Laura Sherlock, MD

Publications

• Wright CJ, Sherlock LG, Sahni R, Polin RA. Preventing Continuous Positive Airway Pressure Failure: Evidence-Based and Physiologically Sound Practices from Delivery Room to the Neonatal Intensive Care Unit. Clin Perinatol. 2018 Jun;45(2):257-271. PubMed PMID: 29747887
• McGraw MD, Sherlock LG, Bailey KL, Abman SH. Developmental Origins of Chronic Lung Diseases. Mechanical Stretch, Micro-RNAs, and Hydrogels. Am J Respir Cell Mol Biol. 2018 Aug;59(2):267-270. PubMed PMID: 29641225
• Sherlock LG, Trumpie A, Hernandez-Lagunas L, McKenna S, Fisher S, Bowler R, Wright CJ, Delaney C, Nozik-Grayck E. Redistribution of Extracellular Superoxide Dismutase Causes Neonatal Pulmonary Vascular Remodeling and PH but Protects Against Experimental Bronchopulmonary Dysplasia. Antioxidants (Basel). 2018 Mar 14;7(3). PubMed PMID: 29538340
• Delaney C, Sherlock L, Fisher S, Maltzahn J, Wright C, Nozik-Grayck E. Serotonin 2A receptor inhibition protects against the development of pulmonary hypertension and pulmonary vascular remodeling in neonatal mice. Am J Physiol Lung Cell Mol Physiol. 2018 May 1;314(5):L871-L881. PubMed PMID: 29345193
• Sherlock LG, Wright CJ, Kinsella JP, Delaney C. Inhaled nitric oxide use in neonates: Balancing what is evidence-based and what is physiologically sound. Nitric Oxide. 2020 Feb 1;95:12-16. PubMed PMID: 31866361
• White A, Mukherjee P, Stremming J, Sherlock LG, Reynolds RM, Smith D, Asturias EJ, Grover TR, Dietz RM. Neonates Hospitalized with Community-Acquired SARS-CoV-2 in a Colorado Neonatal Intensive Care Unit. Neonatology. 2020 Jun 4;:1-5. [Epub ahead of print] PubMed PMID: 32498065
• Sherlock LG, Sjostrom K, Sian L, Delaney C, Tipple TE, Krebs NF, Nozik-Grayck E, Wright CJ. Hepatic-Specific Decrease in the Expression of Selenoenzymes and Factors Essential for Selenium Processing After Endotoxemia. Front Immunol. 2020;11:595282. PubMed PMID: 33224150
• Dobrinskikh E, Sherlock LG, Orlicky DJ, Zheng L, De Dios R, Balasubramaniyan D, Sizemore T, Butler B, Wright CJ. The developing murine lung is susceptible to acetaminophen toxicity. Am J Physiol Lung Cell Mol Physiol. 2021 May 1;320(5):L969-L978. PubMed PMID: 33759579
• Dobrinskikh E, Al-Juboori S, Zarate M, Zheng L, de Dios R, Balasubramaniyan D, Sherlock LG, Orlicky D, Wright CJ. Pulmonary implications of acetaminophen exposures independent of hepatic toxicity. Am J Physiol Lung Cell Mol Physiol. 2021 Sep 29. [Epub ahead of print] PubMed PMID: 34585971
• Sherlock LG, Balasubramaniyan D, Zheng L, Zarate M, Sizemore T, Delaney C, Tipple TE, Wright CJ, Nozik-Grayck E. Neonatal Selenoenzyme Expression Is Variably Susceptible to Duration of Maternal Selenium Deficiency. Antioxidants (Basel). 2021 Feb 14;10(2). PubMed PMID: 33672905
• Zarate MA, De Dios RK, Balasubramaniyan D, Zheng L, Sherlock LG, Rozance PJ, Wright CJ. The Acute Hepatic NF-?B-Mediated Proinflammatory Response to Endotoxemia Is Attenuated in Intrauterine Growth-Restricted Newborn Mice. Front Immunol. 2021;12:706774. PubMed PMID: 34539638
• McCulley DJ, Jensen EA, Sucre JMS, McKenna S, Sherlock LG, Dobrinskikh E, Wright CJ. Racing against time: leveraging preclinical models to understand pulmonary susceptibility to perinatal acetaminophen exposures. Am J Physiol Lung Cell Mol Physiol. 2022 Jul 1;323(1):L1-L13. PubMed PMID: 35503238
