Virginia Borges, MD

Menter A, Urquhart A, Borges VF, Rabinovitch R, Singh M, Robinson W, Seligman P, Finlayson C, Elias A. Second Opinion: A Woman with Primary Breast Cancer and a Solitary Sternal Metastasis. Oncology 2006 20(9) 1068-1080

Microenvironment of the Involuting Mammary Gland Mediates Mammary Cancer Progression. J Mammary Gland Biol Neoplasia. 2007 Feb 21; [Epub ahead of print] PMID: 17318269 [PubMed - as supplied by publisher]

Borges VF and Taylor CW. Breast Cancer Diagnosis, Risk Assessment and Management. University of Arizona College of Medicine and the University of Arizona Cancer Center. Web-based on-line CME education tool; March 2005: Editor. Updated 2006

Pegram MD, Borges V, Fuloria J, Ibrahim N, Shapiro C, Perez ES, Wang K, Schaedeli-Stark F, Yeon C, Courtney-Luck N, Phase I pharmacokinetics of humanized anti-MUC1 antibody R1550 ASCO 2006 #

A. Schwer, V. Borges, M. Ding, B. D. Kavanagh, The Norton-Simon Hypothesis Applied to Murine and Human Tumor Growth: Implications for Patient Selection in Stereotactic Body Radiation Therapy (SBRT) ASTRO 2006, Abstract # 2698

Borges V and Hardesty L, "Cost Effective Staging for Breast Cancer" in Early Diagnosis of Breast Cancer, Elsevier Press

Munson S, Parker J, King T, Lu Y, Kelley V, Guo Z, Borges V, and Franzusoff A. Coupling Innate and Adaptive Immunity with Yeast-based Cancer Immunotherapy. Cancer Vaccines and Tumor Immunity, 1. Edition - March 2008. ISBN-10: 0-470-07474-4, ISBN-13: 978-0-470-07474-9 - John Wiley & Sons

Harvell, DE, Spoelstra N, Singh M, McManaman J, Finlayson C, Phang T, Trapp S, Hunter L, Dye W, Borges VF, Elias AD, Horwitz K. Molecular signatures of neoadjuvant endocrine therapy for breast cancer: characteristics of response or intrinsic resistance. Accepted to Breast Cancer Research and Treatment

Kabos P and Borges VF. "Surveillence and Detection for the Recurrence of Breast Cancer" in Early Diagnosis of Breast Cancer, Elesevier Press

Amaria R, Corboy J, Finlayson C, Robinson W, Borges V. Immunomodulatory therapy in Multiple Sclerosis and Breast Cancer Risk: A Case Report and Literature Review. Clin Breast Can. Vol 8, No 5, Oct 2008

9. Pories S, Zurakowski D, Roy R, Lamb C, Raza R, Exarhopoulos A, Scheib R, Schumer S, Lenahan C, Borges V, Louis A, Anand A, Isakovich N, Hirshfield-Bartek J, Wewer U, Lotz MM, Moses MA. Urinary Metalloproteinases: Noninvasive Biomarkers for Breast Cancer Risk Assessment. Cancer Epidemiol Biomarkers Prev 2008;17(5).

Diamond J, Finlayson C, Borges V. Hepatic complications of breast cancer. Lancet Oncology, accepted 1/2009, print pending

Breaking down barriers: the importance of the stromal microenvironment in acquiring invasiveness in young women's breast cancer. Pepper Schedin and Virginia Borges, Breast Cancer Research, in press

Pegram MD, Borges V, Ibrahim N, Fuloria J, Shapiro C, Perez S, Wang K, Schaedeli Stark F, Courtenay Luck N. Phase I dose escalation pharmacokinetic assessment of intravenous humanized anti-MUC1 antibody AS1402 in patients with advanced breast cancer. Breast Cancer Res. 2009 Oct 7;11(5):R73. PMID: 19811637

Diamond JR, Finlayson CA, Thienelt C, Kabos P, Hardesty L, Barbour L, Klein CE, Rabinovitch R, Elias A, Borges VF, Early-Stage BRCA2-Linked Breast Cancer Diagnosed in the First Trimester of Pregnancy Associated With a Hypercoagulable State ONCOLOGY, 2009;23(9)

Nunes RA, Li X, Kang SP, Burstein H, Roberts L, Carney W, Blackwell K, Ryan P, Borges V, Iglehart JD, Friedman P, Harris LN., Circulating tumor cells in HER-2 positive metastatic breast cancer patients treated with trastuzumab and chemotherapy. Int J Biol Markers. 2009 Jan-Mar;24(1):1-10.

Lyons T, Schedin PJ, and Borges VF, Pregnancy and Breast Cancer: when they collide. Journal of Mammary Gland Biology and Neoplasia, J Mammary Gland Biol Neoplasia. 2009 Jun;14(2):87-98. Epub 2009 Apr 21

Jenean O’Brien, Traci Lyons, Jenifer Monks,M. Scott Lucia, R. Storey Wilson, Lisa Hines,Yan-gao Man, Virginia Borges,and Pepper Schedin. Alternatively Activated Macrophages and Collagen Remodeling Characterize the Postpartum Involuting Mammary Gland across Species, The American Journal of Pathology, Vol. 176, No. 3, March 2010

Kabos, P and Borges, V. Fulvestrant: a unique anti-endocrine agent for estrogen-sensitive breast cancer. Expert Opinion in Pharmacotherapy, Accepted Jan 2010

Hirsch FR, Mok TS, Borges V, Bunn PA, Molecularly targeted therapy: when to stop and when to continue? The Lancet Oncology 2010 Aug;11(8): 709-711. doi:10.1016/S1470-2045(10)70128-5

Kabos P and Borges VF. Fulvestrant; a unique antiendocrine agent for estrogen-sensitive breast cancer. Expert Opin Pharm April 2010; 11(5):807-816.

Kabos P and Borges VF. Surveillance and Detection for the Recurrence of Breast Cancer. Early Diagnosis and Treatment of Cancer: Breast Cancer, 1st Edition, 2010. ISBN 978-1-4160-4932-6, Saunders Elsevier

Borges V and Hardesty L. Cost Effective Staging for Breast Cancer. Early Diagnosis and Treatment of Cancer: Breast Cancer, 1st Edition, 2010. ISBN 978-1-4160-4932-6, Saunders Elsevier

Lyons T*, O’Brien J*, Monks J, Lucia MS, Wilson RS, Hines L, Man YM, Borges V, and Schedin PJ. “Alternatively activated macrophages and collagen remodeling characterize the post-partum involuting mammary gland across species.” Am J Pathol. 2010 Mar;176(3):1241-55. Epub 2010 Jan 28 *these authors contributed equally

Lyons TR, O’Brien J, Borges VF, Keely PJ, Conklin MW, Eliceiri KW, Marusyk A, Tan AC, and Schedin PJ. Postpartum mammary gland involution drives DCIS progression through collagen and COX-2, Nature Medicine, 2011 Sep 17(9):1109.

Jindal S, Borges VF. The Emerging role of Cytokines in Breast Cancer: From Initiation to Survivorship. Current Medical Literature, Vol 23, No 4, 2011

Borges VF, Schedin P, Pregnancy-Associated Breast Cancer: An Entity Needing Refinement of the Definition. Cancer, 2011, DOI 10.1002/cncr 266643

Borges V and Elias A. The Era of High-Dose Chemotherapy for Breast Cancer: Revisiting a Troubled Quest. The Journal of Clinical Oncology 2011 Aug 21; 29 (24): 3205-3206.

Kounalakis, N, Diamond J, Rusthoven K, Horn W, Jindal S, Wisell J, Klein CE, Elias A, Finlastono C, Borges V. Diagnosis of Invasive Lobular Carcinoma in a Young Woman Presenting with Pleomorphic Lobular Carcinoma in situ on Core Biopsy. Oncology April 2011, Vol 25(4).

Borges VF, Schedin, P. Could NSAIDS become a preventative therapy in pregnancy-associated breast cancer?. Breast Cancer Management (2012) 1,1;30-46. ISSN 1758-1923.

