Beth Warren, MD
Assistant Professor, Pediatrics-Heme/Onc and Bone Marrow Transplantation
Medical School
- MD, University of Texas Southwestern Medical Center at Dallas Southwestern Medical School (2009)
Graduate Schools
- MS, Emory University (2005)
- MSc, University of Colorado Health Sciences Center (2019)
Undergraduate School
- BS, Rice University (TX) (2002)
Residency
- University of Colorado (Children's Hospital Colorado) Program, Pediatrics (2012)
Fellowships
- University of Colorado (Children's Hospital Colorado) Program, Pediatric Hematology / Oncology (2015)
- University of Colorado (Children's Hospital Colorado) Program, Pediatric Hemostasis and Thrombosis
Languages
EnglishDepartment
Pediatrics-Heme/Onc and Bone Marrow TransplantationProfessional Titles
- Assistant Professor, Department of Pediatrics
Research Interests
My primary research interest is hemophilia. My research goal is to eliminate breakthrough bleeding by better understanding the biomechanics of joint and muscle bleeding, and by better understanding what factor levels are needed to prevent breakthrough bleeding in specific situations.Publications
- Warren BB, Smith N, Blades T, Wang M, Manco-Johnson MJ. Breakthrough Bleeding in Hemophilia A Patients on Prophylaxis. American Society of Hematology Meeting, San Diego, CA, December 4, 2016. 2016.
- Warren BB, Branchford B, Perspective: Recombinant Factor VIII Products Increase Inhibitor Development in Severe Hemophilia A, HemOnc Today, February 10, 2016. http://www.healio.com/hematology-oncology/hematology/news/online/%7Bbdb240db-c3d2-4eea-914e-91ef07e76f21%7D/recombinant-factor-viii-products-increase-inhibitor-development-in-severe-hemophilia-a
- Warren BB, Young G, Wang M. Recombinant Factor VIII Concentrates Associated with Increased Risk of Inhibitor Development in Severe Hemophilia A: Results of the SIPPET Trial, AAP News, In Press
- Warren BB, Jacobson L, Kempton C, Buchanan GR, Recht M, Brown D, Leissinger C, Shapiro AD, Abshire TC, Manco-Johnson MJ. Factor VIII prophylaxis effects outweigh other hemostasis contributors in predicting severe haemophilia A joint outcomes. Haemophilia. 2019 Sep;25(5):867-875. PubMed PMID: 31115111
- Yu JK, Iorio A, Edginton AN, and the WAPPS Co-investigators. Using pharmacokinetics for tailoring prophylaxis in people with hemophilia switching between clotting factor products: A scoping review. Res Pract Thromb Haemost. 2019 Jul;3(3):528-541. PubMed PMID: 31294337
- McKinney C, Warren BB, Harvey S. Newborn Hematology. In: Gardner SL, S. CB, I. E-HM, S. N, eds. Merenstein and Gardner's Handbook of Neonatal Intensive Care: Elsevier; 2021.
- Warren BB, Thornhill D, Stein J, Fadell M, Ingram JD, Funk S, Norton KL, Lane HD, Bennett CM, Dunn A, Recht M, Shapiro A, Manco-Johnson MJ. Young adult outcomes of childhood prophylaxis for severe hemophilia A: results of the Joint Outcome Continuation Study. Blood Adv. 2020 Jun 9;4(11):2451-2459. PubMed PMID: 32492157
- Slatnick LR, Thornhill D, Deakyne Davies SJ, Ford JB, Scott HF, Manco-Johnson MJ, Warren BB. Disseminated Intravascular Coagulation Is an Independent Predictor of Adverse Outcomes in Children in the Emergency Department with Suspected Sepsis. J Pediatr. 2020 Oct;225:198-206.e2. PubMed PMID: 32553867
- Maher KN, Gibson E, Warren BB, Funk SM, Shearer R, Buckner TW, Wang M, Manco-Johnson MJ, Ng CJ. Prophylaxis for children with moderate hemophilia: Use of a guideline to increase early initiation. Pediatr Blood Cancer. 2020 Sep 2;:e28577. [Epub ahead of print] PubMed PMID: 32881253
- Warren BB, Chan A, Manco-Johnson M, Branchford BR, Buckner TW, Moyer G, Gibson E, Thornhill D, Wang M, Ng CJ. Emicizumab initiation and bleeding outcomes in people with hemophilia A with and without inhibitors: A single-center report. Res Pract Thromb Haemost. 2021 Jul;5(5):e12571. PubMed PMID: 34377887
- Smith N, Warren BB, Smith J, Jacobson L, Armstrong J, Kim J, Di Paola J, Manco-Johnson M. Antithrombin deficiency: A pediatric disorder. Thromb Res. 2021 Jun;202:45-51. PubMed PMID: 33725558
- Smith J, Thornhill D, Goldenberg NA, Brandão L, Knapp-Clevenger R, Warren BB, Sung L, Kahn SR, Manco-Johnson M. Validation of Outcome Instruments for Pediatric Postthrombotic Syndrome: Introducing the Peds-VEINES-QOL, a New Health-Related Quality of Life Instrument. Thromb Haemost. 2021 Oct;121(10):1367-1375. PubMed PMID: 33706398
- Manco-Johnson MJ, Warren BB, Buckner TW, Funk SM, Wang M. Outcome measures in Haemophilia: Beyond ABR (Annualized Bleeding Rate). Haemophilia. 2021 Feb;27 Suppl 3:87-95. PubMed PMID: 33398908
- Warren BB. Untreated bleeds: Unveiling the subtleties and challenges of bleeding event counts and patient experience in clinical trials for bleeding disorders. Research and Practice in Thrombosis and Haemostasis. 2022;6(7):e12832.
