Rooban Nahomi, PhD

Research Scientist, Ophthalmology

Faculty Photo
Department
Ophthalmology

Publications

  • Nahomi RB, Nandi SK, Rakete S, Michel C, Fritz KS, Nagaraj RH. Lysine malonylation and propionylation are prevalent in human lens proteins. Exp Eye Res. 2020 Jan;190:107864. PubMed PMID: 31678036
  • Nahomi RB, Nandi SK, Rakete S, Michel C, Fritz KS, Nagaraj RH. Lysine malonylation and propionylation are prevalent in human lens proteins. Exp Eye Res. 2020 Jan;190:107864. PubMed PMID: 31678036
  • Nahomi RB, Nam MH, Rankenberg J, Rakete S, Houck JA, Johnson GC, Stankowska DL, Pantcheva MB, MacLean PS, Nagaraj RH. Kynurenic Acid Protects Against Ischemia/Reperfusion-Induced Retinal Ganglion Cell Death in Mice. Int J Mol Sci. 2020 Mar 5;21(5). PubMed PMID: 32151061
  • Nandi SK, Nahomi RB, Rankenberg J, Glomb MA, Nagaraj RH. Glycation-mediated inter-protein cross-linking is promoted by chaperone-client complexes of a-crystallin: Implications for lens aging and presbyopia. J Biol Chem. 2020 Apr 24;295(17):5701-5716. PubMed PMID: 32184356
  • Nandi SK, Rankenberg J, Rakete S, Nahomi RB, Glomb MA, Linetsky MD, Nagaraj RH. Glycation-mediated protein crosslinking and stiffening in mouse lenses are inhibited by carboxitin in vitro. Glycoconj J. 2020 Nov 27. [Epub ahead of print] PubMed PMID: 33245448
  • Nandi SK, Nahomi RB, Harris PS, Michel CR, Fritz KS, Nagaraj RH. The absence of SIRT3 and SIRT5 promotes the acetylation of lens proteins and improves the chaperone activity of a-crystallin in mouse lenses. Exp Eye Res. 2019 May;182:1-9. PubMed PMID: 30849386
  • Nandi SK, Rakete S, Nahomi RB, Michel C, Dunbar A, Fritz KS, Nagaraj RH. Succinylation Is a Gain-of-Function Modification in Human Lens aB-Crystallin. Biochemistry. 2019 Mar 5;58(9):1260-1274. PubMed PMID: 30758948
  • Nahomi RB, Nandi SK, Nagaraj RH. A monoclonal antibody targeted to the functional peptide of aB-crystallin inhibits the chaperone and anti-apoptotic activities. J Immunol Methods. 2019 Apr;467:37-47. PubMed PMID: 30738041
  • Stankowska DL, Nam MH, Nahomi RB, Chaphalkar RM, Nandi SK, Fudala R, Krishnamoorthy RR, Nagaraj RH. Systemically administered peptain-1 inhibits retinal ganglion cell death in animal models: implications for neuroprotection in glaucoma. Cell Death Discov. 2019;5:112. PubMed PMID: 31285855
  • Nahomi RB, Nagaraj RH. The role of HIF-1a in the TGF-ß2-mediated epithelial-to-mesenchymal transition of human lens epithelial cells. J Cell Biochem. 2018 Aug;119(8):6814-6827. PubMed PMID: 29693273
  • Nahomi RB, Sampathkumar S, Myers AM, Elghazi L, Smith DG, Tang J, Lee CA, Kern TS, Nagaraj RH, Fort PE. The Absence of Indoleamine 2,3-Dioxygenase Inhibits Retinal Capillary Degeneration in Diabetic Mice. Invest Ophthalmol Vis Sci. 2018 Apr 1;59(5):2042-2053. PubMed PMID: 29677366
  • IOVS-ARVO
  • Nahomi RB, Pantcheva MB, Nagaraj RH. aB-crystallin is essential for the TGF-ß2-mediated epithelial to mesenchymal transition of lens epithelial cells. Biochem J. 2016 May 15;473(10):1455-69. PubMed PMID: 26987815
  • Nagaraj RH, Nahomi RB, Mueller NH, Raghavan CT, Ammar DA, Petrash JM. Therapeutic potential of a-crystallin. Biochim Biophys Acta. 2016 Jan;1860(1 Pt B):252-7. PubMed PMID: 25840354
  • A Monoclonal Antibody Targeted to the Functional Peptide of aB-Crystallin Inhibits the Chaperone and Anti-apoptotic Activities
  • Retinal Ganglion Cells are Protected from Ischemia/Reperfusion-Induced Death in Mice Lacking Kynurenine 3-Monooxygenase
  • Succinylation is a Gain-of-Function Modification in Human Lens aB-Crystallin
  • The Absence of SIRT3 and SIRT5 Promotes the Acetylation of Lens Proteins and Improves the Chaperone Activity of a-Crystallin in Mouse Lenses
  • The 2018 SSPPS Research Retreat. Retinal Ganglion Cells are Protected from Ischemia/Reperfusion-Induced Death in Mice Lacking Kynurenine 3-Monooxygenase
View All (19 Total) View Less

School of Medicine

CU Anschutz

Fitzsimons Building

13001 East 17th Place

Campus Box C290

Aurora, CO 80045


303.724.5375