Matthew Zipse, MD
Associate Professor, Medicine-Cardiology

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Medical School:
  • MD, Indiana University School of Medicine (2008)
Undergraduate School:
  • BS, Indiana University–Bloomington (IN) (2004)
Internship:
  • University of Colorado (2009)
Residency:
  • University of Colorado, Internal Medicine (2011)
Fellowships:
  • University of Colorado, General Cardiology (2013)
  • University of Colorado, Cardiac Electrophysiology (2015)
Languages: English
Department: Medicine-Cardiology

Recognition & Awards

  • Clinical Excellence Society, CU, Department of Medicine (2023)

Publications

  • Sandhu A, Holman B, Lammers S, Cerbin L, Barrett C, Sabzwari R, Garg L, Zipse MM, Tumolo AZ, Aleong RG, Von Alvensleben J, Rosenberg M, West JJ, Varosy P, Nguyen DT, Sauer WH, Tzou WS. Evaluating temperature gradients across the posterior left atrium with radiofrequency ablation. J Cardiovasc Electrophysiol. 2023 Jan 22. [Epub ahead of print] PubMed PMID: 36682068
  • Myadam R, Crawford TC, Bogun FM, Gu X, Ellenbogen KA, Jasti S, Chicos AB, Roukoz H, Zimetbaum PJ, Kalbfleisch SJ, Murgatroyd FD, Steckman DA, Rosenfeld LE, Garlitski AC, Soejima K, Bhan AK, Vedantham V, Dickfeld TL, De Lurgio DB, Platonov PG, Zipse MM, Nishiuchi S, Ortman ML, Narasimhan C, Patton KK, Rosenthal DG, Mukerji SS, Hoogendoorn JC, Zeppenfeld K, Sauer WH, Kron J. Reply: Association of Adverse Events With the Different Diagnostic Schemes of Cardiac Sarcoidosis. JACC Clin Electrophysiol. 2023 Dec;9(12):2662-2663. PubMed PMID: 38151306
  • Sundaram S, Alyesh D, Walker L, Zipse MM. The 1(st) implantation of an atrial only leadless pacemaker in right atrial appendage. J Interv Card Electrophysiol. 2023 Dec;66(9):1955-1958. PubMed PMID: 37773557
  • Barrett CD, Nickel A, Rosenberg MA, Ream K, Tzou WS, Aleong R, Tumolo A, Garg L, Zipse M, West JJ, Varosy P, Sandhu A. PRIME score for prediction of permanent pacemaker implantation after transcatheter aortic valve replacement. Catheter Cardiovasc Interv. 2023 Dec;102(7):1357-1363. PubMed PMID: 37735946
  • Ashur C, Zirille F, Aleong RG, Varosy PD, West JJ, Sandhu A, Tumolo AZ, Rosenberg MA, Sabzwari SRA, Barrett C, Cerbin L, Saqi B, Varela D, Zipse MM, Tzou WS, Garg L. Right versus left-sided implantation of left bundle branch area pacemaker insertion. J Interv Card Electrophysiol. 2023 Sep 21. [Epub ahead of print] PubMed PMID: 37731143
  • Myadam R, Crawford TC, Bogun FM, Gu X, Ellenbogen KA, Jasti S, Chicos AB, Roukoz H, Zimetbaum PJ, Kalbfleisch SJ, Murgatroyd FD, Steckman DA, Rosenfeld LE, Garlitski AC, Soejima K, Bhan AK, Vedantham V, Dickfeld TL, De Lurgio DB, Platonov PG, Zipse MM, Nishiuchi S, Ortman ML, Narasimhan C, Patton KK, Rosenthal DG, Mukerji SS, Hoogendoorn JC, Zeppenfeld K, Sauer WH, Kron J. Risk of Adverse Outcomes Associated With Cardiac Sarcoidosis Diagnostic Schemes. JACC Clin Electrophysiol. 2023 Aug;9(8 Pt 3):1719-1729. PubMed PMID: 37227359
  • Barrett CD, Suzuki Y, Hussein S, Garg L, Tumolo A, Sandhu A, West JJ, Zipse M, Aleong R, Varosy P, Tzou WS, Banaei-Kashani F, Rosenberg MA. Evaluation of Quantitative Decision-Making for Rhythm Management of Atrial Fibrillation Using Tabular Q-Learning. J Am Heart Assoc. 2023 May 2;12(9):e028483. PubMed PMID: 37119087