Callihan EB, Gao D, Jindal S, et.al. Postpartum diagnosis demonstrates a high risk for metastasis and merits an expanded definition of pregnancy-associated breast cancer. Breast Cancer REsearch and Treatment. 2013 Feb 22 PMID: 2340224

Rosenberg SM, Tamimi RM, Gelber, S, et al. Body Image in recently diagnosed young women with early breast cancer, Psychooncology. 2012 Nov 7

Jambal P, BAdtke MM, Harell JC, et. al. Estrogen switches pure mucinous breast cancer to invasive lobular carcinoma with mucinous features. Breast Cancer Res Treat, 2012, December 19

Pregnancy-associated breast cancer: an entity needing refinement of the definition. Borges VF, Schedin PJ.Cancer. 2012 Jul 1;118(13):3226-8. doi: 10.1002/cncr.26643. Epub 2011 Nov 15. PMID:22086839[PubMed - indexed for MEDLINE]

Influence of human immune cells on cancer: studies at the University of Colorado. Bruno TC, French JD, Jordan KR, Ramirez O, Sippel TR, Borges VF, Haugen BR, McCarter MD, Waziri A, Slansky JE.Immunol Res. 2013 Mar;55(1-3):22-33. doi: 10.1007/s12026-012-8346-yPMID:22941561

21. Jordan KR, Amaria RN, Ramirez O, Callihan EB, Gao D, Borakove M, Manthey E, Borges VF, McCarter MD. Myeloid-derived suppressor cells are associated with disease progression and decreased overall survival in advanced-stage melanoma patients. Cancer Immunol Immunother. 2013 Sep 27. [Epub ahead of print] PMID:24072401

1. Callihan EB, Gao D, Jindal S, Lyons TR, Manthey E, Edgerton S, Urquhart A, Schedin P, Borges VF. Postpartum diagnosis demonstrates a high risk for metastasis and merits an expanded definition of pregnancy-associated breast cancer. Breast Cancer Res Treat. 2013 2013 Apr;138(2):549-59. Epub Feb 22. PMID:23430224

19. Rosenberg SM, Tamimi RM, Gelber S, Ruddy KJ, Kereakoglow S, Borges VF, Come SE, Schapira L, Winer EP, Partridge AH. Body image in recently diagnosed young women with early breast cancer. Psychooncology. 2013 Aug;22(8):1849-55. doi: 10.1002/pon.3221. Epub 2012 Nov 7. PMID: 23132765

20. Harvell DM, Kim J, O'Brien J, Tan AC, Borges VF, Schedin P, Jacobsen BM, Horwitz KB. Genomic Signatures of Pregnancy-Associated Breast Cancer Epithelia and Stroma and their Regulation by Estrogens and Progesterone. Horm Cancer. 2013 Jun;4(3):140-53. doi: 10.1007/s12672-013-0136-z. Epub 2013 Mar 12 PMID:23479404

33. Julie R Palmer, Emma Viscidi, Melissa A Troester, Chi-Chen Hong, Pepper Schedin, Traci N Bethea, Elisa V Bandera, Virginia Borges, Craig McKinnon, Christopher A Haiman, Kathryn Lunetta, Laurence N Kolonel, Lynn Rosenberg, Andrew F Olshan, Christine B Ambrosone: Parity, Lactation, and Breast Cancer Subtypes in African American Women: Results from the AMBER Consortium.. Journal of the National Cancer Institute. 2014 Sep 15;106(10). pii: dju237. doi: 10.1093/jnci/dju237. Print 2014 Oct. PMID: 25224496

Holly A. Martinson, Sonali Jindal, Clarissa Durand-Rougely, Virginia F. Borges, Pepper Schedin: Wound healing-like immune program facilitates postpartum mammary gland involution and tumor progression. International Journal of Cancer 2014 Sep 4. doi: 10.1002/ijc.29181. [Epub ahead of print] PMID: 25187059

Traci R Lyons, Virginia F Borges, Courtney B Betts, Qiuchen Guo, Puja Kapoor, Holly A Martinson, Sonali Jindal, Pepper Schedin: Cyclooxygenase-2-dependent lymphangiogenesis promotes nodal metastasis of postpartum breast cancer.. The Journal of clinical investigation. 2014 Sep 2;124(9):3901-12. doi: 10.1172/JCI73777. Epub 2014 Aug 18.PMID: 25133426

Shoshana M Rosenberg, Rulla M Tamimi, Shari Gelber, Kathryn J Ruddy, Sharon L Bober, Sandra Kereakoglow, Virginia F Borges, Steven E Come, Lidia Schapira, Ann H Partridge: Treatment-related amenorrhea and sexual functioning in young breast cancer survivors.. Cancer 2014 Aug 1;120(15):2264-71. doi: 10.1002/cncr.28738. Epub 2014 May 28

Jaime Fornetti, Holly A Martinson, Courtney B Betts, Traci R Lyons, Sonali Jindal, Qiuchen Guo, Lisa M Coussens, Virginia F Borges, Pepper Schedin: Mammary Gland Involution as an Immunotherapeutic Target for Postpartum Breast Cancer. Journal of Mammary Gland Biology and Neoplasia 06/2014

Sonali Jindal, Dexiang Gao, Pat Bell, Grethe Albrektsen, Susan M Edgerton, Christine B Ambrosone, Ann D Thor, Virginia F Borges, Pepper Schedin: Postpartum breast involution reveals regression of secretory lobules mediated by tissue-remodeling.. Breast cancer research 2014 Mar 28;16(2):R31. doi: 10.1186/bcr3633.PMID: 24678808

Julie A Carlson, Zohra Nooruddin, Chad Rusthoven, Anthony Elias, Virginia F Borges, Jennifer R Diamond, Brian Kavanagh, Peter Kabos: Trastuzumab emtansine and stereotactic radiosurgery: an unexpected increase in clinically significant brain edema.. Neuro-Oncology 02/2014

17. Jambal P, Badtke MM, Harrell JC, Borges VF, Post MD, Sollender GE, Spillman MA, Horwitz KB, Jacobsen BM. Estrogen switches pure mucinous breast cancer to invasive lobular carcinoma with mucinous features. Breast Cancer Res Treat Breast Cancer Res Treat. 2013 Jan;137(2):431-48. doi: 10.1007/s10549-012-2377-x. Epub 2012 Dec 18. PMID: 23247610

Kathryn J Ruddy, Shari I Gelber, Rulla M Tamimi, Elizabeth S Ginsburg, Lidia Schapira, Steven E Come, Virginia F Borges, Meghan E Meyer, Ann H Partridge: Prospective Study of Fertility Concerns and Preservation Strategies in Young Women With Breast Cancer.. Journal of Clinical Oncology 2014 Apr 10;32(11):1151-6. doi: 10.1200/JCO.2013.52.8877. Epub 2014 Feb 24.PMID: 24567428

Fisher CM, Klein CE, Kondapalli LA, Elias AD, Borges VF. Management of young breast cancer patients with de novo genetic mutations. Oncology (Williston Park). 2014 Oct;28(10). pii: 201947. PMID: 25323616

17. Bruno TC, French JD, Jordan KR, Ramirez O, Sippel TR, Borges VF, Haugen BR, McCarter MD, Waziri A, Slansky JE. Influence of human immune cells on cancer: studies at the University of Colorado. Immunol Res. 2013 Mar;55(1-3):22-33. doi: 10.1007/s12026-012-8346-y. PMID: 22941561

18. Martinson H, Lyons TS, Giles ED, Borges VF, Schedin P. Developmental windows of breast cancer risk provide opportunities for targeted chemoprevention. Experimental Cell Research 2013 July 319, Issue 11:1 1671–1678 doi: 10.1016/j.yexcr.2013.04.018. PMID: 23664839

Borges VF. Management of the Patient with Post-partum Breast Cancer. Oncology 2014 Sept; 28(9) http://www.cancernetwork.com/journals/oncology/issue/vol-28-no-9

Sartorius CA, Hanna CT, Gril B, Cruz H, Serkova NJ, Huber KM, Kabos P, Schedin TB, Borges VF, Steeg PS, Cittelly DM. Estrogen promotes the brain metastatic colonization of triple negative breast cancer cells via an astrocyte-mediated paracrine mechanism. Oncogene. 2015 Sep 28. [Epub ahead of print] PubMed PMID: 26411365

Jasem J, Altoos B, Fisher CM, Elias AD, Kounalakis N, Borges VF, Kabos P. Multiple Hepatic Lesions in a Patient With a History of DCIS. Oncology (Williston Park). 2015 Sep;29(9):669-70, 678-9. PubMed PMID: 26384804

Russell TD, Jindal S, Agunbiade S, Gao D, Troxell M, Borges VF, Schedin P. Myoepithelial cell differentiation markers in ductal carcinoma in situ progression. Am J Pathol. 2015 Nov;185(11):3076-89. PubMed PMID: 26343330

Fornetti J, Flanders KC, Henson PM, Tan AC, Borges VF, Schedin P. Mammary epithelial cell phagocytosis downstream of TGF-ß3 is characterized by adherens junction reorganization. Cell Death Differ. 2016 Feb;23(2):185-96. PubMed PMID: 26113040

