Anandani Nellan, MD, MPH

Assistant Adjoint Professor, Pediatrics


FacultyPhoto
Department
Pediatrics

Publications

  • Nellan A, McCully CML, Cruz Garcia R, Jayaprakash N, Widemann BC, Lee DW, Warren KE. Improved CNS exposure to tocilizumab after cerebrospinal fluid compared to intravenous administration in rhesus macaques. Blood. 2018 Aug 9;132(6):662-666. PubMed PMID: 29954750
  • Nellan A, Rota C, Majzner R, Lester-McCully CM, Griesinger AM, Mulcahy Levy JM, Foreman NK, Warren KE, Lee DW. Durable regression of Medulloblastoma after regional and intravenous delivery of anti-HER2 chimeric antigen receptor T cells. J Immunother Cancer. 2018 Apr 30;6(1):30. PubMed PMID: 29712574
  • Witt DA, Donson AM, Amani V, Moreira DC, Sanford B, Hoffman LM, Handler MH, Levy JMM, Jones KL, Nellan A, Foreman NK, Griesinger AM. Specific expression of PD-L1 in RELA-fusion supratentorial ependymoma: Implications for PD-1-targeted therapy. Pediatr Blood Cancer. 2018 May;65(5):e26960. PubMed PMID: 29350470
  • Manuscript Number: CCR-18-0432R Manuscript Type: Research Article: Cancer Therapy: Preclinical Manuscript Title: CAR T cells targeting B7-H3, a Pan-Cancer Antigen, Demonstrate Potent Preclinical Activity Against Pediatric Solid Tumors and Brain Tumors Corresponding Author: Dr. Mackall Full Author List: Robbie Majzner, Johanna Theruvath, Anandani Nellan, Sabine Heitzeneder, Yongzhi Cui, Christopher Mount, Skyler Rietberg, Miles Linde, Peng Xu, Christopher Rota, Elena Sotillo, Louai Labanieh, Daniel Lee, Rimas Orentas, Dimiter Dimitrov, Zhongyu Zhu, Brad St. Croix, Alberto Delaidelli, Alla Sekunova, Ezio Bonvini, Siddhartha Mitra, Martha Quezado, Ravindra Majeti, Michelle Monje, Poul Sorensen, John Maris, and Crystal Mackall
  • Robbie G. Majzner, Johanna L. Theruvath†, Anandani Nellan†, Sabine Heitzeneder†, Yongzhi K. Cui, Christopher Mount, Skyler P. Rietberg, Miles H. Linde, Peng Xu, Christopher Rota, Elena Sotillo, Louai Labanieh, Daniel W. Lee, Rimas J. Orentas, Dimiter S. Dimitrov, Zhongyu Zhu, Brad St Croix, Alberto Delaidelli, Alla Sekunova, Ezio Bonvini, Siddhartha S. Mitra, Martha Quezado, Ravindra Majeti, Michelle Monje, Poul H. Sorensen, John M. Maris, and Crystal L. Mackall. CAR T cells targeting B7-H3, a Pan-Cancer Antigen, Demonstrate Potent Preclinical Activity Against Pediatric Solid Tumors and Brain Tumors. Clinical Cancer Research, 2019. https://doi.org/10.1158/1078-0432.CCR-18-0432
  • Jessica A. Lake, Andrew M. Donson, Eric Prince, Kurtis D. Davies, Anandani Nellan, Adam L. Green, Jean Mulcahy Levy, Kathleen Dorris, Rajeev Vibhakar, Todd C. Hankinson, Nicholas K. Foreman, Mark D. Ewalt, Bette K. Kleinschmidt-DeMasters, Lindsey M. Hoffman, Ahmed Gilani. "Targeted fusion analysis can aid in the classification and treatment of pediatric glioma, ependymoma, and glioneuronal tumors." Pediatric blood & cancer (2019): e28028. https://doi.org/10.1002/pbc.28028
  • Shadi Zahedi, Brent E. Fitzwalter, Andrew Morin, Sydney Grob, Michele Desmarais, Anandani Nellan, Adam L. Green Rajeev Vibhakar, Todd C. Hankinson, Nicholas K. Foreman & Jean M. Mulcahy Levy. "Effect of early-stage autophagy inhibition in BRAF V600E autophagy-dependent brain tumor cells." Cell death & disease 10, no. 9 (2019): 1-15.
  • Grob ST, Nobre L, Campbell KR, Davies KD, Ryall S, Aisner DL, Hoffman L, Zahedi S, Morin A, Crespo M, Nellan A, Green AL, Foreman N, Vibhakar R, Hankinson TC, Handler MH, Hawkins C, Tabori U, Kleinschmidt-DeMasters BK, Mulcahy Levy JM. Clinical and molecular characterization of a multi-institutional cohort of pediatric spinal cord low-grade gliomas. Neurooncol Adv. 2020 Jan-Dec;2(1):vdaa103. PubMed PMID: 33063010
  • Nellan A, Bodlak A, Mirsky DM, Mulcahy Levy J, Garrington TP, Foreman NK, Gilani A, Hayashi M. ddPCR Analysis Reveals BRAF V600E Mutations Are Infrequent in Isolated Pituitary Langerhans Cell Histiocytosis Patients. J Neuropathol Exp Neurol. 2020 Sep 15. [Epub ahead of print] PubMed PMID: 32930721
  • Nellan A, Wright E, Campbell K, Davies KD, Donson AM, Amani V, Judd A, Hemenway MS, Raybin J, Foreman NK, Rush S, Dorris K. Retrospective analysis of combination carboplatin and vinblastine for pediatric low-grade glioma. J Neurooncol. 2020 Jul;148(3):569-575. PubMed PMID: 32506370
  • Lake JA, Donson AM, Prince E, Davies KD, Nellan A, Green AL, Mulcahy Levy J, Dorris K, Vibhakar R, Hankinson TC, Foreman NK, Ewalt MD, Kleinschmidt-DeMasters BK, Hoffman LM, Gilani A. Targeted fusion analysis can aid in the classification and treatment of pediatric glioma, ependymoma, and glioneuronal tumors. Pediatr Blood Cancer. 2020 Jan;67(1):e28028. PubMed PMID: 31595628
  • Nellan, A., Fry, T.J. Optimizing CARs for ocular delivery. Nat Cancer 1, 939–940 (2020). https://doi.org/10.1038/s43018-020-00127-y

Practice Locations

Children's Hospital Colorado Anschutz Medical Campus
13123 East 16th Ave
Aurora, CO 80045
720-777-1234

Specialty Information

Specialties
  • Pediatric Hematology / Oncology, Board Certification
Clinical Interests
I moved to Colorado for a clinical fellowship in Neuro-oncology after completing my training in Pediatric Hematology and Oncology at the combined training program at Johns Hopkins University/National Cancer Institute. I joined the faculty here as a clinician and researcher. I care for children and young adults with brain and spine tumors.

Care Philosophy
The physical and psychological impact of tumors on a patient can vary greatly based on age, tumor type and necessary treatment. I hope to offer patients and their families the most current therapeutic options, working alongside an excellent multi-disciplinary team here at Children's Hospital Colorado.

Personal Interests
Yoga, travel, reading, and spending time with my family.