Neurohospitalist medicine, neuro-infectious and emerging infectious diseases, public health and epidemiology, outbreak investigation and control, emergency preparedness and response, environmental health and toxicology, climate and health, public policy, communication, and education
Teaching
Neuro-infectious Diseases and Autoimmune Neurology Fellowship Director
(2015)
School of Medicine,
Neurology
Global Neurology Education Director
(2019)
School of Medicine,
Neurology
Publications
Ardakani R, Chauhan L, Piquet AL, Tyler KL, Pastula DM. An Overview of Saint Louis Encephalitis. Neurohospitalist. 2024 Apr;14(2):230-231. PubMed PMID: 38666278
Jellins TS, Borko TL, Otero-Bell R, Arnett K, Saunders S, Poisson SN, Orjuela KD, Salehi Omran S, Jones WJ, Leppert M, Madera A, Carlson A, Pastula DM, Sauer BM, Piquet AL, Gonzales NR. Diversity, equity, and inclusion (DEI) in medical education: DEI at the bedside. J Neurol Sci. 2024 Apr 15;459:122946. PubMed PMID: 38493733
Roberts JA, Kapadia RK, Pastula DM, Thakur KT. Public health trends in neurologically relevant infections: a global perspective. Ther Adv Infect Dis. 2024 Jan-Dec;11:20499361241274206. PubMed PMID: 39301451
Borko TL, Baxter R, Cabrera-Martinez B, Thiruppathi E, Sabalza M, Venkataraman I, Selva S, Rester C, Sillau S, Pastula DM, Bennett JL, Alvarez E, Gross R, Shah A, Kammeyer R, Corboy JR, Kedl RM, Hsieh EWY, Piquet AL. SARS-CoV-2 mRNA vaccination induces an antigen-specific T cell response correlating with plasma interferon-gamma in B cell depleted patients. J Neuroimmunol. 2023 Aug 29;383:578192. [Epub ahead of print] PubMed PMID: 37666038
Wolf AB, Money KM, Chandnani A, Daley CL, Griffith DE, Chauhan L, Coffman N, Piquet AL, Tyler KL, Zimmer SM, Montague BT, Mann S, Pastula DM. Mycobacterium abscessus Meningitis Associated with Stem Cell Treatment During Medical Tourism. Emerg Infect Dis. 2023 Aug;29(8):1655-1658. PubMed PMID: 37486227
Money KM, Chauhan L, Piquet AL, Tyler KL, Pastula DM. An Overview of Japanese Encephalitis. Neurohospitalist. 2023 Jul;13(3):328-330. PubMed PMID: 37441216
Kobau R, Luncheon C, Pastula DM, Greenlund KJ. COVID-19 vaccination status and related process of care outcomes among U.S. adults with active epilepsy-National Health Interview Survey, United States, 2021. Epilepsy Behav. 2023 Jun;143:109223. PubMed PMID: 37119577
Money KM, Kitani T, Pastula DM. Reply to "MOG-IgG-Associated Bilateral Optic Neuritis in Temporal Relation to Monkeypox Vaccination". Ann Neurol. 2023 Jun;93(6):1217-1218. PubMed PMID: 37038280
Money KM, Barnett TA, Rapaka S, Osborn R, Kitani T, Fuguet D, Amjad F, Clark JR, Chakravarty D, Copeland MJ, Honce JM, Kumar PN, Kumar RN, Mousa-Ibrahim F, Sirdar B, Sobota R, Tang M, Bolon MK, Russell EJ, Wilson M, Tornatore C, Batra A, Tyler KL, Pastula DM. Monkeypox-Associated Central Nervous System Disease: A Case Series and Review. Ann Neurol. 2023 May;93(5):893-905. PubMed PMID: 36602053
Kapadia RK, Staples JE, Gill CM, Fischer M, Khan E, Laven JJ, Panella A, Velez JO, Hughes HR, Brault A, Pastula DM, Gould CV. Severe Arboviral Neuroinvasive Disease in Patients on Rituximab Therapy: A Review. Clin Infect Dis. 2023 Mar 21;76(6):1142-1148. PubMed PMID: 36103602