  • Sandhu A, Holman B, Lammers S, Cerbin L, Barrett C, Sabzwari R, Garg L, Zipse MM, Tumolo AZ, Aleong RG, Von Alvensleben J, Rosenberg M, West JJ, Varosy P, Nguyen DT, Sauer WH, Tzou WS. Evaluating temperature gradients across the posterior left atrium with radiofrequency ablation. J Cardiovasc Electrophysiol. 2023 Apr;34(4):880-887. PubMed PMID: 36682068
  • Zipse MM. Editorial commentary: Cardiac sarcoidosis in contemporary practice: Forward progress, but clinical quandaries persist. Trends Cardiovasc Med. 2023 Oct;33(7):456-457. PubMed PMID: 35798173
  • Siontis KC, Santangeli P, Muser D, Marchlinski FE, Zeppenfeld K, Hoogendoorn JC, Narasimhan C, Sauer WH, Zipse MM, Kapa S, Vedantham V, Rosenthal DG, Robinson MR, Patton KK, Murgatroyd F, Chicos AB, Soejima K, Roukoz H, Sacher F, Bhan A, Appelbaum J, Dickfeld T, Mankad P, Ellenbogen KA, Kron J, Kim HM, Froehlich J, Eagle KA, Bogun FM, Crawford TC. Outcomes Associated With Catheter Ablation of Ventricular Tachycardia in Patients With Cardiac Sarcoidosis. JAMA Cardiol. 2022 Feb 1;7(2):175-183. PubMed PMID: 34787643
  • Zipse MM. Cardiac sarcoidosis in contemporary practice: Forward progress, but clinical quandaries persist. Trends Cardiovasc Med. 2022 Jul 4. [Epub ahead of print] PubMed PMID: 35798173
  • Bressi E, Crawford TC, Bogun FM, Gu X, Ellenbogen KA, Chicos AB, Roukoz H, Zimetbaum PJ, Kalbfleisch SJ, Murgatroyd FD, Steckman DA, Rosenfeld LE, Garlitski AC, Soejima K, Bhan AK, Vedantham V, Dickfeld TM, De Lurgio DB, Platonov PG, Zipse MM, Nishiuchi S, Ortman ML, Narasimhan C, Patton KK, Rosenthal DG, Mukerji SS, Hoogendoorn JC, Zeppenfeld K, Sauer WH, Kron J. Arrhythmia Monitoring and Outcomes in Patients With Cardiac Sarcoidosis: Insights From the Cardiac Sarcoidosis Consortium. J Am Heart Assoc. 2022 Jul 5;11(13):e024924. PubMed PMID: 35730638
  • Sabzwari SRA, Rosenberg MA, Mann J, Cerbin L, Barrett C, Garg L, Aleong RG, Sandhu A, West J, Tumolo AZ, Varosy PD, Sauer WH, Zipse MM, Tzou WS. Limitations of Unipolar Signals in Guiding Successful Outflow Tract Premature Ventricular Contraction Ablation. JACC Clin Electrophysiol. 2022 Jul;8(7):843-853. PubMed PMID: 35643806
  • Siontis KC, Santangeli P, Muser D, Marchlinski FE, Zeppenfeld K, Hoogendoorn JC, Narasimhan C, Sauer WH, Zipse MM, Kapa S, Vedantham V, Rosenthal DG, Robinson MR, Patton KK, Murgatroyd F, Chicos AB, Soejima K, Roukoz H, Sacher F, Bhan A, Appelbaum J, Dickfeld T, Mankad P, Ellenbogen KA, Kron J, Kim HM, Froehlich J, Eagle KA, Bogun FM, Crawford TC. Outcomes Associated With Catheter Ablation of Ventricular Tachycardia in Patients With Cardiac Sarcoidosis. JAMA Cardiol. 2022 Feb 1;7(2):175-183. PubMed PMID: 34787643
  • Varela DL, Rosenberg MA, Borne RT, Sandhu A, Zipse MM, Tzou WS, Sauer WH, Scheinman MM, Nguyen DT. Increased incidence of cavotricuspid isthmus atrial flutter following slow pathway ablation. J Interv Card Electrophysiol. 2022 Apr;63(3):581-589. PubMed PMID: 34532821
  • Borne RT, Masoudi FA, Curtis JP, Zipse MM, Sandhu A, Hsu JC, Peterson PN. Use and Outcomes of Dual Chamber or Cardiac Resynchronization Therapy Defibrillators Among Older Patients Requiring Ventricular Pacing in the National Cardiovascular Data Registry Implantable Cardioverter Defibrillator Registry. JAMA Netw Open. 2021 Jan 4;4(1):e2035470. PubMed PMID: 33496796
