Zdenek Andrysik, PhD
Assistant Research Professor, Pharmacology

Publications

• Andrysik Z, Sullivan KD, Kieft JS, Espinosa JM. PPM1D suppresses p53-dependent transactivation and cell death by inhibiting the Integrated Stress Response. Nat Commun. 2022 Dec 1;13(1):7400. PubMed PMID: 36456590
• Karasová M, Procházková J, Tylichová Z, Fedr R, Ciganek M, Machala M, Dvorák Z, Vyhlídalová B, Zuvalová I, Ehrmann J, Bouchal J, Andrysík Z, Vondrácek J. Inhibition of Aryl Hydrocarbon Receptor (AhR) Expression Disrupts Cell Proliferation and Alters Energy Metabolism and Fatty Acid Synthesis in Colon Cancer Cells. Cancers (Basel). 2022 Aug 31;14(17). PubMed PMID: 36077780
• Galbraith MD, Andrysik Z, Sullivan KD, Espinosa JM. Global Analyses to Identify Direct Transcriptional Targets of p53. Methods Mol Biol. 2021;2267:19-56. PubMed PMID: 33786783
• Andrysik Z, Bender H, Galbraith MD, Espinosa JM. Multi-omics analysis reveals contextual tumor suppressive and oncogenic gene modules within the acute hypoxic response. Nat Commun. 2021 Mar 2;12(1):1375. PubMed PMID: 33654095
• Hýždalová M, Procházková J, Strapácová S, Svržková L, Vacek O, Fedr R, Andrysík Z, Hrubá E, Líbalová H, Kléma J, Topinka J, Mašek J, Soucek K, Vondrácek J, Machala M. A prolonged exposure of human lung carcinoma epithelial cells to benzo[a]pyrene induces p21-dependent epithelial-to-mesenchymal transition (EMT)-like phenotype. Chemosphere. 2021 Jan;263:128126. PubMed PMID: 33297115
• Sullivan KD, Galbraith MD, Andrysik Z, Espinosa JM. Mechanisms of transcriptional regulation by p53. Cell Death Differ. 2018 Jan;25(1):133-143. PubMed PMID: 29125602
• Galbraith MD, Andrysik Z, Pandey A, Hoh M, Bonner EA, Hill AA, Sullivan KD, Espinosa JM. CDK8 Kinase Activity Promotes Glycolysis. Cell Rep. 2017 Nov 7;21(6):1495-1506. PubMed PMID: 29117556
• Andrysik Z, Galbraith MD, Guarnieri AL, Zaccara S, Sullivan KD, Pandey A, MacBeth M, Inga A, Espinosa JM. Identification of a core TP53 transcriptional program with highly distributed tumor suppressive activity. Genome Res. 2017 Oct;27(10):1645-1657. PubMed PMID: 28904012