Wilson N, Vahey GM, McDonald E, Fitzpatrick K, Lehman J, Clark S, Lindell K, Pastula DM, Perez S, Rhodes H, Gould CV, Staples JE, Martin SW, Cervantes K. Tick bite risk factors and prevention measures in an area with emerging Powassan virus disease. Public Health Chall. 2023 Dec;2(4). PubMed PMID: 38800642
Lowe MC, Money KM, Matthews E, Pastula DM, Piquet AL. case of autoimmune GFAP astrocytopathy with eosinophils in the cerebrospinal fluid. J Neuroimmunol. 2023 Dec 15;385:578249. PubMed PMID: 37992587
Borko TL, Baxter R, Cabrera-Martinez B, Thiruppathi E, Sabalza M, Venkataraman I, Selva S, Rester C, Sillau S, Pastula DM, Bennett JL, Alvarez E, Gross R, Shah A, Kammeyer R, Corboy JR, Kedl RM, Hsieh EWY, Piquet AL. SARS-CoV-2 mRNA vaccination induces an antigen-specific T cell response correlating with plasma interferon-gamma in B cell depleted patients. J Neuroimmunol. 2023 Oct 15;383:578192. PubMed PMID: 37666038
Chauhan L, Matthews E, Piquet AL, Henao-Martinez A, Franco-Paredes C, Tyler KL, Beckham D, Pastula DM. Nervous System Manifestations of Arboviral Infections. Curr Trop Med Rep. 2022 Sep 15;:1-12. [Epub ahead of print] PubMed PMID: 36124288
Pastula DM, Tyler KL. An Overview of Monkeypox Virus and Its Neuroinvasive Potential. Ann Neurol. 2022 Oct;92(4):527-531. PubMed PMID: 35932225
Matthews E, Chauhan L, Piquet AL, Tyler KL, Pastula DM. An Overview of La Crosse Virus Disease. Neurohospitalist. 2022 Jul;12(3):587-588. PubMed PMID: 35755222
Sapkota S, Caruso E, Kobau R, Radhakrishnan L, Jobst B, DeVies J, Tian N, Hogan RE, Zack MM, Pastula DM. Seizure- or Epilepsy-Related Emergency Department Visits Before and During the COVID-19 Pandemic - United States, 2019-2021. MMWR Morb Mortal Wkly Rep. 2022 May 27;71(21):703-708. PubMed PMID: 35617146
Kapadia RK, Staples JE, Gill CM, Fischer M, Khan E, Laven JJ, Panella A, Velez JO, Hughes HR, Brault A, Pastula DM, Gould CV. Severe Arboviral Neuroinvasive Disease in Patients on Rituximab Therapy: A Review. Clin Infect Dis. 2022 Sep 14. [Epub ahead of print] PubMed PMID: 36103602
Vahey GM, Wilson N, McDonald E, Fitzpatrick K, Lehman J, Clark S, Lindell K, Pastula DM, Perez S, Rhodes H, Gould CV, Staples JE, Cervantes K, Martin SW. Seroprevalence of Powassan Virus Infection in an Area Experiencing a Cluster of Disease Cases: Sussex County, New Jersey, 2019. Open Forum Infect Dis. 2022 Mar;9(3):ofac023. PubMed PMID: 35169592
Pastula DM, Copeland MJ, Hannan MC, Rapaka S, Kitani T, Kleiner E, Showler A, Yuen C, Ferriman EM, House J, O'Brien S, Burakoff A, Gupta B, Money KM, Matthews E, Beckham JD, Chauhan L, Piquet AL, Kumar RN, Tornatore CS, Padgett K, O'Laughlin K, Mangla AT, Kumar PN, Tyler KL, O'Connor SM. Two Cases of Monkeypox-Associated Encephalomyelitis - Colorado and the District of Columbia, July-August 2022. MMWR Morb Mortal Wkly Rep. 2022 Sep 23;71(38):1212-1215. PubMed PMID: 36136957
Gill CM, Kapadia RK, Beckham JD, Piquet AL, Tyler KL, Pastula DM. Usutu virus disease: a potential problem for North America?. J Neurovirol. 2020 Apr;26(2):149-154. PubMed PMID: 31858483