  • Sandhu A, Tzou WS, Borne RT, Zipse MM, Nguyen DT, Sauer WH. Uncovering a unique path: Antidromic AVRT utilizing a left anteroseptal Mahaim-like accessory pathway. Pacing Clin Electrophysiol. 2021 Jan;44(1):185-188. PubMed PMID: 32794265
  • Kim RS, Simon S, Powers B, Sandhu A, Sanchez J, Borne RT, Tumolo A, Zipse M, West JJ, Aleong R, Tzou W, Rosenberg MA. Machine Learning Methodologies for Prediction of Rhythm-Control Strategy in Patients Diagnosed With Atrial Fibrillation: Observational, Retrospective, Case-Control Study. JMIR Med Inform. 2021 Dec 6;9(12):e29225. PubMed PMID: 34874889
  • Varela DL, Rosenberg MA, Borne RT, Sandhu A, Zipse MM, Tzou WS, Sauer WH, Scheinman MM, Nguyen DT. Increased incidence of cavotricuspid isthmus atrial flutter following slow pathway ablation. J Interv Card Electrophysiol. 2021 Sep 17. [Epub ahead of print] PubMed PMID: 34532821
  • Borne RT, Masoudi FA, Curtis JP, Zipse MM, Sandhu A, Hsu JC, Peterson PN. Use and Outcomes of Dual Chamber or Cardiac Resynchronization Therapy Defibrillators Among Older Patients Requiring Ventricular Pacing in the National Cardiovascular Data Registry Implantable Cardioverter Defibrillator Registry. JAMA Netw Open. 2021 Jan 4;4(1):e2035470. PubMed PMID: 33496796
  • Sandhu A, Tzou WS, Borne RT, Zipse MM, Nguyen DT, Sauer WH. Uncovering a unique path: Antidromic AVRT utilizing a left anteroseptal Mahaim-like accessory pathway. Pacing Clin Electrophysiol. 2021 Jan;44(1):185-188. PubMed PMID: 32794265
  • Kunkel M, Rothstein P, Sauer P, Zipse MM, Sandhu A, Tumolo AZ, Borne RT, Aleong RG, Cleveland JC Jr, Fullerton D, Pal JD, Davies AS, Lane C, Nguyen DT, Sauer WH, Tzou WS. Open surgical ablation of ventricular tachycardia: Utility and feasibility of contemporary mapping and ablation tools. Heart Rhythm O2. 2021 Jun;2(3):271-279. PubMed PMID: 34337578
  • Aleong RG, Zipse MM, Tompkins C, Aftab M, Varosy P, Sauer W, Kao D. Analysis of Outcomes in 8304 Patients Undergoing Lead Extraction for Infection. J Am Heart Assoc. 2020 Apr 7;9(7):e011473. PubMed PMID: 32192410
  • Zipse MM, Edward JA, Zheng L, Tzou WS, Borne RT, Sauer WH, Nguyen DT. Impact of epicardial adipose tissue and catheter ablation strategy on biophysical parameters and ablation lesion characteristics. J Cardiovasc Electrophysiol. 2020 May;31(5):1114-1124. PubMed PMID: 32031304
  • Cornwell WK, Tran T, Cerbin L, Coe G, Muralidhar A, Hunter K, Altman N, Ambardekar AV, Tompkins C, Zipse M, Schulte M, O'Gean K, Ostertag M, Hoffman J, Pal JD, Lawley JS, Levine BD, Wolfel E, Kohrt WM, Buttrick P. New insights into resting and exertional right ventricular performance in the healthy heart through real-time pressure-volume analysis. J Physiol. 2020 Jul;598(13):2575-2587. PubMed PMID: 32347547
  • Zipse MM, Tzou WS. Resynchronization Therapy in Cardiac Sarcoidosis and Severe Heart Failure: When Good May Not Be Good Enough. J Cardiovasc Electrophysiol. 2017 Feb;28(2):182-184. PubMed PMID: 27925330
  • Zipse MM, Nguyen DT. Near-Field Ultrasound Imaging of Ablation Lesion Formation: More Than Meets the Eye?. Circ Arrhythm Electrophysiol. 2017 Dec;10(12). PubMed PMID: 29242237
  • Zipse MM, Tzou WS. Sudden cardiac death in nonischemic cardiomyopathy: Refining risk assessment. J Cardiovasc Electrophysiol. 2017 Nov;28(11):1361-1366. PubMed PMID: 28670752