Overholser L, Shagisultanova E, Rabinovitch RA, Kounalakis N, Diamond J, Finlayson CA, Fisher CM, Kabos P, Elias AD, Borges VF, Mayordomo J. Breast Cancer Following Radiation for Hodgkin Lymphoma: Clinical Scenarios and Risk-Reducing Strategies. Oncology (Williston Park). 2016 Dec 15;30(12). PubMed PMID: 27987198

Collins LC, Gelber S, Marotti JD, White S, Ruddy K, Brachtel EF, Schapira L, Come SE, Borges VF, Schedin P, Warner E, Wensley T, Tamimi RM, Winer EP, Partridge AH. Molecular Phenotype of Breast Cancer According to Time Since Last Pregnancy in a Large Cohort of Young Women. Oncologist. 2015 Jul;20(7):713-8. PubMed PMID: 26025931

Goddard ET, Hill RC, Nemkov T, D'Alessandro A, Hansen KC, Maller O, Mongoue-Tchokote S, Mori M, Partridge AH, Borges VF, Schedin P. The Rodent Liver Undergoes Weaning-Induced Involution and Supports Breast Cancer Metastasis. Cancer Discov. 2017 Feb;7(2):177-187. PubMed PMID: 27974414

Borges VF, Elder AM, Lyons TR. Deciphering Pro-Lymphangiogenic Programs during Mammary Involution and Postpartum Breast Cancer. Front Oncol. 2016 Nov 2;6:227. PubMed PMID: 27853703

Rosenberg SM, Sepucha K, Ruddy KJ, Tamimi RM, Gelber S, Meyer ME, Schapira L, Come SE, Borges VF, Golshan M, Winer EP, Partridge AH. Local Therapy Decision-Making and Contralateral Prophylactic Mastectomy in Young Women with Early-Stage Breast Cancer. Ann Surg Oncol. 2015 Nov;22(12):3809-15. PubMed PMID: 25930247

Goddard ET, Hill RC, Barrett A, Betts C, Guo Q, Maller O, Borges VF, Hansen KC, Schedin P. Quantitative extracellular matrix proteomics to study mammary and liver tissue microenvironments. Int J Biochem Cell Biol. 2016 Dec;81(Pt A):223-232. PubMed PMID: 27771439

Martinson HA, Jindal S, Durand-Rougely C, Borges VF, Schedin P. Wound healing-like immune program facilitates postpartum mammary gland involution and tumor progression. Int J Cancer. 2015 Apr 15;136(8):1803-13. PubMed PMID: 25187059

Brown RJ, Murphy CD, Lisella GH, Libby AL, Njiaju UO, Rabinovitch RA, Borges VF. A 40-Year-Old Woman With a New Triple-Negative Breast Mass, Shown on Biopsy to Be Metaplastic Carcinoma. Oncology (Williston Park). 2016 Jul;30(7):628-31, 652. PubMed PMID: 27432366

Munson DJ, Egelston CA, Chiotti KE, Parra ZE, Bruno TC, Moore BL, Nakano TA, Simons DL, Jimenez G, Yim JH, Rozanov DV, Falta MT, Fontenot AP, Reynolds PR, Leach SM, Borges VF, Kappler JW, Spellman PT, Lee PP, Slansky JE. Identification of shared TCR sequences from T cells in human breast cancer using emulsion RT-PCR. Proc Natl Acad Sci U S A. 2016 Jul 19;113(29):8272-7. PubMed PMID: 27307436

Jasem J, Amini A, Rabinovitch R, Borges VF, Elias A, Fisher CM, Kabos P. 21-Gene Recurrence Score Assay As a Predictor of Adjuvant Chemotherapy Administration for Early-Stage Breast Cancer: An Analysis of Use, Therapeutic Implications, and Disparity Profile. J Clin Oncol. 2016 Jun 10;34(17):1995-2002. PubMed PMID: 27001563

Rosenberg SM, Ruddy KJ, Tamimi RM, Gelber S, Schapira L, Come S, Borges VF, Larsen B, Garber JE, Partridge AH. BRCA1 and BRCA2 Mutation Testing in Young Women With Breast Cancer. JAMA Oncol. 2016 Jun 1;2(6):730-6. PubMed PMID: 26867710

Sartorius CA, Hanna CT, Gril B, Cruz H, Serkova NJ, Huber KM, Kabos P, Schedin TB, Borges VF, Steeg PS, Cittelly DM. Estrogen promotes the brain metastatic colonization of triple negative breast cancer cells via an astrocyte-mediated paracrine mechanism. Oncogene. 2016 Jun 2;35(22):2881-92. PubMed PMID: 26411365

Fornetti J, Flanders KC, Henson PM, Tan AC, Borges VF, Schedin P. Mammary epithelial cell phagocytosis downstream of TGF-ß3 is characterized by adherens junction reorganization. Cell Death Differ. 2016 Feb;23(2):185-96. PubMed PMID: 26113040

Coccia PF, Pappo AS, Beaupin L, Borges VF, Borinstein SC, Chugh R, Dinner S, Folbrecht J, Frazier AL, Goldsby R, Gubin A, Hayashi R, Huang MS, Link MP, Livingston JA, Matloub Y, Millard F, Oeffinger KC, Puccetti D, Reed D, Robinson S, Rosenberg AR, Sanft T, Spraker-Perlman HL, von Mehren M, Wechsler DS, Whelan KF, Yeager N, Gurski LA, Shead DA. Adolescent and Young Adult Oncology, Version 2.2018, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2018 Jan;16(1):66-97. PubMed PMID: 29295883

Contreras-Zárate MJ, Ormond DR, Gillen AE, Hanna C, Day NL, Serkova NJ, Jacobsen BM, Edgerton SM, Thor AD, Borges VF, Lillehei KO, Graner MW, Kabos P, Cittelly DM. Development of Novel Patient-Derived Xenografts from Breast Cancer Brain Metastases. Front Oncol. 2017;7:252. PubMed PMID: 29164052

Goddard ET, Bassale S, Schedin T, Jindal S, Johnston J, Cabral E, Latour E, Lyons TR, Mori M, Schedin PJ, Borges VF. Association Between Postpartum Breast Cancer Diagnosis and Metastasis and the Clinical Features Underlying Risk. JAMA Netw Open. 2019 Jan 4;2(1):e186997. PubMed PMID: 30646210

Harris EER, De Los Santos J, Borges VF, Grobmyer SR. Innovations in Personalized and Targeted Therapies for Breast Cancer. Int J Breast Cancer. 2018;2018:5409846. PubMed PMID: 30538865

Chollet-Hinton L, Olshan AF, Nichols HB, Anders CK, Lund JL, Allott EH, Bethea TN, Hong CC, Cohen SM, Khoury T, Zirpoli GR, Borges VF, Rosenberg LA, Bandera EV, Ambrosone CB, Palmer JR, Troester MA. Biology and Etiology of Young-Onset Breast Cancers among Premenopausal African American Women: Results from the AMBER Consortium. Cancer Epidemiol Biomarkers Prev. 2017 Dec;26(12):1722-1729. PubMed PMID: 28903991

Pennock ND, Martinson HA, Guo Q, Betts CB, Jindal S, Tsujikawa T, Coussens LM, Borges VF, Schedin P. Ibuprofen supports macrophage differentiation, T cell recruitment, and tumor suppression in a model of postpartum breast cancer. J Immunother Cancer. 2018 Oct 1;6(1):98. PubMed PMID: 30285905

Elder AM, Tamburini BAJ, Crump LS, Black SA, Wessells VM, Schedin PJ, Borges VF, Lyons TR. Semaphorin 7A Promotes Macrophage-Mediated Lymphatic Remodeling during Postpartum Mammary Gland Involution and in Breast Cancer. Cancer Res. 2018 Nov 15;78(22):6473-6485. PubMed PMID: 30254150

Brown RJ, Sams S, Wolverton DE, Chong T, Borges VF, Rabinovitch RA, Murphy CD. Don't Be Fooled by DCIS. Oncology (Williston Park). 2017 Jul 15;31(7):549-51, 560-1. PubMed PMID: 28712099

Jasem J, Fisher CM, Amini A, Shagisultanova E, Rabinovitch R, Borges VF, Elias A, Kabos P. The 21-Gene Recurrence Score Assay for Node-Positive, Early-Stage Breast Cancer and Impact of RxPONDER Trial on Chemotherapy Decision-Making: Have Clinicians Already Decided?. J Natl Compr Canc Netw. 2017 Apr;15(4):494-503. PubMed PMID: 28404760

Greene LI, Bruno TC, Christenson JL, D'Alessandro A, Culp-Hill R, Torkko K, Borges VF, Slansky JE, Richer JK. A Role for Tryptophan-2,3-dioxygenase in CD8 T-cell Suppression and Evidence of Tryptophan Catabolism in Breast Cancer Patient Plasma. Mol Cancer Res. 2019 Jan;17(1):131-139. PubMed PMID: 30143553