Macchi ZA, Kleinschmidt-DeMasters BK, Orjuela KD, Pastula DM, Piquet AL, Baca CB. Glioblastoma as an autoimmune limbic encephalitis mimic: A case and review of the literature. J Neuroimmunol. 2020 Mar 7;342:577214. [Epub ahead of print] PubMed PMID: 32182452
Kapadia RK, Ney DE, Hannan M, Farley M, Pastula DM, Piquet AL. Glial fibrillary acidic protein (GFAP) associated autoimmune meningoencephalitis in a patient receiving nivolumab. J Neuroimmunol. 2020 Jul 15;344:577259. PubMed PMID: 32416558
Staples JE, Pastula DM, Panella AJ, Rabe IB, Kosoy OI, Walker WL, Velez JO, Lambert AJ, Fischer M. Investigation of Heartland Virus Disease Throughout the United States, 2013-2017. Open Forum Infect Dis. 2020 May;7(5):ofaa125. PubMed PMID: 32478118
Gill CM, Beckham JD, Piquet AL, Tyler KL, Pastula DM. Five Emerging Neuroinvasive Arboviral Diseases: Cache Valley, Eastern Equine Encephalitis, Jamestown Canyon, Powassan, and Usutu. Semin Neurol. 2019 Aug;39(4):419-427. PubMed PMID: 31533182
Sapkota S, Kobau R, Pastula DM, Zack MM. Close to 1 million US adults aged 55?years or older have active epilepsy-National Health Interview Survey, 2010, 2013, and 2015. Epilepsy Behav. 2018 Aug 2. [Epub ahead of print] PubMed PMID: 30078516
Carlson AL, Pastula DM, Lambert AJ, Staples JE, Muehlenbachs A, Turabelidze G, Eby CS, Keller J, Hess B, Buller RS, Storch GA, Byrnes K, Dehner L, Kirmani N, Kuhlmann FM. Heartland Virus and Hemophagocytic Lymphohistiocytosis in Immunocompromised Patient, Missouri, USA. Emerg Infect Dis. 2018 May;24(5):893-897. PubMed PMID: 29664369
Pessoa A, van der Linden V, Yeargin-Allsopp M, Carvalho MDCG, Ribeiro EM, Van Naarden Braun K, Durkin MS, Pastula DM, Moore JT, Moore CA. Motor Abnormalities and Epilepsy in Infants and Children With Evidence of Congenital Zika Virus Infection. Pediatrics. 2018 Feb;141(Suppl 2):S167-S179. PubMed PMID: 29437050
Ludt C, Leppert M, Jones A, Song J, Kuwayama D, Pastula DM, Poisson S. Multiple Strokes Associated With Elongation of the Hyoid Bone. Neurohospitalist. 2018 Jan;8(1):35-37. PubMed PMID: 29276562
Sapkota S, Kobau R, Pastula DM, Zack MM. People with epilepsy are diagnosed most often with unspecified epilepsy, followed by focal epilepsy, generalized convulsive epilepsy, and generalized nonconvulsive epilepsy-US MarketScan data, 2010-2015. Epilepsy Behav. 2018 Feb;79:244-246. PubMed PMID: 29249447
Beattie J, Parajuli S, Sanger M, Lee G, Pleninger P, Crowley G, Kwon S, Murthy V, Manko JA, Caplan A, Dufort E, Pastula DM, Nolan A. Zika Virus-Associated Guillain-Barré Syndrome in a Returning US Traveler. Infect Dis Clin Pract (Baltim Md). 2018 Nov;26(6):e80-e84. PubMed PMID: 30923438
McKay SL, Lee AD, Lopez AS, Nix WA, Dooling KL, Keaton AA, Spence-Davizon E, Herlihy R, Clark TA, Hopkins SE, Pastula DM, Sejvar J, Oberste MS, Pallansch MA, Patel M, Routh JA. Increase in Acute Flaccid Myelitis - United States, 2018. MMWR Morb Mortal Wkly Rep. 2018 Nov 16;67(45):1273-1275. PubMed PMID: 30439867
McGuinness I, Beckham JD, Tyler KL, Pastula DM. An Overview of Yellow Fever Virus Disease. Neurohospitalist. 2017 Oct;7(4):157-158. PubMed PMID: 28974992