  • Zipse MM, Tzou WS. Resynchronization Therapy in Cardiac Sarcoidosis and Severe Heart Failure: When Good May Not Be Good Enough. J Cardiovasc Electrophysiol. 2017 Feb;28(2):182-184. PubMed PMID: 27925330
  • Zipse MM, Groves DW, Khanna AD, Nguyen DT. An Approach to Endovascular Ventricular Pacing in a Patient with Ebstein Anomaly and a Mechanical Tricuspid Valve. Card Electrophysiol Clin. 2016 Mar;8(1):169-71. PubMed PMID: 26920188
  • Zipse MM, Nguyen DT. Ablation of Atrial Fibrillation in a Patient with a Mechanical Mitral Valve. Card Electrophysiol Clin. 2016 Mar;8(1):155-9. PubMed PMID: 26920185
  • Zipse MM, Aleong RG. Acquired Pulmonary Vein Isolation in a Patient with Friedreich Ataxia. Card Electrophysiol Clin. 2016 Mar;8(1):151-3. PubMed PMID: 26920184
  • Gonzalez JE, Zipse MM, Nguyen DT, Sauer WH. Antidromic Atrioventricular Reciprocating Tachycardia Using a Concealed Retrograde Conducting Left Lateral Accessory Pathway. Card Electrophysiol Clin. 2016 Mar;8(1):37-43. PubMed PMID: 26920167
  • Zipse MM, Messenger JC, Carroll JD, Seres T. Percutaneous repair of right ventricular perforation with Amplatzer septal defect occlusion device. Eur Heart J. 2016 Dec 23. [Epub ahead of print] PubMed PMID: 28025192
  • Nguyen DT, Tzou WS, Brunnquell M, Zipse M, Schuller JL, Zheng L, Aleong RA, Sauer WH. Clinical and biophysical evaluation of variable bipolar configurations during radiofrequency ablation for treatment of ventricular arrhythmias. Heart Rhythm. 2016 Nov;13(11):2161-2171. PubMed PMID: 27424078
  • Moss TJ, Zipse MM, Krantz MJ, Sauer WH, Salcedo EE, Schuller JL. Incidence of Atrial Fibrillation following Alcohol Septal Ablation for Hypertrophic Cardiomyopathy. Ann Noninvasive Electrocardiol. 2016 Sep;21(5):443-9. PubMed PMID: 26970562
  • Zipse MM, Groves DW, Khanna AD, Nguyen DT. An Approach to Endovascular Ventricular Pacing in a Patient with Ebstein Anomaly and a Mechanical Tricuspid Valve. Card Electrophysiol Clin. 2016 Mar;8(1):169-71. PubMed PMID: 26920188
  • Zipse MM, Nguyen DT. Ablation of Atrial Fibrillation in a Patient with a Mechanical Mitral Valve. Card Electrophysiol Clin. 2016 Mar;8(1):155-9. PubMed PMID: 26920185
  • Zipse MM, Aleong RG. Acquired Pulmonary Vein Isolation in a Patient with Friedreich Ataxia. Card Electrophysiol Clin. 2016 Mar;8(1):151-3. PubMed PMID: 26920184
  • Gonzalez JE, Zipse MM, Nguyen DT, Sauer WH. Antidromic Atrioventricular Reciprocating Tachycardia Using a Concealed Retrograde Conducting Left Lateral Accessory Pathway. Card Electrophysiol Clin. 2016 Mar;8(1):37-43. PubMed PMID: 26920167
  • Zipse MM, Sauer WH. Cardiac sarcoidosis and consequent arrhythmias. Card Electrophysiol Clin. 2015 Jun;7(2):235-49. PubMed PMID: 26002389
  • Schuller JL, Zipse MM, Krantz MJ, Blaker B, Salcedo E, Groves BM, Messenger JC, Beaty B, Sauer WH. Incidence and predictors of late complete heart block after alcohol septal ablation treatment of hypertrophic obstructive cardiomyopathy. J Interv Cardiol. 2015 Feb;28(1):90-7. PubMed PMID: 25689552
  • Katz DF, Turakhia MP, Sauer WH, Tzou WS, Heath RR, Zipse MM, Aleong RG, Varosy PD, Kao DP. Safety of ventricular tachycardia ablation in clinical practice: findings from 9699 hospital discharge records. Circ Arrhythm Electrophysiol. 2015 Apr;8(2):362-70. PubMed PMID: 25688143
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Professional Memberships