- Manco-Johnson MJ, Warren BB. Long-term prophylaxis: what are our options and how do we define success. ASH education 2022.
- Warren BB, Moyer GC, Manco-Johnson MJ. Hemostasis in the Pregnant Woman, the Placenta, the Fetus, and the Newborn Infant, Seminars in Thrombosis and Hemostasis
- Maher KN, Gibson E, Warren BB, Funk SM, Shearer R, Buckner TW, Wang M, Manco-Johnson MJ, Ng CJ. Prophylaxis for children with moderate hemophilia: Use of a guideline to increase early initiation. Pediatr Blood Cancer. 2021 Jan;68(1):e28577. PubMed PMID: 32881253
- Slatnick LR, Thornhill D, Deakyne Davies SJ, Ford JB, Scott HF, Manco-Johnson MJ, Warren BB. Disseminated Intravascular Coagulation Is an Independent Predictor of Adverse Outcomes in Children in the Emergency Department with Suspected Sepsis. J Pediatr. 2020 Oct;225:198-206.e2. PubMed PMID: 32553867
- Ng CJ, Spomer N, Shearer R, LeBlanc A, Funk S, Manco-Johnson M, Branchford B, Warren B, Buckner TW, Cowell A, Moyer G, Wang M, Gibson E, Mashburn C. Improvements in Communication and Coordination of Care in a Hemophilia Treatment Center. Acta Haematol. 2021 Apr 29;:1-6. [Epub ahead of print] PubMed PMID: 33915533
- Byams VR, Baker JR, Bailey C, Connell NT, Creary MS, Curtis RG, Dinno A, Guelcher CJ, Kim M, Kulkarni R, Lattimore S, Norris KL, Ramirez L, Skinner MW, Symington S, Tobase P, Vázquez E, Warren BB, Wheat E, Buckner TW. Building the foundation for a community-generated national research blueprint for inherited bleeding disorders: research priorities in health services; diversity, equity, and inclusion; and implementation science. Expert Rev Hematol. 2023 Mar;16(sup1):87-106. PubMed PMID: 36920863
- Mah J, Robertson C, Mah N, Roybal J, Thornhill D, Funk S, Manco-Johnson MJ, Carollo J, Gaffney BMM, Warren BB. Joint Reaction and Simulated Muscle Forces during Squatting and Walking in Persons with Hemophilia, Clinical Biomechanics, In press
- Jewell MP, Ashour Z, Baird CH, Manco Johnson M, Warren BB, Wufsus AR, Pallini C, Dockal M, Kjalke M, Neeves KB. Concizumab improves clot formation in hemophilia A under flow. J Thromb Haemost. 2024 Sep;22(9):2438-2448. PubMed PMID: 38815755
- Byams VR, Baker JR, Bailey C, Connell NT, Creary MS, Curtis RG, Dinno A, Guelcher CJ, Kim M, Kulkarni R, Lattimore S, Norris KL, Ramirez L, Skinner MW, Symington S, Tobase P, Vázquez E, Warren BB, Wheat E, Buckner TW. Building the foundation for a community-generated national research blueprint for inherited bleeding disorders: research priorities in health services; diversity, equity, and inclusion; and implementation science. Expert Rev Hematol. 2023 Mar;16(sup1):87-106. PubMed PMID: 36920863
- Warren BB, Moyer GC, Manco-Johnson MJ. Hemostasis in the Pregnant Woman, the Placenta, the Fetus, and the Newborn Infant. Semin Thromb Hemost. 2023 Jun;49(4):319-329. PubMed PMID: 36750218
- McKinney C, Warren BB, Harvey S. Newborn Hematology. In: Gardner SL, S. CB, I. E-HM, S. N, eds. Merenstein and Gardner's Handbook of Neonatal Intensive Care: Elsevier; 2024.
Practice Locations
Children's Hospital Colorado Anschutz Medical Campus13123 East 16th Ave
Aurora, CO 80045
720-777-1234
Hemophilia & Thrombosis Center - CU Anschutz Medical Campus
13199 E. Montview Blvd
Suite 100
Aurora, CO 80045
303-724-0724
Hospital Affiliation
- Children's Hospital Colorado
Center Affiliations
Specialty Information
Specialties- Pediatric Hematology / Oncology, Board Certification
- Pediatrics, Board Certification
- Blood / Lymphatic System - Bleeding Disorders
- Blood / Lymphatic System
- Blood / Lymphatic System - Clotting Disorders
Clinical Interests
Hemophilia, bleeding disorders, clotting disorders, clots in congenital heart disease, heavy menstrual bleeding
Care Philosophy
My goal is to help patients manage their bleeding or clotting problems in an integrative way that focuses on enjoying life and minimizing long-term effects.
Hemophilia, bleeding disorders, clotting disorders, clots in congenital heart disease, heavy menstrual bleeding
Care Philosophy
My goal is to help patients manage their bleeding or clotting problems in an integrative way that focuses on enjoying life and minimizing long-term effects.
Personal Interests
My personal research interest is to better prevent bleeding in patients with hemophilia. I think that bleeding happens in joints and muscles when the amount of factor medication in the body is too low to prevent bleeding when joints and muscles are stressed by physical activities. I am collaborating with our orthopedics department to better understand the physical stresses on joints and muscles during activities, so that we can better tailor factor medication dosing to prevent bleeding.
My personal research interest is to better prevent bleeding in patients with hemophilia. I think that bleeding happens in joints and muscles when the amount of factor medication in the body is too low to prevent bleeding when joints and muscles are stressed by physical activities. I am collaborating with our orthopedics department to better understand the physical stresses on joints and muscles during activities, so that we can better tailor factor medication dosing to prevent bleeding.