Tobin RP, Jordan KR, Robinson WA, Davis D, Borges VF, Gonzalez R, Lewis KD, McCarter MD. Targeting myeloid-derived suppressor cells using all-trans retinoic acid in melanoma patients treated with Ipilimumab. Int Immunopharmacol. 2018 Oct;63:282-291. PubMed PMID: 30121453

Diamond JR, Eckhardt SG, Pitts TM, van Bokhoven A, Aisner D, Gustafson DL, Capasso A, Sams S, Kabos P, Zolman K, Colvin T, Elias AD, Storniolo AM, Schneider BP, Gao D, Tentler JJ, Borges VF, Miller KD. A phase II clinical trial of the Aurora and angiogenic kinase inhibitor ENMD-2076 for previously treated, advanced, or metastatic triple-negative breast cancer. Breast Cancer Res. 2018 Aug 2;20(1):82. PubMed PMID: 30071865

Schedin TB, Borges VF, Shagisultanova E. Overcoming Therapeutic Resistance of Triple Positive Breast Cancer with CDK4/6 Inhibition. Int J Breast Cancer. 2018;2018:7835095. PubMed PMID: 30018827

Borges VF, Ferrario C, Aucoin N, Falkson C, Khan Q, Krop I, Welch S, Conlin A, Chaves J, Bedard PL, Chamberlain M, Gray T, Vo A, Hamilton E. Tucatinib Combined With Ado-Trastuzumab Emtansine in Advanced ERBB2/HER2-Positive Metastatic Breast Cancer: A Phase 1b Clinical Trial. JAMA Oncol. 2018 Sep 1;4(9):1214-1220. PubMed PMID: 29955792

Stoen E, Kabos P, Borden KC, Brown RJ, Borges VF, Diamond JR. A 35-Year-Old Woman With a Change in HER2 Expression Following Neoadjuvant Chemotherapy for Invasive Breast Cancer. Oncology (Williston Park). 2018 Jun;32(6):298-302. PubMed PMID: 29940061

Jordan KR, Kapoor P, Spongberg E, Tobin RP, Gao D, Borges VF, McCarter MD. Immunosuppressive myeloid-derived suppressor cells are increased in splenocytes from cancer patients. Cancer Immunol Immunother. 2017 Apr;66(4):503-513. PubMed PMID: 28108766

Betts CB, Pennock ND, Caruso BP, Ruffell B, Borges VF, Schedin P. Mucosal Immunity in the Female Murine Mammary Gland. J Immunol. 2018 Jul 15;201(2):734-746. PubMed PMID: 29884705

Moulder SL, Borges VF, Baetz T, Mcspadden T, Fernetich G, Murthy RK, Chavira R, Guthrie K, Barrett E, Chia SK. Phase I Study of ONT-380, a HER2 Inhibitor, in Patients with HER2( )-Advanced Solid Tumors, with an Expansion Cohort in HER2( ) Metastatic Breast Cancer (MBC). Clin Cancer Res. 2017 Jul 15;23(14):3529-3536. PubMed PMID: 28053022

Murthy R, Borges VF, Conlin A, Chaves J, Chamberlain M, Gray T, Vo A, Hamilton E. Tucatinib with capecitabine and trastuzumab in advanced HER2-positive metastatic breast cancer with and without brain metastases: a non-randomised, open-label, phase 1b study. Lancet Oncol. 2018 Jul;19(7):880-888. PubMed PMID: 29804905

Coccia PF, Pappo AS, Beaupin L, Borges VF, Borinstein SC, Chugh R, Dinner S, Folbrecht J, Frazier AL, Goldsby R, Gubin A, Hayashi R, Huang MS, Link MP, Livingston JA, Matloub Y, Millard F, Oeffinger KC, Puccetti D, Reed D, Robinson S, Rosenberg AR, Sanft T, Spraker-Perlman HL, von Mehren M, Wechsler DS, Whelan KF, Yeager N, Gurski LA, Shead DA. Adolescent and Young Adult Oncology, Version 2.2018, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2018 Jan;16(1):66-97. PubMed PMID: 29295883

Goddard ET, Hill RC, Nemkov T, D'Alessandro A, Hansen KC, Maller O, Mongoue-Tchokote S, Mori M, Partridge AH, Borges VF, Schedin P. The Rodent Liver Undergoes Weaning-Induced Involution and Supports Breast Cancer Metastasis. Cancer Discov. 2017 Feb;7(2):177-187. PubMed PMID: 27974414

Cox-Martin E, Anderson-Mellies A, Borges V, Bradley C. Chronic pain, health-related quality of life, and employment in working-age cancer survivors. J Cancer Surviv. 2019 Dec 11. [Epub ahead of print] PubMed PMID: 31828603

Murthy RK, Loi S, Okines A, Paplomata E, Hamilton E, Hurvitz SA, Lin NU, Borges V, Abramson V, Anders C, Bedard PL, Oliveira M, Jakobsen E, Bachelot T, Shachar SS, Müller V, Braga S, Duhoux FP, Greil R, Cameron D, Carey LA, Curigliano G, Gelmon K, Hortobagyi G, Krop I, Loibl S, Pegram M, Slamon D, Palanca-Wessels MC, Walker L, Feng W, Winer EP. Tucatinib, Trastuzumab, and Capecitabine for HER2-Positive Metastatic Breast Cancer. N Engl J Med. 2019 Dec 11. [Epub ahead of print] PubMed PMID: 31825569

Fehrenbacher L, Cecchini RS, Geyer CE Jr, Rastogi P, Costantino JP, Atkins JN, Crown JP, Polikoff J, Boileau JF, Provencher L, Stokoe C, Moore TD, Robidoux A, Flynn PJ, Borges VF, Albain KS, Swain SM, Paik S, Mamounas EP, Wolmark N. NSABP B-47/NRG Oncology Phase III Randomized Trial Comparing Adjuvant Chemotherapy With or Without Trastuzumab in High-Risk Invasive Breast Cancer Negative for HER2 by FISH and With IHC 1 or 2. J Clin Oncol. 2019 Dec 10;:JCO1901455. [Epub ahead of print] PubMed PMID: 31821109

Poorvu PD, Gelber SI, Rosenberg SM, Ruddy KJ, Tamimi RM, Collins LC, Peppercorn J, Schapira L, Borges VF, Come SE, Warner E, Jakubowski DM, Russell C, Winer EP, Partridge AH. Prognostic Impact of the 21-Gene Recurrence Score Assay Among Young Women With Node-Negative and Node-Positive ER-Positive/HER2-Negative Breast Cancer. J Clin Oncol. 2019 Dec 6;:JCO1901959. [Epub ahead of print] PubMed PMID: 31809240

Tobin RP, Jordan KR, Kapoor P, Spongberg E, Davis D, Vorwald VM, Couts KL, Gao D, Smith DE, Borgers JSW, Robinson S, Amato C, Gonzalez R, Lewis KD, Robinson WA, Borges VF, McCarter MD. IL-6 and IL-8 Are Linked With Myeloid-Derived Suppressor Cell Accumulation and Correlate With Poor Clinical Outcomes in Melanoma Patients. Front Oncol. 2019;9:1223. PubMed PMID: 31781510

Lee GE, Rosenberg SM, Mayer EL, Borges V, Meyer ME, Schapira L, Come SE, Partridge AH. Contemporary management of breast cancer during pregnancy and subsequent lactation in a multicenter cohort of young women with breast cancer. Breast J. 2019 Nov;25(6):1104-1110. PubMed PMID: 31318125

Korobeynikov V, Borakove M, Feng Y, Wuest WM, Koval AB, Nikonova AS, Serebriiskii I, Chernoff J, Borges VF, Golemis EA, Shagisultanova E. Combined inhibition of Aurora A and p21-activated kinase 1 as a new treatment strategy in breast cancer. Breast Cancer Res Treat. 2019 Sep;177(2):369-382. PubMed PMID: 31254157

Tamburini BAJ, Elder AM, Finlon JM, Winter AB, Wessells VM, Borges VF, Lyons TR. PD-1 Blockade During Post-partum Involution Reactivates the Anti-tumor Response and Reduces Lymphatic Vessel Density. Front Immunol. 2019;10:1313. PubMed PMID: 31244852

Rosenberg SM, Vaz-Luis I, Gong J, Rajagopal PS, Ruddy KJ, Tamimi RM, Schapira L, Come S, Borges V, de Moor JS, Partridge AH. Employment trends in young women following a breast cancer diagnosis. Breast Cancer Res Treat. 2019 Aug;177(1):207-214. PubMed PMID: 31147983

