Daniel Kao, MD

Publications

• Saeedi BJ, Kao DJ, Kitzenberg DA, Dobrinskikh E, Schwisow KD, Masterson JC, Kendrick AA, Kelly CJ, Bayless AJ, Kominsky DJ, Campbell EL, Kuhn KA, Furuta GT, Colgan SP, Glover LE. HIF-dependent regulation of claudin-1 is central to intestinal epithelial tight junction integrity. Mol Biol Cell. 2015 Jun 15;26(12):2252-62. PubMed PMID: 25904334
• Lanis JM, Alexeev EE, Curtis VF, Kitzenberg DA, Kao DJ, Battista KD, Gerich ME, Glover LE, Kominsky DJ, Colgan SP. Tryptophan metabolite activation of the aryl hydrocarbon receptor regulates IL-10 receptor expression on intestinal epithelia. Mucosal Immunol. 2017 Jan 18. [Epub ahead of print] PubMed PMID: 28098246
• Campbell EL, Kao DJ, Colgan SP. Neutrophils and the inflammatory tissue microenvironment in the mucosa. Immunol Rev. 2016 Sep;273(1):112-20. PubMed PMID: 27558331
• Kao DJ, Lanis JM, Alexeev E, Kominsky DJ. HPLC-Based Metabolomic Analysis of Normal and Inflamed Gut. Methods Mol Biol. 2016;1422:63-75. PubMed PMID: 27246023
• Kao DJ, Lanis JM, Alexeev E, Kominsky DJ. NMR-Based Metabolomic Analysis of Normal and Inflamed Gut. Methods Mol Biol. 2016;1422:77-87. PubMed PMID: 27246024
• Curtis VF, Cartwright IM, Lee JS, Wang RX, Kao DJ, Lanis JM, Burney KM, Welch N, Hall CHT, Goldberg MS, Campbell EL, Colgan SP. Neutrophils as sources of dinucleotide polyphosphates and metabolism by epithelial ENPP1 to influence barrier function via adenosine signaling. Mol Biol Cell. 2018 Nov 1;29(22):2687-2699. PubMed PMID: 30188771
• Alexeev EE, Lanis JM, Kao DJ, Campbell EL, Kelly CJ, Battista KD, Gerich ME, Jenkins BR, Walk ST, Kominsky DJ, Colgan SP. Microbiota-Derived Indole Metabolites Promote Human and Murine Intestinal Homeostasis through Regulation of Interleukin-10 Receptor. Am J Pathol. 2018 May;188(5):1183-1194. PubMed PMID: 29454749
• Leinwand KL, Jones AA, Huang RH, Jedlicka P, Kao DJ, de Zoeten EF, Ghosh S, Moaddel R, Wehkamp J, Ostaff MJ, Bader J, Aherne CM, Collins CB. Cannabinoid Receptor-2 Ameliorates Inflammation in Murine Model of Crohn's Disease. J Crohns Colitis. 2017 Oct 27;11(11):1369-1380. PubMed PMID: 28981653
• Kao DJ, Saeedi BJ, Kitzenberg D, Burney KM, Dobrinskikh E, Battista KD, Vázquez-Torres A, Colgan SP, Kominsky DJ. 2017. Intestinal epithelial ecto-5'-nucleotidase (CD73) regulates intestinal colonization and infection by nontyphoidal Salmonella. Infect Immun 85:e01022-16. https://doi.org/10.1128/IAI.01022-16.
• Lanis JM, Kao DJ, Alexeev EE, Colgan SP. Tissue metabolism and the inflammatory bowel diseases. J Mol Med (Berl). 2017 Sep;95(9):905-913. PubMed PMID: 28528514
• Lanis, J.M., Kao, D.J., Alexeev, E.E. et al. J Mol Med (2017) 95: 905. https://doi.org/10.1007/s00109-017-1544-2
• Lanis JM, Alexeev EE, Curtis VF, et al. Tryptophan Metabolite Activation of the Aryl Hydrocarbon Receptor Regulates IL10 Receptor Expression on Intestinal Epithelia. Mucosal immunology. 2017;10(5):1133-1144. doi:10.1038/mi.2016.133.
• Alexeev EE, Lanis JM , Kao DJ, Campbell EL, Kelly CJ, Battista KD, Gerich ME, Jenkins BR, Walk ST, Kominsky DJ, Colgan SP. Microbiota-derived indole metabolites promote human and murine intestinal homeostasis through regulation of interleukin-10 receptor. Am J Pathol. In press
• Campbell EL, Kao DJ, Colgan SP. Neutrophils and the Inflammatory Tissue Microenvironment in the Mucosa. Immunological reviews. 2016;273(1):112-120. doi:10.1111/imr.12456.
• deZoeten EF, Battista KD, Colson SB, Lovell MA, Kessler BE, Isfort RW, Fennimore BP, Onyiah JC, Kao DJ, Yeckes A, Keely S, Murray M, Hoffenberg EJ, Colgan SP, Gerich ME. Markers of Hypoxia Correlate with Histologic and Endoscopic Severity of Colitis in Inflammatory Bowel Disease. Hypoxia (Auckl). 2020;8:1-12. PubMed PMID: 32104717
• Alexeev EE, Lanis JM, Kao DJ, Campbell EL, Kelly CJ, Battista KD, Gerich ME, Jenkins BR, Walk ST, Kominsky DJ, Colgan SP. Microbiota-Derived Indole Metabolites Promote Human and Murine Intestinal Homeostasis through Regulation of Interleukin-10 Receptor. Am J Pathol. 2018 May;188(5):1183-1194. PubMed PMID: 29454749
• Kitzenberg DA, Lee JS, Mills KB, Kim JS, Liu L, Vázquez-Torres A, Colgan SP, Kao DJ. Adenosine Awakens Metabolism to Enhance Growth-Independent Killing of Tolerant and Persister Bacteria across Multiple Classes of Antibiotics. mBio. 2022 Jun 28;13(3):e0048022. PubMed PMID: 35575513
• Thompson NT, Kitzenberg DA, Kao DJ. Persister-mediated emergence of antimicrobial resistance in agriculture due to antibiotic growth promoters. AIMS Microbiol. 2023;9(4):738-756. PubMed PMID: 38173975

Practice Locations

UCHealth Digestive Health Center - Anschutz Medical Campus
1635 Aurora Ct
5th Floor
Aurora, CO 80045
720-848-2777

Specialty Information

Specialties

• Gastroenterology, Board Certification