Salinas JL, Major CG, Pastula DM, Dirlikov E, Styczynski A, Luciano CA, Wojna V, Sharp TM, Sejvar JJ, Rivera-Garcia B. Incidence and clinical characteristics of Guillain-Barré syndrome before the introduction of Zika virus in Puerto Rico. J Neurol Sci. 2017 Jun 15;377:102-106. PubMed PMID: 28477675
Pastula DM, Durrant JC, Smith DE, Beckham JD, Tyler KL. Zika Virus Disease for the Neurointensivist. Neurocrit Care. 2017 Jun;26(3):457-463. PubMed PMID: 27995511
Tyler KL, Pastula DM. Hepatitis E Virus and Guillain-Barré Syndrome. JAMA Neurol. 2017 Jan 1;74(1):13-15. PubMed PMID: 27820625
Dirlikov E, Kniss K, Major C, Thomas D, Virgen CA, Mayshack M, Asher J, Mier-Y-Teran-Romero L, Salinas JL, Pastula DM, Sharp TM, Sejvar J, Johansson MA, Rivera-Garcia B. Guillain-Barré Syndrome and Healthcare Needs during Zika Virus Transmission, Puerto Rico, 2016. Emerg Infect Dis. 2017 Jan;23(1):134-136. PubMed PMID: 27779466
Hennessey MJ, Pastula DM, Machesky K, Fischer M, Lindsey NP, DiOrio M, Staples JE, de Fijter S. Investigation of Acute Flaccid Paralysis Reported with La Crosse Virus Infection, Ohio, USA, 2008-2014. Emerg Infect Dis. 2017 Dec;23(12):2075-2077. PubMed PMID: 29148398
Pastula DM, Hancock WT, Bel M, Biggs H, Marfel M, Lanciotti R, Laven J, Chen TH, Staples JE, Fischer M, Hills SL. Chikungunya virus disease outbreak in Yap State, Federated States of Micronesia. PLoS Negl Trop Dis. 2017 Mar;11(3):e0005410. PubMed PMID: 28248978
Pastula DM, Yeargin-Allsopp M, Kobau R. Enhanced Epilepsy Surveillance and Awareness in the Age of Zika. JAMA Neurol. 2017 Jun 1;74(6):631-632. PubMed PMID: 28418503
McGuinness I, Beckham JD, Tyler KL, Pastula DM. An Overview of Yellow Fever Virus Disease. Neurohospitalist. 2017 Oct;7(4):157-158. PubMed PMID: 28974992
Dirlikov E, Major CG, Mayshack M, Medina N, Matos D, Ryff KR, Torres-Aponte J, Alkis R, Munoz-Jordan J, Colon-Sanchez C, Salinas JL, Pastula DM, Garcia M, Segarra MO, Malave G, Thomas DL, Rodríguez-Vega GM, Luciano CA, Sejvar J, Sharp TM, Rivera-Garcia B. Guillain-Barré Syndrome During Ongoing Zika Virus Transmission - Puerto Rico, January 1-July 31, 2016. MMWR Morb Mortal Wkly Rep. 2016 Sep 2;65(34):910-4. PubMed PMID: 27584942
Aliabadi N, Messacar K, Pastula DM, Robinson CC, Leshem E, Sejvar JJ, Nix WA, Oberste MS, Feikin DR, Dominguez SR. Enterovirus D68 Infection in Children with Acute Flaccid Myelitis, Colorado, USA, 2014. Emerg Infect Dis. 2016 Aug;22(8):1387-94. PubMed PMID: 27434186
Sharp TM, Muñoz-Jordán J, Perez-Padilla J, Bello-Pagán MI, Rivera A, Pastula DM, Salinas JL, Martínez Mendez JH, Méndez M, Powers AM, Waterman S, Rivera-García B. Zika Virus Infection Associated With Severe Thrombocytopenia. Clin Infect Dis. 2016 Nov 1;63(9):1198-1201. PubMed PMID: 27418575
Pastula DM, Smith DE, Beckham JD, Tyler KL. An Overview of Zika Virus Disease. Neurohospitalist. 2016 Jul;6(3):93-4. PubMed PMID: 27366289
Sejvar JJ, Lopez AS, Cortese MM, Leshem E, Pastula DM, Miller L, Glaser C, Kambhampati A, Shioda K, Aliabadi N, Fischer M, Gregoricus N, Lanciotti R, Nix WA, Sakthivel SK, Schmid DS, Seward JF, Tong S, Oberste MS, Pallansch M, Feikin D. Acute Flaccid Myelitis in the United States, August-December 2014: Results of Nationwide Surveillance. Clin Infect Dis. 2016 Sep 15;63(6):737-45. PubMed PMID: 27318332