Wassermann J, Gelber SI, Rosenberg SM, Ruddy KJ, Tamimi RM, Schapira L, Borges VF, Come SE, Meyer ME, Partridge AH. Nonadherent behaviors among young women on adjuvant endocrine therapy for breast cancer. Cancer. 2019 Sep 15;125(18):3266-3274. PubMed PMID: 31120571

Rath M, Li Q, Li H, Lindström S, Miron A, Miron P, Dowton AE, Meyer ME, Larson BG, Pomerantz M, Seo JH, Collins LC, Vardeh H, Brachtel E, Come SE, Borges V, Schapira L, Tamimi RM, Partridge AH, Freedman M, Ruddy KJ. Evaluation of significant genome-wide association studies risk - SNPs in young breast cancer patients. PLoS One. 2019;14(5):e0216997. PubMed PMID: 31125336

von Hippel C, Rosenberg SM, Austin SB, Sprunck-Harrild K, Ruddy KJ, Schapira L, Come S, Borges VF, Partridge AH. Identifying distinct trajectories of change in young breast cancer survivors' sexual functioning. Psychooncology. 2019 May;28(5):1033-1040. PubMed PMID: 30817075

Contreras-Zárate MJ, Day NL, Ormond DR, Borges VF, Tobet S, Gril B, Steeg PS, Cittelly DM. Estradiol induces BDNF/TrkB signaling in triple-negative breast cancer to promote brain metastases. Oncogene. 2019 Jun;38(24):4685-4699. PubMed PMID: 30796353

Goddard ET, Bassale S, Schedin T, Jindal S, Johnston J, Cabral E, Latour E, Lyons TR, Mori M, Schedin PJ, Borges VF. Association Between Postpartum Breast Cancer Diagnosis and Metastasis and the Clinical Features Underlying Risk. JAMA Netw Open. 2019 Jan 4;2(1):e186997. PubMed PMID: 30646210

Greene LI, Bruno TC, Christenson JL, D'Alessandro A, Culp-Hill R, Torkko K, Borges VF, Slansky JE, Richer JK. A Role for Tryptophan-2,3-dioxygenase in CD8 T-cell Suppression and Evidence of Tryptophan Catabolism in Breast Cancer Patient Plasma. Mol Cancer Res. 2019 Jan;17(1):131-139. PubMed PMID: 30143553

Sakamoto MR, Eguchi M, Azelby CM, Diamond JR, Fisher CM, Borges VF, Bradley CJ, Kabos P. New Persistent Opioid and Benzodiazepine Use After Curative-Intent Treatment in Patients With Breast Cancer. J Natl Compr Canc Netw. 2021 Jan 6;19(1):29-38. PubMed PMID: 33406490

Kim HJ, Dominici L, Rosenberg SM, Zheng Y, Pak LM, Poorvu PD, Ruddy KJ, Tamimi R, Schapira L, Come SE, Peppercorn J, Borges VF, Warner E, Vardeh H, Collins LC, Gaither R, King TA, Partridge AH. Surgical Treatment after Neoadjuvant Systemic Therapy in Young Women with Breast Cancer: Results from a Prospective Cohort Study. Ann Surg. 2020 Dec 23;Publish Ahead of Print. [Epub ahead of print] PubMed PMID: 33378304

Jindal S, Pennock ND, Klug A, Narasimhan J, Calhoun A, Roberts MR, Tamimi RM, Eliassen AH, Weinmann S, Borges VF, Schedin P. S-nitrosylated and non-nitrosylated COX2 have differential expression and distinct subcellular localization in normal and breast cancer tissue. NPJ Breast Cancer. 2020 Nov 24;6(1):62. PubMed PMID: 33298921

Poorvu PD, Gelber SI, Zheng Y, Ruddy KJ, Tamimi RM, Peppercorn J, Schapira L, Borges VF, Come SE, Lambertini M, Rosenberg SM, Partridge AH. Pregnancy after breast cancer: Results from a prospective cohort of young women with breast cancer. Cancer. 2020 Dec 1. [Epub ahead of print] PubMed PMID: 33259061

Pak LM, Gaither R, Rosenberg SM, Ruddy KJ, Tamimi RM, Peppercorn J, Schapira L, Borges VF, Come SE, Warner E, Snow C, Collins LC, King TA, Partridge AH. Tumor phenotype and concordance in synchronous bilateral breast cancer in young women. Breast Cancer Res Treat. 2020 Nov 26. [Epub ahead of print] PubMed PMID: 33242164

Jordan KR, Hall JK, Schedin T, Borakove M, Xian JJ, Dzieciatkowska M, Lyons TR, Schedin P, Hansen KC, Borges VF. Extracellular vesicles from young women's breast cancer patients drive increased invasion of non-malignant cells via the Focal Adhesion Kinase pathway: a proteomic approach. Breast Cancer Res. 2020 Nov 23;22(1):128. PubMed PMID: 33225939

Sella T, Gelber SI, Poorvu PD, Kim HJ, Dominici L, Guzman-Arocho YD, Collins L, Ruddy KJ, Tamimi RM, Peppercorn JM, Schapira L, Borges VF, Come SE, Warner E, Snow C, Jakubowski DM, Russell CA, Winer EP, Rosenberg SM, Partridge AH. Response to neoadjuvant chemotherapy and the 21-gene Breast Recurrence Score test in young women with estrogen receptor-positive early breast cancer. Breast Cancer Res Treat. 2020 Nov 4. [Epub ahead of print] PubMed PMID: 33150547

Borges VF, Hu J, Young C, Maggard J, Parris HJ, Gao D, Lyons TR. Semaphorin 7a is a biomarker for recurrence in postpartum breast cancer. NPJ Breast Cancer. 2020;6:56. PubMed PMID: 33088913

Jindal S, Narasimhan J, Borges VF, Schedin P. Characterization of weaning-induced breast involution in women: implications for young women's breast cancer. NPJ Breast Cancer. 2020;6:55. PubMed PMID: 33083533

Weiss JA, Nicklawsky A, Kagihara JA, Gao D, Fisher C, Elias A, Borges VF, Kabos P, Davis SL, Leong S, Eckhardt SG, Diamond JR. Clinical outcomes of breast cancer patients treated in phase I clinical trials at University of Colorado Cancer Center. Cancer Med. 2020 Dec;9(23):8801-8808. PubMed PMID: 33063469

Borstelmann NA, Rosenberg S, Gelber S, Zheng Y, Meyer M, Ruddy KJ, Schapira L, Come S, Borges V, Cadet T, Maramaldi P, Partridge AH. Partners of young breast cancer survivors: a cross-sectional evaluation of psychosocial concerns, coping, and mental health. J Psychosoc Oncol. 2020 Nov-Dec;38(6):670-686. PubMed PMID: 33000705

Marsh S, Borges VF, Coons HL, Afghahi A. Sexual health after a breast cancer diagnosis in young women: clinical implications for patients and providers. Breast Cancer Res Treat. 2020 Dec;184(3):655-663. PubMed PMID: 32968951

Rosenberg SM, Dominici LS, Gelber S, Poorvu PD, Ruddy KJ, Wong JS, Tamimi RM, Schapira L, Come S, Peppercorn JM, Borges VF, Partridge AH. Association of Breast Cancer Surgery With Quality of Life and Psychosocial Well-being in Young Breast Cancer Survivors. JAMA Surg. 2020 Nov 1;155(11):1035-1042. PubMed PMID: 32936216

Lin NU, Borges V, Anders C, Murthy RK, Paplomata E, Hamilton E, Hurvitz S, Loi S, Okines A, Abramson V, Bedard PL, Oliveira M, Mueller V, Zelnak A, DiGiovanna MP, Bachelot T, Chien AJ, O'Regan R, Wardley A, Conlin A, Cameron D, Carey L, Curigliano G, Gelmon K, Loibl S, Mayor J, McGoldrick S, An X, Winer EP. Intracranial Efficacy and Survival With Tucatinib Plus Trastuzumab and Capecitabine for Previously Treated HER2-Positive Breast Cancer With Brain Metastases in the HER2CLIMB Trial. J Clin Oncol. 2020 Aug 10;38(23):2610-2619. PubMed PMID: 32468955

Tung N, Arun B, Hacker MR, Hofstatter E, Toppmeyer DL, Isakoff SJ, Borges V, Legare RD, Isaacs C, Wolff AC, Marcom PK, Mayer EL, Lange PB, Goss AJ, Jenkins C, Krop IE, Winer EP, Schnitt SJ, Garber JE. TBCRC 031: Randomized Phase II Study of Neoadjuvant Cisplatin Versus Doxorubicin-Cyclophosphamide in Germline BRCA Carriers With HER2-Negative Breast Cancer (the INFORM trial). J Clin Oncol. 2020 May 10;38(14):1539-1548. PubMed PMID: 32097092

