2ALL Experience. Transplantation. 2016 Jul;100(7):1490-9. PubMed PMID: 27326811
• Bababekov YJ, Pomposelli JJ, Yeh H, Rudd RE, Chang DC. Surgical Outcomes: Shifting the Focus From Measurement to Improvement. Ann Surg. 2016 Mar 31. [Epub ahead of print] PubMed PMID: 27043741
• Genyk Y, Kato T, Pomposelli JJ, Wright JK Jr, Sher LS, Tetens V, Chapman WC. Fibrin Sealant Patch (TachoSil) vs Oxidized Regenerated Cellulose Patch (Surgicel Original) for the Secondary Treatment of Local Bleeding in Patients Undergoing Hepatic Resection: A Randomized Controlled Trial. J Am Coll Surg. 2016 Mar;222(3):261-8. PubMed PMID: 26776356

Professional Memberships

• American Society of Transplant Surgeons, Co-Chair Legislative and Regulatory Committee
• Massachusetts Medical Society, Member
• Alpha Omega Alpha, Boston Chapter, Member
• American College of Surgeons, Member
• New England Surgical Society, Member
• Boston Surgical Society, Member
• American Liver Foundation, Member
• American Society of Transplant Surgeons, Member
• International Liver Transplant Society, Member