• Sherlock LG, Balasubramaniyan D, Zheng L, Grayck M, McCarthy WC, De Dios RC, Zarate MA, Orlicky DJ, De Dios R, Wright CJ. APAP-Induced I?Bß/NF?B Signaling Drives Hepatic Il6 Expression and Associated Sinusoidal Dilation. Toxicol Sci. 2022 Jan 24;185(2):158-169. PubMed PMID: 34726736
• Roberts DS, Sherlock LG, Posey JN, Archambault JL, Nozik ES, Delaney CA. Serotonin-deficient neonatal mice are not protected against the development of experimental bronchopulmonary dysplasia or pulmonary hypertension. Physiol Rep. 2022 Oct;10(19):e15482. PubMed PMID: 36200294
• Solar M, Grayck MR, McCarthy WC, Zheng L, Lacayo OA, Sherlock LG, Zhou R, Orlicky DJ, Wright CJ. Absence of I?Bß/NF?B signaling does not attenuate acetaminophen-induced hepatic injury. Anat Rec (Hoboken). 2022 Nov 25. [Epub ahead of print] PubMed PMID: 36426684
• Sherlock LG, Krebs NF. Small and mighty: Micronutrients at the intersection of neonatal immunity and infection. Neoreviews
• Sherlock LG et al. Neonatal selenium deficiency decreases selenoproteins in the lung and impairs pulmonary alveolar development. Antioxidants
• Pharmacology in Neonatal Care
• Cookson MW, Sherlock LG. Sex differences in endothelial cell function: an evolving explanation of sex differences in preterm infant pulmonary outcomes. Am J Physiol Heart Circ Physiol. 2023 May 1;324(5):H579-H580. PubMed PMID: 36897750
• Sherlock LG, Krebs NF. Small and Mighty: Micronutrients at the Intersection of Neonatal Immunity and Infection. Neoreviews. 2023 Mar 1;24(3):e158-e174. PubMed PMID: 36854844
• McCarthy WC, Sherlock LG, Grayck MR, Zheng L, Lacayo OA, Solar M, Orlicky DJ, Dobrinskikh E, Wright CJ. Innate Immune Zonation in the Liver: NF-?B (p50) Activation and C-Reactive Protein Expression in Response to Endotoxemia Are Zone Specific. J Immunol. 2023 May 1;210(9):1372-1385. PubMed PMID: 36946778
• Bailey-Downs LC, Sherlock LG, Crossley MN, Rivera Negron A, Pierce PT, Wang S, Zhong H, Carter C, Burge K, Eckert JV, Rogers LK, Vitiello PF, Tipple TE. Selenium Deficiency Exacerbates Hyperoxia-Induced Lung Injury in Newborn C3H/HeN Mice. Antioxidants (Basel). 2024 Mar 25;13(4). PubMed PMID: 38671839
• Grayck MR, McCarthy WC, Solar M, Golden E, Balasubramaniyan N, Zheng L, Sherlock LG, Wright CJ. GSK3ß/NF-?B -dependent transcriptional regulation of homeostatic hepatocyte Tnf production. Am J Physiol Gastrointest Liver Physiol. 2024 Apr 1;326(4):G374-G384. PubMed PMID: 38193163
• McCarthy WC, Sherlock LG, Grayck MR, Zheng L, Lacayo OA, Solar M, Orlicky DJ, Dobrinskikh E, Wright CJ. Innate Immune Zonation in the Liver: NF-?B (p50) Activation and C-Reactive Protein Expression in Response to Endotoxemia Are Zone Specific. J Immunol. 2023 May 1;210(9):1372-1385. PubMed PMID: 36946778
• Cookson MW, Sherlock LG. Sex differences in endothelial cell function: an evolving explanation of sex differences in preterm infant pulmonary outcomes. Am J Physiol Heart Circ Physiol. 2023 May 1;324(5):H579-H580. PubMed PMID: 36897750
• Sherlock LG, Krebs NF. Small and Mighty: Micronutrients at the Intersection of Neonatal Immunity and Infection. Neoreviews. 2023 Mar 1;24(3):e158-e174. PubMed PMID: 36854844

Practice Locations

Children's Hospital Colorado Anschutz Medical Campus
13123 East 16th Ave
Aurora, CO 80045
720-777-1234

Hospital Affiliation

• Children's Hospital Colorado

Specialty Information

Specialties

• Neonatal-Perinatal Medicine