Borges VF, Lyons TR, Germain D, Schedin P. Postpartum Involution and Cancer: An Opportunity for Targeted Breast Cancer Prevention and Treatments?. Cancer Res. 2020 May 1;80(9):1790-1798. PubMed PMID: 32075799

Tarullo SE, Hill RC, Hansen KC, Behbod F, Borges VF, Nelson AC, Lyons TR. Postpartum breast cancer progression is driven by semaphorin 7a-mediated invasion and survival. Oncogene. 2020 Mar;39(13):2772-2785. PubMed PMID: 32020054

Cox-Martin E, Anderson-Mellies A, Borges V, Bradley C. Chronic pain, health-related quality of life, and employment in working-age cancer survivors. J Cancer Surviv. 2020 Apr;14(2):179-187. PubMed PMID: 31828603

Murthy RK, Loi S, Okines A, Paplomata E, Hamilton E, Hurvitz SA, Lin NU, Borges V, Abramson V, Anders C, Bedard PL, Oliveira M, Jakobsen E, Bachelot T, Shachar SS, Müller V, Braga S, Duhoux FP, Greil R, Cameron D, Carey LA, Curigliano G, Gelmon K, Hortobagyi G, Krop I, Loibl S, Pegram M, Slamon D, Palanca-Wessels MC, Walker L, Feng W, Winer EP. Tucatinib, Trastuzumab, and Capecitabine for HER2-Positive Metastatic Breast Cancer. N Engl J Med. 2020 Feb 13;382(7):597-609. PubMed PMID: 31825569

Fehrenbacher L, Cecchini RS, Geyer CE Jr, Rastogi P, Costantino JP, Atkins JN, Crown JP, Polikoff J, Boileau JF, Provencher L, Stokoe C, Moore TD, Robidoux A, Flynn PJ, Borges VF, Albain KS, Swain SM, Paik S, Mamounas EP, Wolmark N. NSABP B-47/NRG Oncology Phase III Randomized Trial Comparing Adjuvant Chemotherapy With or Without Trastuzumab in High-Risk Invasive Breast Cancer Negative for HER2 by FISH and With IHC 1 or 2. J Clin Oncol. 2020 Feb 10;38(5):444-453. PubMed PMID: 31821109

Poorvu PD, Gelber SI, Rosenberg SM, Ruddy KJ, Tamimi RM, Collins LC, Peppercorn J, Schapira L, Borges VF, Come SE, Warner E, Jakubowski DM, Russell C, Winer EP, Partridge AH. Prognostic Impact of the 21-Gene Recurrence Score Assay Among Young Women With Node-Negative and Node-Positive ER-Positive/HER2-Negative Breast Cancer. J Clin Oncol. 2020 Mar 1;38(7):725-733. PubMed PMID: 31809240

Curigliano G, Mueller V, Borges V, Hamilton E, Hurvitz S, Loi S, Murthy R, Okines A, Paplomata E, Cameron D, Carey LA, Gelmon K, Hortobagyi GN, Krop I, Loibl S, Pegram M, Slamon D, Ramos J, Feng W, Winer E. Tucatinib vs Placebo Added to Trastuzumab and Capecitabine for Patients with Pretreated HER2 Metastatic Breast Cancer with and without Brain Metastases (HER2CLIMB): Final Overall Survival Analysis. Ann Oncol. 2021 Dec 22. [Epub ahead of print] PubMed PMID: 34954044

Borges VF. The Expanded Role of Ovarian Suppression for Young Women's Breast Cancer: An Era of Patient-Tailored Decision Making. J Natl Cancer Inst. 2021 Nov 25. [Epub ahead of print] PubMed PMID: 34850044

Jindal S, Pennock ND, Sun D, Horton W, Ozaki MK, Narasimhan J, Bartlett AQ, Weinmann S, Goss PE, Borges VF, Xia Z, Schedin P. Postpartum breast cancer has a distinct molecular profile that predicts poor outcomes. Nat Commun. 2021 Nov 3;12(1):6341. PubMed PMID: 34732713

Shagisultanova E, Crump LS, Borakove M, Hall JK, Rasti AR, Harrison BA, Kabos P, Lyons TR, Borges VF. Triple Targeting of Breast Tumors Driven by Hormonal Receptors and HER2. Mol Cancer Ther. 2022 Jan;21(1):48-57. PubMed PMID: 34728571

Borges VF. Options for Endocrine-Refractory, Hormone Receptor-Positive Breast Cancer: Which Target and When?. J Clin Oncol. 2021 Dec 10;39(35):3890-3896. PubMed PMID: 34709849

O'Sullivan CC, Ballman KV, McCall L, Kommalapati A, Zemla T, Weiss A, Mitchell M, Blinder V, Tung NM, Irvin WJ, Lee M, Goetz MP, Symmans WF, Borges VF, Krop I, Carey LA, Partridge AH. Alliance A011801 (compassHER2 RD): postneoadjuvant T-DM1 tucatinib/placebo in patients with residual HER2-positive invasive breast cancer. Future Oncol. 2021 Dec;17(34):4665-4676. PubMed PMID: 34636255

Dominici L, Hu J, Zheng Y, Kim HJ, King TA, Ruddy KJ, Tamimi RM, Peppercorn J, Schapira L, Borges VF, Come SE, Warner E, Wong JS, Partridge AH, Rosenberg SM. Association of Local Therapy With Quality-of-Life Outcomes in Young Women With Breast Cancer. JAMA Surg. 2021 Oct 1;156(10):e213758. PubMed PMID: 34468718

Partridge AH, Niman SM, Ruggeri M, Peccatori FA, Azim HA Jr, Colleoni M, Saura C, Shimizu C, Sætersdal AB, Kroep JR, Mailliez A, Warner E, Borges VF, Amant F, Gombos A, Kataoka A, Rousset-Jablonski C, Borstnar S, Takei J, Lee JE, Walshe JM, Borrego MR, Moore HC, Saunders C, Cardoso F, Susnjar S, Bjelic-Radisic V, Smith KL, Piccart M, Korde LA, Goldhirsch A, Gelber RD, Pagani O. Who are the women who enrolled in the POSITIVE trial: A global study to support young hormone receptor positive breast cancer survivors desiring pregnancy. Breast. 2021 Oct;59:327-338. PubMed PMID: 34390999

Poorvu PD, Hu J, Zheng Y, Gelber SI, Ruddy KJ, Tamimi RM, Peppercorn JM, Schapira L, Borges VF, Come SE, Warner E, Lambertini M, Rosenberg SM, Partridge AH. Treatment-related amenorrhea in a modern, prospective cohort study of young women with breast cancer. NPJ Breast Cancer. 2021 Jul 27;7(1):99. PubMed PMID: 34315890

Amant F, Lefrère H, Borges VF, Cardonick E, Lambertini M, Loibl S, Peccatori F, Partridge A, Schedin P. The definition of pregnancy-associated breast cancer is outdated and should no longer be used. Lancet Oncol. 2021 Jun;22(6):753-754. PubMed PMID: 34087122

Sella T, Poorvu PD, Ruddy KJ, Gelber SI, Tamimi RM, Peppercorn JM, Schapira L, Borges VF, Come SE, Partridge AH, Rosenberg SM. Impact of fertility concerns on endocrine therapy decisions in young breast cancer survivors. Cancer. 2021 Aug 15;127(16):2888-2894. PubMed PMID: 33886123

Chmura S, Winter KA, Robinson C, Pisansky TM, Borges V, Al-Hallaq H, Matuszak M, Park SS, Yi S, Hasan Y, Bazan J, Wong P, Yoon HA, Horton J, Gan G, Milano MT, Sigurdson ER, Moughan J, Salama JK, White J. Evaluation of Safety of Stereotactic Body Radiotherapy for the Treatment of Patients With Multiple Metastases: Findings From the NRG-BR001 Phase 1 Trial. JAMA Oncol. 2021 Jun 1;7(6):845-852. PubMed PMID: 33885704

Kuijer A, Dominici LS, Rosenberg SM, Hu J, Gelber S, Di Lascio S, Wong JS, Ruddy KJ, Tamimi RM, Schapira L, Borges VF, Come SE, Sprunck-Harrild K, Partridge AH, King TA. Arm Morbidity After Local Therapy for Young Breast Cancer Patients. Ann Surg Oncol. 2021 Oct;28(11):6071-6082. PubMed PMID: 33881656

