Mingxia Huang, PhD

Visiting Associate Research Professor, Anesthesiology


FacultyPhoto
Department
Anesthesiology

Publications

  • Wu, X., Liu, L and Huang. M (2010) Checkpoint Studies Using the Budding Yeast Saccharomyces cerevisiae. Cell Cycle Checkpoints: Methods and Protocols by Humana Press.
  • Wu, X., Liu, L and Huang. M (2011) Checkpoint Studies Using the Budding Yeast Saccharomyces cerevisiae. Cell Cycle Checkpoints: Methods and Protocols by Humana Press.
  • Zhang, Y., Liu, L., Wu, X., An, X., Stubbe, J. and Huang, M. (2011) Investigation of in vivo diferric tyrosyl radical formation in Saccharomyces cerevisiae Rnr2: requirement of Rnr4 and contribution of Grx3/4 and Dre2. J. Biol. Chem. 286, 41499-41509. (selected as paper of the week). PMID 21931161.
  • Sanvisens, N., Bañó. C., Huang, M. and Puig, S. (2011) Regulation of ribonucleotide reductase in response to iron deficiency. Mol. Cell, 44, 759-769. (This paper was accompanied with a Preview in the same issue)
  • Ahmad, M.F, Kaushal, P.S., Wan, Q., Wijerathna, S.R., An, X., Huang, M., and Dealwis, C. G. (2012) Role of arginine-293 and glutamine-288 in communication between catalytic and allosteric sites in yeast ribonucleotide reductase. J. Mol. Biol. (epub Mar 29, 2012)
  • Zhang, Y., An, X., Stubbe, J., and Huang, M. (2013) Investigation of in vivo roles of the carboxyl terminal tails of the small subunit (ßß') of S. cerevisiae ribonucleotide reductase: contribution to cofactor formation and inter-subunit association within the active holoenzyme. J. Biol. Chem. Epub. 2013 Mar. 26. (This paper was selected as Paper of the Week)
  • Zhang, Y., An, X., Stubbe, J., and Huang, M. (2013) Investigation of in vivo roles of the carboxyl terminal tails of the small subunit (ßß') of S. cerevisiae ribonucleotide reductase: contribution to cofactor formation and inter-subunit association within the active holoenzyme. J. Biol. Chem. 288, 13951-13959. (This paper was selected as Paper of the Week)
  • Zhang, Y*., Li, H*., Zhang, C*., An, X., Liu, L., Stubbe, J.*, and Huang, M*. (2014) The conserved electron donor complex Dre2-Tah18 is required for ribonucleotide reductase metallocofactor assembly and DNA synthesis. Proc. Natl. Acad. Sci. (Epub week of 4/14/14)
  • Zhang, C., Liu, G., and Huang, M. (2014) Ribonucleotide reductase metallocofactor: assembly, maintenance, and inhibition. Front. Biol. Vol 9(2) In press April 2014.
  • Liu L, Huang M. Essential role of the iron-sulfur cluster binding domain of the primase regulatory subunit Pri2 in DNA replication initiation. Protein Cell. 2015 Mar;6(3):194-210. PubMed PMID: 25645023
  • Sanvisens N, Romero AM, An X, Zhang C, de Llanos R, Martínez-Pastor MT, Bañó MC, Huang M, Puig S. Yeast Dun1 kinase regulates ribonucleotide reductase inhibitor Sml1 in response to iron deficiency. Mol Cell Biol. 2014 Sep;34(17):3259-71. PubMed PMID: 24958100
  • Zhang Y, Li H, Zhang C, An X, Liu L, Stubbe J, Huang M. Conserved electron donor complex Dre2-Tah18 is required for ribonucleotide reductase metallocofactor assembly and DNA synthesis. Proc Natl Acad Sci U S A. 2014 Apr 29;111(17):E1695-704. PubMed PMID: 24733891
  • Zhang C, Liu G, Huang M. Ribonucleotide reductase metallocofactor: assembly, maintenance and inhibition. Front Biol (Beijing). 2014 Jan 2;9(2):104-113. PubMed PMID: 24899886
  • Liu L, Huang M. Essential role of the iron-sulfur cluster binding domain of the primase regulatory subunit Pri2 in DNA replication initiation. Protein Cell. 2015 Mar;6(3):194-210. PubMed PMID: 25645023
  • An X, Zhang C, Sclafani RA, Seligman P, Huang M. The late-annotated small ORF LSO1 is a target gene of the iron regulon of Saccharomyces cerevisiae. Microbiologyopen. 2015 Dec;4(6):941-51. PubMed PMID: 26450372
  • Huang M, Parker MJ, Stubbe J. Choosing the right metal: case studies of class I ribonucleotide reductases. J Biol Chem. 2014 Oct 10;289(41):28104-11. PubMed PMID: 25160629
  • Li H, Stümpfig M, Zhang C, An X, Stubbe J, Lill R, Huang M. The diferric-tyrosyl radical cluster of ribonucleotide reductase and cytosolic iron-sulfur clusters have distinct and similar biogenesis requirements. J Biol Chem. 2017 Jul 7;292(27):11445-11451. PubMed PMID: 28515324
  • Blevins MA, Huang M, Zhao R. The Role of CtBP1 in Oncogenic Processes and Its Potential as a Therapeutic Target. Mol Cancer Ther. 2017 Jun;16(6):981-990. PubMed PMID: 28576945
  • Wu X, An X, Zhang C, Huang M. Clb6-Cdc28 Promotes Ribonucleotide Reductase Subcellular Redistribution during S Phase. Mol Cell Biol. 2018 Mar 15;38(6). PubMed PMID: 29263158
  • "C-terminal binding proteins 1 and 2 in traumatic brain injury-induced inflammation and their inhibition as an approach for anti-inflammatory treatment" International Journal of Biological Sciences, accepted for publication November 2019.
  • "C-terminal binding proteins 1 and 2 in traumatic brain injury-induced inflammation and their inhibition as an approach for anti-inflammatory treatment" Int J Biol Sci 2020; 16(7):1107-1120. doi:10.7150/ijbs.42109
  • Li H, Zhang C, Bian L, Deng H, Blevins M, Han G, Fan B, Yang C, Zhao R, High W, Norris D, Fujita M, Wang XJ, Huang M. Inhibition of CtBP-Regulated Proinflammatory Gene Transcription Attenuates Psoriatic Skin Inflammation. J Invest Dermatol. 2022 Feb;142(2):390-401. PubMed PMID: 34293351