Pastula DM, Smith DE, Beckham JD, Tyler KL. Four emerging arboviral diseases in North America: Jamestown Canyon, Powassan, chikungunya, and Zika virus diseases. J Neurovirol. 2016 Jun;22(3):257-60. PubMed PMID: 26903031
Beckham JD, Pastula DM, Massey A, Tyler KL. Zika Virus as an Emerging Global Pathogen: Neurological Complications of Zika Virus. JAMA Neurol. 2016 Jul 1;73(7):875-9. PubMed PMID: 27183312
Pastula DM, Durrant JC, Smith DE, Beckham JD, Tyler KL. Zika Virus Disease for the Neurointensivist. Neurocrit Care. 2016 Dec 19. [Epub ahead of print] PubMed PMID: 27995511
Smith DE, Beckham JD, Tyler KL, Pastula DM. Zika virus disease for neurologists. Neurol Clin Pract. 2016 Dec;6(6):515-522. PubMed PMID: 28058206
Forrester JD, Kugeler KJ, Perea AE, Pastula DM, Mead PS. No Geographic Correlation between Lyme Disease and Death Due to 4 Neurodegenerative Disorders, United States, 2001-2010. Emerg Infect Dis. 2015 Nov;21(11):2036-9. PubMed PMID: 26488307
Pastula DM, Burish M, Reis GF, Bollen A, Cha S, Ralph J, Douglas VC. Adult-onset central nervous system hemophagocytic lymphohistiocytosis: a case report. BMC Neurol. 2015 Oct 14;15:203. PubMed PMID: 26467435
Pastula DM, Burish M, Reis GF, Bollen A, Cha S, Ralph J, Douglas VC. Adult-onset central nervous system hemophagocytic lymphohistiocytosis: a case report. BMC Neurol. 2015 Oct 14;15:203. PubMed PMID: 26467435
Pastula DM, Hoang Johnson DK, White JL, Dupuis AP 2nd, Fischer M, Staples JE. Jamestown Canyon Virus Disease in the United States-2000-2013. Am J Trop Med Hyg. 2015 Aug;93(2):384-9. PubMed PMID: 26033022
Pastula DM, Aliabadi N, Haynes AK, Messacar K, Schreiner T, Maloney J, Dominguez SR, Davizon ES, Leshem E, Fischer M, Nix WA, Oberste MS, Seward J, Feikin D, Miller L. Acute neurologic illness of unknown etiology in children - Colorado, August-September 2014. MMWR Morb Mortal Wkly Rep. 2014 Oct 10;63(40):901-2. PubMed PMID: 25299607
Pastula DM, Turabelidze G, Yates KF, Jones TF, Lambert AJ, Panella AJ, Kosoy OI, Velez JO, Fisher M, Staples E. Notes from the field: Heartland virus disease - United States, 2012-2013. MMWR Morb Mortal Wkly Rep. 2014 Mar 28;63(12):270-1. PubMed PMID: 24670929
Pastula DM, Moore DH, Bedlack RS. Creatine for amyotrophic lateral sclerosis/motor neuron disease. Cochrane Database Syst Rev. 2012 Dec 12;12:CD005225. PubMed PMID: 23235621
Pastula DM, Coffman CJ, Allen KD, Oddone EZ, Kasarskis EJ, Lindquist JH, Morgenlander JC, Norman BB, Rozear MP, Sams LA, Sabet A, Bedlack RS. Factors associated with survival in the National Registry of Veterans with ALS. Amyotroph Lateral Scler. 2009 Oct-Dec;10(5-6):332-8. PubMed PMID: 19922120
Bedlack RS, Pastula DM, Hawes J, Heydt D. Open-label pilot trial of levetiracetam for cramps and spasticity in patients with motor neuron disease. Amyotroph Lateral Scler. 2009 Aug;10(4):210-5. PubMed PMID: 18821142
Bedlack RS, Pastula DM, Welsh E, Pulley D, Cudkowicz ME. Scrutinizing enrollment in ALS clinical trials: room for improvement?. Amyotroph Lateral Scler. 2008 Oct;9(5):257-65. PubMed PMID: 18608092