Joseph Onyiah, MD
Associate Professor, Medicine-Gastroenterology
Medical School
- MD, Duke University School of Medicine (2007)
Residency
- Duke University Hospital Program, Internal Medicine (2010)
Fellowships
- University of North Carolina at Chapel Hill Program, Gastroenterology (2014)
Languages
EnglishDepartment
Medicine-GastroenterologyPublications
- Onyiah JC, Schaefer REM, Colgan SP. A Central Role for Heme Oxygenase-1 in the Control of Intestinal Epithelial Chemokine Expression. J Innate Immun. 2018;10(3):228-238. PubMed PMID: 29791903
- Cartwright, I.M., Curtis, V.F., Lanis, J.M. et al. Adaptation to inflammatory acidity through neutrophil-derived adenosine regulation of SLC26A3. Mucosal Immunol (2019) doi:10.1038/s41385-019-0237-2
- deZoeten EF, Battista KD, Colson SB, Lovell MA, Kessler BE, Isfort RW, Fennimore BP, Onyiah JC, Kao DJ, Yeckes A, Keely S, Murray M, Hoffenberg EJ, Colgan SP, Gerich ME. Markers of Hypoxia Correlate with Histologic and Endoscopic Severity of Colitis in Inflammatory Bowel Disease. Hypoxia (Auckl). 2020;8:1-12. PubMed PMID: 32104717
- Cartwright IM, Curtis VF, Lanis JM, Alexeev EE, Welch N, Goldberg MS, Schaefer REM, Gao RY, Chun C, Fennimore B, Onyiah JC, Gerich ME, Dempsey PJ, Colgan SP. Adaptation to inflammatory acidity through neutrophil-derived adenosine regulation of SLC26A3. Mucosal Immunol. 2020 Mar;13(2):230-244. PubMed PMID: 31792360
- Alexeev EE, Dowdell AS, Henen MA, Lanis JM, Lee JS, Cartwright IM, Schaefer REM, Ornelas A, Onyiah JC, Vögeli B, Colgan SP. Microbial-derived indoles inhibit neutrophil myeloperoxidase to diminish bystander tissue damage. FASEB J. 2021 May;35(5):e21552. PubMed PMID: 33826788
- Cartwright IM, Dowdell AS, Lanis JM, Brink KR, Mu A, Kostelecky RE, Schaefer REM, Welch N, Onyiah JC, Hall CHT, Gerich ME, Tabor JJ, Colgan SP. Mucosal acidosis elicits a unique molecular signature in epithelia and intestinal tissue mediated by GPR31-induced CREB phosphorylation. Proc Natl Acad Sci U S A. 2021 May 18;118(20). PubMed PMID: 33972436
- Schaefer REM, Callahan RC, Atif SM, Orlicky DJ, Cartwright IM, Fontenot AP, Colgan SP, Onyiah JC. Disruption of monocyte-macrophage differentiation and trafficking by a heme analog during active inflammation. Mucosal Immunol. 2021 Dec 16. [Epub ahead of print] PubMed PMID: 34916594
- Swei EC, Fox CM, Bowles DW, Rizeq MN, Onyiah JC. Use of Ruxolitinib for the Simultaneous Treatment of Severe Refractory Ulcerative Colitis and Polycythemia Vera. ACG Case Rep J. 2022 Jan;9(1):e00741. PubMed PMID: 35018293
- Schaefer REM, Callahan RC, Atif SM, Orlicky DJ, Cartwright IM, Fontenot AP, Colgan SP, Onyiah JC. Disruption of monocyte-macrophage differentiation and trafficking by a heme analog during active inflammation. Mucosal Immunol. 2022 Feb;15(2):244-256. PubMed PMID: 34916594
- Rella S, Onyiah J, Baker C, Singh V, Her A, Rasouli N. Design and rationale for the SIB trial: a randomized parallel comparison of semaglutide versus placebo on intestinal barrier function in type 2 diabetes mellitus. Ther Adv Endocrinol Metab. 2023 Oct 29;14:20420188231207348. doi: 10.1177/20420188231207348. PMID: 37916028; PMCID: PMC10617296.
- Loh L, Orlicky D, Spengler A, Levens C, Celli S, Domenico J, Klarquist J, Onyiah J, Matsuda J, Kuhn K, Gapin L. MAIT cells drive chronic inflammation in a genetically diverse murine model of spontaneous colitis. bioRxiv [Preprint]. 2023 Dec 1:2023.11.29.569225. doi: 10.1101/2023.11.29.569225. PMID: 38076996; PMCID: PMC10705467.
- Alula KM, Delgado-Deida Y, Callahan R, Till A, Underwood L, Thompson WE, Souza RF, Dassopoulos T, Onyiah J, Venuprasad K, Theiss AL. Inner mitochondrial membrane protein Prohibitin 1 mediates Nix-induced, Parkin-independent mitophagy. Sci Rep. 2023 Jan 2;13(1):18. doi: 10.1038/s41598-022-26775-x. PMID: 36593241; PMCID: PMC9807637.
Professional Memberships
- American Gastroenterological Association (AGA), Member
Practice Locations
Denver Veterans Affairs Medical Center1055 Clermont St
Denver, CO 80220
1-888-336-8262
Hospital Affiliation
- University of Colorado Hospital
- Veterans Affairs Medical Center
Specialty Information
Specialties- Gastroenterology, Board Certification
- Internal Medicine, Board Certification