Schreiber AR, Kagihara JA, Weiss JA, Nicklawsky A, Gao D, Borges VF, Kabos P, Diamond JR. Clinical Outcomes for Patients With Metastatic Breast Cancer Treated With Immunotherapy Agents in Phase I Clinical Trials. Front Oncol. 2021;11:640690. PubMed PMID: 33816286

Lefrère H, Lenaerts L, Borges VF, Schedin P, Neven P, Amant F. Postpartum breast cancer: mechanisms underlying its worse prognosis, treatment implications, and fertility preservation. Int J Gynecol Cancer. 2021 Mar;31(3):412-422. PubMed PMID: 33649008

Stoen E, Kagihara J, Shagisultanova E, Fisher CM, Nicklawsky A, Kabos P, Borges VF, Diamond JR. Real-world evidence from a University Hospital system regarding the uptake of adjuvant pertuzumab and/or neratinib before and after their FDA approval. Breast Cancer Res Treat. 2021 Jun;187(3):883-891. PubMed PMID: 33625615

Sakamoto MR, Eguchi M, Azelby CM, Diamond JR, Fisher CM, Borges VF, Bradley CJ, Kabos P. New Persistent Opioid and Benzodiazepine Use After Curative-Intent Treatment in Patients With Breast Cancer. J Natl Compr Canc Netw. 2021 Jan 6;19(1):29-38. PubMed PMID: 33406490

Pak LM, Gaither R, Rosenberg SM, Ruddy KJ, Tamimi RM, Peppercorn J, Schapira L, Borges VF, Come SE, Warner E, Snow C, Collins LC, King TA, Partridge AH. Tumor phenotype and concordance in synchronous bilateral breast cancer in young women. Breast Cancer Res Treat. 2021 Apr;186(3):815-821. PubMed PMID: 33242164

Sella T, Gelber SI, Poorvu PD, Kim HJ, Dominici L, Guzman-Arocho YD, Collins L, Ruddy KJ, Tamimi RM, Peppercorn JM, Schapira L, Borges VF, Come SE, Warner E, Snow C, Jakubowski DM, Russell CA, Winer EP, Rosenberg SM, Partridge AH. Response to neoadjuvant chemotherapy and the 21-gene Breast Recurrence Score test in young women with estrogen receptor-positive early breast cancer. Breast Cancer Res Treat. 2021 Feb;186(1):157-165. PubMed PMID: 33150547

Curigliano G, Mueller V, Borges V, Hamilton E, Hurvitz S, Loi S, Murthy R, Okines A, Paplomata E, Cameron D, Carey LA, Gelmon K, Hortobagyi GN, Krop I, Loibl S, Pegram M, Slamon D, Ramos J, Feng W, Winer E. Corrigendum to "Tucatinib versus placebo added to trastuzumab and capecitabine for patients with pretreated HER2D metastatic breast cancer with and without brain metastases (HER2CLIMB): final overall survival analysis": [Annals of Oncology 33 (2022) 321-329]. Ann Oncol. 2022 Dec 21. [Epub ahead of print] PubMed PMID: 36564285

Purcell SA, Melanson EL, Afghahi A, Borges VF, Sinelli I, Cornier MA. The effects of resistance exercise on appetite sensations, appetite related hormones and energy intake in hormone receptor-positive breast cancer survivors. Appetite. 2022 Dec 17;182:106426. [Epub ahead of print] PubMed PMID: 36539160

Lin NU, Murthy RK, Abramson V, Anders C, Bachelot T, Bedard PL, Borges V, Cameron D, Carey LA, Chien AJ, Curigliano G, DiGiovanna MP, Gelmon K, Hortobagyi G, Hurvitz SA, Krop I, Loi S, Loibl S, Mueller V, Oliveira M, Paplomata E, Pegram M, Slamon D, Zelnak A, Ramos J, Feng W, Winer E. Tucatinib vs Placebo, Both in Combination With Trastuzumab and Capecitabine, for Previously Treated ERBB2 (HER2)-Positive Metastatic Breast Cancer in Patients With Brain Metastases: Updated Exploratory Analysis of the HER2CLIMB Randomized Clinical Trial. JAMA Oncol. 2022 Dec 1. [Epub ahead of print] PubMed PMID: 36454580

Rosenberg SM, Zheng Y, Gelber S, Ruddy KJ, Poorvu P, Sella T, Tamimi RM, Wassermann J, Schapira L, Borges VF, Come S, Peppercorn J, Sepucha KR, Partridge AH. Adjuvant endocrine therapy non-initiation and non-persistence in young women with early-stage breast cancer. Breast Cancer Res Treat. 2022 Nov 27. [Epub ahead of print] PubMed PMID: 36436128

Bilenduke E, Sterrett JD, Ranby KW, Borges VF, Grigsby J, Carr AL, Kilbourn K, Lowry CA. Impacts of breast cancer and chemotherapy on gut microbiome, cognitive functioning, and mood relative to healthy controls. Sci Rep. 2022 Nov 15;12(1):19547. PubMed PMID: 36380060

Sella T, Fell GG, Miller PG, Gibson CJ, Rosenberg SM, Snow C, Stover DG, Ruddy KJ, Peppercorn JM, Schapira L, Borges VF, Come SE, Warner E, Frank E, Neuberg DS, Ebert BL, Partridge AH. Patient perspectives on testing for clonal hematopoiesis of indeterminate potential. Blood Adv. 2022 Dec 27;6(24):6151-6161. PubMed PMID: 36129839

Tesch ME, Rosenberg SM, Collins LC, Wong JS, Dominici L, Ruddy KJ, Tamimi R, Schapira L, Borges VF, Warner E, Come SE, Partridge AH. ASO Visual Abstract: Clinicopathologic Features, Treatment Patterns, and Disease Outcomes in a Modern, Prospective Cohort of Young Women Diagnosed with Ductal Carcinoma In Situ. Ann Surg Oncol. 2022 Dec;29(13):8058-8059. PubMed PMID: 36038744

Krasne M, Ruddy KJ, Poorvu PD, Gelber SI, Tamimi RM, Schapira L, Peppercorn J, Come SE, Borges VF, Partridge AH, Rosenberg SM. Coping strategies and anxiety in young breast cancer survivors. Support Care Cancer. 2022 Nov;30(11):9109-9116. PubMed PMID: 35986100

Tesch ME, Rosenberg SM, Collins LC, Wong JS, Dominici L, Ruddy KJ, Tamimi R, Schapira L, Borges VF, Warner E, Come SE, Partridge AH. Clinicopathologic Features, Treatment Patterns, and Disease Outcomes in a Modern, Prospective Cohort of Young Women Diagnosed with Ductal Carcinoma In Situ. Ann Surg Oncol. 2022 Dec;29(13):8048-8057. PubMed PMID: 35960452

Sella T, Zheng Y, Tan-Wasielewski Z, Rosenberg SM, Poorvu PD, Tayob N, Ruddy KJ, Gelber SI, Tamimi RM, Schapira L, Come SE, Peppercorn JM, Borges VF, Partridge AH, Ligibel JA. Body weight changes and associated predictors in a prospective cohort of young breast cancer survivors. Cancer. 2022 Sep 1;128(17):3158-3169. PubMed PMID: 35775874

Shagisultanova E, Gao D, Callihan E, Parris HJ, Risendal B, Hines LM, Slattery ML, Baumgartner K, Schedin P, John EM, Borges VF. Overall survival is the lowest among young women with postpartum breast cancer. Eur J Cancer. 2022 Jun;168:119-127. PubMed PMID: 35525161

Shagisultanova E, Gradishar W, Brown-Glaberman U, Chalasani P, Brenner AJ, Stopeck A, Parris H, Gao D, McSpadden T, Mayordomo J, Diamond JR, Kabos P, Borges VF. Safety and Efficacy of Tucatinib, Letrozole, and Palbociclib in Patients with Previously Treated HR /HER2 Breast Cancer. Clin Cancer Res. 2023 Dec 15;29(24):5021-5030. PubMed PMID: 37363965

Rasti AR, Guimaraes-Young A, Datko F, Borges VF, Aisner DL, Shagisultanova E. PIK3CA Mutations Drive Therapeutic Resistance in Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer. JCO Precis Oncol. 2022 Mar;6:e2100370. PubMed PMID: 35357905

Waks AG, Kim D, Jain E, Snow C, Kirkner GJ, Rosenberg SM, Oh C, Poorvu PD, Ruddy KJ, Tamimi RM, Peppercorn J, Schapira L, Borges VF, Come SE, Brachtel EF, Warner E, Collins LC, Partridge AH, Wagle N. Somatic and Germline Genomic Alterations in Very Young Women with Breast Cancer. Clin Cancer Res. 2022 Jun 1;28(11):2339-2348. PubMed PMID: 35101884

