Christopher Ng, MD
Assistant Professor, Pediatrics-Heme/Onc and Bone Marrow Transplantation

Publications

• Koukouritaki SB, Thinn AMM, Ashworth KJ, Fang J, Slater HS, Du LM, Nguyen HTT, Pillois X, Nurden AT, Ng CJ, Di Paola J, Zhu J, Wilcox DA. A single F153Sß3 mutation causes constitutive integrin aIIbß3 activation in a variant form of Glanzmann thrombasthenia. Blood Adv. 2023 Jul 11;7(13):3180-3191. PubMed PMID: 36884296
• Ng CJ, Liu A, Venkataraman S, Ashworth KJ, Baker CD, O'Rourke R, Vibhakar R, Jones KL, Di Paola J. Single-cell transcriptional analysis of human endothelial colony-forming cells from patients with low VWF levels. Blood. 2022 Apr 7;139(14):2240-2251. PubMed PMID: 35143643
• Woods GM, Raffini L, Brandão LR, Jaffray J, Branchford BR, Ng CJ, Sartain SE, Pak J, Male C, Zia A, Rizzi M, Sirachainan N, Faustino EVS, Carpenter SL, Goldenberg NA. Practical considerations and consensus opinion for children's hospital-based inpatient hemostasis and thrombosis (HAT) consultative services: Communication from the ISTH SSC Subcommittee on Pediatric/Neonatal Thrombosis and Hemostasis. J Thromb Haemost. 2022 Sep;20(9):2151-2158. PubMed PMID: 35748322
• Liu A, Ng CJ. Quantitative analysis of Weibel-Palade bodies. PLoS One. 2022;17(12):e0278044. PubMed PMID: 36542620
• Ng CJ, Spomer N, Shearer R, LeBlanc A, Funk S, Manco-Johnson M, Branchford B, Warren B, Buckner TW, Cowell A, Moyer G, Wang M, Gibson E, Mashburn C. Improvements in Communication and Coordination of Care in a Hemophilia Treatment Center. Acta Haematol. 2021 Apr 29;:1-6. [Epub ahead of print] PubMed PMID: 33915533
• Maher KN, Gibson E, Warren BB, Funk SM, Shearer R, Buckner TW, Wang M, Manco-Johnson MJ, Ng CJ. Prophylaxis for children with moderate hemophilia: Use of a guideline to increase early initiation. Pediatr Blood Cancer. 2021 Jan;68(1):e28577. PubMed PMID: 32881253
• 14. Christopher J Ng, Alice Liu, Sujatha Venkataraman, Katrina Ashworth , Christopher D.Baker, Rebecca O’Rourke, Rajeev Vibhakar, Kenneth L. Jones and Jorge Di Paola. Single Cell Transcriptional Analysis of Human Endothelial Colony Forming Cells from Patients with Low VWF Levels. BLD-2021-010683R2. Blood (accepted).
• Warren BB, Chan A, Manco-Johnson M, Branchford BR, Buckner TW, Moyer G, Gibson E, Thornhill D, Wang M, Ng CJ. Emicizumab initiation and bleeding outcomes in people with hemophilia A with and without inhibitors: A single-center report. Res Pract Thromb Haemost. 2021 Jul;5(5):e12571. PubMed PMID: 34377887
• Kristin Maher, MD, PhD and Christopher Ng, MD. Diagnosis and Management of von Willebrand Disease. An Educational Slide Set. ASH ISTH NHF WFH 2021 Guidelines for Diagnosis and Management of von Willebrand Disease.
• Maher KN, Gibson E, Warren BB, Funk SM, Shearer R, Buckner TW, Wang M, Manco-Johnson MJ, Ng CJ. Prophylaxis for children with moderate hemophilia: Use of a guideline to increase early initiation. Pediatr Blood Cancer. 2020 Sep 2;:e28577. [Epub ahead of print] PubMed PMID: 32881253
• Rao ES, Ng CJ. Current approaches to diagnostic testing in von Willebrand Disease. Transfus Apher Sci. 2018 Aug;57(4):463-465. PubMed PMID: 30064913
• Ng CJ, McCrae KR, Ashworth K, Sosa LJ, Betapudi V, Manco-Johnson MJ, Liu A, Dong JF, Chung D, White-Adams TC, López JA, Di Paola J. Effects of anti-ß2GPI antibodies on VWF release from human umbilical vein endothelial cells and ADAMTS13 activity. Res Pract Thromb Haemost. 2018 Apr;2(2):380-389. PubMed PMID: 30046742
• Ng CJ, Di Paola J. von Willebrand Disease: Diagnostic Strategies and Treatment Options. Pediatr Clin North Am. 2018 Jun;65(3):527-541. PubMed PMID: 29803281
• Lehmann M, Ashworth K, Manco-Johnson M, Di Paola J, Neeves KB, Ng CJ. Evaluation of a microfluidic flow assay to screen for von Willebrand disease and low von Willebrand factor levels. J Thromb Haemost. 2018 Jan;16(1):104-115. PubMed PMID: 29064615
• Lehmann M, Ashworth K, Manco-Johnson M, Di Paola J, Neeves KB, Ng CJ. Evaluation of a microfluidic flow assay to screen for von Willebrand disease and low von Willebrand factor levels. J Thromb Haemost. 2017 Oct 24. [Epub ahead of print] PubMed PMID: 29064615
• Branchford BR, Stalker TJ, Law L, Acevedo G, Sather S, Brzezinski C, Wilson KM, Minson K, Lee-Sherick AB, Davizon-Castillo P, Ng C, Zhang W, Neeves KB, Lentz SR, Wang X, Frye SV, Earp HS, DeRyckere D, Brass LF, Graham DK, Di Paola JA. The small molecule MERTK inhibitor UNC2025 decreases platelet activation and prevents thrombosis. J Thromb Haemost. 2017 Oct 17. [Epub ahead of print] PubMed PMID: 29045015
• Moreira DC, Ng CJ, Quinones R, Liang X, Chung DW, Di Paola J. Microangiopathic hemolytic anemia due to ADAMTS-13 loss in idiopathic systemic capillary leak syndrome. J Thromb Haemost. 2016 Sep 13. [Epub ahead of print] PubMed PMID: 27622772
• White-Adams TC, Ng CJ, Jacobi PM, Haberichter SL, Di Paola JA. Mutations in the D'D3 region of VWF traditionally associated with type 1 VWD lead to quantitative and qualitative deficiencies of VWF. Thromb Res. 2016 Sep;145:112-8. PubMed PMID: 27533707
• Branchford BR, Ng CJ, Neeves KB, Di Paola J. Microfluidic technology as an emerging clinical tool to evaluate thrombosis and hemostasis. Thromb Res. 2015 Jul;136(1):13-9. PubMed PMID: 26014643
• Ng C, Motto DG, Di Paola J. Diagnostic approach to von Willebrand disease. Blood. 2015 Mar 26;125(13):2029-37. PubMed PMID: 25712990