  • American College of Cardiology (ACC), Member
  • Heart Rhythm Society (HRS), Member

Practice Locations

UCHealth Heart & Vascular Center - Anschutz
12505 E. 16th Ave
Anschutz Inpatient Pavilion 2, 3rd floor
Aurora, CO 80045
720-848-5300

Denver Veterans Affairs Medical Center
1055 Clermont St
Denver, CO 80220
1-888-336-8262

UCHealth University of Colorado Hospital (UCH)
12605 E. 16th Ave
Aurora, CO 80045
720-848-0000

Cardiac Electrophysiology - Anschutz
12505 E. 16th Ave
3rd Floor
Aurora, CO 80045
720-848-6510

CU Medicine Cardiology - Cherry Creek Medical Center
100 Cook Street
Suite 412
Denver, CO 80206
720-516-9403

Hospital Affiliation
  • University of Colorado Hospital
  • Veterans Affairs Medical Center
  • Denver Health Medical Center

Specialty Information

Specialties
  • Internal Medicine, Board Certification (2011)
  • General Cardiology, Board Certification (2014)
  • Cardiac Electrophysiology
Conditions & Treatments
  • Heart and Circulation - Arrhythmia
  • Heart and Circulation
Public Speaking
Yes

General Information

Medical Schools:
  • MD, Indiana University School of Medicine (2008)
Undergraduate Schools:
  • BS, Indiana University–Bloomington (IN) (2004)
Internships:
  • University of Colorado (2009)
Residency Programs:
  • University of Colorado, Internal Medicine (2011)
Fellowships:
  • University of Colorado, General Cardiology (2013)
  • University of Colorado, Cardiac Electrophysiology (2015)
Languages: English
Department: Medicine-Cardiology
SOM Resources
CU Resources
Contact Us
CU Anschutz
Fitzsimons Building
13001 East 17th Place
Campus Box C290
Aurora, CO 80045

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