Borstelmann NA, Gray TF, Gelber S, Rosenberg S, Zheng Y, Meyer M, Ruddy KJ, Schapira L, Come S, Borges V, Cadet T, Maramaldi P, Partridge AH. Psychosocial issues and quality of life of parenting partners of young women with breast cancer. Support Care Cancer. 2022 May;30(5):4265-4274. PubMed PMID: 35091846

Lipsyc-Sharf M, Jain E, Collins LC, Rosenberg SM, Ruddy KJ, Tamimi RM, Schapira L, Come SE, Peppercorn JM, Borges VF, Warner E, Snow C, Krop IE, Kim D, Weiss J, Zanudo JGT, Partridge AH, Wagle N, Waks AG. Genomics of ERBB2-Positive Breast Cancer in Young Women Before and After Exposure to Chemotherapy Plus Trastuzumab. JCO Precis Oncol. 2023 Jun;7:e2300076. PubMed PMID: 37364233

Curigliano G, Mueller V, Borges V, Hamilton E, Hurvitz S, Loi S, Murthy R, Okines A, Paplomata E, Cameron D, Carey LA, Gelmon K, Hortobagyi GN, Krop I, Loibl S, Pegram M, Slamon D, Ramos J, Feng W, Winer E. Tucatinib versus placebo added to trastuzumab and capecitabine for patients with pretreated HER2 metastatic breast cancer with and without brain metastases (HER2CLIMB): final overall survival analysis. Ann Oncol. 2022 Mar;33(3):321-329. PubMed PMID: 34954044

Borges VF. The Expanded Role of Ovarian Suppression for Young Women's Breast Cancer: An Era of Patient-Tailored Decision Making. J Natl Cancer Inst. 2022 Mar 8;114(3):342-344. PubMed PMID: 34850044

Guo Q, Sun D, Barrett AS, Jindal S, Pennock ND, Conklin MW, Xia Z, Mitchell E, Samatham R, Mirza N, Jacques S, Weinmann S, Borges VF, Hansen KC, Schedin PJ. Mammary collagen is under reproductive control with implications for breast cancer. Matrix Biol. 2022 Jan;105:104-126. PubMed PMID: 34839002

Shagisultanova E, Crump LS, Borakove M, Hall JK, Rasti AR, Harrison BA, Kabos P, Lyons TR, Borges VF. Triple Targeting of Breast Tumors Driven by Hormonal Receptors and HER2. Mol Cancer Ther. 2022 Jan;21(1):48-57. PubMed PMID: 34728571

Guzmán-Arocho YD, Rosenberg SM, Garber JE, Vardeh H, Poorvu PD, Ruddy KJ, Kirkner G, Snow C, Tamimi RM, Peppercorn J, Schapira L, Borges VF, Come SE, Brachtel EF, Marotti JD, Warner E, Partridge AH, Collins LC. Clinicopathological features and BRCA1 and BRCA2 mutation status in a prospective cohort of young women with breast cancer. Br J Cancer. 2022 Feb;126(2):302-309. PubMed PMID: 34703009

Schapira L, Zheng Y, Gelber SI, Poorvu P, Ruddy KJ, Tamimi RM, Peppercorn J, Come SE, Borges VF, Partridge AH, Rosenberg SM. Trajectories of fear of cancer recurrence in young breast cancer survivors. Cancer. 2022 Jan 15;128(2):335-343. PubMed PMID: 34614212

Elias AD, Spoelstra NS, Staley AW, Sams S, Crump LS, Vidal GA, Borges VF, Kabos P, Diamond JR, Shagisultanova E, Afghahi A, Mayordomo J, McSpadden T, Crawford G, D'Alessandro A, Zolman KL, van Bokhoven A, Zhuang Y, Gallagher RI, Wulfkuhle JD, Petricoin Iii EF, Gao D, Richer JK. Phase II trial of fulvestrant plus enzalutamide in ER /HER2- advanced breast cancer. NPJ Breast Cancer. 2023 May 20;9(1):41. PubMed PMID: 37210417

Kim HJ, Dominici L, Rosenberg SM, Zheng Y, Pak LM, Poorvu PD, Ruddy KJ, Tamimi R, Schapira L, Come SE, Peppercorn J, Borges VF, Warner E, Vardeh H, Collins LC, Gaither R, King TA, Partridge AH. Surgical Treatment After Neoadjuvant Systemic Therapy in Young Women With Breast Cancer: Results From a Prospective Cohort Study. Ann Surg. 2022 Jul 1;276(1):173-179. PubMed PMID: 33378304

Christian NT, Borges VF. What Dobbs Means for Patients with Breast Cancer. N Engl J Med. 2022 Sep 1;387(9):765-767. doi: 10.1056/NEJMp2209249. Epub 2022 Aug 27. PubMed PMID: 36026608

33. Borges VF. Options for Endocrine-Refractory, Hormone Receptor-Positive Breast Cancer: Which Target and When?. J Clin Oncol. 2021 Oct 28;:JCO2101910. doi: 10.1200/JCO.21.01910. [Epub ahead of print] PubMed PMID: 34709849.

Partridge AH, Niman SM, Ruggeri M, Peccatori FA, Azim HA Jr, Colleoni M, Saura C, Shimizu C, Sætersdal AB, Kroep JR, Mailliez A, Warner E, Borges VF, Amant F, Gombos A, Kataoka A, Rousset-Jablonski C, Borstnar S, Takei J, Lee JE, Walshe JM, Ruíz-Borrego M, Moore HCF, Saunders C, Bjelic-Radisic V, Susnjar S, Cardoso F, Smith KL, Ferreiro T, Ribi K, Ruddy K, Kammler R, El-Abed S, Viale G, Piccart M, Korde LA, Goldhirsch A, Gelber RD, Pagani O. Interrupting Endocrine Therapy to Attempt Pregnancy after Breast Cancer. N Engl J Med. 2023 May 4;388(18):1645-1656. PubMed PMID: 37133584

Lewinsohn R, Zheng Y, Rosenberg SM, Ruddy KJ, Tamimi RM, Schapira L, Peppercorn J, Borges VF, Come S, Snow C, Ginsburg ES, Partridge AH. Fertility Preferences and Practices Among Young Women With Breast Cancer: Germline Genetic Carriers Versus Noncarriers. Clin Breast Cancer. 2023 Apr;23(3):317-323. PubMed PMID: 36628811

Purcell SA, Melanson EL, Afghahi A, Borges VF, Sinelli I, Cornier MA. The effects of resistance exercise on appetite sensations, appetite related hormones and energy intake in hormone receptor-positive breast cancer survivors. Appetite. 2023 Mar 1;182:106426. PubMed PMID: 36539160

Rosenberg SM, Zheng Y, Gelber S, Ruddy KJ, Poorvu P, Sella T, Tamimi RM, Wassermann J, Schapira L, Borges VF, Come S, Peppercorn J, Sepucha KR, Partridge AH. Adjuvant endocrine therapy non-initiation and non-persistence in young women with early-stage breast cancer. Breast Cancer Res Treat. 2023 Feb;197(3):547-558. PubMed PMID: 36436128

Lin NU, Murthy RK, Abramson V, Anders C, Bachelot T, Bedard PL, Borges V, Cameron D, Carey LA, Chien AJ, Curigliano G, DiGiovanna MP, Gelmon K, Hortobagyi G, Hurvitz SA, Krop I, Loi S, Loibl S, Mueller V, Oliveira M, Paplomata E, Pegram M, Slamon D, Zelnak A, Ramos J, Feng W, Winer E. Tucatinib vs Placebo, Both in Combination With Trastuzumab and Capecitabine, for Previously Treated ERBB2 (HER2)-Positive Metastatic Breast Cancer in Patients With Brain Metastases: Updated Exploratory Analysis of the HER2CLIMB Randomized Clinical Trial. JAMA Oncol. 2023 Feb 1;9(2):197-205. PubMed PMID: 36454580

Brisson BK, Dekky B, Berger AC, Mauldin EA, Loebel C, Yen W, Stewart DC, Gillette D, Assenmacher CA, Cukierman E, Burdick JA, Borges VF, Volk SW. Tumor-restrictive type III collagen in the breast cancer microenvironment: prognostic and therapeutic implications. Res Sq. 2023 Apr 12. PubMed PMID: 37090621

Sella T, Zheng Y, Rosenberg SM, Ruddy KJ, Gelber SI, Tamimi RM, Peppercorn JM, Schapira L, Borges VF, Come SE, Carey LA, Winer EP, Partridge AH. Extended adjuvant endocrine therapy in a longitudinal cohort of young breast cancer survivors. NPJ Breast Cancer. 2023 Apr 25;9(1):31. PubMed PMID: 37185922

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